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Accuracy of maximal expiratory flow-volume curve curvilinearity and fractional exhaled nitric oxide for detection of children with atopic asthma

  • Park, Sang Hoo;Im, Min Ji;Eom, Sang-Yong;Hahn, Youn-Soo
    • Clinical and Experimental Pediatrics
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    • 제60권9호
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    • pp.290-295
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    • 2017
  • Purpose: Airway pathology in children with atopic asthma can be reflected by the concave shape of the maximal expiratory flow-volume (MEFV) curve and high fractional exhaled nitric oxide (FeNO) values. We evaluated the capacity of the curvilinearity of the MEFV curve, FeNO, and their combination to distinguish subjects with atopic asthma from healthy individuals. Methods: FeNO and angle ${\beta}$, which characterizes the general configuration of the MEFV curve, were determined in 119 steroid-naïve individuals with atopic asthma aged 8 to 16 years, and in 92 age-matched healthy controls. Receiver operating characteristic (ROC) curve analyses were performed to determine the cutoff points of FeNO and angle ${\beta}$ that provided the best combination of sensitivity and specificity for asthma detection. Results: Asthmatic patients had a significantly smaller angle ${\beta}$ and higher FeNO compared with healthy controls (both, P<0.001). For asthma detection, the best cutoff values of angle ${\beta}$ and FeNO were observed at $189.3^{\circ}$ and 22 parts per billion, respectively. The area under the ROC curve for the combination of angle ${\beta}$ and FeNO improved to 0.91 (95% confidence interval [CI], 0.87-0.95) from 0.80 (95% CI, 0.75-0.86; P<0.001) for angle ${\beta}$ alone and 0.86 (95% CI, 0.82-0.91; P=0.002) for FeNO alone. In addition, the combination enhanced sensitivity with no significant decrease in specificity. Conclusion: These data suggest that the combined use of the curvilinearity of the MEFV curve and FeNO is a useful tool to differentiate between children with and without atopic asthma.

수동형 전자발신장치(Passive Integrated Transponder, PIT) 모니터링 기법 적용에 따른 어종별 생존율 평가 및 어도에서 어류이동성 평가 (The Evaluations of Fish Survival Rate and Fish Movements using the Tagging Monitoring Approach of Passive Integrated Transponders (PIT))

  • 최지웅;안광국
    • 한국환경과학회지
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    • 제23권8호
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    • pp.1495-1505
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    • 2014
  • The objective of this study was to evaluate survival rate and fish movement (migration) using a tagging approach of passive integrated transponder (PIT) in Juksan Weir, which was constructed as a four major river restoration projects. For this study, survival rates of each fish species and the mobility of fish individuals were analyzed during 2 weeks by the insertion of PIT tags to various fish species in the laboratory. According to tagging tests in the laboratory, the survival rate 37.5% (30 survivals of 80 individuals) after the insertion of PIT tags. The survival rate of Carassius auratus and Hemibarbus labeo was 100% and 80% after the insertion of the tags, respectively, whereas it was only 13.3% for Zacco platypus. In the field experiments of Juksan Weir, 6 species and 157 individuals from 8 species (563 individuals) were detected in the fixed automatic data-logging system, indicating a detection rate of 27.9% in the fishway of Juksan Weir. In the meantime, some species with no or low detection rates in the fixed automatic data-logging system were turn out to be stagnant-type species, which prefer stagnant or standing water to live.

한국성인 정상교합자에서 Delaire의 이상적 교합평면과 저작근 근활성도와의 관계에 대한 연구 (A STUDY ON THE RELATION BETWEEN DELAIRE'S IDEAL OCCLUSAL PLANE AND MASTICATORY MUSCLE ACTIVITY IN KOREAN NORMAL ANGLE CLASS I OCCLUSION INDIVIDUALS)

