• Korean Journal of Psychosomatic Medicine
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• v.27 no.2
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• pp.155-163
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• 2019

Objectives : The aim of this study was to compare severity, neurocognitive functions, and behavioral and psychological symptoms of dementia (BPSD) according to the degree of temporal lobe atrophy (MTA) in Korean patients with dementia due to Alzheimer's disease and mild cognitive impairment due to Alzheimer's disease. Methods : Participants were 114 elderly subjects diagnosed with Alzheimer's disease or mild cognitive impairment in this cross-sectional study. MTA in brain MRI was rated with standardized visual rating scales (Scheltens scale) and the subjects were divided into two groups according to Scheltens scale. Severity was evaluated with Clinical Dementia Rating (CDR) and Global Deterioration Scale (GDS). Neurocognitive functions was evaluated with the Korean version of Short Blessed Test (SBT-K) and the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease assessment packet (CERAD-K). BPSD was evaluated with the Korean version of the Neuropsychiatric Inventory (K-NPI). Independent t-test was performed to compare severity, neurocognitive functions, and BPSD between two groups. Results : The group with high severity of MTA showed significantly lower scores in CDR, SBT-K, MMSE-KC, modified Boston naming test, word list recognition, and word list memory (p<0.05). There were no differences in K-NPI scores between two groups. Conclusions : Severity and neurocognitive functions of dementia had significant positive association with MTA, but BPSD had no association with MTA. Evaluating MTA seems to have potential benefit in diagnosing and treating neurocognitive impairments in the elderly. Further evaluation is needed to confirm the association between certain brain structures and BPSD.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.459-469
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• 2016

The purpose of this study was to examine different patterns of behavioral and psychological symptoms of dementia (BPSD) and caregiver burden according to dementia type. Data were collected from June 2014 to December 2014 from five nursing homes. In all, 214 patients [131 patients with Alzheimer's disease (AD) and 83 patients with Vascular dementia (VD)] were included in the study. BPSD and caregiver burden data were examined using NPI-NH (Neuropsychiatric Inventory Nursing Home Version). According to the results, both the AD and VD group showed the highest frequency in apathy/indifference and the frequency of anxiety, elation/euphoria, and irritability/lability was significantly higher in the AD group than in the VD group. The difference in total BPSD composite scores between the AD and VD groups was not significant but agitation/aggression was significantly higher in the AD group than in the VD group. The mean score for caregiver burden was significantly higher in the AD group than in the VD group, particularly in agitation/aggression. In conclusion, BPSD differed according to dementia type, and nurses should provide specific interventions to control BPSD; a program to reduce caregiver burden according to dementia type is also needed.

• Korean Journal of Culture and Social Issue
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• v.21 no.3
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• pp.377-394
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• 2015

The purpose of this research was to identify the relationship between specific personality characteristics and maladaptive social behaviors in order to contribute to development of a pragmatic intervention for the prevention of sexual aggression. This was accomplished by examining the mediating effects of entitlement rage (K-PNI) or sociosexuality (K-MSAS) on sexual aggression, and moderating effects of cognitive emotion regulation strategies (K-CERQ) or state empathy (K-CMEM) on sexual aggression in narcissistic men. Data were obtained from male college students (n = 264) who completed self-report questionnaires, such as K-NPI and K-CMEM, and hierarchical regression analysis was applied to examine these relationships. Both entitlement rage and cognitive emotion regulation strategies were found to be unassociated with sexual aggression. Rather, sociosexuality was the mediating factor between narcissism and sexual aggression, Whereas state empathy was a moderating factor between narcissism and sexual aggression. These findings indicate a tendency for sociosexuality to increase sexual aggression in males. However, individuals with low state empathy are more likely to show sexual aggression than those with high state empathy, indicating that intervention for increased state empathy may be a more effective treatment than cognitive emotion regulation strategies.

• Journal of Korean geriatric psychiatry
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• v.16 no.1
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• pp.24-30
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• 2012

Objectives : The purpose of this study was to compare the efficacy of galantamine treatment, especially attention ability between patients with pure Alzheimer's disease (AD) and Mixed dementia (MD) during a 24-week trial. Methods : A total of 40 patients were recruited for this 24-week study. The effect of galantamine on attention was measured using Seoul Computerized NeuroCognitive Function Test (SCNT) and frontal functions test of Seoul Neuropsychological Screening Battery (SNSB). Patients'activities of daily living using the Seoul-Activities of Daily Living (S-ADL) and the Seoul-Instrumental Activities of Daily Living (S-IADL) ; behavioral symptoms using the Korean version Neuropsychiatric Inventory (K-NPI) were measured at baseline and 24-week. Results : 17 pure AD patients and 23 MD patients were analyzed in this study. Attention as measured by SCNT was not significantly different from baseline after 24 weeks of treatment in both groups. There was no significant difference between two groups in mean change from baseline in the SCNT, S-ADL, S-IADL and K-NPI scores at 24-week. Conclusion : Galantamine showed a therapeutic effect on cognition, activities of daily living, neuropsychiatric symptoms in pure AD and MD. Furthermore, Galantamine may specifically help to maintain attention and it may have positive effects on other cognitive and functional abilities.

