• Title/Summary/Keyword: N100

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N100 Amplitude Slopes in Major Depressive Disorder, Bipolar Disorder, Schizophrenia and Normal Controls (주요 우울 장애, 정신분열병, 양극성 장애 및 정상 대조군에서의 N100 진폭경사)

  • Yang, Eunkyoung;Lee, Seung-Hwan;Oh, Sunghee;Kim, Sangrae
    • Korean Journal of Biological Psychiatry
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    • v.16 no.3
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    • pp.181-189
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    • 2009
  • Objectives : N100 amplitude slope(the intensity dependence of the cortical auditory evoked potentials) is widely considered as an indirect indicator of central serotonergic neurotransmission. However, there are only a few studies about N100 amplitude slopes of major psychiatric disorders. In this study, we examined N100 amplitude slope differences among major depressive disorder(MDD), bipolar disorder(BD), schizophrenia (SCZ) and normal controls(NC). Methods : We measured the N100 amplitude slopes of 35 patients with MDD, 33 patients with BD, 27 patients with SCZ and 35 NC subjects. Amplitude differences from N1 to P2 at the five different sound intensities(55, 65, 75, 85 and 95dB) were examined at Cz electrode. The N100 amplitude slope was calculated as the linear regression of five N1/P2 peak-to-peak amplitudes across stimulus intensities. Results : BD patients showed significantly reduced N100 amplitude slope compared with NC(0.54${\pm}$0.70 vs. 0.96${\pm}$0.72, p=0.035). N100 amplitude slope of SCZ patients was significantly reduced compared with NC(0.50${\pm}$0.47 vs. 0.96${\pm}$0.72, p=0.027). N100 amplitude slope of BD patients was significantly lower than that of MDD patients(0.54${\pm}$0.70 vs. 0.94${\pm}$0.60, p=0.046). SCZ patients also showed significant reduction of N100 amplitude slope compared with MDD patients(0.50${\pm}$0.47 vs. 0.94${\pm}$0.60, p=0.036). There was no significant difference of N100 amplitude slope between MDD patients and NC(0.94${\pm}$0.60 vs. 0.96${\pm}$0.72, p=1.000). Conclusion : Interestingly, the N100 amplitude slopes of BD and SCZ were reduced compared to NC and MDD patients. Our results suggest the predictive use of N100 amplitude slope in making differential diagnoses of major psychiatric disorders. Clinical implications of N100 amplitude slope in major psychiatric disorders were discussed.

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Influence of N-P-K Nutrient Levels on Ozone Susceptibility of Tomato Plants (N-P-K 양분 수준이 토마토의 오존 감수성에 미치는 영향)

  • Ahn, Joo-Won;Ku, Ja-Hyeong
    • Korean Journal of Environmental Agriculture
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    • v.17 no.4
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    • pp.352-357
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    • 1998
  • This experiment was conducted to find out the effects of major nutrient levels(N, P, K) on ozone susceptibility of tomato plants(Lycopersicon esculentum Mill, cv. Pink Glory). Plants were grown in water culture system. A half-strength of Hoagland's nutrient solution was considered as a standard formulation($N_{100}$ $P_{100}$ $K_{100}$). The levels of major nutrients were adjusted through addition or removal of several fertilizer salts from the standard solution. Top growth was significantly decreased at the low nitrogen level or phosphorus removal condition. P- and K-contents of leaves were greatly decreased by removal of salts containing P and K from the nutrient solution. The rate of ozone injury was significantly increased when potassium was removed. However, the influence of nitrogen and phosphorus levels or high potassium level on injury occurrence did not show statistical significance compared to the standard solution. Ozone exposure resulted in reduction of chlorophyll, and increase of ethylene production, electrolyte leakage and malondialdehyde(MDA) contents. These changes were much more enhanced in plants grown at the potassium removal solution. Whereas the activity of superoxide dismutase(SOD) was low at the potassium removal treatment and this tendency remained after ozone exposure. These results indicated that potassium nutrient level in tomato plants is closely associated with the susceptibility to ozone injury.

