• Fisheries and Aquatic Sciences
• /
• 제17권1호
• /
• pp.95-103
• /
• 2014

This study was carried out to investigate the influences of dietary levels, ratios and sources of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the growth and fatty acid compositions of juvenile olive flounder Paralichthys olivaceus. Sixteen diets containing five levels of EPA (0.5%, 1.0%, 1.5%, 2.0%, and 4.0%), five levels of DHA (0.5%, 1.0%, 1.5%, 2.0% and 4.0%), three ratios of EPA/DHA (75/25, 50/50 and 25/75), two levels of squid liver oil (5% and 10%) and a control diet containing 5% soybean oil were hand-fed to triplicate groups of fish (average weight, $9.7{\pm}0.3g$) for 8 weeks. Survival, specific growth rate, feed efficiency and protein efficiency ratio of fish were not affected by dietary EPA and DHA levels or ratios. Also, the dietary treatment had no significant effect on the lipid and protein contents of muscle and whole body of fish. A corresponding increase in the EPA and DHA contents of fish occurred with increasing EPA and DHA levels in their diets. Our results suggest that juvenile olive flounder require a dietary EPA level of approximately 0.32% in the presence of 0.74% DHA for suitable survival and growth, and that EPA and DHA levels in fish muscle can increase to as much as 32% and 53%, respectively, of the total fatty acid content.

• 한국어병학회지
• /
• 제14권1호
• /
• pp.46-53
• /
• 2001

본 연구에서는 경골어류인 나일틸라피아(Oreochromis niloticus)와 이스라엘잉어(Cyprinus carpio)의 장관에 대한 neurokinin-1(NK-1)수용체 효능제인 substance p(SP)와 neurokinin-2(NK-2)수용체 효능제인 neurokinin A(NKA)의 수축활성과 작용기전을 비교 분석하였다. SP와 NKA는 모두 나일틸라피아와 이스라엘잉어의 장관 평활근에 대하여 농도 의존적인 수축반응을 나타내었다. 그러나 이들에 의한 수축반응의 경향은 어종에 따라 다르게 나타났다. 즉, 나일틸라피아 장관 평활근에 대하여서는 SP가 NKA에 비하여 높은 친화력과 효능을 나타내었으나, 이스라엘잉어의 장관 평활근에 대하여서는 SP와 NKA의 수축반응은 유의한 차이가 없었다. 나일틸라피아 및 이스라엘잉어의 장관 평활근에 대한 SP와 NKA의 수축반응들은 모두 NK-1 수용체 차단제인 L-732,138에 의해서는 비경쟁적으로 길항되었으나, NK-2 수용체 차단제인 MDL 29913에 의해서는 영향을 받지 않았다. 한편, 선택적 무스카린성 수용체 길항제인 atropine($5{\times}10^{-7}$M)및 신경절 차단제인 tetrodotoxin($2{\times}10^{-7}$M)은 나일틸라피아 및 이스라엘잉어의 장관 평활근에 있어서 SP에 의해 유발된 수축반응들은 모두 유의성 있게 억제시켰으나, NKA에 의해 유발된 수축반응들에 대하여서는 유의성 있는 영향을 나타내지 않았다. 이상의 결과들을 종합하여 보면, SP및 NKA는 모두 어류의 장관 평활근에 대하여 강력한 수축효과를 나타내나 그 작용기전은 다르다고 추정된다. 즉, SP및 NKA의 장관 수축작용은 주로 장관 평활근에 존재하는 NK-1 수용체를 매개한 직접적인 작용에 기인하는 것으로 사료되나 SP의 경우에는 tachykinin 수용체를 통한 직접작용 이외에도 콜린성 신경말단(cholinergic nerve terminal)을 자극하는 간접적인 경로도 관여하는 것으로 추정된다.

