• Title/Summary/Keyword: Multiple response model

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A Study on the Acquisition of Usage Statistics based on SUSHI Project (SUSHI 기반 학술정보 이용통계 수집 모델 연구)

  • Kim, Sun-Tae;Lim, seok-Jong
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.35-39
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    • 2007
  • Recently Usage statistics are widely available from online content providers. However. the statistics are not yet available in a consistent data container and the administrative cost of individual provider-by-provider downloads is high. The Standardized Usage Statistics Harvesting Initiative (SUSHI) is developing an automated request and response protocol for moving Project COUNTER (Counting Online Usage of Networked Electronic Resources) Code of Practice usage statistics from providers to library electronic repositories. SUSHI will help libraries make better decisions by reducing the administrative overhead of using Project COUNTER statistics. Publishers in the recording and exchange of usage statistics for electronic resources, initially journals and databases. By following COUNTER's Code of Practice, vendors can provide library customers with Excel or CSV (comma delimited) files of usage data using COUNTER's standardized formats and data elements. The result is a consistent, credible, and compatible set of usage data from multiple content providers. On this study, We propose the acquisition model of usage data based on SUSHI for KESLI that is overseas electronic journal consortium in korea.

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A Design of Wide-Bandwidth LDO Regulator with High Robustness ESD Protection Circuit

  • Cho, Han-Hee;Koo, Yong-Seo
    • Journal of Power Electronics
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    • v.15 no.6
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    • pp.1673-1681
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    • 2015
  • A low dropout (LDO) regulator with a wide-bandwidth is proposed in this paper. The regulator features a Human Body Model (HBM) 8kV-class high robustness ElectroStatic Discharge (ESD) protection circuit, and two error amplifiers (one with low gain and wide bandwidth, and the other with high gain and narrow bandwidth). The dual error amplifiers are located within the feedback loop of the LDO regulator, and they selectively amplify the signal according to its ripples. The proposed LDO regulator is more efficient in its regulation process because of its selective amplification according to frequency and bandwidth. Furthermore, the proposed regulator has the same gain as a conventional LDO at 62 dB with a 130 kHz-wide bandwidth, which is approximately 3.5 times that of a conventional LDO. The proposed device presents a fast response with improved load and line regulation characteristics. In addition, to prevent an increase in the area of the circuit, a body-driven fabrication technique was used for the error amplifier and the pass transistor. The proposed LDO regulator has an input voltage range of 2.5 V to 4.5 V, and it provides a load current of 100 mA in an output voltage range of 1.2 V to 4.1 V. In addition, to prevent damage in the Integrated Circuit (IC) as a result of static electricity, the reliability of IC was improved by embedding a self-produced 8 kV-class (Chip level) ESD protection circuit of a P-substrate-Triggered Silicon Controlled Rectifier (PTSCR) type with high robustness characteristics.

Characteristics of Purinergic Receptor Expressed in 3T3-L1 Preadipocytes

  • Lee, Hyung-Joo;Baik, Joon-Heum;Kim, Min-Jeong;Kim, Na-Hyun;Kong, In-Deok
    • Biomedical Science Letters
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    • v.15 no.4
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    • pp.319-326
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    • 2009
  • Extracellular ATP elicits diverse physiological effects by binding to the G-protein-coupled P2Y receptors on the plasma membrane. In addition to the short-term effects of extracellular nucleotides on cell functions, there is evidence that such purinergic signalling can have long-term effects on cell proliferation, differentiation and death. The 3T3-L1 cell line derived from mouse embryo is a well-established and commonly utilized in vitro model for adipocytes differentiation and function. However, the distributions and roles of P2Y subtypes are still unknown in the preadipocyte. In this study, we identified the distributions and roles of P2Y subtypes in preadipocyte using $Ca^{2+}$ imaging and realtime PCR. ATP increased the $[Ca^{2+}]_i$ in a concentration-dependent manner. ATP increased $Ca^{2+}$ in absence and/or presence of extracellular $Ca^{2+}$. Suramin, non-selective P2Y blocker, largely blocked the ATP-induced $Ca^{2+}$ response. U73122, a PLC inhibitor, completely inhibited $Ca^{2+}$ mobilization in 3T3-L1 cells. The mRNA expression by realtime PCR of P2Y subtypes was $P2Y_2:P2Y_5:P2Y_6=1.0:12.5:0.3$. In conclusion, we showed that $P2Y_5$ receptor is a dominant purinergic receptor in preadipocytes, and multiple P2Y receptors could involve in differentiation and migration via regulating of intracellular calcium concentration.

