• 한국치위생학회지
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• 제13권4호
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• pp.651-657
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• 2013

Objectives : The purpose of the study is to verify the correlation between teenagers' use of internet and temporomandibular joint disorders(TMJD) because TMJD patients gradually increase in high school students. Methods : Subjects were 221 male high school students attending liberal arts and commercial schools from 9 to 21 of April, 2012. Students completed self-reported questionnaire. Results : TMJD symptoms included crackling joint (32.1%), headache (18.6%), malocclusion (8.1%), and jaw fatigue and muscular aching (7.2%). Students having at least one symptom accounted for 49.8%. Students having at least one poor habit accounted for 83.7% and 34.0% of the students used internet for 3 hours.. Score of students experiencing shoulders and chest pain was $5.13{\pm}1.10$ (p<0.05). Score of TMD afflicting area revealed $4.67{\pm}2.73$ (p<0.05) in mastication pain ($4.13{\pm}2.73$ (p<0.05)) due to long hours of internet use. Score of jaw fatigue related to muscular pain was $4.31{\pm}1.96$ (p<0.01). Duration of computer use was related to perceived TMJD symptoms (r=.153). Long duration of computer use was related to poor oral cavity habits (r=.157). Conclusions : Male high school students can perceive slight TMD which needs self management and regular check-ups and try to prevent TMD by utilizing measurement tools on TMD. Also, this study helps to prevent from worsening TMD by shortening hours of computer utilization.

• 대한인간공학회지
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• 제30권4호
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• pp.481-489
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• 2011

Objective: The aim of this study was to develop an ergonomic checklist (AULA: Agricultural Upper-Limb Assessment) which can assess the risks of the work-related upper limb disorders of farming tasks in Korea. Background: There are few assessment tools that reflect the current condition of agricultural works as of now. Method: AULA was developed as following three stages. First of all, a physiological experiment was conducted with selected 14 upper limb postures which are frequently occurred in farming tasks and then, an ergonomic checklist was developed with determining risk levels of each body posture based on the experimental findings. Lastly, the ergonomic checklist was validated by comparing with the existing assessment tools. Results: When comparing the AULA which was developed in this study with the existing assessment tools, it was found that the AULA may get over limits of the existing ones which are sensitive to particular postures, but aren't sensitive to the rest of them. Conclusion: It is predicted that the developed upper limb posture assessment tool which gets over the existing tools' limits and is proper for domestic farm work conditions, will help to reduce musculoskeletal disorders caused by farm works, by assessing farm works more easily and objectively. Application: By further developing the theoretical groundwork on the induction of muscular skeletal system symptoms relating to agricultural works, it is expected to improve the level of preventing and managing such muscular skeletal system symptoms in the field of agricultural and farming works, which is relatively less advanced in terms of labor difficulties.

• 산경연구논집
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• 제8권7호
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• pp.63-70
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• 2017

Purpose - Due to the lack of physical activities and the increase of sedentary behaviors such as screen time, the health condition for contemporaries has been deteriorating. This study is designed to investigate how the use of worktable or tools unfit for body and sedentary behaviors can exercise influence on muscular skeletal disease and how it has an impact on lowering work efficiency and the quality of life with the medium of the muscular skeletal disease. Research design, data, and methodology - The research has developed a questionnaire with 5 hypothesis. The questionnaires were also made by interview and E-mail. 350 copies of questionnaires were distributed and 315 questionnaire were used for the analysis as valid data responses. SPSS ver.22.0 were used and made Cronbach's and reliability test, correlation, Baron & α Kenny 3 step mediated regression analysis. Results - The research has found that living environment factors have positive effect on the occurrence of musculosketal disease. Particularly, repeated use of unfit worktable or tools has a positive effect on the muscular skeletal disorder. And sedentary lifestyle also has a positive effect on the disease. The musculoskeletal disease caused by living environment has a positive impact on lowering the work efficiency. This study has also showed that the muscular skeletal disease has mediated the relationship between the living environment factors and the decrease of work efficiency due to musculoskeletal disease. The musculoskeletal disorders can effect the decrease of the quality of life as well, for the decrease of work efficiency has a positive effect on lowering the quality of life. Conclusions - Sedentary lifestyles, the use of worktable unfit for body, and the repeated use of a tool have caused the increase of muscular-skeletal diseases, and reduction of productivity as well as the hight cost of medical treatment for our contemporaries. Understanding the cause of disease morbidity, finding ways to prevent the disease, and educating people about them would contribute not only to improvement of individual health but also to the advancement of welfare for all.

• Journal of Genetic Medicine
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• 제14권2호
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• pp.75-79
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• 2017

Duchenne and Becker muscular dystrophies (DMD and BMD, respectively) are X-linked neuromuscular disorders characterized by progressive muscle weakness and severe skeletal muscle degeneration. BMD is a milder form with a later onset. Patients with BMD tend to survive much longer than those with DMD. The differentiation between DMD and BMD is important in the genetic counseling of affected patients and their families. Since muscle biopsies are invasive procedures, the differential diagnosis of BMD and DMD is often dependent on the mutation identified in the DMD gene in affected patients. However, when a novel DMD mutation is identified, the differential diagnosis should be based on muscle biopsy findings with other clinical findings. Here we describe two Korean patients with BMD confirmed by muscle biopsy and genetic testing. Two novel exonic deletions in the DMD gene were identified.

