• 지구물리
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• 제10권1호
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• pp.37-44
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• 2007

최근 인간의 지적 욕구 충족과 급속한 과학 기술의 발전으로 새로운 측위 시스템인 광역위성항법시스템이 개발되었다. 위치정보 산업은 과거 군사적인 목적뿐만 아니라 민간 목적으로 폭넓게 사용되고 있다. 이는 차량 및 항공 항법, 토목공사, GIS의 자료원, 텔레메틱스, 위치기반서비스 등에서 단순한 측위 시스템의 기능이 아닌 사회 기반 시설의 역할을 담당하고 있다. 미국에 의한 고의적 잡음은 해제되었지만, GPS의 독점과 의존은 절대적이다. 이에 본 연구에서는 순수민간 목적으로 제작되고 서비스 할 예정인 차세대 NSS인 유럽의 Galileo의 영향을 연구하기 위해 소프트웨어를 개발하였으며 이를 바탕으로 측위 기법별 분석을 통해 우리나라에 미치는 실질적인 영향을 분석하였다. 또한 위성수신고 도각을 높게 설정하여 도심지와 같은 차폐환경에서 GPS 단독처리에 의한 방법보다 GPS/Galileo 조합 형태의 우수성을 입증하였다.

• Archives of Pharmacal Research
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• 제28권10호
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• pp.1170-1176
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• 2005

2-Methyl-2-(2-methylpropenyl)-2,3-dihydronaphthoquinone[2,3-b]furan-4,9-dione (N FD-37) is a synthetic furonaphthoquinone compound. In this study, we determined that NFD-37 could inhibit the lipopolysaccharide (LPS)-induced production of inflammatory mediators in macrophages RAW 264.7. This compound inhibited LPS-induced nitric oxide (NO) or prostaglandin (PG) $E_{2}$ production in dose-dependent manners, with $IC_{50}$ values of 7.2 ${\mu}M$ and 5.3 ${\mu}m$, respectively. As the positive controls, pyrrolidine dithiocarbamate (30 ${\mu}M$) exhibited a $57{\%}$ inhibition of NO production, and NS-398 ($1{\mu}M$) manifested a $48{\%}$ inhibition of $PGE_2$ production. The inhibitory effects of NFD-37 on NO and $PGE_2$ production were determined to occur in conjunction with the suppression of inducible NO synthase or cyclooxygenase-2 expression. NFD-37 also inhibited the production of LPS-inducible tumor necrosis factor-${\alpha}$, interleukin (IL)-$1{\beta}$ and IL-6, at $IC_{50}$ values of 4.8-8.9 ${\mu}M$. We also determined the anti-inflammatory efficacy of NFD-37 using carrageenin-induced paw edema in experimental mice.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.403-404
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• 2013