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Investigation of the Hydrolysis Characteristics of Fish Oil by Means of Aspergillus oryzae Lipase Lipolase-100T (Aspergillus oryzae 유래의 리파제 Lipolase-100T에 의한 물고기 기름의 가수분해 특성 규명)

  • 우동진;조귀준;허병기
    • KSBB Journal
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    • v.14 no.3
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    • pp.259-263
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    • 1999
  • Fish oil was hydrolyzed with Aspergillus oryzae lipase, Lipolase-100T. The hydrolysis characteristics of Lipolsae-100T were investigated. Lipolase-100T showed 1,3-positional specificity which hydrolyzed acyl chains combined on the 1 or 3 position of triglyceride into free fatty acids. Lipolase-100T represented another property that the saturated fatty acids composing the triglyceride were hydrolyzed more easily that the polyunsaturated fatty acids(PUFAs). n-3 PUFAs, such as C16:4, C20:5 and C22:6, were hardly hydrolyzed, so that the concentrations of those in the mixture of glycerides were increased according to hydrolysis time. Especially docosahexaenoic acid(DHA), C22:6 showed the highest increase in the concentration. This result explained that n-3 PUFAs were combined on 2-position of triglyceride. When the hydrolysis of fish oil with Lipolase-100T 0.4 wt% was performed for 120 hr, n-3 PUFAs wt% was increased to 50 wt% in the mixture of glycerides. This result was obtained due to the 1,3-positional specificity of Lipolase-100T and positional specificity of n-3 PUFAs.

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Effects of $\textrm{NO}_3$-N:$\textrm{NH}_4$-N Ratio and Elevated $\textrm{CO}_2$ on Growth and Quality of Lactuca sativa L. in Nutrient Film Technique (NFT재배에서 $\textrm{CO}_2$ 시용과 배양액의 $\textrm{NO}_3$:$\textrm{NH}_4$비율이 결구상추의 생육 및 품질에 미치는 영향)

  • 원선이;조영렬;이용범
    • Journal of Bio-Environment Control
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    • v.5 no.2
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    • pp.120-130
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    • 1996
  • Crisphead lettuce(Lactuca sativa L.) was grown in NFT to investigate the effects of NO$_3$-N and NH$_4$-N ratio in nutrient solution and elevated $CO_2$ treatment in the crisphead lettuce growth. This experiment has been conducted under three different ratios of NO$_3$-N:NH$_4$-N(100:0, 75:25, 50:50) with two $CO_2$ concentration (control, 1500ppm ). The results are as follows; 1. In the case of not controlling pH and EC in nutrient solution, pH was gradually increased in NO$_3$-N:NH$_4$-N=100:0 treatment but rapidly decreased in the nutrient solution 2. Daily changes of NO$_3$-N and NH$_4$-N were observed without controlling the nutrient solution. In the treatments of NO$_3$-N:NH$_4$-N ratios were 75:25 and 50:50, NO$_3$-N absorption rates were 27.7% and 26.1%, while NH$_4$-N absorption rates were 87.9% and 71.2%, respectively. 3. There was little differences in total nitrogen of leaves. However phosphorus, potassium, calcium and magnesium contents were highly shown in the treatment of $CO_2$ 1500ppm and 100:0 ratio of NO$_3$-N:NH$_4$-N. 4. Higher $CO_2$ assimilation rate was shown in plants grown under $CO_2$ 1500ppm and 100:0 ratio of NO$_3$-N:NH$_4$-N. It dropped significantly with the increase of NH$_4$- N rates in nutrient solution. 5. Fresh weight, leaf number, root length and root weight of crisphead lettuce were far better in the treatment of $CO_2$ 1500ppm and 100:0 ratio of NO$_3$-N:NH$_4$-N. Growth differences by $CO_2$ elevation were not shown in other NO$_3$-N:NH$_4$-N treatments. 6. The highest nitrate contents of leaves were shown in NO$_3$-N single treatment but shown the lowest vitamin C contents. Nitrate contents of leaves were decreased by $CO_2$ but the effect was slight treatment.

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Efficiency Improvement of $N^+P$ Junction Solar Cell by Forming V-Groove on the Silicon Surface (V형 홈 형성에 의한 $N^+P$ 접합형 태양전지의 효율 개선)

  • Chae, Sang-Hun;Kim, Jae-Chang;Lee, Yang-Seong
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.21 no.1
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    • pp.45-50
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    • 1984
  • V-groove N+P solar cell is fabricated by thermal diffusion in silicon wafer with (100) crystal structure. To form the V-grooves in (100) silicon surface, a mixture of etylen-diamine, water, pyrocathecol is used as the etchant of anisotropic etching. Under light intensity of 100mW/$\textrm{cm}^2$, the efficiency of the V-groove solar cell is 2.5-3.5% greater than the conventional N+P solar cell and 0.4-0.6% greater than the texturized one.

