• Journal of the Korean Burn Society
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• v.23 no.2
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• pp.64-67
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• 2020

High-intensity focused ultrasound (HIFU) has been regarded as a non-invasive uterine-preserving treatment for women with uterine myoma. Numerous studies have reported that it is a relatively safe and effective treatment for uterine myoma. However, severe complications, such as deep thermal burn injuries, bowel perforation, and bladder injury, were reported on rare occasions. We report a case of a 4th degree burn on the lower abdomen after HIFU treatment for uterine myoma. Physicians must consider the possibility of deep thermal burn injuries when managing uterine myoma with HIFU.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.3
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• pp.157-167
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• 2012

Objectives: It is not yet clear wheather myomectomy for uterine myomas raises the pregnancy rate or not. And myomectomy has the risk of side effects and reducing pregnancy rate by causing tubal disorders, pelvic adhesions, endometriosis and so on. Therefore less invasive treatment to patients with uterine myoma who want to be pregnant is necessary. Methods: In this study, the patients who had uterin myoma were treated by oriental medical treatments such as herbal medication, acupuncture and moxibustion therapy. Results: After oriental medical treatments, their menstrual condition was improved and size of their myoma was decreased. And they were pregnant within two to five months. Conclusions: This case report shows that the oriental medical treatment is less invasive for uterine myoma and that is effective for patients with uterine myoma who want to be pregnant.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.4
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• pp.923-929
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• 2003

The purpose of this study is to examine various Oriental Medical approaches to uterine myoma treatments which have been previously proposed, and find out an appropriate method with the verification of its clinical acceptance. The treatment with GGT(Gami-gwichulikyeong-tang) and JGD (Jagungdan) has been applied to uterine myoma patients visiting Sangdang Oriental medical clinic. After the treatment, 81 cases showing significant results are selected and analyzed in terms of patients' age, social environment, previous history of treatment, condition of uterine myoma, chief complaint, and the comparison between menstrual phases before the treatment and those after it. As for the size change, no-change is dominant. For the change chief complaint take a favorable turn is better after the treatment. Color of menstruation, pathologic blood drainage, hypermenorrhea or menorrhagia. dysmentorrhea show high percentage of improvement. The results above show GGT and JGD are effective treatments for uterine myoma patients. These two are also similar to the typical prescription of Jingga, which is Gwichulpajing-tang. Thus GGT and JGD are effective to the treatment for Jingga and Jingga is one of the most valid Oriental Medical approaches to uterine myoma.

• The Journal of Korean Medicine
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• v.28 no.2 s.70
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• pp.114-125
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• 2007

Objectives : Uterine myoma is the most common pelvic benign tumor and may cause abnormal menstrual pattern. The growth of uterine myoma depends on hormones. The 7-zone-diagnostic system (CP-6000A) is a measuring system using skin resistance variability (SRV). The machine shows organic energy and was reported by the gynecologic department to detect functional abnormality of hypothalamus-hypophysis-ovarian axis (H-P-O). Our study was to investigate the SRV of women with uterine myoma by the 7-zone diagnostic system. Methods: Two groups were selected from those who took the CP-6000A test in the College of Korean Medicine Hospital of Sangji University from March 2003 to September 2006. They were divided into normal control (n=40) and uterine myoma groups (n=40). Electrodermal activity of the two groups was compared. Results : The mean value of electrodermal activity of the uterine myoma group was lower than that of thenormal group in all areas on first and second measurement. Especially, the mean value of the patient group was significantly lower than that of the normal group and fell below normal range in the 1, 2, and 3 areas on first and second measurement. Conclusions : The results suggest that women with uterine myoma may have organic energy deficiency and functional abnormality of the H-P-O axis. Further studies to determine the feasibility of this 7 -zone diagnostic system as a reliable diagnostic tool are needed.

• Journal of radiological science and technology
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• v.44 no.4
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• pp.307-313
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• 2021

The purpose of this study was to analyze the risk factors for uterine myoma diagnosed by ultrasonography in Korea women and to evaluate the risk. Among the patients who visited the outpatient department of obstetrics and gynecology at I hospital in Busin between January 2019 and March 2021 for the purpose of examination, 98 patients in the experimental group diagnosed with uterine myoma and 163 patients in the normal control group without other diseases were retrospectively conducted. Among the general characteristics of the subjects, age, body mass index, parity, and menopause showed significant differences between the myoma group and the normal control group. ROC(receiver operating characteristic) curve analysis and logistic regression analysis were performed to obtain the cut off value and odds ratio that can predict the occurrence of uterine myoma. The cut off value for the prediction of uterine myoma was determined to be 30 years old and a body mass index of 23 kg/m². After that adjusting for menopause, non menopausal cases with a body mass index of 23 kg/m² and over 39 years of age had the highest odds ratio of 6.04. Therefore, premenopausal women over 40 years of age require regular checkups and thorough weight management. This study was conducted with a small number of subjects. Therefore, there is a limit to generalizing to all Korean women. However, based on this study if a large scale prospective study considering various variables is made, it can play a role as a predictive marker in early detection of uterine myoma.