• 대한인간공학회지
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• 제20권2호
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• pp.71-82
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• 2001

Twisting posture in lifting tasks has been identified as a risk factor of low back pain. However, it has been usually estimated in terms of compressive stress or muscular activity. Thus, this study was conducted to predict the influence on muscular fatigue during lifting simulation. Fifteen young and healthy subjects were recruited and performed isometric trunk exertions during upright standing, two-level flexions and five-level asymmetric twisting conditions. EMG signals from five primary trunk muscles in right part of body were collected during 20sec for 45 different lifting conditions. RMS(root mean square) and MPF(mean power frequency) parameters were used to analyze the EMG signals. Twisting postures were significant in right erector spinae(ERSR), right latissimus dorsi(LATR), right internal oblique(INOR) for muscular activities. Especially, when trunk was $30^{\circ}$ CCW twisting posture. ERSR and INOR activities increased respectively by 11% and 3%. Regarding the trunk muscle fatigue, we found that MPF shifts in twisting posture increased 2.3 and 2.6 times for ERSR and INOR muscles respectively. Therefore, It is probable for workers to suffer from low back disorders when they were exposed to a extreme twisting posture during prolonged lifting. This study suggests NIOSH(National Institute for Occupational Safety and Health) lifting equation needs the time-duration multiplier in addition to asymmetric multiplier.

• 대한임상독성학회지
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• 제3권1호
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• pp.63-66
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• 2005

Toluene is an aromatic hydrocarbon found in glues, cements, and solvents. It is known to be toxic to the nervous system, hematopoietic system, and causes acid-base and electrolyte disorders. Acute respiratory failure with hypokalemia and rhabdomyolysis with acute renal failure should be considered as potential events in protracted glue sniffing. We reported the case of 26-year-old woman was admitted to the emergency department with the development of respiratory failure and altered mentality due to hypokalemia after chronic glue sniffing. She was weaned from the ventilator 3 days later after potassium and sodium bicarbonate replacement and was discharged without respiratory symptoms and other complications.

• The Journal of Korean Physical Therapy
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• 제10권1호
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• pp.155-171
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• 1998

Interest in mannual therapy appears to continue to grow among physical therapists. The term 'mannual therapy' has traditionally been associated with physical therapists who examine and treat Patients who have disorders related to the neuro-muscular-articular system.. The manipulative means skilled and specialised use of manual and/or mechanically applied movement techniques, as a part of comprehensive orthopaedic physical therapy for disorders of the moving parts of body. Physical therapists use a large variety of manually applied examination procedures as part of the clincal decision-making process. The purpose of this article is to define and clarify the basic concepts of mannual therapy by comparing the geneal concepts and evaluation schemes of James Cyriax, John McM. Mennell, Geoffrey Maitland, Freddy Kaltenborn, Robin McKenzie, and Ola Grimsby. This article stresses the importance of developing stills in evaluation. Gimsby's approch is presented as a example of modem mannual therapy.

• BMB Reports
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• 제51권7호
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• pp.327-337
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• 2018

Lamin A and its alternative splicing product Lamin C are the key intermediate filaments (IFs) of the inner nuclear membrane intermediate filament. Lamin A/C forms the inner nuclear mesh with Lamin B and works as a frame with a nuclear shape. In addition to supporting the function of nucleus, nuclear lamins perform important roles such as holding the nuclear pore complex and chromatin. However, mutations on the Lamin A or Lamin B related proteins induce various types of human genetic disorders and diseases including premature aging syndromes, muscular dystrophy, lipodystrophy and neuropathy. In this review, we briefly overview the relevance of genetic mutations of Lamin A, human disorders and laminopathies. We also discuss a mouse model for genetic diseases. Finally, we describe the current treatment for laminopathies.

• Annals of Clinical Neurophysiology
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• 제22권2호
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• pp.51-60
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• 2020

Muscle pathology findings may guide the diagnosis of neuromuscular disorders since they are helpful for understanding the pathological processes causing muscle weakness and also provide significant clues for the diagnosis of muscle diseases. Recent advances in molecular genetics mean that a muscle biopsy can be omitted when diagnosing inherited muscle diseases. However, the muscle pathology can still play a role in those cases and its findings are also required when diagnosing inflammatory myopathies.

• 대한인간공학회지
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• 제25권2호
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• pp.1-10
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• 2006

In spite of the rapid increase of computer use in our everyday life, not much effort is undertaken to take measures to prevent Musculoskeletal Disorders(MSDs). In this paper, we suggest a movable armrest which would lower the exposure to the MSDs, especially on the vicinity of arm. The aim of this study is to determine whether there are differences in wrist angle variations, forearm muscular loads, comfort and normal performance between the invented movable armrest and a conventional armrest when using a computer mouse. Eight experienced VDU workers performed a standardized simple task set which consists of 15 detailed tasks with each armrest. The wrist angle variations in the right arm were registered by electrogoniometer and the muscle activities in the shoulder, deltoid and two extensors in the forearm were also registered by electromyograph. The subjects rated perceived comfort while performing the tasks with each armrest. Working with the invented armrest, compared to general, gave significantly decreased wrist angle variations at most of the detailed tasks of both biaxial movements. Moreover, as the distance of targets increased, the difference of muscle activities in two different situations trend to be increasing. At the same time, in work with invented armrest, the subjects rated more comfort and they showed decreased normal performances in 8 detailed tasks which were mainly caused by macro moving time.