• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.2111-2111
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• 2001

A chemoinfometrical method for evaluating the quantitative determination of crystallinity one polymorphs based on fourie-transformed near-infrared (FT-NIR) spectroscopy was established. A direct comparison of the data with the ones collected from using the and compared with the conventional powder X-ray diffraction method was performed. [Method] The pPure a and g forms of indomethacin (IMC) were prepared by reportedusing published methods. Six kinds of standard samples obtained by physically mixing of a and g forms. After the powder X-ray diffraction profiles of samples have been measured, the intensity values were normalized to against the intensity of silicon powder as the as an external standard. The calibration curves for quantification of crystal content were based upon the total relative intensity of four diffraction peaks from of the form g crystal. FT-NIR spectra of six calibration sample sets were recorded 5 times with the NIR spectrometer (BRAN+LUEBBE). Chemoinfometric analysis was performed on the NIR spectral data sets by applying the principal component regression (PCR). [Results] The relation between the actual and predicted polymorphic contents of form g IMC measured using by the X-ray diffraction method shows a good straight linen linear relation., and it has slope of 0.023, an intercept of 0.131 and a correlation coefficient of 0.986. PCR analyses wereis was performed based on normalized NIR spectra sets offer standard samples of known content of IMC g form. IMC. A calibration equation was determined to minimize the root mean square error of the predictionthe prediction. Figure 1 shows a plot of the calibration data obtained by NIR method between the actual and predicted contents of form g IMC. The predicted values were reproducible and had a smaller standard deviation. Figure 2 shows that the plot for the predicted transformation rate (%) of form a IMC to form g as measured by X-ray diffractomeoy against to those as measured by NIR method. The plot has a slope of 1.296, an intercept of 1,109, and a correlation coefficient of 0.992. The line represents a satisfactory correlation between the two predicted values of form g IMC content. Thus NIR spectroscopy is an effective method for the evaluation to the pharmaceutical products of quantitative of polymorph.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1052-1052
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• 2001

Hear infrared (NIR) spectra were measured, at five temperatures, for forty-eight samples of honey, from a variety of geographical and botanical sources, and the data has been used to explore the possibility of using NIR spectroscopy for testing label claims concerning the geographical and botanical source of honey being offered for sale to the public. These results demonstrate that the successful characterization of the botanical source of a honey may be obtained by NIR spectroscopy. Further work with large numbers of samples and groups will be required to realized this potential. Additional analysis of these data suggest that research into new ways of obtaining information on the change of absorption with temperature might be beneficial for a range of technologies.

• 펄프종이기술
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• 제39권5호
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• pp.58-63
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• 2007

This paper sums up all the different steps broached in this project : The NIR spectroscopy technique has been studied and implemented at CTP using a mobile spectrometer device and different optical materials. Methods, based on statistical data analysis (in particular PLS regressions), have been investigated. A laboratory "prototype" using these techniques and methods has been developed in order to control the recovered papers quality, in terms of humidity percentage and sample composition (paper, board, contaminants).

• Journal of Biosystems Engineering
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• 제31권5호
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• pp.395-402
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• 2006

Mixed heat transfer in an indirected NIR (Near Infrared Ray) dry chamber was investigated numerical analysis. It is Important that the miked heat transfer effects on double parameters which the Reynolds number and the position of emit lamp. Reynolds number are based on the outer diameter of the cylinder range from 103 to $30{\times}105$. Four difference heat transfer regimes of behavior are apparent: forced convection and radiation on the outer surface of the cylinder, pure conduction, pure natural convection and radiation between lamp surface and inner surface of the cylinder. The temperature and flow patterns are illustrated by iso-contour lines for the double parameters. Also presented are results on the convective heat transfer flux and the radiative heat transfer flux as increased with Reynolds number.

