• Journal of Applied Biological Chemistry
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• v.61 no.1
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• pp.101-108
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• 2018

This study was conducted to establish optimized ${\beta}-glucan$ extraction method through enzymatic hydrolysis from Phellinus baumii and investigate ${\beta}-glucan$ contents and physicochemical properties. The optimal condition was obtained with the enzyme concentration of 0.66% (v/v), reaction time of 6.08 h ($R^2=0.9245$) and the ${\beta}-glucan$ contents from the Phellinus baumii extracts under the optimized condition was 1.9594 g/100 g. ${\beta}-Glucan$ yield (0.76-16.40%) of enzyme beta-glucan extract (EBE) was three fold higher than that of non-enzyme beta-glucan extract (NEBE). ${\beta}-Glucan$ purity (11.15-59.05%) of non-enzyme beta-glucan (NEB) and that of enzyme beta-glucan (EB) were higher than that of NEBE and that of EBE. ${\beta}-Glucan$ purity of EB (59.05%) and ${\beta}-glucan$ contents of EB (3.38 g/100 g) showed higher than those of others. Total sugar contents (0.61-1.17 mg/mL) showed that NEB and EB were higher than that of NEBE and EBE, EB had the highest total sugar content as 1.17 mg/mL, respectively. Protein contents (0.44-11.73 mg/mL) of NEBE and that of EBE were higher than that of NEB, that of EB. In FT-IR spectrum, the band at $890cm^{-1}$ of microcapsule was attributed to a ${\beta}-1,3-glucan$. The toxicities of ${\beta}-glucan$ from Phellinus baumii in both melanoma cell lines was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoli um bromide assay and ${\beta}-glucan$ from Phellinus baumii has no toxicity until $30{\mu}g/mL$. The effects of ${\beta}-glucan$ from Phellinus baumii on inhibition of cancer cell proliferation were detected by using a wound healing assay. The effect of NEB and EB were higher than NEBE and EBE, especially $30{\mu}g/mL$ of EB had the highest in both melanoma cell lines.

• Proceedings of the Korean Magnestics Society Conference
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• 2013.12a
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• pp.139-140
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• 2013

We investigate effect of a point defect on the pinning potential for a perpendicular magnetic domain wall based on the NEB method. We find that this method can give a reasonable value for the pinning potential and allows us to study the effect of various geometrical and magnetic properties on the pinning potential. In the presentation, we will discuss the effect of Ku and wire width on the pinning potential in detail.

• Proceedings of the Korean Magnestics Society Conference
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• 2014.05a
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• pp.120-121
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• 2014

We investigate the field-dependence of energy barrier for various cell diameters and two type of geometry through the NEB method. We find that the energy barrier can depend strongly on the cell size when the switching is governed by the domain wall motion. Moreover we also examine the cell size dependence of energy barrier for two type of cell geometry. In the presentation, we will discuss the effect of domain wall formation and more various cell size on the energy barrier in detail.

• Current Applied Physics
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• v.18 no.12
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• pp.1528-1533
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• 2018

The trajectories of adsorption and dissociation process of $O_2$ on the Al (111) surface were studied by the spinpolarized ab initio molecular dynamics method, and the adsorption activation energy was clarified by the NEB method with hybrid functionals. Three typical dissociation trajectories were found through simulation of $O_2$ molecule at different initial positions. When vertically approaches to the Al surface, the $O_2$ molecule tends to rotate, and the activation energy is 0.66eV. If $O_2$ molecule does not rotate, the activation energy will increase to 1.43 eV, and it makes the O atom enter the Al sublayer eventually. When the $O_2$ molecules parallel approach to the Al surface, there is no activation energy, due to the huge energy released during the adsorption process.

• Journal of Korean Society of Transportation
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• v.22 no.5
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• pp.139-149
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• 2004

As the expansion of road capacity has become impractical in many urban areas, congestion pricing has been widely considered as an effective method to reduce urban traffic congestion in recent years. The principal reason is that the congestion pricing may lead the user equilibrium (UE) flow pattern to system optimum (SO) pattern in road network. In the context of network equilibrium, the link tolls according to the marginal cost pricing principle can user an UE flow to a SO pattern. Thus, the pricing method offers an efficient tool for moving toward system optimal traffic conditions on the network. This paper proposes a continuous network design program (CNDP) in network equilibrium condition, in order to find optimal congestion toll for maximizing net economic benefit (NEB). The model could be formulated as a bi-level program with continuous variable(congestion toll) such that the upper level problem is for maximizing the NEB in elastic demand, while the lower level is for describing route choice of road users. The bi-level CNDP is intrinsically nonlinear, non-convex, and hence it might be difficult to solve. So, we suggest a heuristic solution algorithm, which adopt derivative information of link flow with respect to design parameter, or congestion toll. Two example networks are used for test of the model proposed in the paper.

• Journal of Internet Computing and Services
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• v.5 no.2
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• pp.85-95
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• 2004

The web-based project is seriously not efficient area at software engineering. In order to develop a web-based system, UI(User Interface) designers usually first design display layout and then business logic developers bring to complete the coding of the display layout source. In the case of maintenance, it goes through the same process, This kinds of web-based software development method were proposed by the various methods same as the tag library of JSP, But there are many problems to apply them and they are low productive comparing to the CIS based software development method, WFS(Neb Form System), which is suggested on this thesis, separates UI design from business logic on a web project and offers the better environment to develop web based software, Eventually WFS will improve the productivity to develop web based software.

• Journal of KIISE:Software and Applications
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• v.31 no.9
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• pp.1226-1232
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• 2004

Biometric authentication is rising technology for the security market of the next generation. But most of biometric systems are developed using only one of various biological features. Recently, there is a vigorous research for the standardization of various biometric systems. In this paper, we propose a web-based authentication system using three other verifiers based on functional, parametric, and structural approaches for one biometrics of handwritten signature, which is conformable to a specification of BioAPI introduced by BioAPI Consortium for a standardization of biometric technology. This system is developed with a client-server structure, and clients and servers consist of three layers according to the BioAPI structure. The proposed neb-based multiple authentication system of one biometrics can be used to highly increase confidence degree of authentication without additional several biological measurements, although rejection rate is a little increased. That is, the false accept rate(FAR) decreases on the scale of about 1:40,000, although false reject rate(FRR) increases about 2.7 times in the case of combining above three signature verifiers. So the proposed approach can be used as an effective identification method on the internet of an open network. Also, it can be easily extended to a security system using multimodal biometrics.