최근 scaling down의 한계에 부딪힌 DRAM과 Flash Memory를 대체하기 위한 차세대 메모리(Next Generation Memory)에 대한 연구가 활발히 진행되고 있다. ITRS (international technology roadmap for semiconductors)에 따르면 PRAM (phase change RAM), RRAM (resistive RAM), STT-MRAM (spin transfer torque magnetic RAM) 등이 차세대 메모리로써 부상하고 있다. 그 중 RRAM은 간단한 구조로 인한 고집적화, 빠른 program/erase 속도 (100~10 ns), 낮은 동작 전압 등의 장점을 갖고 있어 다른 차세대 메모리 중에서도 높은 평가를 받고 있다 [1]. 현재 RRAM은 주로 금속-산화물계(Metal-Oxide) 저항 변화 물질을 기반으로 연구가 활발하게 진행되고 있다. 하지만 근본적으로 공정 과정에서 산소에 의한 오염으로 인해 수율이 낮은 문제를 갖고 있으며, Endurance 및 Retention 등의 신뢰성이 떨어지는 단점이 있다. 따라서, 본 연구진은 산소 오염에 의한 신뢰성 문제를 근본적으로 해결할 수 있는 다양한 금속-질화물(Metal-Nitride) 기반의 저항 변화 물질을 제안해 연구를 진행하고 있으며, 우수한 열적 안정성($>450^{\circ}C$, 높은 종횡비, Cu 확산 방지 역할, 높은 공정 호환성 [2] 등의 장점을 가진 WN 박막을 저항 변화 물질로 사용하여 저항 변화 메모리를 구현하기 위한 연구를 진행하였다. WN 박막은 RF magnetron sputtering 방법을 사용하여 Ar/$N_2$ 가스를 20/30 sccm, 동작 압력 20 mTorr 조건에서 120 nm 의 두께로 증착하였고, E-beam Evaporation 방법을 통하여 Ti 상부 전극을 100 nm 증착하였다. I-V 실험결과, WN 기반의 RRAM은 양전압에서 SET 동작이 일어나며, 음전압에서 RESET 동작을 하는 bipolar 스위칭 특성을 보였으며, 읽기 전압 0.1 V에서 ~1 order의 저항비를 확보하였다. 신뢰성 분석 결과, $10^3$번의 Endurance 특성 및 $10^5$초의 긴 Retention time을 확보할 수 있었다. 또한, 고저항 상태에서는 Space-charge-limited Conduction, 저저항 상태에서는 Ohmic Conduction의 전도 특성을 보임에 따라 저항 변화 메카니즘이 filamentary conduction model로 확인되었다 [3]. 본 연구에서 개발한 WN 기반의 RRAM은 우수한 저항 변화 특성과 함께 높은 재료적 안정성, 그리고 기존 반도체 공정 호환성이 매우 높은 강점을 갖고 있어 핵심적인 차세대 메모리가 될 것으로 기대된다.

• Journal of Acupuncture Research
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• 제18권2호
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• pp.200-213
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• 2001

Objectives : This study was purposed to investigate the Anti-inflammatory and Analgesic Effects of Gold injection Aqua-acupuncture on the experimental model of rheumatoid arthritis. Methods : The experimental groups were divided into 4 groups : Control group (group injected with normal saline), J-NS (group injected with normal saline into bilateral Choksamni(ST36)), J-GS (group injected with Gold Injection into bilateral Choksamni(ST36)), and N-GS (injected with Gold Injection into the blank locus of the root of mouse tail). In addition, Diclofenac-Na as a comparative medicine is injected into bilateral Choksamni(ST36) and the blank locus of the root of mouse tail. So we measured the mice paw edema induced by Carrageenin and Dextran, the chronic rat paw edema induced by adjuvant, vascular permeability induced by Acetic acid in mice, the writhing syndrome induced by Acetic acid in mice, the heat-induced pain threshold in mice. Results : The following result have been obtained. 1. The mice paw edema induced by Carrageenin was significantly decreased in J-GS as compared with the control group. 2. The mice paw edema induced by Dextran was significantly decreased in J-GS and N-GS as compared with the control group. 3. The chronic rat paw edema induced by Adjuvant was significantly decreased in J-GS and N-GS as compared with the control group. Serum Iron content was significantly decreased in J-GS and N-GS as compared with the control group. But the effect on the Serum Copper contents has no significance statistically. 4. Vascular permeability induced by Acetic acid in mice was significantly decreased in J-GS and N-GS as compared with the control group. 5. The level of Acetic acid-induced Writhing syndrome and Heat-induced Pain Threshold in mice were all significantly decreased in J-GS and N-GS as compared with the control group. Conclusion : According to the result, gold injection aqua-acupuncture has significant anti-inflammatory and analgesic effects on the experimental model of rheumatiod arthiritis.