• 대한치과교정학회지
• /
• 제25권3호
• /
• pp.355-373
• /
• 1995

두개악안면 영역은 많은 해부학적 구조를 포함하는 근골격구조(musculodentos keletal system)로 두부골격의 구조, 악궁상태, 저작근의 형성 및 기능은 서로 밀접한 연관성을 가지고 있다. 두개악안면 영역의 성장과 발육은 유전적인 요인이외에 환경적인 요인들 즉, 두개안면부의 근육을 포함한 주위조직의 영향을 받는 것으로 이미 알려져 있다. 그러나 반대로 두개안면부의 골격구조가 변화되는 경우 이에 대응하여 두개안면근육의 기능 또한 변화, 적응되는지에 대해서는 체계적인 연구결과가 미흡한 상태이다. 저자는 골격형 제 III급 부정교합자의 악교정수술 전, 후의 근활성도의 변화에 대한 비교연구를 통해 두부 골격구조와 교합상태에 따른 저작근 기능의 상호관계 및 변화 양상에 대해 알아보고자 정상교합을 가진 성인남자 15명과 술전 및 술후 골격형 제 III급 부정교합자 각각 15명을 대상으로 측모두부 방사선사진과 저작효율검사 및 rest, clenching, chewing, swallowing시의 전측두근, 교근, 상순의 근활성도 검사를 시행하여 다음과 같은 결과를 얻었다. 1. 하악의 안정위(rest)에서 술전 부정교합군에서 술후군보다 전측두근, 교근, 상순에서 높은 활성도를 보였으며, 술후군에서는 상순에서만 정상대조군보다 의미있는 높은 근활성도를 보였다. 2. 최대교합(clenching)시는 술후군에서 술전 부정교합군보다 전측두근, 교근, 상순에서 높은 근활성도를 보였다. 3. 저작(chewing)시는 술후군이 술전 부정교합군보다 전측두근 및 교근에서 높은 활성을 보인 반면 상순에서는 감소된 근활성도를 보였다. 4. 연하(swallowing)시 술후군에서 상순은 술전 부정교합군보다 감소되었으나 정상대조군보다 증가된 근활성도를 나타냈으며, 각 군간에 전측두근 및 교근에서는 유의차가 없었다. 5. 저작효율은 술전부정교합군에서 정상대조군보다 낮았으며, 술후군에서 술전 부정교합군보다 증가되었으나 두군 모두 정상대조군과 유의차를 보였다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제18권4호
• /
• pp.532-537
• /
• 2005

Increasing of body weight has been one of the important economic factors in the poultry industry. Insulin-like growth factor (IGF)-I is a polypeptide that serves to regulate muscle development and body growth. Moreover, IGF-I is related to feed efficiency. However, there are few studies regarding the regulatory roles of chicken IGF-I/-II compared with that of mammals. Especially, the Korean Native Ogol Chicken (KNOC) has a lean body growth and its body weight is generally lighter than the broiler chicken. Therefore, this study was conducted to investigate associations among serum IGF-I/-II concentration, feed efficiency, and body growth in KNOC. The body weight and feed intake of KNOC were recorded from 20 to 36 weeks at 2 weeks intervals, and blood was taken every 2 weeks. Serum IGF-I/-II were measured by RIA. Chickens were divided into two groups, high and low serum IGF-I concentration. Generally, feed efficiency and growth performance (body weight and weight gain) in the high serum IGF-I group were higher than those of the low group during the experimental period. In particular, the body weight of the IGF-I high group were significantly different from those of the IGF-I low group at 34 and 36 weeks, respectively (p<0.05). Moreover, body weight, weight gain, and feed efficiency had a significant correlation with serum IGF-I at several weeks (p<0.05 and p<0.01). These results show that IGF-I plays an important role in body growth and suggests a possibility that serum IGF-I could be used as a selection marker for body growth in KNOC.

• 대한의생명과학회지
• /
• 제27권2호
• /
• pp.88-94
• /
• 2021

A whole-body compression garment (WBCG) is mainly used for cosmetic purpose in Korea. Another case for wearing the WBCG would be while exercising because it allows the body to move easily. But physiological effects of wearing WBCG to the body have not been known much. To investigate whether wearing WBCG would be helpful for conducting exercises, we measured physiological criteria, which could be influenced by the compression, such as cardiovascular and pulmonary function. Twelve female college students participated in this experiment. Increase of blood pressure was monitored in all of the participants when they wore a WBCG just for 10 minutes. Pulmonary function that requires skeletal muscle contraction was decreased by wearing a WBCG. Blood pressure measured after conducting exercise became even lower when wearing a WBCG than non-wearing. Interestingly, heart pulse remained lower when wearing a WBCG than non-wearing during the whole relaxing period after the exercise. Electrocardiogram (ECG) analyses showed that such lower heart rate largely depended on extension of QT time. For that reason, physiological efficiency index (PEI) was higher for wearing WBCG. These results indicate wearing WBCG could enhance exercise efficiency by lowering heart pulse.

• 한방재활의학과학회지
• /
• 제21권1호
• /
• pp.1-22
• /
• 2011

Objectives : This study was undertaken to verify the effects of Wolbigachul-tang1(WBCEx1) on obesity using high fat diet-induced male mice and to investigate the molecular mechanisms involved. Methods : 8-week old C57BL/6 mice were divided into 5 groups; lean control, obese control, WBCEx1, 2, 3. After mice were treated with WBCEx1(water extract), 2(30% ethanol extract), 3(water extract; Ephedra sinica Stapf., Gypsum fibrosum) for 12 weeks, body weight gain, feeding efficiency ratio, plasma lipid and glucose metabolism, the messenger RNA(mRNA) expression of peroxisome proliferator activated receptor(PPAR)$\alpha$ target genes were measured. In addition, $PPAR{\alpha}$ target gene expression was examined in liver, white adipose tissue and skeletal muscle. Results : 1. WBCEx1-treated mice had significantly lower body weight gain and feeding efficiency ratio. 2. Consistent with the effects on body weight gain, WBCEx1 decreased the weights of epididymal and retroperitoneal white adipose tissue, inguinal subcutaneous adipose tissue, and brown adipose tissue. 3. WBCEx1 significantly decreased plasma triglyceride and total cholesterol levels. 4. The size of adipocytes were significantly decreased by WBCEx1, whereas the adipocyte number per unit area was increased. Hepatic lipid accumulation was decreased by WBCEx1. 5. WBCEx1 did not affect the mRNA expression of $PPAR{\alpha}$ target genes in liver, adipose tissue, and skeletal muscle. 6. Plasma asparate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN) and creatine concentrations were in the physiological range. Liver and kidney weights were significantly lower following WBCEx treatment compared with obese controls, indicating that WBCEx does not show any toxic effects on liver and kidney. Conclusions : These results suggest that WBCEx1-induced body weight reduction is associated with appetite control and mediated by a mechanism other than the activation of $PPAR{\alpha}$.

