• 대한화학회지
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• 제22권5호
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• pp.281-288
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• 1978

1-염화 및 2-염화나프탈렌술포닐과 아닐린과의 반응에서 그 반응의 유사 일차 반응속도상수($k_{obs}$)를 구하고 또한 2차 반응속도 상수 $k_2$및 3차반응 촉매속도상수 $k_3$도 $k_{obs}$로 부터 구하였다. 1-염화나프탈렌술포닐과의 반응에서는 Peri-hydrogen 효과가 관측되었다. 또한 Brensted 그림표에서는 큰 값의 ${\beta}$와 Hammett 그림표의 기울기로부터 크 음의 ${\rho}$값을 얻었다. 따라서 이 반응의 메카니즘은 매우 낮은 활성화파라미터의 값을 갖는 결과로$S_AN$반응메카니즘과 잘 일치되지만 associative$S_N2$메카니즘으로도 동일하게 잘 설명될 수 있었다.

• 한국구조물진단유지관리공학회 논문집
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• 제9권1호
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• pp.205-215
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• 2005

본 연구에서는 콘크리트 보의 전단거동에서 콘크리트 압축강도가 스터럽 유효성에 미치는 영향을 실험적으로 연구하였다. 전단파괴와 휨파괴가 동시에 일어나는 경계점은 대략 S=150mm부근으로 예상되며, 이때 전단철근비는 보통강도 콘크리트보에서는 $0.63{\rho}_{vmax}$ 이고, 고강도 콘크리트보에서는 $0.53{\rho}_{vmax}$로서 ACI 전단설계 산정식은 매우 안전측이라고 판단된다.

• Applied Microscopy
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• 제28권4호
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• pp.591-601
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• 1998

The neurotoxic effects of radiation have been studied in NSC-34 hybrid cells derived from embryonic mouse spinal cord cells. NSC-34 cells irradiated at 25Gy were decreased the cell viability in a time and dose dependent manner. The decrease in cell viability induced by the irradiation was blocked by catalase. Antagonists of the N-methyl-D-aspartate (NMDA) receptor, including D-2-amino-5-phosphonovaleric acid (APV) and chlorokynurenic acid (CKA), similarly blocked radiational induced in cell viability. We performed morphological analysis of light and electron microscope. NSC-34 cells irradiated at 25Gy were decreased the cell density and increased lysosomes and vacuoles in the cytoplasm. Especially chromatin modification was observed. These results indicated that radiation was involved in the oxidant-initiated neurotoxicity and the compounds catalase, APV and CKA were shown to be neuroprotective against radiation.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 봄 학술논문 발표대회
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• pp.297-298
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• 2023

In the concrete industry, efforts are being made to reduce CO₂ emissions, and technologies that collect, store, and utilize CO₂ have recently been studied. This study analyzed the change in compressive strength after the accelerated carbonation test of Non-Sintered Cement(NSC) mortar. Type C Fly Ash and Type F Fly Ash were mixed in a 1:1 ratio and then mixed with Blast Furnace Slag fine powder to produce NSC. The mortar produced was cured underwater until the target age. In addition, an accelerated carbonation test was conducted under the condition of a concentration of 5 (±1.0%) of CO₂ gas for 14 days. The mortar compressive strength was measured before and after 14 days of accelerated carbonation test based on the 7th and 28th days of age. As a result of the experiment, the compressive strength was improved in all binder. In general, the compressive strength of NSC mortar subjected to the accelerated carbonation test was similar to that of Ordinary Portland Cement(OPC) mortar not subjected to the accelerated carbonation test.

• Journal of Korean Neurosurgical Society
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• 제56권5호
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• pp.383-389
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• 2014

Objective : Neural tissue transplantation has been a promising strategy for the treatment of Parkinson's disease (PD). However, transplantation has the disadvantages of low-cell survival and/or development of dyskinesia. Transplantation of cell aggregates has the potential to overcome these problems, because the cells can extend their axons into the host brain and establish synaptic connections with host neurons. In this present study, aggregates of human brain-derived neural stem cells (HB-NSC) were transplanted into a PD animal model and compared to previous report on transplantation of single-cell suspensions. Methods : Rats received an injection of 6-OHDA into the right medial forebrain bundle to generate the PD model and followed by injections of PBS only, or HB-NSC aggregates in PBS into the ipsilateral striatum. Behavioral tests, multitracer (2-deoxy-2-[$^{18}F$]-fluoro-D-glucose ([$^{18}F$]-FDG) and [$^{18}F$]-N-(3-fluoropropyl)-2-carbomethoxy-3-(4-iodophenyl)nortropane ([$^{18}F$]-FP-CIT) microPET scans, as well as immunohistochemical (IHC) and immunofluorescent (IF) staining were conducted to evaluate the results. Results : The stepping test showed significant improvement of contralateral forelimb control in the HB-NSC group from 6-10 weeks compared to the control group (p<0.05). [$^{18}F$]-FP-CIT microPET at 10 weeks posttransplantation demonstrated a significant increase in uptake in the HB-NSC group compared to pretransplantation (p<0.05). In IHC and IF staining, tyrosine hydroxylase and human ${\beta}2$ microglobulin (a human cell marker) positive cells were visualized at the transplant site. Conclusion : These results suggest that the HB-NSC aggregates can survive in the striatum and exert therapeutic effects in a PD model by secreting dopamine.

• Nuclear Engineering and Technology
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• 제18권2호
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• pp.97-106
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• 1986

1981년 6일 9일 원자력 1호기에서 발생한 77.5% 출력상태에서의 외부전원상실사고를 열, 수력학적최적계산용 코드인 RELAP5/MODl/NSC를 사용하여 모의하였으며 해석결과는 발전소 실측자료와 잘 일치하였다. 원자로 냉각재펌프의 트립에 따른 flow coastdown후에 hot-cold leg온도차에 의하여 자연순환 유동이 형성됨이 확인되었으며 실측자료와 잘 일치하여 이와 관련된 전산코드의 열수력학 적모델의 타당성을 입증할 수 있었다. 또한 위의 사고전개가 정상운전상태인 전출력(100%)에서 재발하였을 경우를 가정하여 해석하였다. 이러한 해석을 통하여 보조급수의 공급과 더불어 증기발생기 PORV의 적절한 작동으로 원자력 1호기 노심잔열을 제거하여 안전성에 문제점을 야기하지 않음을 입증하였다. 최적 계산방법에 의한 사고해석에서는 turbine stop valve 작동시간, 증기 발생기 PORV 설정치 등 non-safety 관련요소들의 특성에 대한 정화한 모의가 필수적이다.

• 국방과기술
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• 7호통권113호
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• pp.38-47
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• 1988

• 국방과기술
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• 6호통권112호
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• pp.12-20
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• 1988

• 월간피드저널
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• 제5권10호통권50호
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• pp.65-68
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• 2007

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 춘계 학술발표회 제16권1호
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• pp.232-235
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• 2004

This study aims to manufacture non-sintering cement(NSC) by adding phosphogypsum(PG) and waste lime(WL) to granulated blast furnace slag(GBFS) as sulfate and alkali activators. This study also investigates the basic physical properties and hydration reaction of NSC, and evaluates its reusing possibility as construction material. Results obtained from this study have shown that GBFS was affected by $So_4^{2-}$ in waste PG and stimuli under wet condition, left slag components, created Ettringite and CSH gels, and eventually started being hydrated. These hydrated creations formed dense structures like CSH based on Ettringite and contributed in allowing the mortar to reveal high strength.