• The Korean Journal of Health Service Management
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• v.9 no.3
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• pp.255-266
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• 2015

Objective : The aim of this study was to examine the effects of the Home-based Multi-component Activity Program (Home-MAP) for the maintenance activities of daily living (ADL) for patients with mild Alzheimer's disease (AD) and on caregiver burden for caregivers. Methods : Nine mild AD patients and family caregivers. The Home-MAP was performed 1d/wk, for a total of 10 times over 10 weeks. Results : After the 10 sessions, participants' motor and process skills scores on the AMPS were found to have significantly improved (p=.028 and p=.028, respectively). The BPSD frequency score on the R-MBPC was found to be significantly reduced (p=.017). The BPSD symptoms related to caregiver reaction score on the R-MBPC and distress score on the NPI-Q were significantly reduced (p=.039 and p=.018, respectively). Conclusions : The Home-MAP appears to have contributed to the improvement of patients' capabilities in performing in ADL, to a reduction of BPSD, and to a reduction of burden related to BPSD.

• Journal of the Korean Society of Physical Medicine
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• v.7 no.1
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• pp.37-47
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• 2012

Purpose : The purpose of this study is to examine the effects of training in exercise rehabilitation on depressive emotion, behavioral and psychological symptoms(BPSD) caused by Alzheimer's disease elders. Methods : The subjects of this study were 34 patients with Alzheimer's disease over 65 and assigned randomly into one of two groups, each with 17 people. The experimental group was treated by training in exercise rehabilitation executed 60 minutes, 3 times a week for 8 weeks. The results of the experiment were analyzed using samples t-test along with averages and standard deviations as the statistical methods for data analyses. Results : The results of this study were as follows. First, the experimental group showed statistically significant improvements in the areas of depressive emotion(SGDS) compared to control group. Second, the experimental group showed statistically significant improvements in the severity of behavioral and psychological symptoms and subjective degrees of pain of care givers(NPI-Q) compared to control group. Conclusion : Based on the results of this study, training in exercise rehabilitation have an effect on depressive mood and BPSD in elderly with Alzheimer's disease.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.126-130
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• 1997

In the development of the totally implantable artificial heart (TAH), the information of the preload condition is important to ind appropriate condition or the automatic control of the heart. Our TAH configuration consists of two artificial ventricles, and brushless DC motor within actuator. The pressure between ventricles could indicate the preload condition during the TAH operation. If we can measure accurately inspite of the noise induced from TAH and environmental condition. We suggested integrating a feedback loop to remove an unexpected DC drift. NPI 19-series Nova sensor was used which could measure pressure in gas and liquid. This method and sensor enabled us to develop the pressure transducer compact so (that) the systems can be implanted with TAH into patient. This system has been verified in vitro and in vivo test. This results showed that the output waveform of this system was stable irrespective of animal condition.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2006.06b
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• pp.325-329
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• 2006

Nippon Paper Industries, Co., Ltd. declared conversion of all the bleaching process to ECF, and most of the production had converted by now. To reduce ECF bleaching cost, we found that depending on electricity supply condition of the mill, utilization of ozone bleaching could be very effective. In addition, hot acid treatment of unbleached pulp also seemed to be effective for hardwood. In this study, several conditions for each technology were examined with the pulps from our own mills to reduce bleaching cost and to keep fiber quality acceptable level. In hot acid treatment study, with mild conditions (temperature lower than $90^{\circ}C$), sufficient reduction in Kappa number and hexenuronic acids content of the pulp were observed, while pulp viscosity was maintained. Moreover, to maintain strength of bleached pulp that subjected both to ozone bleaching and hot acid treatment, recommended Kappa number after ozone bleaching was more than 3. Based on these findings, two of our mills had installed medium-consistency ozone bleaching facilities and three mills installed hot acid treatment. Especially in Yatsushiro mill, both were installed in one bleaching line (A-ZD-E/P-D sequence), and running successfully.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5595-5600
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• 2012

This paper is to review and study about the crystallization nucleating agent to improve the heat-resistance properties of poly(lactic acid). Four sub-micron sized nucleating agents, metallic salts of 2,2'-methylene bis(4,6-di-tert-butylphenol), were prepared and used as a crystallization nucleating agent. Thermal and mechanical properties of polymer compounds were investigated by DSC, HDT and UTM. As the results, While the heat-resistance properties of the polymer compound samples were increased linearly with the contents of nucleating agent as well as their smaller size. Among them, the highest heat-resistance property of compound was observed with 2 wt% of MPZ2. HDT values of PL98Z2 compound was $116^{\circ}C$ at 0.455Mpa.

• Child Health Nursing Research
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• v.1 no.1
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• pp.5-15
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• 1995

The quality of mother-infant interaction during early postpartum period has a significant influence on the child growth and development in many aspects. The mother's initial perception of the newborns might have the lasting influence on the development of the mother-infant attachment and mother-infant relationship. Therefore the proper mother-infant interaction should be developed after infant birth. However, it is acknowledged that the high risk infants influence on the mothers' perception because of their abnormalities or disorders of physical condition and the restricted maternal contacts and interactions. The object of this study is to identify the difference of mother's perception of their normal and high-risk newborn during the early postpartum period. The ultimate goal is to contribute to use this basic data to develop nursing intervention toward the promotion of healthy mother-infant relationship and the helping of growth and development of children. The data were collected for this study from Sep. 21, 1990 to Oct. 1. 1991 at E University Hospital. The sample was 83 of mothers who had normal newborns and 73 mothers who had high risk newborns .The instrument was Neonatal Perception Inventory(NPI) designed by the Broussard for the measurement of mothers' perception of newborns about Average Baby and Your Baby. The data were analysed by using an SPSS Program and include percentage mean, SD, t-test, ANOVA. The results of this study are as follows : 1. The normal newborn mothers' perception is more positive than the high-risk newborn mothers(t=7.94, p=0.000). 2. Mothers' perception of the newborns is not related significantly to mothers' general characteristics. In conclusion, in order to promote positive, healthy mother-infant relationship, the nurse need to support, give information, and educate high-risk newborn mothers through early nursing assessment.