• Title/Summary/Keyword: Multiple neoplasm

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Rapidly Grown Huge Mediastinal Benign Teratoma ; one case report (빠르게 성장한 거대 종격동 양성기형종)

  • 조성우;지현근;안현성;신윤철;남은숙
    • Journal of Chest Surgery
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    • v.33 no.6
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    • pp.521-524
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    • 2000
  • The benign teratoma is usually slow growing tumor, but we expirienced a case of primary huge mediastinal benign teratoma that had grown very rapidly, maximally during 3 years. The 14-year-old female patient was admitted to our hospital because of abnormal chest X-ray that showed 10$\times$10cm sized well definded mass with multiple calcificactions. but the mass was not present in chest X-ray perfomed on 3 years prior to admission. Under the diagnosis of teratoma, complete surgical resection was done by the left thoracotomy. The result of pathology was benign teratoma.

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Convergence Factors to Posttraumtic Growth in Female Urogenital Neoplasm Survivors (여성생식기 암 대상자의 외상 후 성장을 위한 융합적 관련 요인)

  • Kang, Hye-Kyung
    • Journal of the Korea Convergence Society
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    • v.8 no.10
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    • pp.115-124
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    • 2017
  • The purpose of the study was to investigate the convergence factors to posttraumatic growth(PTG) in survivors with female urogenital neoplasm survivors. A self-reported questionnaire was completed by 141 female urogenital neoplasm survivors via e-mail from September to October, 2016. The questionnaire consisted of PTG inventory, illness intrusiveness rating scale, cancer coping, family cohesion evaluation scale, and medical outcomes study social support survey. The data were analyzed by ANOVA, Pearson-correlation coefficient, and multiple regression analysis. Total score of PTG was 84.13points and statistically significant according to age, religion, marital status and positively associated with coping, family cohesion and social support. Results of the regression analysis showed religion(${\beta}=.127$), marital status(${\beta}=.081$), coping(${\beta}=.232$) and family cohesion(${\beta}=.415$), it were explained 44.7%. This study indicates that it is important to understand general characteristics of personal. And a convergent approach is needed to promote PTG by hospital and community.

Multiple Periosteal Chondroma of the Fourth Toe (제4족지의 다발성 골막 연골종)

  • Kim, Jong-Kil;Park, Yeong-Cheol
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.4
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    • pp.338-342
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    • 2020
  • Periosteal chondroma is a rare, slow-growing, benign cartilaginous tumor that develops between the periosteum and cortex, but there are no reports of multiple periosteal chondroma of the toes. A 19-year-old male presented with a palpable mass of the right fourth toe with tenderness for one year. A radiology examination revealed multiple, radio-lucent lesions with mild cortical irregularity. The magnetic resonance imaging findings were chondrogenic tumors with multiple, well-defined T1-low and T2-high signal enhanced lesions involved in the fourth proximal, middle, and distal phalanges. The tumors were removed by a surgical resection and curettage. Histologically, the tumors were proven to be periosteal chondroma.

Beyond the mouth: Uncovering non-secretory multiple myeloma through oral symptoms

  • Pedro Henrique Chaves Isaias;Fabio Wildson Gurgel Costa;Pedro Henrique Goncalves Holanda Amorim;Raul Anderson Domingues Alves da Silva;Fabrício Bitu Sousa;Karuza Maria Alves Pereira;Ana Paula Negreiros Nunes Alves;Mario Rogério Lima Mota
    • Imaging Science in Dentistry
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    • v.54 no.2
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    • pp.211-220
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    • 2024
  • Non-secretory multiple myeloma (NSMM) is a rare cancer of plasma cells characterized by the absence of detectable monoclonal M protein in the blood or urine. A 57-year-old woman presented with mandibular pain but without intraoral swelling. Imaging studies revealed multiple osteolytic lesions in her mandible and pronounced root resorption of the left mandibular second molar. Biopsy results showed atypical plasmacytoid cells positive for anti-kappa, CD138, MUM1, and CD79a antibodies, but negative for anti-lambda and CD20. These results were indicative of a malignant plasma cell neoplasm. No abnormalities were revealed by free light chain assay or by serum or urine protein electrophoresis, leading to a diagnosis of NSMM. The patient began chemotherapy in conjunction with bisphosphonate therapy and achieved remission following treatment. This case underscores the critical role of dentists in the early detection and prevention of NSMM complications, as the disease can initially present in the oral cavity.

