• The Journal of Korean Physical Therapy
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• 제34권4호
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• pp.175-180
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• 2022

Purpose: Leg length discrepancy causes the posture deformation, gait asymmetry, and lower back pain. The purpose of this study is to investigate the correlation among functional leg length discrepancy (FLLD), muscle activity, muscle contraction onset time and vertical ground reaction force (vGRF) during simple lifting task. Methods: Thirty-nine subjects participated in this study. FLLD was measured from the umbilicus to medial malleolus of left and right leg using a tape. The subjects performed to lift a 10 kg box from the floor to chest. The muscle activity and muscle contraction onset time of rectus abdominis, erector spinae and rectus femoris was measured using EMG system and vGRF was measured by two force plate. Pearson correlation was used to fine out the correlation among FDDL, muscle activity, muscle contraction onset time and vGRF during simple lifting task. Results: Correlation between FLLD and difference of muscle activity of short-long side was very high (r>0.9) during simple lifting task. Correlation between FLLD and difference of muscle contraction onset time of short-long side was very high (r>0.9) during simple lifting task. And correlation between FLLD and difference of vGRF of short-long side was high (r>0.7) during simple lifting task. Conclusion: This study suggests that there is high correlation between FLLD and muscle activity, muscle contraction onset time, and ground reaction force during simple lifting task. Therefore, FLLD could negatively affect the postural balance.

• 대한약리학회지
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• 제8권2호
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• pp.55-61
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• 1972

Superprecipitation of actomyosin has been considered to be an in vitro model of the muscle contraction. The superprecipitation and ATPase activity (which supplies the energy for contraction) are influenced by several factors which are the large amount of changes in ionic strength, Mg and ATP concentrations. But those behaviors are found to be promptly influenced by the change in a small range of calcium concentration which can be controlled by the cellular function of muscle physiologically only in the presence of the modullatory proteins, tropomyosin and troponin. In order to elucidate the precise roles of calcium in the muscle contraction and relaxation, the effects of calcium on the actin- myosin interaction was observed in the presence of tropomyosin and troponin using the superprecipitation system. The results are summarized as follows: 1. EGTA (glycol ether diaminetetraacetic acid)prolonged the initiation of the superprecipitation of natural actomyosin. 2. Superprecipitation curve was declined by adding EGTA at the time when tile curve reached the half- maximum. The degree of declining was proportional to the amount of EGTA added. Especially, upon adding 0.25 mM EGTA the curve was lowered to the level before the protein superprecipitated. But addition of EGTA did not affect the curve after attaining the maximum. 3. Superprecipitation of Perry myosin B was not affected by EGTA added both before and during the course of the reaction. 4. Tropomyosin did not change the response of Perry myosin B to EGTA added at any time of the reaction. 5. Troponin also did not change the response of Perry myosin B to EGTA. 6. Both tropomyosin and troponin together rendered the Perry myosin B to obtain the same response as natural actomyosin to EGTA. 7. It was concluded that actin-myosin interaction was influenced by the minute change of calcium concentration only in the presence of both tropomyosin and troponin. We could reproduce the contraction and relaxation of the muscle in vitro under the presence of ATP by changing the calcium concentration.

• 대한의용생체공학회:의공학회지
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• 제31권3호
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• pp.245-250
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• 2010

The purpose of this study is to investigate the effects of sex and age and their interactions in premotor-time (PMT) of ankle muscle. Forty-eight elderly subjects (aged 65-90 years) and thirty young subjects (aged 19-27 years) participated in this study. Subject were instructed to perform maximal, voluntary, isometric, bilateral contraction of ankle muscle in reaction to auditory stimulus to determine PMT. As analysis variables, PMT, intrasubject variability of PMT and asymmetry of PMT between dominant and nondominant legs were used. As statistical analysis, two-way ANOVA was performed to assess the main effects of age group and sex and also their interactions. All variables showed significant age effects (p<0.01). However, no sex effect and interaction existed in all variables in both dominant and nondomiant legs. Theses results suggest that the PMT of ankle muscle is related to the age-related deterioration in postural control, however, not related to the sex-difference of fall incidence in the elderly population.

