• Title/Summary/Keyword: Nano-safety

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Effect of Powder Condition on the Fire and Explosion Characteristics of Suspended and Deposited Dusts (부유 및 퇴적의 분체 조건이 화재폭발 특성에 미치는 영향)

  • Han, Ou-Sup;Seo, Dong-Hyun;Choi, Yi-Rac;Lim, Jin-Ho
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.229-236
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    • 2022
  • An experimental investigation was conducted on the influences of median size, dust concentration, dust condition (cloud and layer) for the fire and explosion hazard assessment of dusts with the same powder property. For this purpose, tests have been performed in accordance with 20 L explosion sphere, thermogravi- metric analyze, combustion rate tester (UN method). We investigated the explosion characteristics and flame propagation velocity (FPV) in dust cloud and the flame spread velocity(FSV) over dust layer on 8 dust samples with different particle sizes of 4 types of dusts (Sugar, Mg, Al, Zr). An explosion hazard increased with decreasing particle size in Mg and Al dust clouds, but sugar did not show the effect of explosion hazard due to particle size change in dust clouds. The flame propagation velocity (FPV) of suspended dusts increased significantly when the particle size decreased from micro to nano than the variation of particle size in micro range. The flame spread velocity (FSV) over dust layer showed a tendency to increase over the inclined dust layers (30° slope) rather than the horizontal dust layers (0° slope). The flame spread rate (FSV) over dust layers increased on the inclined dust layer (30° slope) rather than the horizontal dust layer (0° slope) and was higher upward flame than the downward flame in condition of inclined dust layers(30° slope).

A Study for Development of Smart Taekwondo Uniform with Enhanced Functionality for Children (기능성이 향상된 아동용 스마트 태권도복 개발을 위한 연구)

  • Kim, Kyung-A
    • Journal of the Korea Fashion and Costume Design Association
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    • v.11 no.2
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    • pp.169-181
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    • 2009
  • The purpose of this study was to provide basic information for developing a smart taekwondo uniform with enhanced functionality for children by investigating the wearing condition and satisfaction of taekwondo uniform among taekwondo training children. The data were collected from 162 children living in Seoul and Daegu. For data analysis were performed descriptive statistics, ${\chi}2$ -test and t-test using SPSS Ver. 12. The results of the analysis are as follows. The results revealed that respondents wearing the general training uniform during their training period were the most. The dissatisfaction for the general training uniform was a high price, lack of symbolic, lack of functionality in textiles, lack of variety in design and unfittness of size in order. The developed uniform can adjust the length using a zipper type fastener, and can be used in all seasons as the lining is detachable. It also uses nano-silver material, and soil release finish. It enhances the functionality of movement by treating with raglan sleeve and sleeve hem velcro tape, and designs the upper garment in the draping. Safety is improved through attaching GPS, and elastic material is mixed in the neckline for putting on and off easily. Piece of cloth is added inside the closing of the upper garment. Rings are made for fixing the taekwondo uniform belt. Pocket is designed in the lower garment and colors are multiplied.

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Multi-walled Carbon Nanotubes Affect the Morphology and Membrane Potential of Mitochondria in HeLa Cell

  • Lee, Wonwoo;Cho, Hyo Min;Oh, Chung Seok;Kim, Eun Hae;Sun, Woong
    • Applied Microscopy
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    • v.44 no.2
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    • pp.68-73
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    • 2014
  • With wide use of nano-materials, it is increasingly important to address their potential toxicity to mammalian cells. However, toxic effects of these materials have been mainly assessed by the cell survival assays. Considering that mitochondrial morphology and quality are highly sensitive to the condition of the cells, and the impairment of mitochondrial function greatly affect the survival of cells, here we tested the impact of multi-walled carbon nanotubes (MWNT) on the survival, mitochondrial morphology, and their membrane potential in HeLa cells. Interestingly, although MWNT did not induce cell death until 24 hours as assessed by pyknotic cell assay, mitochondrial length was elongated and the mitochondrial membrane potential was significantly reduced by exposure of HeLa cells to MWNT. These results suggest that MWNT exposure is potentially harmful to the cell, and the mechanism how MWNT alters mitochondrial quality should be further explored to assess the safety of MWNT use.

