• Asian-Australasian Journal of Animal Sciences
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• v.17 no.9
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• pp.1236-1240
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• 2004

The objective of this study was to identify the effect of early weaning on body weight change, milk production and the return to estrus in Awassi ewes. Twenty multiparous winter-lambing Awassi ewes were randomly assigned to either suckled (S, n=10) or non-suckled (NS, n=10) groups in a completely randomized design. Lambs in the NS group were removed from their dams on day 2 postpartum (PP). Animal body weights (BW) and body condition scores (BCS) were recorded at the beginning of the study and every 3 weeks thereafter until the end of the experiment. Milk production was estimated by machine milking at weekly intervals for 4 weeks beginning on d 11 PP. Blood samples were collected from each ewe every third day for 4 weeks beginning on day 15 PP. Initial body weight was similar for both treatments. By the end of the experiment, NS ewes gained an average of 1.8${\pm}$1.0 kg while S ewes lost an average of 7.0${\pm}$1.0 kg (p<0.001). Body condition scores followed a trend similar to that observed for BW and was greater (p<0.001) in the NS ewes. Significant correlation existed (p<0.01) between BW and BCS (r=0.77). The first milk production recording for both suckled and non-suckled was similar. Later recordings, however, showed that the S group had greater milk production (p<0.01) compared with the NS group. Lambs in the NS group were heavier (p<0.05) than those in the S group on d 10 PP. By the end of the study, lamb weights in the NS group were significantly lower (p<0.001) when compared with S group. The first rise in plasma progesterone ($P_{4}$) occurred earlier (p<0.05) in the NS than S ewes (day 27.0${\pm}$2.2 vs. 34.0${\pm}$2.2 postpartum, respectively). All of the NS ewes (10/10) and 60% (6/10) of the S ewes expressed estrus following ram introduction (p<0.05). Results of the current study indicate that non-suckled ewes gained more weight and displayed ovarian activity earlier than suckled ewes. Early lamb removal can be used to obtain biannual lambing in Awassi sheep.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.130-130
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• 2022

기후변화로 인한 기상이변 현상으로 폭우와 홍수 등 수문학적 극치 사상의 출현 빈도가 잦아지고 있다. 따라서 이러한 기상이변 현상에 적응하기 위하여 보다 정확한 확률강우량 측정의 필요성이 증가하고 있다. 대장 지점의 미래 확률강우량 계산을 위해선 기후변화 시나리오의 비정상성을 고려해야 한다. 본 연구는 비정상적인 미래 기후에서 확률강우량이 어떻게 변화하는지 측정하는 것을 목표로 한다. Representative Concentration Pathway (RCP4.5)에 따른 우리나라의 확률강우량 계산에 인공신경망을 포함한 정상성, 비정상성 확률강우량 산정 모델들이 사용되었다. 지점빈도해석(AFA), 홍수지수법(IFM), 모분포홍수지수법(PIF), 인공신경망을 이용한 Quantile & Parameter regression technique(QRT & PRT)이 정상성 자료에 대해 확률강우량을 계산하는 모델로 사용되었으며, 비정상성 자료에 대해서는 비정상성 지점빈도해석(NS-AFA), 비정상성 홍수지수법(NS-IFM), 비정상성 모분포홍수지수법(NS-PIF), 인공신경망을 사용한 비정상성 Quantile & Parameter regression technique(NS-QRT & NS-PRT)이 사용되었다. Rescaled Akaike information criterion(rAIC)를 사용한 불확실성 분석과 적합도 검정을 통해서 generalized extreme value(GEV) 분포형 모델이 정상성 및 비정상성 확률강우량 산정에 가장 적합한 모델로 선정되었다. 이후, 관측자료가 GEV(0,0,0)을 따르고 시나리오 자료가 GEV(1,0,0)을 따르는 지점들을 선택하여 미래의 확률강우량 변화를 추정하였다. 각 빈도해석 모델들은 몬테카를로 시뮬레이션을 통해 bias, relative bias(Rbias), root mean square error(RMSE), relative root mean square error(RRMSE)를 바탕으로 측정하여 정확도를 계산하였으며 그 결과 QRT와 NS-QRT가 각각 정상성과 비정상성 자료로부터 가장 정확하게 확률강우량을 계산하였다. 본 연구를 통해 향후 기후변화의 영향으로 확률강우량이 증가할 것으로 예상되며, 비정상성을 고려한 빈도분석 또한 필요함을 제안하였다.

• Annual Conference of KIPS
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• 2014.04a
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• pp.215-217
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• 2014

본 논문에서는 ns-3 기반의 IEEE 802.15.4 모의 성능 평가에 대해 기술한다. IT 기술의 발달과 함께 차세대 전력망인 '스마트 그리드'가 대두되고 있다. 이에 따라 무선 센서들 간의 통신을 위해 IEEE 802.15.4 표준 기술이 채택되고 있다. IEEE 802.15.4 표준에는 beacon-enabled mode 와 non beacon-enabled mode 두 가지 채널 접근 기법이 존재하지만 특정 기법의 용도와 목적에 대해서는 구체적으로 명시되지 않는다. 따라서 본 논문에서는 스마트 그리드 환경에서 IEEE 802.15.4 의 두 채널 접근 기법의 성능을 시험하고 beacon-enabled mode 와 non beacon-enabled mode 간의 성능 분석을 통해 beacon-enabled mode 의 효용성에 대하여 연구한다.

