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Corpus-based Korean Text-to-speech Conversion System (콜퍼스에 기반한 한국어 문장/음성변환 시스템)

  • Kim, Sang-hun; Park, Jun;Lee, Young-jik
    • The Journal of the Acoustical Society of Korea
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    • v.20 no.3
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    • pp.24-33
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    • 2001
  • this paper describes a baseline for an implementation of a corpus-based Korean TTS system. The conventional TTS systems using small-sized speech still generate machine-like synthetic speech. To overcome this problem we introduce the corpus-based TTS system which enables to generate natural synthetic speech without prosodic modifications. The corpus should be composed of a natural prosody of source speech and multiple instances of synthesis units. To make a phone level synthesis unit, we train a speech recognizer with the target speech, and then perform an automatic phoneme segmentation. We also detect the fine pitch period using Laryngo graph signals, which is used for prosodic feature extraction. For break strength allocation, 4 levels of break indices are decided as pause length and also attached to phones to reflect prosodic variations in phrase boundaries. To predict the break strength on texts, we utilize the statistical information of POS (Part-of-Speech) sequences. The best triphone sequences are selected by Viterbi search considering the minimization of accumulative Euclidean distance of concatenating distortion. To get high quality synthesis speech applicable to commercial purpose, we introduce a domain specific database. By adding domain specific database to general domain database, we can greatly improve the quality of synthetic speech on specific domain. From the subjective evaluation, the new Korean corpus-based TTS system shows better naturalness than the conventional demisyllable-based one.

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The Relationship among Life-satisfaction, Self-neglect, Psychological Well-Being of the Elderly (노인의 생활만족도, 자기방임, 심리적 행복감에 관한 연구)

  • Ahn, Seong Ah;Jung, Eun Young;Kong, Jeong Hyeon
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.3
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    • pp.253-260
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    • 2020
  • The purpose of this study is to verify the relationship between the elderly's life satisfaction, self-neglect, and psychological well-being and to provide the basis for the development of mediation program to improve the psychological well-being of the elderly. The subjects of this study were 143 elderly persons who living in J city of G province. For data analysis, SPSS WIn 21.0 program was used to calculate real numbers, percentages, the mean values, and standard deviation values, and to conduct t-test, ANOVA, Pearson correlation, and multiple regression analysis. The subjects' psychological well-being was analyzed according to their general characteristics. As a result, their subjective well-being had a positive correlation with their life satisfaction (r=.841, p<.001), and had a negative correlation with their self-neglect (r=-.501, p<.001). As a result of stepwise regression analysis, the factors affecting the psychological well-being of the elderly were life satisfaction (β=.787, p<.001), income source (β=-.114, p=.028), and the explanatory power of these variables was 71.3%. In order to improve the psychological well-being of the elderly through the results of this study, it is necessary to prepare various social systems suitable for the characteristics of the elderly.

Performance of DOT Relay System with MRC/GSC receiver in Rayleigh Fading Channels (레일레이 페이딩 채널에서 MRC/GSC 수신하는 DOT 릴레이 시스템의 성능)

  • Kim, Nam-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.5
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    • pp.11-16
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    • 2012
  • Opportunistic transmit cooperative relaying (OTR) system has been interested for its ability to mitigate the fading in wireless channel without multiple antennas in a small terminal. In OTR system, only the relays that the received Signal-to-noise ratio (SNR) from a source is greater than the threshold transmit to the destination. However, the receiving branches of a destination in a realistic system is fixed, the excess number of signals from the transmit relays does not improve the system performance and consequently increases power consumption. In this paper, we adopt Double Opportunistic Transmit (DOT) cooperative diversity system which controls the average number of transmit relays. Although the average number of the transmit relays can be controlled by adjusting the two thresholds in DOT system, the instantaneous number of transmit relays is varying in fading channel. Thus we propose Maximal Ratio Combining (MRC) or Generalized Selection Combining (GSC) according to the number of the signals from relays at the destination. The outage probability of the proposed system is derived in closed form. The analytical results show that the system performance is improved with the number of the branches. Also it is noticed that when the number of the branches is fixed, the outage probability decreases with the increase of the average SNR of S-R path and R-D path.