Ultra Sensitive Detection of H2 in ZnO QD-based Sensors (ZnO양자점 기반 센서의 초고감도 수소 검지 특성)

  • Lee, Hyun-Sook;Kim, Wonkyung;Lee, Wooyoung
    • Journal of Sensor Science and Technology
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    • v.29 no.2
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    • pp.105-111
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    • 2020
  • Interest and demand for hydrogen sensors are increasing in the field of H2 leakage detection during storage/transport/use and detection of H2 dissolved in transformer oil for safety issues as well as in the field of breath analysis for non-invasively diagnosing a number of disease states for a healthy life. In this study, various ZnO-based sensors were synthesized by controlling the reduction in crystallite size, decoration of Pt nanoparticles, doping of electron donating atoms, and doping of various atoms with different ionic radii. The sensing response of the various prepared ZnO-based nanoparticles and quantum dots (QDs) for 10 ppm H2 was investigated. Among the samples, the smallest-sized (3.5 nm) In3+-doped ZnO QDs showed the best sensing response, which is superior to those in previously reported hydrogen sensors based on semiconducting metal oxides. The higher sensing response of In-doped ZnO QDs is attributed to the synergic effects of the increased number of oxygen vacancies, higher optical band gap, and larger specific surface area.

Improvement of Sensitivity to In-plane Strain/Deformation Measurement by Micro-ESPI Technique (마이크로 ESPI 기법에 의한 면내 변형 측정 민감도 향상)

  • Kim D.I.;Huh Y.H.;Kee C.D.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1442-1445
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    • 2005
  • Several test methods, including micro strain/deformation measurement techniques, have been studied to more reliably measure the micro properties in micro/nano materials. Therefore, in this study, the continuous measurement of in-plane tensile strain in micro-sized specimens of thin film materials was introduced using the micro-ESPI technique. TiN and Au thin films 1 and $0.47\;\mu{m}$ thick, respectively, were deposited on the silicon wafer and fabricated into the micro-sized tensile specimens using the electromachining process. The micro-tensile loading system and micro-ESPI system were developed to measure the tensile strain during micro-tensile test. The micro-tensile stress-strain for these materials was determined using the algorithm for continuous strain measurement. Furthermore, algorithm for enhancing the sensitivity to measurement of in-plane tensile strain was suggested. According to the algorithm for enhancement of sensitivity, micro-tensile strain data between interfringe were calculated. It is shown that the algorithm for enhancement of the sensitivity suggested in this study makes the sensitivity to the in-plane tensile strain increase.

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Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin $B_{12}$-deficient rats

  • Min, Hye-Sun
    • Nutrition Research and Practice
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    • v.3 no.2
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    • pp.122-127
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    • 2009
  • Folate is generally considered as a safe water-soluble vitamin for supplementation. However, we do not have enough information to confirm the potential effects and safety of folate supplementation and the interaction with vitamin $B_{12}$ deficiency. It has been hypothesized that a greater methyl group supply could lead to compensation for vitamin $B_{12}$ deficiency. On this basis, the present study was conducted to examine the effects of high-dose folic acid (FA) supplementation on biomarkers involved in the methionine cycle in vitamin $B_{12}$-deficient rats. Sprague-Dawley rats were fed diets containing either 0 or $100{\mu}g$ (daily dietary requirement) vitamin $B_{12}/kg$ diet with either 2 mg (daily dietary requirement) or 100 mg FA/kg diet for six weeks. Vitamin $B_{12}$-deficiency resulted in increased plasma homocysteine (p<0.01), which was normalized by dietary supplementation of high-dose FA (p<0.01). However, FA supplementation and vitamin $B_{12}$ deficiency did not alter hepatic and brain S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) concentrations and hepatic DNA methylation. These results indicated that supplementation of high-dose FA improved homocysteinemia in vitamin $B_{12}$-deficiency but did not change SAM and SAH, the main biomarkers of methylating reaction.

Displacement Properties of Nano Structure Dendrimer

  • Song Jin-Won;Lee Kyung-Sup;Lee Woo-Ki;Choi Young-Il;Yoon Suk-Am;Choi Chung-Seog
    • KIEE International Transactions on Electrophysics and Applications
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    • v.5C no.1
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    • pp.28-32
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    • 2005
  • In the Langmuir-Blodgett (LB) technique, a monolayer on the water surface is transferred onto a substrate, which is raised and dipped through the surface. From this, multilayers can be obtained in which constituent molecules are periodically arranged. The LB technique has attracted considerable interest in the fabrication of electrical and electronic devices. Many researchers have investigated the electrical properties of monolayer and multiplayer films. Dendrimers represent a new class of synthetic macromolecules characterized by a regularly branched treelike structure. Multiple branching yields a large number of chain ends that distinguish dendrimers from conventional star-like polymers and microgels. The azobenzene dendrimer is one of the dendritic macromolecules that include the azo-group exhibiting a photochromic character. Due to the presence of the charge transfer element of the azo-group and its rod-shaped structure, these compounds are expected to have potential interest in electronics and ptoelectronics, especially in nonlinear optics. In the present paper, we give pressure stimulation to organic thin films and detect the induced displacement current.