• International Journal of Highway Engineering
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• v.7 no.4 s.26
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• pp.113-123
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• 2005

In this study, calcium chloride$(CaCl_2)$, sodium chloride (NaCl), organic acids-containing deicer(NS 40, NS 100), mixed deicier$(NaCl\;70%+CaCl_2\;30%,\;NS\;40\;70%+CaCl_2\;30%,\;NaCl\;70%+NS\;40\;30%,\;NS\;40\;70%+NaCl\;30%)$ is investigated based on the laboratory test for deicing performance, freez-thaw resistance of concrete, and corrosion rate of metal. Test items for deicing performance were ice melting and ice penetration, freezing point depressions and eutectic point, pH, thermal properties for selected deicing chemicals as well as their compatibility with concrete and metal were experimentally investigated. As a test results, in case of the use chloride-containing deicier in area that concrete structures has subjected to freez-thaw reaction in winter season, it showed that mixed deicing chemicals with optimum ratio has desirable method than use one deicing chemicals when is consider to deicing performance and effects, corrosion of steel materials, and freez-thaw resistance of concrete. When use various deicing chemicals mixed, NS40(70%)+calcium chloride(30%) showed the best effective method.

• BMB Reports
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• v.38 no.2
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• pp.151-160
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• 2005

By a cDNA array representing 2308 signal transduction related genes, we studied the expression profiles of HeLa cells stably transfected by Hepatitis C virus nonstructural protein 4B (HCV-NS4B). The alterations of the expression of four genes were confirmed by real-time quantitative RT-PCR; and the aldo-keto reductase family 1, member C1 (AKR1C1) enzyme activity was detected in HCV-NS4B transiently transfected HeLa cells and Huh-7, a human hepatoma cell line. Of the 2,308 genes we examined, 34 were up-regulated and 56 were down-regulated. These 90 genes involved oncogenes, tumor suppressors, cell receptors, complements, adhesions, transcription and translation, cytoskeletion and cellular stress. The expression profiling suggested that multiple regulatory pathways were affected by HCV-NS4B directly or indirectly. And since these genes are related to carcinogenesis, host defense system and cell homeostatic mechanism, we can conclude that HCV-NS4B could play some important roles in the pathogenesis mechanism of HCV.

• Journal of Life Science
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• v.29 no.4
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• pp.436-441
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• 2019

Nelumbo nucifera, also known as sacred lotus, has mainly been used as a food throughout the Asian countries. In the present study, we prepared ethanol extracts from leaf (NL), seed (NS), and seedpod (NSP) of Nelumbo nucifera and investigated their anti-inflammatory activities in mouse macrophage RAW 264.7 cells. To evaluate the anti-inflammatory activities of NL, NS, and NSP, nitric oxide (NO) production was measured in LPS-stimulated RAW 264.7 cells. NL, NS, and NSP significantly reduced NO production in a dose-dependent manner without affecting cell viabilities. NL, NS, and NSP dramatically decreased the protein expression of pro-inflammatory genes such as iNOS and COX-2. NL, NS, and NSP also suppressed phosphorylation of MAPKs and the nuclear translocation of $NF-{\kappa}B$ p65 indicating they have their anti-inflammatory activities via regulating mitogen-activated protein kinases (MAPKs) and nuclear factor kappa B ($NF-{\kappa}B$) pathways. In addition, we analyzed the production of reactive oxygen species (ROS) by the treatment of NL, NS, and NSP. All extracts reduced ROS production in a dose-dependent manner. And also, they increased heme oxygenase-1 (HO-1) protein expression and the nuclear translocation of nuclear respiratory factor 2 (Nrf2). In conclusion, our results suggest that Nelumbo nucifera has its anti-inflammatory activity via regulating MAPKs, $NF-{\kappa}B$, and Nrf2/HO-1 pathways.

• Animal Bioscience
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• v.34 no.4
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• pp.734-742
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• 2021