Production of vegetable oil in biomass (바이오매스에서 식물지방 생산)

  • Kim, Hyun Uk;Lee, Kyeong-Ryeol;Kim, Eun-Ha;Roh, Kyung Hee;Kang, Han Chul;Kim, Jong-Bum
    • Journal of Plant Biotechnology
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    • v.41 no.3
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    • pp.107-115
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    • 2014
  • Vegetable oils (triacylglycerols) produced mainly in seeds of plants are used for valuable foods that supply essential fatty acids for humans as well as industrial raw materials and biofuel production. As the demanding for vegetable oils has increased, plant metabolic engineering to produce triacylglycerols in biomass such as leaves has been considered and explored for alternative source of vegetable oils. Leaves are genetically programmed to supply the fixed carbon by photosynthesis to other organs for plant development and growth. Therefore, in order to produce and accumulate triacylglycerols in leaves, one should take account of multiple metabolic pathways such as carbon flux, competition of carbohydrate and fatty acid biosynthesis, and triacylglycerols turnover in leaves. The recent metabolic engineering strategy has showed potential in which the co-expression of three genes WRINKLED1, DGAT1, and OLEOSIN involved in the critical step for increasing the fatty acid synthesis, accumulating triacylglycerols, and protecting triacylglycerols, respectively produced higher amount of vegetable oils in leaves. Developing of genetically engineered plants producing vegetable oil in biomass at non-agricultural lands will be promising to the future success of the field.

Suceptibility to animal serum and antimicrobial agents of Campylobacter jejuni isolated from pigs and chicken (닭과 돼지에서 분리한 Campylobacter jejuni의 동물혈청 및 항균성 물질에 대한 감수성)

  • Lee, Soo-cheung;Kang, Ho-jo
    • Korean Journal of Veterinary Research
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    • v.29 no.4
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    • pp.493-501
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    • 1989
  • A total of 108 strains of C jejuni isolated from pigs and chickens were examined for the susceptibility to 10 antimicrobial agents and normal sera of cattle, sheep, guinea pigs and chickens. Minimal inhibitory concentration(MIC) ranges of antimicrobial agents to C jejuni isolates were $${\leq_-}1.56$$ to $${\geq_-}100{\mu}g/ml$$ for erythromycin, rifampin, streptomycin and tetracycline, 50 to $${\geq_-}100{\mu}g$$ for cephalothin, $${\leq_-}1.56$$ to $50{\mu}g$ for ampicillin, $${\leq_-}1.56$$ to $25{\mu}g$ for kanamycin and nalidixic acid, $${\leq_-}1.56$$ to $12.5{\mu}g$ for chloramphenicol and gentamicin. Resistance rates of C jejuni were showed to in order of rifampin(84.7%), tetracycline(56.2 %), erythromycin(17.1%) and ampicillin(3.8%), all of the strains were sensitive to chloramphenicol, gentamicin and kanamycin, and the incidence rates of resistant C jejuni were highly frequent in pig isolates than chicken isolates. The drug resistance patterns of 87 chicken isolates C jejuni to 9 antimicrobial drugs were showed 12 patterns, and Sm Ra Tc(24.1%), Sm Ra(21.8%) and Ra Tc(14.9%) were relatively common, and also 21 pig isolates were showed 6 patterns and Em Sm Ra Tc(57.1%) were most frequent. The majority of the isolates showed multiple drug resistance. Bactericidal activity of 10% normal sera from healthy animals were examined for 60min at $37^{\circ}C$. C jejuni were decreased from 0.4 to 1.0 ${\log}_{10}$(p<0.01), and serum susceptibility were high in order of guinea pig, sheep, chicken and cattle sera. Serum sensitivity of C jejuni Ch-39 strain in increased serum concentation up to 10, 20, 40 and 80% were highly significant. In the normal animal serum, the number of Ch-39 strain were decreased from $1.8{\times}10^4/ml$ to $2.7{\times}10^3/ml$ after 60 min incubation(p<0.01), but the numbers were decreased to $6.6{\times}10^3/ml$ in the heat inactivated normal serum for 30 min at $56^{\circ}C$. Bactericidal activity was restored in the heat inactivated normal serum after the serum of complement source was added.

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Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation

  • Lee, Hyeseon;Park, Young-Mi;We, Yu-Mee;Han, Duck Jong;Seo, Jung-Woo;Moon, Haena;Lee, Yu-Ho;Kim, Yang-Gyun;Moon, Ju-Young;Lee, Sang-Ho;Lee, Jong-Keuk
    • Genomics & Informatics
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    • v.15 no.1
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    • pp.2-10
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    • 2017
  • Early detection and proper management of kidney rejection are crucial for the long-term health of a transplant recipient. Recipients are normally monitored by serum creatinine measurement and sometimes with graft biopsies. Donor-derived cell-free deoxyribonucleic acid (cfDNA) in the recipient's plasma and/or urine may be a better indicator of acute rejection. We evaluated digital PCR (dPCR) as a system for monitoring graft status using single nucleotide polymorphism (SNP)-based detection of donor DNA in plasma or urine. We compared the detection abilities of the QX200, RainDrop, and QuantStudio 3D dPCR systems. The QX200 was the most accurate and sensitive. Plasma and/or urine samples were isolated from 34 kidney recipients at multiple time points after transplantation, and analyzed by dPCR using the QX200. We found that donor DNA was almost undetectable in plasma DNA samples, whereas a high percentage of donor DNA was measured in urine DNA samples, indicating that urine is a good source of cfDNA for patient monitoring. We found that at least 24% of the highly polymorphic SNPs used to identify individuals could also identify donor cfDNA in transplant patient samples. Our results further showed that autosomal, sex-specific, and mitochondrial SNPs were suitable markers for identifying donor cfDNA. Finally, we found that donor-derived cfDNA measurement by dPCR was not sufficient to predict a patient's clinical condition. Our results indicate that donor-derived cfDNA is not an accurate predictor of kidney status in kidney transplant patients.