Catalytic Reactor of Hydrogen Peroxide for a Micro Thruster (마이크로 추력장치용 과산화수소 촉매 반응기)

  • Lee, Dae-Hun;Cho, Jeong-Hun;Kwon, Se-Jin
    • 한국연소학회:학술대회논문집
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    • 2002.11a
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    • pp.237-240
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    • 2002
  • Micro catalytic reactors are alternative propulsion device that can be used on a nano satellite. When used with a monopropellant, $H_2O_2$, a micro catalytic reactor needs only one supply system as the monopropellant reacts spontaneously on contact with catalyst and releases heat without external ignition, while separate supply lines for fuel and oxidizer are needed for a bipropellant rocket engine. Additionally, $H_2O_2$ is in liquid phase at room temperature, eliminating the burden of storage for gaseous fuel and carburetion of liquid fuel. In order to design a micro catalytic reactor, an appropriate catalyst material must be selected. Considering the safety concern in handling the monopropellants and reaction performance of catalyst, we selected hydrogen peroxide at volume concentration of 70% and perovskite redox catalyst of lantanium cobaltate doped with strondium. Perovskite catalysts are known to have superior reactivity in reduction-oxidation chemical processes. In particular, lantanium cobaltate has better performance in chemical reactions involving oxygen atom exchange than other perovskite materials. In the present study, a process to prepare perovskite type catalyst, $La_{0.8}Sr_{0.2}CoO_3$, and measurement of its propellant decomposition performance in a test reactor are described.

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The Power of Being Small: Nanosized Products for Agriculture

  • Anderson, Anne J.
    • Research in Plant Disease
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    • v.24 no.2
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    • pp.99-112
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    • 2018
  • Certain agrochemicals may be tuned for increased effectiveness when downsized to nanoparticles (NPs), where one dimension is less than 100 nm. The NPs may function as fertilizers, pesticides and products to improve plant health through seed priming, growth promotion, and induction of systemic tolerance to stress. Formulations will allow targeted applications with timed release, reducing waste and pollution when compared to treatments with bulk-size products. The NPs may be a single component, such as nano-ZnO as a fertilizer, or be composites of compatible materials, for example where N, P, and K plus micronutrients are available. The active materials could be loaded into porous carriers or tethered to base nanostructures. Coatings could include such natural products alginate, chitosan, zein, or silica. Certain NPs are taken up and transported in the plant's phloem and xylem so systemic effects are feasible. Timed and targeted release of the active product could be achieved in response to changes in pH or availability of ligands within the plant or the rhizosphere. Global research has revealed the many potentials offered by NP formulations to aid sustainability in agriculture. Current work will provide information needed by regulatory agencies to assess their safety in the agricultural setting.

MS Platform for Erythropoietin Glycome Characterization

  • Seo, Youngsuk;Kim, Unyong;Oh, Myung Jin;Yun, Na Young;An, Hyun Joo
    • Mass Spectrometry Letters
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    • v.6 no.3
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    • pp.53-58
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    • 2015
  • Recombinant erythropoietins (EPOs) are an important class of biotherapeutics that stimulate red blood cell production. The quality, safety, and potency of EPO variants are determined largely by their glycosylation, which makes up nearly half their mass. Thus, detailed glycomic analyses are important to assess biotherapeutic quality and establish the equivalency of biosimilar EPOs now coming to market. High-resolution mass spectrometry (MS) has recently emerged as the premier tool for glycan analysis in EPOs. Using the accurate mass measurements provided by high-resolution MS, the compositions of even large, complex glycans can easily be determined. When combined with a nano-LC separation, differentiation of structural isomers also becomes a possibility. These components, together, provide a comprehensive picture of biotherapeutic glycosylation. In this review, we provide an overview of MS-based analytical platform for glycomic characterization of EPO biotherapeutics and biosimilars.