• 재활복지
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• 제14권3호
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• pp.225-256
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• 2010

본 연구는 초등학교 지적장애아동의 자세조절 특성을 파악하기 위해 시각, 안뜰감각 그리고 몸감각을 조합하여, 실험 조건에 따라 자세유지를 위하여 어떤 감각을 활용하고 있는지, 부적절한 감각자극에 대해서 통합시스템에서 어떻게 반응하는지, 외부 동요에 대해 신경근육의 자세조절 전략 시 동원되는 근육의 수축 개시시간과 개시순서를 각각 측정하여, 지적장애 아동의 자세조절 특성을 살펴보고, 나아가 초등학교 지적장애아동과 일반아동 간에 어떠한 차이가 있는지를 비교분석하여 자세조절능력 향상 프로그램에 적용 시 방향을 제시해주는데 있다. 이를 위하여 성별과 연령을 고려하여 초등학교 지적장애아동 26명과 일반아동 26명의 아동으로부터 자세조절능력을 비교하였다. 그 결과 자세조절과 감각계와의 관계를 파악한 평형점수와 감각활용 분석, 엉덩관절 전략에 의지하는 자세조절 전략, 근수축 개시지연과 근수축 개시순서의 변화 등을 종합해 볼 때 초등학교 지적장애아동의 자세조절의 문제는 운동시스템, 감각시스템, 통합시스템의 자세조절 시스템 전반에 걸친 총체적인 문제로 나타났다. 따라서 초등학교 지적장애아동의 자세조절 문제 해결을 위해서는 운동시스템, 감각시스템, 통합시스템을 포함하는 포괄적 자세조절 훈련 프로그램의 접근이 필요하다는 것을 알 수 있다. 자세조절 프로그램을 구성할 때, 다양한 감각을 제공하여 주고, 제공된 감각을 효율적으로 활용할 수 있는 감각훈련과 함께 고위중추에서 입력된 감각들을 정상적인 자세조절 발달에 활용할 수 있도록 훈련 시켜주어야 한다. 적응 반응을 계획하고 조직화하여 의미 있는 활동을 통해 중추신경계의 처리능력을 향상시키는 치료프로그램이 제공되어야 한다. 또한 자세조절을 안정적으로 할 수 있는 안정성 한계를 넓힐 수 있는 신경발달학적 치료와 함께, 근골격계에서 빠른 근수축 반응과 효율적인 근수축 개시순서를 유발 할 수 있도록 고유수용성 운동조절 프로그램, 자세반응 촉진 프로그램과 같은 훈련이 필요하다고 할 수 있다.

• 재활복지공학회논문지
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• 제7권1호
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• pp.13-19
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• 2013

본 연구는 휠체어 사이클 경사로 주행 시 척수 손상으로 인한 하지마비 장애인의 상체의 근전도 특성을 평가하고자 하였다. 이를 위하여 척수손상 장애인 3명을 대상으로 $0^{\circ}$, $3^{\circ}$, $6^{\circ}$의 경사로에서 휠체어 사이클 주행을 하도록 하였으며, 이때 이두근, 삼두근, 전 삼각근, 상승모근, 광배근, 복직근의 근 활성 최대값과 수축 시간, 수축 개시 종료 시기를 측정 및 분석하였다. 본 연구 결과 휠체어 사이클의 경사로 주행 시 수축 시간과 근 수축 종료시간이 경사도가 증가함에 따라 유의하게 길어지고 지연됐으며, 광배근의 최대 근 활성도는 평지 주행보다 유의하게 증가하였다 (p<0.05). 이와 같은 결과는 휠체어 사이클의 경사로 주행 시 광배근의 과도한 사용을 의미한다.