• 한국작물학회지
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• 제53권3호
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• pp.314-319
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• 2008

Near infrared (NIR) spectroscopy was used to classify normal and artificially aged nonviable corn (Zea mays L., cv. 'Suwon19') seeds. The spectra at 1100-2500nm were scanned with normal and artificially aged single seeds and analyzed by principle component analysis (PCA). To discriminate normal seeds from artificially aged seeds, a calibration modeling set was developed with a discriminant partial least square 2 (PLS 2) method. The calibration model derived from PLS 2 resulted in 100% classification accuracy of normal and artificially aged (aged) seeds from the raw, the 1st and 2nd derivative spectra. The prediction accuracy of the unknown normal seeds was 88, 100 and 97% from the raw, the $1^{st}$ and $2^{nd}$ derivative spectra, and that of the unknown aged seeds was 100% from all the raw, the $1^{st}$ and $2^{nd}$ derivative spectra, respectively. The results showed a possibility to separate corn seeds into viable and non-viable using NIR spectroscopy.

• 약학회지
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• 제48권3호
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• pp.177-181
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• 2004

Non-invasive blood glucose measurement from mouse tail was performed by near-infrared (NIR) spectroscopy. Three groups; normal, type I diabetes (insulin dependent diabetes mellitus, IDDM), type II diabetes (non-insulin dependent diabetes mellitus, NIDDM) group, were studied over a 10 weeks period with the collection of near-infrared (NIR) spectra. Spectral variations from long-term measurement (10 weeks) from dramatic and nonlinear changes in the optical properties of the live tissue sample were compensated by chemometrics techniques such as principle component analysis (PCA) and partial least squares (PLS) regression. The effect from mouse body temperature changes on NIR spectral data was also considered. This study showed that the compensation of variations from long-term measurement and temperature changes improved calibration accuracy of non-invasive blood glucose measurement.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2000년도 창립총회 및 학술발표회
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• pp.45-45
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• 2000

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.400.2-400.2
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• 2002

Near-infrared(NIR) reflectance spectroscopy was employed to qualify various ploymorphs. We collected 8 potential polymorphs forms of Medicine T for this study. Near-infared spectra of the powder samples contained in glass vials were obtained over the wavelength region of 1100-1750nm. There were the peak around 1560nm in the 6 spectra among 8 spectra. Principal component analysis(PCA) has been performed to examine the qualitative difference of 8 polymorphs PC space. (omitted)

• 한국작물학회지
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• 제39권5호
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• pp.489-494
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• 1994

맥주보리 품질에서 중요한 성분인 단백질함량을 NIRS를 이용하여 신원하고 정확하게 분석하기 위해 최적의 검양식 작성에 관한 일련의 시험을 실시한 결과는 다음과 같다. 1. Micro-Kjeldahl법에 의해 분석한 단백질함량을 이용하여 작성된 NIRS의 검양식중 2095 /1941/ 2282/ 2086nm 파장으로 구성된 검양식에서 결정계수($R^2$)가 0.95로서 가장 높았다. 2. NIRS의 2095/1941/2282/2086nm 파장으로 구성된 검양식으로 '92년도에 생산된 18품종을 분석한 결과 SDD가 0.47, SEP가 0.43, r이 0.95로서 매우 우수하였으며 평균 단백질함량도 Micro-Kjeldahl법의 10.25%와 동일하였다. 3. NIRS의 2095/1941/2282/2086nm 파장으로 구성된 검양식으로 '93년에 생산된 미지의 시료 31품종을 Micro-Kjeldahl법과 비교분석한 결과 SDD가 0.69, SEP가 0.67, r(simple correlation)이 0.91이었다. 4. 본 시험에서 작성된 NIRS의 검양식을 이용할 경우 Micro-Kjeldahl 분석치와 r값이 0.91로서 고도의 유의성이 인정되었으며 bias값을 보정해 주면 단백질함량의 평균값이 Micro-Kjeldahl법과 매우 근접된 값을 얻을 수 있어서 맥주보리 육종의 초기세대에서 단기간 다량의 계통을 분석할 수 있을 것으로 기대되었다.

• 생약학회지
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• 제44권4호
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• pp.344-349
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• 2013

Near infrared spectroscopy (NIRS) combined with multivariate analysis was used to discriminate the geographical origin of Alisma orientale from Korea (n=94) and China (n=72). Two-thirds of samples were selected randomly for the training set, and one-third of samples for the test set. Second derivative was used for the pretreatment of NIR spectra. Partial least square discriminant analysis (PLS-DA) models correctly discriminated 100% of the Korean and Chinese A. orientale samples. These results demonstrate the potential use of NIR spectroscopy combined with multivariate analysis as a rapid and accurate method to discriminate A. orientale according to their geographical origin.