  • 변성규;이충국
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제26권3호
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    • pp.229-237
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    • 2000
  • According to the functional matrix theory, Delaire proposes that individual occlusal plane was determined by variable effects of teeth, maxilla, mandible, cranium, cranial base and soft tissue matrix including the orofacial musculature. and that there is the ideal occlusal plane determined by the most proper spatial position of maxilla and mandible, functionally and esthetically. This study was designed to find out the relation between Delaire's ideal occlusal plane and muscle activity of masticatory muscles in individuals who have normal maxillo-mandibular relationships. Lateral cephalometric radiographs were taken and his/her individual occlusal plane and ideal occlusal plane were analyzed with Delaire's architectural and structural craniofacial analytic method. For evaluation of muscle activities of masticatory muscles, electromyography of anterior temporal muscle, superficial masseter muscle, and anterior belly of digastric muscle was recorded in fifty Korean normal Angle class I occlusion individuals. According to the average value of ideal occlusal plane, fifty normal Angle class I occlusion individuals were classified into three groups: Ideal occlusal plane group(I group), hyperrotation group(I+ group) and hyporotation group(I- group). The result of this study was as follows: 1. The results of Delaire's architectural and structural craniofacial analysis of lateral cephalography of the fifty Korean normal Angle class I occlusion individuals are that twelve persons(24%) have consistent or parallel with ideal occlusal plane and the average of angular difference was $1.22^{\circ}{\pm}3.69^{\circ}$. 2. There is no significant difference in muscle activities of masticatory muscles during resting(p<0.05), but significant increases of muscle activity of ipsilateral anterior temporal and masseter muscle, contralateral anterior belly of digastric muscle during unilateral chewing and of anterior temporal and masseter muscle during bilateral clenching(p<0.05). 3. To find out the effect of the angular difference between Delaire's ideal occlusal plane and real occlusal plane to muscle activity, muscle activities of masticatory muscles were compared with three groups in each other; I group, I+ group and I- group. The results were no significant differences during resting, unilateral chewing and bilateral clenching.(p>0.05) 4. Although there is no significant differences of masticatory muscle activities among the three groups, the fact that increasing tendency of masseter muscle activity of ideal occlusal plane group(I+) than those of any other groups(I+ and I-) during bilateral clenching was noted. There is only the implication that occlusal plane makes some effects on masticatory muscle activities, espacially that of masseter muscle during bilateral clenching. In conclusion, the hypothesis that occlusal plane is one of the factors which affect the muscle activities of masticatory muscles and that anyone whose occlusal plane consistent with Delaire's ideal occlusal plane has an extraordinary functional advantage in masticatory muscle function cannot be proven with electromyography methods.

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부영양 저수지에서 국내 담수산 패류가 수질에 미치는 영향 (Effects of Domestic Freshwater Shellfishes on the Water Quality in the Eutrophic Agricultral Reservoir)

  • 황순진;박구성;백순기;김백호
    • 한국물환경학회지
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    • 제26권1호
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    • pp.148-155
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    • 2010
  • Water quality and plankton community dynamics after the introduction of two domestic freshwater shellfishes (Unio douglasiae Griffith & Pidgeon and Cipangoplaudina chinese malleata Reeve), were monitored daily in enclosures, which constructed in the tidal zone of eutrophic agricultural reservoir (Shingu reservoir, Korea) for one week between July 31 and August 6, 2007. This biomanipulation study to improve the water quality of eutrophic lake, comprised eight enclosures (duplicate x four kinds), enclosure had no mussels (Control), stocked only with U. douglasiae at density of 60 individuals (UD), stocked only with C. chinese malleata at density of 60 individuals (CCM), and combined-stocked with 30 individuals of UD and 30 individuals of CCM (MIX), respectively. Our results clearly indicate that UD strongly decreased the concentration of chlorophyll-a and increased the water transparency, whereas CCM and MIX (included CCM) did increase algal density or decrease transparency, due perhaps to the disturbance of C. chinese malleata. Therefore, the field application of shellfish to enhance the water quality of eutrophic agricultural reservoir, should consider the grazing characteristics of biological control agents, especially active moving animals like snail.

