• 농촌의학ㆍ지역보건
• /
• 제18권2호
• /
• pp.161-171
• /
• 1993

Mycoplasma pneumoniae(M. pneumoniae) is a primary pathogene of the respiratory tract in children. Most studies of such pneumonia involve a group of admitted patients in hospital, usually with major medical illness. We retrospectively studied the epidemiologic and clinical feature of 105 patients with serologically proven M. pneumoigic pneumonia treated at Gwang-Yang Hospital during a epidemic period of Jun. 1993 to Dec. 1993. All cases of pneumonia developed in this period were also reviewed and compared with serologically proven group. The results were as follows. 1. There were 63 males and 42 females, and the male /female ratio was 1.5 : 1. 2. More than half(57%) of cases belonged to 5-9 years of age group, and mean age was 6.5 years old. 3. Mean age was steadily decreased as prevalence of mycoplasmal pneumonia had been subsided. 4. The date of index case was June 26th, and that of median case was 3 months after the index case. 5. A major determinant of the outbreak seemed to be the population density rather than the population size. 6. Recurrence and serious complication were not observed in this period. 7. All cases of pneumonia developed in this period might be attributed to M. pnemoniae. These epidemiologic and clinical characteristics would contribute to the prevention and diagnosis of mycoplasmal pneumonia.

• 대한수의학회지
• /
• 제39권1호
• /
• pp.96-103
• /
• 1999

The present study was carried out to investigate the prevalence of mycoplasmal pneumonia of slaugter pigs in Youngnam area during the period from 1995 to 1997. The prevalence and pathomorphology of gross lung lesions were studied from 682 slaughter pigs in 8 swine herds. Gross lesions of pneumonia were recorded in the lungs of 442(64.8%), from 367 out of them(83.0%) were diagnosed as mycoplasmal pneumonia. Microbiological examination was performed with 197 lungs with gross lesions of mycoplasmal pneumonia of slaughter pigs from 8 different swine herds. M hyopneumoniae, P multocida, A pleuropneumoniae, Streptococcus spp, Corynebacterium spp, and H parasuis were detected in 24. 4%, 48.2%, 2.5%, 11.2%, 3.6%, and 1.0% of the pneumonic lungs, respectively. A total of 48 strains of M hyopneumoniae was investigated for their in vitro susceptibility to 8 antibiotics. Among the drugs tested, lincomycin, oxytetracycline, tiamulin and tylosin showed the high activity in minimal inhibitory concentration(MIC) of $0.04{\sim}5{\mu}g/ml$ while erythromycin showed low activity in MIC values($1.25{\sim}{\geq}40{\mu}g/ml$).

• Pediatric Infection and Vaccine
• /
• 제6권1호
• /
• pp.78-85
• /
• 1999

목 적 : 3세 이하에서 Mycoplasma pneumoniae 폐렴은 드문 것으로 알려져 있으나 최근 영유아에서도 Mycoplasma pneumoniae 폐렴이 많이 발생되고 있어서 3세 이하에서의 Mycoplasma pneumoniae 폐렴의 임상적 특성을 알아보고자 하였다. 방 법 : 1994년 1월부터 1997년 12월까지 4년간 경희대학교 부속병원 소아과에 입원한 환아 중 Mycoplasma pneumoniae 폐렴으로 진단된 3세 이하 환아 30명을 대상으로 의무기록 을 후향적으로 조사하여 임상양상, 혈청학적 소견, 방사선 소견, 합병증 및 치료 효과를 비교 분석 하였다. 결 과 : 1) 3세 이하에서 폐렴으로 입원한 환아 235명중 30명(12.7%)이 Mycoplasma pneumoniae 폐렴이었고 남녀비는 1.3 : 1로 남아에서 다소 높았다. 2) 발생시기는 여름 및 가을, 초겨울에 걸쳐 넓게 분포하였고 1994년과 1997년에 호발하였다. 3) 임상증상은 기침, 객담, 발열 순이었고, 그 외 콧물, 구토 증세도 나타났으며, 청진소견 상수포음이 26례(86.7%)로 가장 많았고, 그 외에 천명, 호흡음 감소가 나타났다. 4) 방사선 소견상 24례(80.0%)에서 폐침윤을 보였고, 일측성이 13례(43.3%), 양측성이 10 례(33.4%)였고, 흉막삼출이 있었던 경우는 1례(3.3%)였으며, 무기폐를 보인 경우는 없었고, 정상 소견이 6례(20.0%)였다. 6) 혈액검사당 백혈구 수는 정상인 경우가 24례(80.0%)였고, 호중구 증가를 보인 경우는 1례(3.3%)에 불과했으며, 호산구 증가는 10례(33.3%)에서 보였으며, 혈침속도 증가는 56.7%, CRP 양성률은 60.0%였다. 7) 냉응집소치가 양성인 경우는 19례(63.3%)였으며, Mycoplasma 항체치가 양성인 경우는 27례(90.0%)로 Mycoplasma 항체치가 더 높은 양성률을 보였으며 두 검사간 상관관계는 없었다. 또한 13례를 대상으로 시행한 Mycoplasma PCR 검사상 12례(92.3%)에서 양성반응을 보여 Mycoplasma pneumoniae 폐렴의 진단에 유용한 검사로 생각되나 이에 대한 임상적용 은 앞으로 더 연구되어야 할 것으로 사료된다. 8) 합병증으로는 피부발진 3례(10.0%)와 흉막삼출 1례(3.3%), 관절통 1례(3.3%)가 발생되었으나 경증이었고 후유증 없이 모두 완쾌되었다. 결 론 : Mycoplasma pneumoniae 폐렴은 3세 이하에서도 드물지 않게 발생되고 있으며, 임상양상의 특징으로는 방사선상 폐침윤이 없는 경우가 많고 합병증 발생이 적으며 증세가 경미하여 회복이 빠른 것 등이다. 3세 이하 폐렴 환아 중 진단되지 않고 누락된 환아가 다수 있을 것으로 생각되며 이 환아들을 포함하면 실제 발생률은 더 높을 것으로 사료된다.