• 한국데이터정보과학회:학술대회논문집
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• 2006.04a
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• pp.235-240
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• 2006

Recently, in oriental medicine, the concerns of uterus myoma patients has been increased. We analyze the results of medical records for 1757 patients including 163 uterus myoma patients who visited D University Oriental Medical Center from March 2001 to December 2004. Thus, we invetigate the symptom scores which effect uterus myoma patients using logistic regression model.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.1
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• pp.272-285
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• 2006

Purpose : To report the clinical condition and the effect of oriental medicine treatment on patients with uterine myoma. Methods : Our research was based on 41 cases of uterine myoma through medical records from November, 2003 to March, 2005. Research items were age of patients at first visit, BMI, past medical history, pregnancy history, preceding operation, constitution, accompanied symptoms, results after Oriental medicine treatment, treatment period. And we analyzed statistically about factors to affect results after treatment. Results : Average age of patients was 34.8 years old. After Oriental medicine treatment, the size of myoma of 9 patients(47.4%) lessened or disappeared, the VAS pain score during periods was decreased in 17 patients(72.7%). Conclusion : The result showed that Oriental medicine treatment can be effective for the management of uterine myoma without hysterectomy.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.159-173
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• 2006

Purpose : The purpose of this study is to find out relation between DSOM scores and an attack of uterus myoma in oriental medicine. Methods : We analyze the medical records for 386 patients including 257 uterus myoma patients who visited Dongeui University Oriental Medical Center from May 2001 to June 2006. We investigate the DOSM symptom scores which effect uterus myoma patients using logistic regression model. Results : Logistic regression analysis indicate that 14 items of DSOM were associated with the myoma, and the results show that correct rate is equal to 79.79%, sensitivity is 83.66%, specificity is 72.09%. Conclusion : There is fair relation between DSOM scores(14 items of DSOM) and an attack of uterus myoma in oriental medicine.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.2
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• pp.38-48
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• 2008

Purpose: This study was conducted to investigate the effects of Hominis Placenta (紫河車) on the growth of human uterine myoma cells and cell apoptosis. Methods: Human uterine leiomyoma cells were cultured and treated with Hominis Placenta extract for 48 hours. Cell proliferation and activity was analyzed by MTT assay. We analyzed the cell cycle of human uterine myoma cells treated Hominis Placenta extract by FACS. Expression of proteins related to cell apoptosis (Bax, Bcl-2), cyclin-D1 and VEGF were evaluated by Western blotting method. Results: The human uterine myoma cells treated by Hominis Placenta extract didn't proliferate below the concentration of $10mg/m{\ell}$. And there was no remarkable difference on cell cycle analysis below the concentration of $10mg/m{\ell}$. The expression of Bax was decreased and the expression of Bcl-2 was increased after the treatment of Hominis Placenta extract. But the expressions of cyclin-D1 and VEGF were increased after the treatment of Hominis Placenta extract. Conclusion: This study suggests that Hominis Placenta induce uterine myoma cell apoptosis and have effect on the myoma cell proliferation in the concentraion below $10mg/m{\ell}$.

• YAKHAK HOEJI
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• v.51 no.6
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• pp.402-408
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• 2007

The aim of this study was to evaluate the effect of menstration among the influencing factors for the GnRH agonist (as G: depot goserelin 3.6 mg) therapy prior to the planned myomectomy for women who wanted to preserve their fertility. We reviewed total 48 patients. with the G therapy prior to the planned myomectomy from August 1st, 2005 to August 31st, 2006. The patients were classified by the G group (n=28) and the immediate surgery (as S) group (n=20). The G group (n=19) underwent the G therapy for 3 month courses, and then the efficacy was evaluated by menstruation and the myoma volumes. In the G group (n=19), therapy was effective, and the mean age was $32.4{\pm}6.5$ years. After the completion of G therapy, the mean volume of the myoma by ultrasonography was reduced to $85.2{\pm}71.2cm^3$ comparing of $430.6{\pm}248.8cm^3$ at first visit. The 11 patients had menstruation and the rest 8 patients with amenorrhea had less reduced volume of the myoma ($124.05{\pm}79.85cm^3\;v.s.\;329.41{\pm}234.0cm^3$ p<0.05). In the immediate S group, the myoma volumes by sonography was also checked for accuracy (${\alpha}=1.0$). As the result, the initial myoma volume had the positive correlations to the effectiveness with G therapy. However, the occurrence and frequency of the menstruation during the G therapy had a negative correlation. In conclusion, the use of G prior to the planned myomectomy was effective in reducing myoma volume and the menstruation.