지역사회 뇌졸중 환자를 위한 순환식 집단 운동프로그램의 효과 (Effect of a Weekly Circuit-Group Exercise Program on Community-Living Individuals With Chronic Stroke)

  • 김선엽;오덕원
    • 한국전문물리치료학회지
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    • 제15권3호
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    • pp.17-25
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    • 2008
  • This study aimed to evaluate the effect of a weekly circuit-group exercise program on functional performance, flexibility of the trunk and lower extremities, and balance in individuals with chronic stroke who are living in a community. Thirteen community-living individuals (eleven males and two females) with chronic stroke participated in this study. The group exercise program was set up as a weekly circuit application with four stations aiming to strengthen the muscles, increase endurance, improve flexibility, and enhance functional capacity. The average duration of a session was an hour, and the sessions were conducted once a week for six months for a total of 24 sessions. Assessments for functional performance, flexibility of the trunk and lower extremities and balance were conducted four times: before treatment, after one month of treatment, after four months of treatment, and after six months of treatment. There were significant improvements in functional performance and flexibility of the trunk and lower extremities in the given time frame. No significant improvement was observed in balance ability. The findings suggest that a weekly circuit-group exercise program has some benefits in terms of managing the physical symptoms of individuals with mobility problems after stroke. Therefore, this program can be adapted and employed as a community-based rehabilitation program for such patients. Further studies with various community-based treatments will be conducted to validate these findings.

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Physical Activities and Health-related Quality of Life of Individuals Post Stroke

  • Choi, Young-eun;Kim, Ji-hye
    • 대한물리의학회지
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    • 제10권2호
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    • pp.47-54
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    • 2015
  • PURPOSE: The purpose of this study is to examine the relationship between the physical activities of individuals post-stroke and their HRQL, as well as to determine whether their functional abilities contribute to their amounts of physical activity. METHODS: The study's subjects included 90 individuals post-stroke. Their amounts of physical activity were measured using the International Physical Activity Questionnaire (IPAQ), and their HRQL was measured using the Medical Outcomes Study 36-Item Short-form Health Survey (SF-36). In addition, the functional abilities of the subjects were measured. For the measures of physical activities and the HRQL, Pearson's correlation coefficients were used to identify the strengths of the associations between the measures. A hierarchical linear regression model was used to determine whether physical activities had independent impacts on the HRQL. RESULTS: This study found that the physical activities performed by the subjects affected the SF-36 physical component score (PCS) (12%). However, the physical activities and the SF-36 mental component score (MCS) showed no statistically significant relationship, whereas functional abilities and physical activities had a statistically significant relationship (r = .57~.86, p<.001). CONCLUSION: The present study identified a correlation between physical activity and the PCS. Therefore, individuals post-stroke should be encouraged to carry out more physical activities, including more frequent walking activities.

한국 남해 연안 갯장어(Muraenesox cinereus)의 생태학적 특성 및 식품 성분 비교 (Ecological Characteristics and Proximate Composition of Muraenesox cinereus off the Southern Coast of Korea)

  • 고은혜;권대현;남기호;김영혜;장충식
    • 한국수산과학회지
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    • 제52권2호
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    • pp.173-179
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    • 2019
  • We investigated the ecological characteristics and proximate composition of Muraenesox cinereus off the southern coast of Korea. Anal length distribution, sex ratio, condition factor of M. cinereus individuals caught by costal complex (longline) fisheries were investigated from June to October 2018. The mean anal length was 23.5 cm, which was less than $L_{50}$, indicating that the individuals were mostly immature. Sex ratio is 9:1, we captured 382 females and 29 males, which produced a significantly different ratio (P<0.05). Condition factor remained constant over the study period. The proximate composition of M. cinereus individuals was analyzed from July to October 2018. No significant differences in moisture, crude lipid, crude protein, and ash content were observed between individuals caught in summer and those caught in fall.