• 한국공간구조학회논문집
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• 제8권5호
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• pp.75-82
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• 2008

본 연구에서는 최상층면진시스템을 적용한 고층건물의 진동제어 가능성을 검토하여 보았다. 이를 위하여 20층 및 50층 건물을 예제구조물로 선택하였고 El Centro 남북방향 성분을 지진하중으로 사용하여 수치해석을 수행하였다. 그리고 인공풍하중을 사용하여 풍하중에 대한 예제구조물의 사용성을 검토하였다. 면진되는 상부층의 수를 변화시켜가면서 구조물의 응답을 평가함으로써 최적의 면진질량에 대해서 검토하였다. 또한 상부층면진시스템의 고유진동주기 변화에 따른 진동제어성능의 변화를 고정기초구조물과 비교하여 검토하였다. 해석결과 최상층면진시스템은 동조질량감쇠기로서 활용될 수 있으며 풍하중 및 지진하중에 대한 고층건물의 동적응답을 효과적으로 저감시킬 수 있었다.

• 한국지진공학회논문집
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• 제11권6호
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• pp.33-39
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• 2007

2004년 5월 29일 발생한 울진지진에 대해 지진원 상수(지진원기구, 진원깊이, 규모, 지진원 특성 등)를 모멘트텐서 방법을 이용하여 분석하였다. 3종류의 지각모델에 대해 지각응답함수를 구하여 분석에 이용하였다. 또한 최적의 지진원 상수값을 분석하기 위해 3종류의 진앙위치를 고려하여 분석하였다. 관측소의 방위각 분포 및 진앙거리에 대해서 결과값에 약간의 영향을 주었다. 6개의 모멘트텐서 성분을 조합하여 분석한 결과 울진지진은 거의 남북방향의 주향을 가진 전형적인 역단층의 운동에 의해 발생되었다. 분석된 지진원 기구는 울진지진 진앙 주변은 동서방향의 압축방향을 가진 지체역학적인 환경을 가지고 있는 것으로 제시하고 있다. 진원깊이는 약 12km의 값을 가지고 있다. 지진원기구는 기존의 연구결과와 유사하나 진원깊이는 다소 차이가 존재하였다. 이러한 차이는 방법론, 자료 종류 또는 지진원 고유의 기하학적 형태 등에 기인하는 것으로 해석된다.

• 제어로봇시스템학회논문지
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• 제21권7호
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• pp.669-676
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• 2015

In this paper, we described the simulation results of the phase offset performance of a clock in holdover mode which was normally operated in GPS Disciplined Oscillator (GPSDO). In the TIE model, we included the time error term caused by environmental temperature variation because one of the most important parameters of clock phase error is the frequency offset and drift caused by the variation of temperature. For the simulation, we employed Maximum Time Interval Error (MTIE) for the performance evaluation when the frequency offset and drift are estimated by using an Unbiased Finite Impulse Response (UFIR) filter with ladder algorithm. We assumed that the noise in the GPS measurement is white Gaussian with zero mean and 1 ns standard deviation, and temperature linearly varies with a slope of $1{^{\circ}C}$ per hour. From the simulation results, the followings were observed. First, with the estimation error of temperature of less than 3 % and the temperature compensation period of less than 900 seconds, the requirement of CDMA2000 phase synchronization under 10 us could be achieved for more than 40,000 seconds holdover time if we employ an OCXO (Oven Controlled Crystal Oscillator) clock. Second, in order to achieve the requirement of LTE-TDD under 1.5 us for more than 10,000 seconds holdover time, below 3 % estimation error and 500 seconds should be retained if a Rubidium clock is adopted.

• 대한임상검사과학회지
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• 제42권1호
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• pp.1-15
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• 2010