Objective: The present study aimed to investigate the occurrence and species of coagulase-positive staphylococci (CoPS) and coagulase-negative staphylococci (CoNS) in retail pork meat samples collected during nationwide monitoring. The staphylococcal isolates were characterized for antimicrobial and zinc chloride resistance and enterotoxigenic potential. Methods: A total of 260 pre-packaged pork meat samples were collected from 35 retail markets in 8 provinces in Korea for isolation of staphylococci. Antimicrobial and zinc chloride resistance phenotypes, and genes associated with the resistance phenotypes were determined on the isolates. Furthermore, the presence and distribution of 19 staphylococcal enterotoxin (SE) genes and enterotoxin-like genes among the pork-associated staphylococci were determined by multiplex polymerase chain reaction-based assays using the specific primer sets. Results: A total of 29 staphylococcal strains (29/260, 11.1%) were isolated from samples of retail pork meat, 24 (83%) of which were CoNS. The four CoNS species identified were S. saprophyticus (n = 16, 55%), S. sciuri (n = 3, 10%), S. warneri (n = 3, 10%), and S. epidermidis (n = 2, 7%). Among the 29 isolates, four methicillin-resistant CoNS (MR-CoNS; three S. sciuri and one S. epidermidis) and one methicillin-resistant CoPS (MR-CoPS; one S. aureus) were identified. In addition, a relatively high level of tetracycline (TET) resistance (52%) was confirmed in CoNS, along with a predominant distribution of tet(K). The most prevalent SEs were sep (45%), and sen (28%), which were carried by 81% of S. saprophyticus. Conclusion: These findings suggest that CoNS, especially S. saprophyticus strains, in raw pork meat could be a potential risk factor for staphylococcal food poisoning (SFP), and therefore, requires further investigation to elucidate the role of SEls in SFP and virulence of the pathogen. Our results also suggest that CoNS from raw pork meat may act as a source for transmission of antimicrobial resistance genes such as staphylococcal cassette chromosome mec and tet(K).

• Journal of Microbiology
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• v.33 no.3
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• pp.260-266
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• 1995

Hepatitis C virus (HCV) has been considered as a mojor causative agent of post-transfusion related non-A, non-B hepatitis. In this study, the cDNA sequence of NS4 region of HCV (HCV-S) obtained from a Korean patient's plasms was determined. Comparative nucleotide sequence analysis between to type II. 67.2% homology to type III, and 66.4% homology to type IV. The putative amino acid sequence homologies to types I, II, III, and IV were 82.8-84.7%, 92.5-95.1%. 72.5, and 71.1%, respectively. This data strongly suggests that HCV-S should be classified as type II. Significant similarities of hydrophobicity profiles and putative transmembranous domains were found in HCV-S and four major prototypes, indicating that the protein structure is similar in spite of the heterogeneities of intertype homologies at the level of the psrimary nucleotide and amino acid sequences.

• Journal of Positioning, Navigation, and Timing
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• v.9 no.4
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• pp.347-356
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• 2020

In this study, Inclined Geosynchronous Orbit (IGSO) and Geostationary Orbit (GEO) of BeiDou System (BDS) and Quasi Zenith Satellite System (QZSS) satellites positions and clock errors calculated by broadcast ephemeris and compared with Multi-GNSS Experiment (MGEX) products provided by five Analysis Centers (ACs). Root Mean Square Errors (RMSE) calculated for satellite position error. The IGSO results showed that 1.82 m, 0.91 m, 1.28 m in BDS and 1.34 m 0.36 m 0.49 m in QZSS and the GEO results showed that 2.85 m, 6.34 m, 6.42 m in BDS and 0.47 m, 4.79 m, 5.82 m in QZSS in the direction of radial, along-track and cross-track respectively. RMS calculated for satellite clock error. The IGSO result showed that 2.08 ns and 1.24 ns and the GEO result showed that 1.28 ns and 1.12 ns in BDS and QZSS respectively.

• Journal of Pharmacopuncture
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• v.4 no.1
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• pp.103-104
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• 2001

This study was done to observe the effect on the local thermal changes of herbal acupuncture on D.I.T.I.. The objects of this study are as follows; If there are remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I.or not. If there are those, We examine how long that changes are maintained, what the adequate interval is on herbal acupuncture therapy, and what the reaction in a .local or whole body are on that therapy Materials and Methods : To study the local thermal changes in herbal acupuncture therapy, D.I.T.I. was used. Determination of this analysis periods are pre and post-therapy(1 hour, 24hours, 48hours and 7days later). The study group was divided into three groups(comprised 23 students in oriental medical college, Woosuk University). One was NS(Normal Saline) group, another was CF(CARTHAMI SEMEN) group and the other was BU(FEL URSI + BENZOAR BOVIS) group. The Herbal Acupunture solution was injected 0.2ml divide into 0.05ml at tile P'ungmun(B12), P'yesu(B13), Pubun(B41), Paek'o(B42) 4 points. Then, in order to analyze the clinical form, we have observed response of 23 students whenever we checked the thermal changes of their after perfoming Results : The results were obtained as follows ; 1. There is no significant dermatothermal changes at NS group and CF group, but BU group have remarkable changes in 24, 48, 72 hours. 2. From post-therapy 1 hour to 48 hours, there is a significant change (P<0.01) at NS-BU group and CF-BU group, But there is none 7 days later. 3. In the analysis of whole or local body reaction, local pain appears at NS group(22%), CF group(11%), BU group(91%), discomfort reaction appears at CF group(14%), BU group(30%). BU groilp has feel vertigo(13%), drowsy (70%) and pain in action(52%). 4. In the analysis of the duration of physic진 reaction, BU group is most lately maintained. Conclusions : These results suggest that in the physical reaction of herbal acupuncture solutions, BU solution is more sensitive than CF solution or NS.