Phylogenetic analysis of the medicinal mushroom and taxonomical positions of their commercial products (약용버섯의 계통분류 및 국내유통 Inonotus속내 종간 구별을 위한 신속동정법 개발)

  • Jin, Cheng-Yun;Jeong, Min-Jung;Kim, Gi-Young;Park, Jae-Min;Kim, Mun-Ok;Moon, Dong-Oh;Lee, Tae-Ho;Lee, Jae-Dong
    • Journal of Mushroom
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    • v.3 no.2
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    • pp.52-59
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    • 2005
  • The Aphyllophorales is a large order containing about 2,000 known species. Many of these are the bracket and coral fungi. The vast majority of these fungi are saprophytic on the plant debris. Many species are significant in decomposing plant remains, as they are able to digest cellulose or lignin that occurs in plant cell walls. Many of these fungi have been involved in everyday human affairs. A few were used medicinally by the Greeks and Romans as a remedy for many complaints, including colic, fractured limbs and bruises. Other bracket fungi have been used as curry combs for horses, as snuff, as razor strops and as a source of dye for clothing. The texture of the basidiocarp may be similar to that of cork, wood, leather, paper, or cartilage. Unlike the basidiocarps of the Order Agaricales, the basidiocarps of the Aphyllophorales are not fleshly and moist. Division of the members of the Aphyllophorales into genera was originally made on the basis of gross morphology of the basidiocarp and hymenium and Donk(1964) recognizes 22 families in this order. The species and genus whose typical in Aphylloporales were listed in Table. with related information. The ITS region sequence of some genus were found by BLAST search. Sequences retrieved from GenBank were visually aligned by the program CLUSTAL G. As a result, the medicinal mushroom was separated in four groups. In this multiple alignment, the sequence analysis among Fomes group, Inonotus group and Phellinus group showed high genetic similarity except Hericium group and Sparassis group.

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Association of Total Sugar Intakes and Metabolic Syndrome from Korean National Health and Nutrition Examination Survey 2001-2002 (한국 성인의 총당류 섭취와 대사증후군과의 관계 -2001년과 2002년도 국민건강영양조사자료를 이용하여-)

  • Chung, Chin-Eun
    • Journal of Nutrition and Health
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    • v.40 no.sup
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    • pp.29-38
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    • 2007
  • The purpose of this study was to establish an association between the percent of energy from total sugar and disease prevalence of obesity, hypertension, dyslipidemia, insulin resistance, and metabolic syndrome with the context of the current population dietary practice in Korea. The Korean National Health and Nutrition Survey, 2001 and 2002 dataset were used as the source of data for this research. Usual nutritional intakes for over 20 years old people were calculated from the two non-consecutive dietary intake data from KNHANES 2001 and 2002 dataset. SAS and SUDAAN were used for statistical analyses. Sample weighted means, standard errors, and population percentages were calculated, and multiple logistic regression model with adjustment for covariates were used to determine the odds ratios(ORs) and 95% confidence intervals. Subjects were categorized as 3 ways and compared the LS means and ORs for heath factors. First, subjects excluding pregnant women, were categorized according to percent of energy from the usual total sugar intakes as ${\leq}10%$, 11-15%, 16-20%, 21-25%, >25%. Risk of LDL cholesterol showed a tendency to increase in the '>25%' group compared to the '<10%' group. The risks of the other health effects did not show any significant differences. Second, the subjects were categorized considering both Acceptable Macronutrient Distribution Range(AMDR) from carbohydrate and %Energy from total sugar as 'CHO<55% & Total sugar ${\leq}10%$', 'CHO 55-70% & Total sugar 11-25%', and '$CHO{\geq}70%$ & Total sugar ${\geq}25%$'. The risk of obesity tended to increase in the '$CHO{\geq}70%$ & Total sugar ${\geq}25%$' group compared to the 'CHO<55% & Total sugar ${\leq}10%$'. Third, the subjects were categorized as 'CHO<55% & Total sugar ${\leq}10%$', 'CHO 55-70% & Total sugar 11-20%', and '$CHO{\geq}70%$ & Total sugar ${\geq}20%$'. The risk of obesity also tended to increase in the '$CHO{\geq}70%$ & Total sugar ${\geq}20%$' group compared to the 'CHO<55% & Total sugar ${\geq}20%$' group. In conclusion, risk of LDL cholesterol showed a tendency to increase in the over 25% total sugar intake group, and the risk of obesity tended to increase in the 20-25% total sugar intake and high carbohydrate intake group. The risks of hypertension, hyperlipidemia, insulin resistance, and metabolic syndrome were not associated with total sugar intakes. More research to elucidate the association for Korean between the intakes of total sugar, added sugar, glucose, fructose, and sweeteners and diseases prevalences shoud be excuted in the future.