The effect of aromatherapy on pain in individuals with diabetes: a systematic review and meta-analysis

  • Mi-Kyoung Cho;Mi Young Kim
    • Journal of Korean Biological Nursing Science
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    • 제26권2호
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    • pp.71-82
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    • 2024
  • Purpose: This study systematically analyzed the impact of aromatherapy on pain in individuals with diabetes. Methods: A search was performed in seven electronic databases based on the PICO-SD (Population, Intervention, Comparison, Outcome, Study Design) framework. The population (P) of interest was individuals with diabetes, and the intervention (I) included aromatherapy targeting pain reduction. The comparison (C) consisted of control groups that received no intervention, another intervention, or usual care. The outcome (O) measured was pain. The quality of the selected literature was assessed using the Joanna Briggs Institute checklist. In MIX 2.0 Pro, the pooled overall effect of pain was calculated using Hedge's g and a random-effects model, and heterogeneity was calculated using the Q statistic and Higgin's I2 values. Meta-regression and exclusion sensitivity analyses were performed. Results: Five articles and seven studies were included, showing a significant pooled overall effect of aromatherapy on diabetes-related pain (Hedge's g = -1.83, 95% CI: -2.76 to -0.91). Meta-regression demonstrated that effectiveness in reducing pain was associated with studies conducted in West Asia, those with IRB approval, and those receiving funding. Additionally, interventions involving subjects under 60, lavender oil (vs. turpentine oil or blended oils), massage therapy (vs. topical application), fewer hours per session, and more repeated measurements (vs. pre/post measurements) were associated with pain reduction. Conclusion: Aromatherapy, especially with lavender oil, effectively manages diabetes-related pain. Short-duration massage application is also effective. A personalized selection of oil type and application method could optimize therapeutic outcomes for individuals with diabetes.

The Investigation into the Relationship between Intellectual Preferences Model and Preparation for Organization

  • Yami, Masoud Movafagh;Asgari, Omid
    • Asian Journal of Business Environment
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    • 제7권3호
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    • pp.5-15
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    • 2017
  • Purpose - The objective of the present study is to examine the relationship between intellectual preferences of individuals and the level of readiness for change according to Ned Herman. Research design, data and methodology - For this, Iranian Supreme Audit Court was selected as a case study in this research and it was carried out to evaluate research variables and test hypotheses using standard questionnaires of intellectual preferences and readiness for change based on the methodology. It should be remarked that only 32 managers of Audit Court were willing to participate in this research and responded to the questionnaires. Results - The outputs of the performed tests showed that although there is not a significant relationship between the individuals with intellectual preferences for class A and readiness for change them, approaching the intellectual preferences of the individuals to D region increases the readiness for change them. On the other hand, whatever individuals have intellectual preferences for branches in groups B and C, the level of preparedness for change is low. Conclusions - The results of this research have made a clear policy for the effective utilization in human resources based on their intellectual preferences model for management with organizational changes.

Association of daily carbohydrate intake with intermuscular adipose tissue in Korean individuals with obesity: a cross-sectional study

  • Ha-Neul Choi;Young-Seol Kim;Jung-Eun Yim
    • Nutrition Research and Practice
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    • 제18권1호
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    • pp.78-87
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    • 2024
  • BACKGROUND/OBJECTIVES: The prevalence of obesity, a worldwide pandemic, has been increasing steadily in Korea. Reports have shown that increased intermuscular adipose tissue (IMAT) is associated with an increased risk of cardiovascular disease, independent of body mass index. However, the relationship between dietary intake and IMAT accumulation in the Korean population remains undetermined. The objective of this study was to evaluate regional fat compartments using advanced magnetic resonance imaging (MRI) techniques. We also aimed to investigate the association between IMAT amounts and dietary intake, including carbohydrate intake, among Korean individuals with obesity. SUBJECTS/METHODS: This cross-sectional study, performed at a medical center in South Korea, recruited 35 individuals with obesity (15 men and 20 women) and classified them into 2 groups according to sex. Anthropometry was performed, and body fat distribution was measured using MRI. Blood parameters, including glucose and lipid profiles, were analyzed using commercial kits. Linear regression analysis was used to test whether the IMAT was associated with daily carbohydrate intake. RESULTS: Carbohydrate intake was positively associated with IMAT in all individuals, with adjustments for age, sex, height, and weight. No significant differences in blood indicators were found between the sexes. CONCLUSIONS: Regardless of sex and age, higher carbohydrate intake was strongly correlated with greater IMAT accumulation. This suggests the need to better understand sex differences and high carbohydrate diet patterns in relation to the association between obesity and metabolic risk, which may help reduce obesity prevalence.