• 한국운동역학회지
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• 제17권2호
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• pp.197-205
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• 2007

The purpose of this study is to analyze the muscle activations and Ground Reaction Force(GRF) in university judo players, and provide the guide of training in Judo. Using surface electrode electromyography(EMG), we evaluated muscle activity in 5 university judo players during the Judo Uke Movements. Surface electrodes were used to record the level of muscle activity in the Tibialis Anterior, Rectus Femoris, Elector Spinae, Gluteus Maximus, Gastrocnemius muscles during the Uke. These signals were compared with %RVC(Reference voluntary contraction) which was normalized by IEMG(Integrated EMG). The Uke was divided into four phases : Kuzushi-1, Kuzushi-2, Tsukuri, Kake. The results can be summarized as follows: 1. The effective Uke Movements needs to short time in the Kake Phase 2. The Analysis of Electromyography of Uke Movements in Supporting Leg; TA(Tibialis anterior) had Higher %RVC in the Kuzushi Phase, RF(Rectus Femoris) had Higher %RVC in the Tsukuri Phase, GM(Gluteus Maximus) had Higher %RVC in the Kake Phase 3. The ground reaction force for Z(vertical) direction was showed increase tendency in Kuzushi phase, Tsukuri phase and decrease tendency in Kake phase.

• 대한의용생체공학회:의공학회지
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• 제33권2호
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• pp.98-103
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• 2012

The purpose of this study was to compare premotor time(PMT) and electro-mechanical delay(EMD) between sitting and standing posture. Twenty four healthy young subjects(12 women and 12 men) participated in this study. Subjects were instructed to perform maximal, voluntary, isometric contraction of ankle muscle(tibialis anterior and gastrocnemius muscles) in reaction to auditory stimulus. PMT and EMD, calculated from stimulus, EMG and torque profile were compared between sitting and standing postures. As statistical analysis, paired t-test was performed to assess difference between sitting and standing posture. In both tibialis anterior and gastrocnemius muscles, EMD was found to be significantly longer for standing than sitting. However, PMT in standing posture was longer than that in sitting posture only in gastrocnemius muscles. These result indicate that increased reaction time, particularly, increased EMD of ankle muscles in standing posture may be caused by co-contraction of ankle muscles for postural control in standing posture.

• IMMUNE NETWORK
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• 제9권3호
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• pp.106-113
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• 2009

Background: We previously demonstrated remarkable differences in the expression of IL-8/CXCL8 in aortic tissues and vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) compared to VSMC from normotensive Wistar-Kyoto rats (WKY). In the present study, we investigated the direct effect of IL-8/CXCL8 on expression of 12-lipoxygenase (LO), a hypertensive modulator, in SHR VSMC. Methods: Cultured aortic VSMC from SHR and WKY were used. Expression of 12-LO mRNA was determined by real-time polymerase chain reaction. Phosphorlyation of ERK1/2 and production of 12-LO and angiotensin II subtype 1 ($AT_1$) receptor were assessed by Western blots. IL-8/CXCL8-stimulated DNA synthesis was determined by measuring incorporation of [$^3H$]-thymidine. And effect of IL-8/CXCL8 on vascular tone was determined by phenylephrine-induced contraction of thoracic aortic rings. Results: Treatment with IL-8/CXCL8 greatly increased 12-LO mRNA expression and protein production compared to treatment with angiotensin II. IL-8/CXCL8 also increased the expression of the $AT_1$ receptor. The increase in 12-LO induced by IL-8/CXCL8 was inhibited by treatment with an $AT_1$ receptor antagonist. The induction of 12-LO mRNA production and the proliferation of SHR VSMC by IL-8/CXCL8 was mediated by the ERK pathway. The proliferation of SHR VSMC and the vascular contraction in the thoracic aortic ring, both of which were induced by IL-8/CXCL8, were inhibited by baicalein, a 12-LO inhibitor. Conclusion: These results suggest that the potential role of IL-8/CXCL8 in hypertensive processes is likely mediated through the 12-LO pathway.