The Effect of Emotional Sounds on Multiple Target Search (정서적인 소리가 다중 목표 자극 탐색에 미치는 영향)

  • Kim, Hannah;Han, Kwang Hee
    • Korean Journal of Cognitive Science
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    • v.26 no.3
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    • pp.301-322
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    • 2015
  • This study examined the effect of emotional sounds on satisfaction of search (SOS). SOS occurs when detection of a target results in a lesser chance of finding subsequent targets when searching for an unknown number of targets. Previous studies have examined factors that may influence the phenomenon, but the effect of emotional sounds is yet to be identified. Therefore, the current study investigated how emotional sound affects magnitude of the SOS effect. In addition, participants' eye movements were recorded to determine the source of SOS errors. The search display included abstract T and L-shaped items on a cloudy background and positive and negative sounds. Results demonstrated that negative sounds produced the largest SOS effect by definition, but this was due to superior accuracy in low-salient single target trials. Response time, which represents efficiency, was consistently faster when negative sounds were provided, in all target conditions. On-target fixation classification revealed scanning error, which occurs because targets are not fixated, as the most prominent type of error. These results imply that the two dimensions of emotion - valence and arousal - interactively affect cognitive performance.

Distribution and Exposure Prevalence of Carbohydrate-based Food Intake among Obese Korean Adults Based on the Health Examinees (HEXA) Study (한국 성인 비만 집단의 탄수화물 급원 식품 섭취 분포 및 노출 위험도: 대규모 한국인유전체 역학 자료 활용)

  • Han, Yuri;Kwon, Sung-Ok;Lee, Sang-Ah
    • Korean Journal of Community Nutrition
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    • v.22 no.2
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    • pp.159-170
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    • 2017
  • Objectives: The purpose of this study was to estimate the distribution and exposure prevalence of total carbohydrate intake and the carbohydrate-based foods such as rice, noodles, sweet potatoes, sweet drinks, milk and fruits and to characterize intake patterns among obese Korean adults. Methods: Subjects included 137,363 adults aged 40 years or older who participated in a Health Examinees (HEXA) Study. Multiple regression analysis of data from Semi-Quantitative Food Frequency Questionnaire (SQFFQ) identified food sources of carbohydrates. Weight, height and waist circumstance (WC) were measured, and the body mass index (BMI) was calculated. Obesity was defined as $BMI{\geq}25kg/m^2$ and abdominal obesity as $WC{\geq}90cm$ and ${\geq}85cm$ for males and females, respectively. Results: Obese adults appeared to have a higher total carbohydrate intake in the univariate analysis but had eaten less after adjustment for general and lifestyle factors, compared to normal weight adults (OR 0.78, 95% CI 0.73-0.82 for general obesity; OR 0.79, 95% CI 0.74-0.85, for abdominal obesity; P trend < 0.0001, respectively). Based on advance analysis for the food sources of carbohydrates, obese subjects had lower intake of rice (OR 0.86, 95% CI 0.68 -1.09 for general obesity; OR 0.87, 95% CI 0.67-1.13, for abdominal obesity; P trend < 0.0001, respectively) and higher intake of noodles (OR 1.21, 95% CI 1.16-1.27 for general obesity; OR 1.25, 95% CI 1.19-1.32, for abdominal obesity; P trend < 0.0001 respectively). With regard to other food sources of carbohydrates such as milk and fruits, intake was lower among obese compared to normal weight subjects. Conclusions: In the Korean middle-aged and older obesity groups, the intake of carbohydrates and the related foods was lower than in normal weight subjects, except for noodles. We conclude that a higher intake of noodles may enhance weight-gain. Therefore, this study suggested that the guidelines should consider the types of carbohydrate sources and the amount consumed from foods in order to provide proper guidance with regard to control and prevent obesity among Korean adults.