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Seismic Response of a High-Rise RC Bearing-Wall Structure with Irregularities of Weak Story and Torsion at Bottom Stories (저층부에 약층과 비틀림 비정형성을 가진 고층 비정형 RC벽식 구조물의 지진응답)

  • 이한선;고동우
    • Journal of the Earthquake Engineering Society of Korea
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    • v.7 no.6
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    • pp.81-91
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    • 2003
  • Recently, many high-rise reinforced concrete(RC) bearing-wall structures of multiple uses have been constructed, which have the irregularities of weak(or soft) story and torsion at the lower stories simultaneously. The study stated herein was performed to investigate seismic performance of such a high-rise RC structure through a series of shaking table tests of a 1: 12 model. Based on the observations of the test results, the conclusions are drawn as follows: 1) Accidental torsion due to the uncertainty on the properties of structure can be reasonably predicted by using the dynamic analysis than by using lateral force procedure. 2) The mode coupled by translation and torsion induced the overturning moments not only in the direction of excitations but also in the perpendicular direction: The axial forces in columns due to this transverse overturning moment cannot be adequately predicted using the existing mode analysis technique, and 3) the hysteretic curve and the strength diagram between base shear and torque(BST) clearly reveal the predominant mode of vibrations and the failure mode.

Demographics, Social Media Use and Perceived Academic Stress of Secondary School Students in St. Thomas Aquinas College, Akure, Nigeria

  • Igbinovia, Magnus Osahon;Idhalama, Ogagaoghene Uzezi;Alex-Nmecha, Juliet C.
    • International Journal of Knowledge Content Development & Technology
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    • v.9 no.4
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    • pp.7-29
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    • 2019
  • The study was carried out to investigate the influence of demographics and social media use on perceived academic stress of secondary school students in St. Thomas Aquinas College, Akure, Nigeria. This was achieved using five research questions and four null hypotheses. The population of the study consisted of 1,107 students at ISCED level 3, out of which 286 were selected based on the Israel (2003) model for determining sample size. The Ex-Post Facto (EPT) research design of the correlational type was employed to investigate the study while questionnaire was used for data elicitation. Out of the 286 copies distributed, 192 (67% response rate) were retrieved and analyzed using descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (correlation and multiple regression). The findings revealed that there is high frequency of social media use among secondary school students, majorly for meeting new friends and chatting. The perceived academic stress (PAS) of the students was found to be moderate. Of the three demographics considered, only class had significant influence on PAS. Use of social media did not have significantly influence on PAS of the students. When combined, demographics and social media use predicted PAS; and when considered relatively, of the independent variables, only class as an aspect of demographics predicted PAS. Therefore, the authors concluded that PAS of secondary school students is not directly influenced by demographics (except for class) and social media use. Based on the study's conclusion, recommendations were made.

Expression of Epidermal Growth Factor-like Domain 7 is Increased by Transcatheter Arterial Embolization of Liver Tumors

  • Li, Zhi;Ni, Cai-Fang;Zhou, Jin;Shen, Xiao-Chun;Yin, Yu;Du, Peng;Yang, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1191-1196
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    • 2015
  • Background: Epidermal growth factor-like domain multiple 7 (EGFL7), recently identified as a secreted protein regulated by oxygen exposure, plays a critical role in promoting metastasis of hepatocellular carcinoma (HCC). Transcatheter arterial embolization (TAE) is widely used for treatment of HCC, resulting in hypoxia in tumors and surrounding liver tissues. Accordingly, we proposed the hypothesis that there could be a relationship between expression of EGFL7 and response to TAE. Materials and Methods: We established a rabbit VX2 liver tumor model using percutaneous puncture technique guided by computed tomography. TAE and sham embolization were performed and the results were confirmed by MRI 3 weeks after inoculation. We investigated the EGFL7 expression of the two groups at 6h and 3 days after intervention by means of immunohistochemistry and Western blotting. Results: Immunohistochemical staining demonstrated that the levels of EGFL7 protein significantly increased in the TAE-treated tumors compared with the control group at 6 hours (P=0.031) and 3 days (P=0.020) after intervention. Meanwhile, the relative EGFL7 protein detected in TAE group also up-regulated compared with the control group at 6 hours (P=0.020) and 3 days (P=0.024) after intervention. Conclusions: This study reveals an increase of EGFL7 expression in rabbit VX2 liver tumors after TAE. The role of EGFL7 in HCC, especially its biological behavior after TAE, needs further investigation.

Studies of Interface Continuity in Isogeometric Structural Analysis for Multi-patch Shell Components (다중 패치 쉘 아이소 지오메트릭 해석의 계면 연속성 검토)

  • Ha, Youn Doh;Noh, Jungmin
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.2
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    • pp.71-78
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    • 2018
  • This paper presents the assembling of multiple patches based on the single patch isogeometric formulation for the shear deformable shell element given in the previous study. The geometrically exact shell formulation has been accomplished with the shell theory based formulation and the generalized curvilinear coordinate system directly derived from the given NURBS geometry. For the knot elements matching across adjacent surfaces, the zero-th and first parametric continuity conditions are considered and the corresponding coupling constraints are implemented by a master-slave formulation between adjacent patches. The constraints are then enforced by a substitution method for condensation of the slave variables, thereby reducing the model size. Through numerical investigations, the important features of the first parametric continuity condition are confirmed. The performance of the multi-patch shell models is also examined comparing the rate of convergence of response coefficients for the zero and first order continuity conditions and continuity in coupling boundary between two patches is confirmed.