Swine influenza virus (SIV) or swine-origin influenza virus (S-OIV) is endemic in swine, and classified into influenza A and influenza C but not influenza B. Swine influenza A includes H1N1, H1N2, H3N1, H3N2 and H2N3 subtypes. Infection of SIV occurs in only swine and that of S-OIV is rare in human. What human can be infected with S-OIV is called as zoonotic swine flu. Pandemic 2009 swine influenza H1N1 virus (2009 H1N1) was emerged in Mexico, America and Canada and spread worldwide. The triple-reassortant H1N1 resulting from antigenic drift was contained with HA, NA and PB1 of human or swine influenza virus, PB2 and PA polymerase of avian influenza virus, and M, NP and NS of swine influenza virus, The 2009 H1N1 enables to transmit to human and swine. The symptoms and signs in human infected with 2009 H1N1 virus are fever, cough and sore throat, pneumonia as well as diarrhea and vomiting. Co-infection with other viruses and bacteria such as Streptococcus pneumoniae can occur high mortality in high-risk population. 2009 H1N1 virus was easily differentiated from seasonal flu by real time RT-PCR which contributed rapid and confirmed diagnosis. The 2009 H1N1 virus was treated with NA inhibitors such as oseltamivir (Tamiflu) and zanamivir (Relenza) but not with adamantanes such as amantadine and rimantadine. Evolution of influenza virus has continued in various hosts. Development of a more effective vaccine against influenza prototypes is needed to protect new influenza infection such as H5 and H7 subtypes to infect to multi-organ and cause high pathogenicity.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제53권6호
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• pp.330-336
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• 2004

In this work, in order to obtain the detailed information about lightning electromagnetic pulses, the electric fields radiated from multiple lightning return strokes were measured and analyzed statistically. The electric field measuring system consists of a hemisphere antenna of 30cm in diameter, integrator and data acquisition device, and its frequency bandwidth ranges from 200Hz to 1.56MHz, and the sensitivity is 0.96㎷/V/m. The electric field signals are digitized every 200ns with the transient signal analyzer having the resolution of 12-bit and the recording length of 5 kilowords and are registered at personal computer. As a result, the electric fields produced by the first return stroke begin with a slow initial part or front, which starts just after or during the last stepped leader. On the average the rise times of the electric fields for the positive first, second and third strokes are 4.21${\mu}\textrm{s}$, 3.94${\mu}\textrm{s}$ and 2.75${\mu}\textrm{s}$, respectively, and those for the negative first, second and third strokes are 3.46${\mu}\textrm{s}$, 3.15${\mu}\textrm{s}$ and 2.79${\mu}\textrm{s}$, respectively. The zero-crossing times of the electric fields for first return strokes range from about 10 to 80${\mu}\textrm{s}$. The mean zero-crossing times for subsequent return strokes are shorter than those for first lightning return strokes.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제51권6호
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• pp.229-235
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• 2002

This paper presents the fabrication of polycrystalline thin film transistor(TFT) using sequential lateral solidification(SLS) of amorphous silicon. The fabricated SLS TFT showed high Performance suitable for active matrix liquid crystal display(AMLCD). The SLS process involves (1) a complete melting of selected area via irradiation through a patterned mask, and (2) a precisely controlled pulse translation of the sample with respect to the mask over a distance shorter than the super lateral growth(SLG) distance so that lateral growth extended over a number of iterative steps. The SLS experiment was performed with 550$\AA$ a-Si using 308nm XeCl laser having $2\mu\textrm{m}$ width. Irradiated laser energy density is 310mJ/$\textrm{cm}^2$ and pulse duration time was 25ns. The translation distance was 0.6$\mu$m/pulse, 0.8$\mu$m/pulse respectively. As a result, a directly solidified grain was obtained. Thin film transistors (TFTs) were fabricated on the poly-Si film made by SLS process. The characteristics of fabricated SLS p -type poly-Si TFT device with 2$\mu\textrm{m}$ channel width and 2$\mu\textrm{m}$ channel length showed the mobility of 115.5$\textrm{cm}^2$/V.s, the threshold voltage of -1.78V, subthreshold slope of 0.29V/dec, $I_{off}$ current of 7$\times$10$^{-l4}$A at $V_{DS}$ =-0.1V and $I_{on}$ / $I_{off}$ ratio of 2.4$\times$10$^{7}$ at $V_{DS}$ =-0.1V. As a result, SLS TFT showed superior characteristics to conventional poly-Si TFTs with identical geometry.y.y.y.