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Effect of Pig Slurry Application on the Forage Yield of Sorghum X Sudangrass Hybrid and Leaching of NO3-N in Volcanic Ash Soil (제주 화산회토양에서 돈분액비 시용이 수수 X 수단그라스의 생산성 및 NO3-N의 용탈에 미치는 영향)

  • 박남건;고서봉;이종언;황경준;김문철;송상택
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.23 no.3
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    • pp.151-158
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    • 2003
  • This study was carried out to determine the effect of pig slurry applications on the forage yield of Sorghum${\times}$Sudangrass hybrid and leaching of $NO_3$-N in volcanic ash soil in Jeju. It was arranged as a randomized block design with seven treatments: chemical fertilizer ($N-P_2$$O_{5}$ $-K_2$O=200-l50-150kg/ha), pig slurry 200kg N/ha, pig slurry 300kg N/ha, pig slurry 400kg N/ha, pig slurry 100kg N/ha+chemical fertilizer 100kg N/ha, pig slurry 150kg N/ha+chemical fertilizer 100kg N/ha, pig slurry 200kg N/ha+chemical fertilizer 100kg N/ha. The mean dry matter yield of Sorghum${\times}$Sudan grass hybrid per ha for 4 years(1998 to 2001) was higher(p<0.05) in pig slurry 300kg N/ha(l7,279kg) and pig slurry 400kg N/ha(17,817kg) treatments than those of other treatments. The $NO_3$-N concentrations of leaching water at soil depth 30cm in all treatments were excess the standard of WHO with level of $10.0mg/\ell$ on 20 days of the seeding, but this $NO_3$-N concentrations found to be below $5.0mg/\ell$ on August.

Effects of Nonylphenol on the Secretion of Catecholamines and Adrenocortical Hormones from Short-Term Incubated Rat Adrenal Glands

  • Hee-Su Kim;Yong-Pil Cheon;Sung-Ho Lee
    • Development and Reproduction
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    • v.27 no.4
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    • pp.213-220
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    • 2023
  • Previously, we showed that a chronic-low-dose nonylphenol (NP) exposure resulted in histological changes with sexually dimorphic pattern in rat adrenal glands. We hypothesized that such structural changes are closely related to the hormonal secretory patterns. To test this hypothesis, we developed the short-term adrenal incubation method, and measured the levels of catecholamines and cortical steroids using the high-performance liquid chromatography with electrochemical detection (HPLC-ECD) and specific enzyme-linked immunosorbent assay, respectively. The norepinephrine (NE) levels in media from NP-treated female adrenal, except 100 pM NP, were significantly increased [control (CTL) vs 1 nM NP, p<0.001; vs 10 nM NP, p<0.05; vs 100 nM NP, p<0.001; vs 1 µM NP, p<0.01]. The NE secretion from male adrenal was higher when treated with 100 nM and 1 µM NP (CTL vs 100 nM NP, p<0.05; vs 1 µM NP, p<0.05, respectively). The aldosterone level in the female adrenal media treated with 100 pM NP was significantly decreased, on the other hand, that of media treated with 10 nM NP was significantly increased (CTL vs 100 pM NP, p<0.05; vs 10 nM NP, p<0.01). In male adrenal media, the aldosterone levels of 10 nM, 100 nM and 1 µM NP-treated media were significantly declined (CTL vs 10 nM NP, p<0.001; vs 100 nM NP, p<0.001; vs 1 µM NP, p<0.001). These results showed the NP treatment altered secretory pattern of aldosterone from adrenals of both sexes, showing sexual dimorphism. It may be helpful for understanding possible adrenal pathophysiology, and endocrine disrupting chemicals-related sexually dimorphic phenomena in adrenals.