• Asian-Australasian Journal of Animal Sciences
• /
• 제29권10호
• /
• pp.1500-1507
• /
• 2016

Myostatin (MSTN) can negatively regulate the growth and development of skeletal muscle, and natural mutations can cause "double-muscling" trait in animals. In order to block the inhibiting effect of MSTN on muscle growth, we transferred zinc-finger nucleases (ZFN) which targeted sheep MSTN gene into cultured fibroblasts. Gene targeted colonies were isolated from transfected fibroblasts by serial dilution culture and screened by sequencing. Two colonies were identified with mono-allele mutation and one colony with bi-allelic deletion. Further, we introduced the MSTN-ZFN mRNA into sheep embryos by microinjection. Thirteen of thirty-seven parthenogenetic embryos were targeted by ZFN, with the efficiency of 35%. Our work established the technical foundation for generation of MSTN gene editing sheep by somatic cloning and microinjection ZFN into embryos.

• 근관절건강학회지
• /
• 제25권1호
• /
• pp.1-11
• /
• 2018

Purpose: The purpose of this study was to understand and describe the experiences of exercise maintenance in elderly with osteoarthritis (OA). Methods: Three focus group interviews were conducted with a total of 19 older adults with OA who have been exercising for more than six months. Results: Two main themes emerged from the analysis: the changing exercise in life's journey (exercise maintained by self and family affection, exercise maintained by social networking expansion, exercise changing for function and body-image and exercise changing for economic efficiency) and the exercise pervaded into the life (Exercise used as a side effect-free treatment, exercise internalized by will and a sense of accomplishment and exercise become daily routine habits). Conclusion: Despite the various problems associated with aging and OA, participants made exercise a part of their lives by changing it to fit their own functions, abilities and circumstances. It is necessary to emphasize the positive aspects of the overall situation and to provide appropriate education and exercise based on the theory as well as the individual's overall fitness and limitations.

• 로봇학회논문지
• /
• 제12권2호
• /
• pp.124-131
• /
• 2017

This paper present a novel approach to control the lower body power assistive exoskeleton system of a HEXAR-CR35 aimed at improving a muscular strength. More specifically the control of based on the human intention is crucial of importance to ensure intuitive and dexterous motion with the human. In this contribution, we proposed the detection algorithm of the human intention using the MCRS which are developed to measure the contraction of the muscle with variation of the circumference. The proposed algorithm provides a joint motion of exoskeleton corresponding the relate muscles. The main advantages of the algorithm are its simplicity, computational efficiency to control one joint of the HEXAR-CR35 which are consisted knee-active type exoskeleton (the other joints are consisted with the passive or quasi-passive joints that can be arranged by analyzing of the human joint functions). As a consequence, the motion of exoskeleton is generated according to the gait phase: swing and stance phase which are determined by the foot insole sensors. The experimental evaluation of the proposed algorithm is achieved in walking with the exoskeleton while carrying the external mass in the back side.

• Asian-Australasian Journal of Animal Sciences
• /
• 제18권5호
• /
• pp.692-698
• /
• 2005

Two experiments were conducted to examine the effect of graded levels of dietary chromium and leucine, and different fat sources on performance and body composition of broiler chickens. The results showed that chromium picolinate at 0.5 ppm significantly (p<0.05) lowered the carcass fat level. Gut weight and carcass water content were increased as a result of chromium treatment. Body weight, plucked weight, carcass weight, abdominal fat pad weight, breast yield and feed efficiency were unaffected by chromium treatment. Leucine did not interact with chromium to effect lean growth. Dietary leucine above the recommended maintenance level (1.2% of diet) markedly (p<0.001) reduced the breast muscle yield. The addition of fish oil to broiler diets reduced (p<0.05) the abdominal fat pad weights compared to birds on linseed diets. Fish oil is believed to improve lean growth through the effects of long chain polyunsaturated fatty acids in lowering the very low-density lipoprotein levels and triglyceride in the blood, in the meantime increasing glucose uptake into the muscle tissue in blood and by minimizing the negative impact of the immune system on protein breakdown. The amount of fat in the diet (2% or 4%) did not affect body composition.