• 한국동물위생학회지
• /
• 제30권3호
• /
• pp.305-312
• /
• 2007

The present studies was to seroepidemiological investigation with the related pneumonia due to a combination of both viral and bacterial agents. In selected herd in Jeonbuk-Iksan area of swine farms in 2006. The seroprevalence of antibody titers of PRRS, PCV-2 and mycoplasmal pneumonia were 87.2%, 69.8% and 47.4%, respectively. High seroprevalence of antibody in sow indicate that the infected sow major source of the diseases, and play an important role in circulation between production stage.

• 대한수의사회지
• /
• 제21권1호
• /
• pp.37-42
• /
• 1985

A disease characterized by an acute respiratory syndrome occured in a large fattening farm for calves located in Chung-nam Province, July, 1983. The first onset of the disease was in the herd consisting of 12 calves transported and mixed from the surburbs

• Journal of Korean Medical Science
• /
• 제33권43호
• /
• pp.281.1-281.2
• /
• 2018

• 한국임상수의학회지
• /
• 제22권4호
• /
• pp.365-370
• /
• 2005

Enzootic pneumonia caused by Mycoplasma hyopneumoniae is responsible for major economic losses in pig herds of world wide. Mycoplasma hyopneumoniae can also act as a primary pathogen of porcine respiratory disease complex followed by bacterial or viral infection. This study was carried out to investigate the prevalence of mycoplasmal pneumonia of slaughtered pigs in Jeju for two years. The lungs and sera of 214 cases were examined for gross and microscopic lesions of the lungs, immunohistichemistry test for Mycoplasma hyopneumoniae antigen and enzyme-linked immunohistichemistry assay (ELISA) for serum antibody titer. Pulmonary consolidation was observed in the lungs of 163 pigs $(76.1\%)$ with average gross lesion score of $6.0\%$., Bronchointerstitial pneumonia was most frequently observed $(78.5\%)$. The incidence of pulmonary consolidation was decreased in vaccinated pigs compared to that of non-vaccinated pigs. The rate of consolidation in the lungs was significantly decreased in the vaccinated pigs (P<0.05). Antigen of Mycoplasma hyopneumoniae was identified by immunohistichemistry test in the lungs of 174 pigs $(81.3\%)$. ELISh antibodies to Mycoplasma hyopneumoniae were detected in 154 pigs $(72.0\%)$. These results showed the prevalence of swine pneumonia and the incidence of Mycoplasma hyopneumoniae in slaughtered pigs of Jeiu province. We expect that these results would be helpful for the control of swine mycoplasmal pneumonia and porcine respiratory disease complex in Jeju.

