Qualification of various polymorphs by near-infrared(NIR) spectrophotometer.

  • Lim, Hun-Rang (College of Pharmacy. Dongduk Women′s University) ;
  • Chang, Soo-Hyun (College of Pharmacy. Dongduk Women′s University) ;
  • Woo, Young-Ah (College of Pharmacy. Dongduk Women′s University) ;
  • Kim, Hyo-Jin (College of Pharmacy. Dongduk Women′s University)
  • Published : 2002.10.01

Abstract

Near-infrared(NIR) reflectance spectroscopy was employed to qualify various ploymorphs. We collected 8 potential polymorphs forms of Medicine T for this study. Near-infared spectra of the powder samples contained in glass vials were obtained over the wavelength region of 1100-1750nm. There were the peak around 1560nm in the 6 spectra among 8 spectra. Principal component analysis(PCA) has been performed to examine the qualitative difference of 8 polymorphs PC space. (omitted)

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