Factors Affecting Quality of life in the Elderly with Chronic Musculoskeletal Pain (근골격계 만성통증 노인의 삶의 질 영향요인)

  • Jeong, Hyesun;Lee, Yoonju
    • Journal of muscle and joint health
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    • v.25 no.2
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    • pp.92-103
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    • 2018
  • Purpose: This study aimed to identify factors affecting the quality of life of the elderly people with chronic musculoskeletal pain. Methods: The data were collected from 307 older adults aged 65 years or older with chronic musculoskeletal pain, who visited senior welfare centers in two cities. We used self-rated questionnaires including NRS for pain, WHOQOL-BREF for quality of life, Pain Response Inventory for coping responses to pain, and MSPSS for social support. Stepwise multiple regression analysis were performed using SPSS/WIN 23.0 to identify factors affecting the study subjects' quality of life. Results: The regression model explained 43% of quality of life, which was statistically significant (F=34.11, p<.001). Educational level of high school (${\beta}=.13$, p=.006), pain (${\beta}=-.13$, p=.013), restriction of function (${\beta}=-.13$, p=.028), accommodative pain coping (${\beta}=.24$, p<.001), family support (${\beta}=.18$, p<.001), colleague's support (${\beta}=.25$, p<.001), and perceived health status (${\beta}=.25$, p<.001) were identified as influential factors on subjects' quality of life. Conclusion: Developing integrative interventions is necessary to improve accommodative pain coping skills and to engage family and colleague in support for positive perception of older adults' health status and management of symptoms.

A study on user satisfaction in TUI environment (TUI 환경의 유저 사용 만족도 연구)

  • Choi, heungyeorl;Yang, seungyong
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.11 no.4
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    • pp.113-127
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    • 2015
  • An interface in smart device environment is changing to TUI(touch user interface) environment where a system is being controlled by physical touch, differently from a system controlled through conventional mouse and keyboard. What is more important than anything else in this TUI environment is to implement interface in consideration of learn ability and cognitive constructivism according to user's experience. Therefore, now is the time when it is necessary to carry out various studies on smart content design process going a step farther together with discussing the details of user's experience factor. Hence, this study was intended to look into what effect a user's experiential traits had on the production of contents for the purpose of measures for improving TUI user satisfaction in order to effectively realize contents in smart environment. Results were yielded by using a statistical empirical analysis such as cross-tabulation analysis according to important variable and user, paired t-test, multiple response analysis, and preference frequency analysis of user preference on the basis of a survey. As a result, a system was presented for implementing DFSS(Design For Six Sigma) process. TUI experience factor can be divided into direct habitual experience, direct learning experience, indirect habitual experience, and indirect learning experience. And in the results of study, it was possible to find that the important variables of this study had a positive effect on the improvement of use satisfaction with contents on the whole according to the user convenience of smart contents. This study is expected to have a positive effect on efficient smart device-based contents production by providing objective information according to empirical analysis to smart media-based developer and designer and presenting a model for improving the changed TUI usability.

A Comparative Status Analysis of Elementary and Middle School Students Preference for Science (초ㆍ중학생의 과학선호도 실태 비교 분석)

  • Yoon, Jin;Jeon, Woo-Soo
    • Journal of Korean Elementary Science Education
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    • v.22 no.1
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    • pp.65-80
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    • 2003
  • The purpose of this research was to survey and compare the status of science preference of elementary school students with that of middle school students. Preference for science was defined theoretically. According to theoretical model, a questionnaire was developed with piloting and consisted of three parts. First part was for background information, second part, for measurement of science preference and third for measurement of the relevant factors of science preference. The questionnaire was modified for primary school students. In July 2002, the questionnaire was administered to one class per grade of randomly selected 8 elementary and 8 middle schools all over the country and analyzed result of collected 696 elementary school students and 819 middle school students. Middle school students' science preference was low compared with elementary school students, especially in 'emotional response and 'valuational comprehension'. The preference for science became lower especially from 4th to 5th grade and from 8th to 9th grade. The differences of mean science preference were significant by gender. perception of science achievement. and future career choice. The average of science preference relevant factors of middle school students also became lower than elementary students, especially in 'educational factor'. Multiple regression analysis on the science preference showed that important factors were personal ability, the personal traits, rewards in school science and contents of school science, slightly different in elementary and secondary school. The way to promote students' preference for science was suggested on the analysis result.

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