• Tuberculosis and Respiratory Diseases
• /
• 제42권2호
• /
• pp.175-183
• /
• 1995

연구배경: Mycoplasma 폐렴은 주로 학동기와 청소년기에 호발되며, 성인에서는 발병빈도가 적고 증상이나 이학적 소견이 비특이적인 경우가 많다. 확진은 배양으로 가능하나 많은 시간이 필요하고 양성률에도 차이가 많아 조기 진단, 치료를 위해서는 혈청학적 검사소견과 임상적 양상의 분석이 mycoplasma 폐렴의 진단에 중요하다고 하겠다. 이에 저자들은 mycoplasma 감염으로 진단받은 성인 환자들의 임상상을 분석하였다. 방법: 폐렴으로 입원치료한 환자 중 M. pneumoniae 항체가가 1:40 이상이면서 한냉응집소가 1:64 이상인 경우를 확진례로, M. pneumoniae 항체가가 1:40 이상이거나 한냉응집소치가 1:64 이상이면서 임상소견이나 흉부X선소견이 M. pneumoniae 폐렴에 합당한 경우를 추정례로 하여 대상환자들의 연령 및 성별분포, 발병시기, 임상증상, 이학적소견, 혈청검사와 흉부X선 소견, 치료 및 경과 등에 대하여 관찰하였다. 결과: 1) 나이는 전 연령층에 고루 분산되어 있었으며 남녀비는 1:1 이었다. 2) 발병 월별로는 1월에 가장 많았으며(16.7%), 계절별로는 가을과 겨울에 가장 많았다(가을 30%, 겨울 33.3%). 3) 한냉응집소치는 12예(40%)에서 1:64 이상이었으며 발병2주경에 최고치에 도달하였고, M. pneumoniae 항체가는 5예(16.7%)에서 1:160 이었다. 4) 흉부X선 검사상 30예 중 28예에서 폐침윤이 관찰되었으며 침범부위로는 우폐 하엽이 33.3%로 가장 흔하였고, 양측 폐하엽을 침범한 경우는 23.3%에서 관찰되었다. 5) 입원치료 기간은 1주-2주가 33.3%로 가장 많았고, 86.7%가 4주이내에 치료에 반응을 보였다. 6) 내원시 발열이 있었던 경우는 17예(56.7%)였으며, erythromycin 치료를 받고 3일내에 70%에서 발열이 소실되었다. 결론: 성인 M. pneumoniae 폐렴은 소아에 비해 경한 양상으로 발현되는 경우가 많으며, 조기 발견, 치료함으로써 합병증없이 완치시킬 수 있는 병이다.

• 대한수의학회지
• /
• 제42권2호
• /
• pp.219-224
• /
• 2002

We report the seasonal prevalence of the mycoplasmal pneumoniae of swine (MPS) in slaughter pigs from July of 1999 to June of 2000. Gross finding of lung lesion observed and examined by dot-ELISA. In gross finding of lung lesion from 750 pig samples, 465 (62.0%) was MPS, and 129 (17.2%) was single or double infection with actinobacillosis and pasturellosis. However, 156 (20.8%) had no lesion. In seasonal detection, the prevalence was found to be winter (69.5%), autumn (63.5%), summer (60.0%) and spring (54.7%) in orderly frequency. In dot-ELISA, the result was showed the positive reaction (x16>titre) with 58.0% and negative (x4

• 한국동물위생학회지
• /
• 제29권1호
• /
• pp.27-36
• /
• 2006

This studies were carried out to investigate the rearing managements of pig farms and survey on pneumonia of the slaughtered pigs from 5 selected herds located in Jangsu, Jeonbuk. Isolated aerobic microorganisms from pneumonic lung were examined antibiotic susceptibility and tested serological antibody titers of the herd base. Prevalence rate of pneumonia were examined according to rearing and health management conditions of pig farms. Prevalence rate of pneumonia were detected in 78.8% and enzotic pneumonia. In 47.7%, pleuropneurnonia in 31.1%. In serological antibody titers showed the positive reaction with 54.4% in Actinobacillus pleuropneumonia serotype 5, 44.8% in Pasteurella multocida, 36.8% in A pleuropneurnonia serotype 2, 13.6% in Mycoplasmal pneumonia. Isolated aerobic microorganisms were examined antibiotic susceptibility and showed the high activity in gentamicin (58.3%), enrofloxacin (53.3%), norfloxacin (51.6%), cephalothin (41.7%) and low activity in amoxycillin (98.3%), oxytetracycline (98.3%), penicillin G (90.0 %), tetracycline (88.4%), ampicillin (88.3%). Farm managements were deficient effect of humidity in swine house but ammonia gas all appeared the 10 ppm that were recommendation density, below.