Dry Matter Yield of Japanese Millet (Echinochloa crusgalli var. Frumentacea 〈Roxb.〉 Wight), Chemical Properties and Microbial Population of Soil as Affected by the Application of Fermented Sawdust Swine Manure in Cheju Volcanic Ash Soil Area (제주화산회토양에서 발효 톱밥 돈분 시용이 피의 건물수량, 토양의 이화학적 성질 및 토양 미생물에 미치는 영향)

  • Kim M. C.;Kim T. G.;Lee J. E.;Moon B. C.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.25 no.3
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    • pp.159-168
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    • 2005
  • This experiment was carried out during the period from May to October 1998 to determine the effect of fermented sawdust swine manure application (SSM) on the herbage production of Japanese millet and soil properties in the Cheju brown volcanic ash soil. The randomized block design (T1 : basic chemical fertilizer, N 200 kg/ha + $P_2O_5\;300 kg/ha+K_2O$ 200kg/ha ; T2 : 1/2 basic chemical fertilizer, N $100+P_2O_5\;150+K_2O$ 100kg/ha; T3 : 1/2 basic SSM, N 100kg/ha, T4:basic SSM, N 200kg/ha; T5:2 times basic SSM, N 400 kg/ha ; T6:4 times basic SSM, N 800 kg/ha) was used. At the same application level of nitrogen 200kg/ha, the application of $100\%$ chemical fertilizer (T1) had significantly lower dry matter yield than that of $50\%$ chemical fertilizer and $50\%$ SSM (T2) or $100\%$ SSM (T4)(p<0.01). Dry matter yield increased with an increase of SSM application to N 400kg/ha level but decreased at N 800 kg/ha level. P, K and Ca contents of Japanese millet tended towards to decrease with an increase of SSM level. The application of chemical fertilizer lowered P and K content of Japanese millet in comparison with that of SSM (p<0.05). pH, available phosphorus. exchangeable potassium, Ca and Mg content of soil studied showed a significant increase with an increase of SSM application level (p<0.05). However, at the same application level of N 200kg/ha, there was statistically no significant difference between chemical fertilizer and SSM in those contents of soil after experiment. The bacterial number of soil among microbial population increased with an increase of SSM level, in June, 1998 (p<0.05), but there was no regular tendency, in October. The rate of bacteria to fungus in soil had a tendency to decrease with an increase of SSM level. In conclusion, it is recommended to use N 400kg/ha of SSM or N 100 kg/ha of chemical fertilizer+N 100 kg/ha of SSM for Japanese millet.

Effects of Nitrogen Level on Nitrogen Partitioning and Harvest Index in Brassica napus L.

  • Lee, Hyo;Zaman, Rashed;Lee, Bok-Rye;Kim, Tae-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.38 no.2
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    • pp.140-144
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    • 2018
  • To investigate the impact of nitrogen (N) mineral on reproductive potential of Brassica napus L, plants were treated with different levels of N treatment ($N_0$; $N_{100}$; $N_{500}$). The half of N content for each treatment were applied at the beginning of the early vegetative stage and the rest was applied at the late vegetative stage. Nitrogen content in plant tissues such as root, stem and branch, leaf, pod and seed was analyzed and harvest index (HI) was calculated as percentage of seed yield to total plant weight. Biomass and nitrogen content were significantly affected by different levels of N supply. Biomass was significantly decreased by 59.2% in nitrogen deficiency ($N_0$) but significantly increased by 50.3% in N excess ($N_{500}$), compared to control ($N_{100}$). Nitrogen content in all organs was remarkably increased with nitrogen levels. N distribution to stem and branches, and dead leaves was higher in N-deficient ($N_0$) and N excessive plants ($N_{500}$) than in control ($N_{100}$). However, nitrogen allocated to seed was higher in control ($N_{100}$) than in other treatments ($N_0$ or $N_{500}$), accompanied by higher HI. These results indicate that the optimum level of N supply ($N_{100}$) improve HI and N distribution to seed and excessive N input is unnecessary.

Characteristics of InN thin films fabricated by reactive sputtering (반응성 스퍼터링에 의해 제작된 InN 박막의 특성)

  • 김영호;정성훈;문동찬;송복식;김선태
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1997.11a
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    • pp.173-176
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    • 1997
  • The III-V nitride semiconductor InN thin films which have the direct bandgap in visible light wavelength region have been deposited on Si(100) substrates and AIN/Si(100) substrates by rf reactive sputtering. InN thin films have been investigated on the structural, and electrical properties according to the sputtering parameters such as total pressure, rf power, and substrate temperature. It is found that optimal conditions required for fabricating InN thin films with high crystal Quality, low carrier concentration, high Hall mobility are total pressure 5mTorr, rf power 60W, substrate temperature 6$0^{\circ}C$ . InN thin films deposited on the AIN(60min.)/Si(100) substrates arid AIN(120min.)/Si(100) substrates showed remarkably high crystal quality and electrical properties. It is known that AIN buffer layer is to decrease free energy at interface between InN film and Si substrate, and then promoting lateral growth of InN films.

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