Cowden Disease: Case Report and Review of the Literature

  • Jee Hee Son;Bo Young Chung;Min Je Jung;Yong Won Choi;Hye One Kim;Chun Wook Park
    • Annals of dermatology
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    • v.31 no.3
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    • pp.325-330
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    • 2019
  • Cowden's disease is a rare autosomal dominant, multiple hamartoma syndrome with characteristic mucocutaneous lesions. It is associated with abnormalities of the breast, thyroid, and gastrointestinal tract; and is characterized by multiple hamartomas in the gastrointestinal tract and mucocutaneous lesions such as trichilemmomas, oral papillomatosis, facial papules, and acral keratosis. A 21-year-old male patient presented with erythematous facial papules, oral mucosal papillomatosis, and punctate palmoplantar hyperkeratosis indicating a definite case of Cowden's disease. This disease derives from variable expression resulting from a mutation in the PTEN gene. Gastrointestinal endoscopy and colonoscopy revealed multiple hamartomas in the stomach and colon. On thyroid ultrasonography, several probable benign nodules were noted in the right thyroid gland. He had no pertinent family history and no other systemic findings. Further regular laboratory and image studies will be planned for our patient, as well as his family members. Sporadic Cowden's disease is rarely observed. Herein, we report a case of Cowden's disease without known family history. Dermatologists should be aware of the possibility of Cowden syndrome based on its several dermatologic findings.

Cytologic Features and Distribution of Primary Sites of Malignant Cells in Cerebrospinal Fluid - Analysis of 1,438 Specimeus - (뇌척수액내 종양세포의 원발부위 분석 및 세포학적 특징 - 총 1,438예 분석 -)

  • Kim, Yeon-Mee;Jeon, Mi-Yeong;Chi, Je-Geun
    • The Korean Journal of Cytopathology
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    • v.11 no.2
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    • pp.65-73
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    • 2000
  • Cytologlc evaluation of cerebrospinal fluid(CSF) is an effective mean for diagnosing many disorders involving the central nervous systems(CNS). One of the most important reasons for cytologic examination of CSF is to detect metastatic or primary neoplasms of the CNS. We did a retrospective study of 1,438 CSF specimens obtained between 1992 and 1996. A total of 1,205 adult and 233 pediatric CSF specimens from 947 patients were accessed at the Department of Pathology of Seoul National University Hospital and Children's Hospital, respectively. Among 1,438 CSF cytology specimens, 169 cases(11.8%, 77 patients) including 135 adult cases(59 patients) and 34 pediatric cases(18 patients) were positive for malignant cells. Diagnoses included 50 metastatic carcinomas(adult, 60; pediatric, 0); 46 malignant lymphomas(adult, 44; pediatric, 2); 21 leukemias(adult, 20; pediatric, 1); 4 retinoblastomas(adult, 0; pediatric 4); 2 rhabdomyosarcomas(adult, 0; pediatric, 2); 1 multiple myeloma(adult, 1; pediatric, 0), and 35 primary CNS neoplasms(adult, 10; pediatric, 25). The most commonly identified metastatic carcinomas in adults were adenocarcinoma. Their primary sites were the lung, gastrointestinal tract, and breast in order of frequency. The most common primary CNS neoplasm in children was medulloblastoma.

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Multiple Calcifying Fibrous Pseudotumors in the Pleura - A case report - (흉막에 생긴 다발성 석회화 섬유성 가종양 - 1예 보고 -)

  • Lee, Chang-Young;Byun, Chun-Sung;Park, In-Kyu;Chung, Kyung-Young;Hwang, Yoo-Hwa;Shim, Hyo-Sup
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.666-669
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    • 2009
  • Calcifying fibrous pseudotumors (CFP) are rare soft tissue tumors that have unique histopathologic features characterized by a dense hyalinized collagenous tissue interspersed with benign spindle cells, lymphoplasmacytic infiltrate, and psammomatous or dystrophic calcifications. We report here on a case of calcifying fibrous pseudotumors in the pleura and provide a literature review.

Pericardial mesothelioma in a dog with lymph node metastasis and chylothorax (개에서 림프절 전이와 유미흉을 동반한 심낭막 중피종 증례 보고)

  • Lee, Jeong-Ha;Lee, Su-Hyung;Go, Du-Min;Kim, Dae-Yong
    • Korean Journal of Veterinary Research
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    • v.56 no.4
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    • pp.273-276
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    • 2016
  • Pericardial mesothelioma is a rare neoplasm in dogs. This report describes a case of pericardial mesothelioma in a 13-year-old Shih Tzu that presented with a clinical history of dyspnea. Hemorrhagic pericardial effusion and chylous pleural effusion with reactive mesothelial cells were identified by radiograph and cytology. Necropsy revealed multiple round nodules throughout the pericardium and regional lymph nodes in addition to chylothorax. Histopathology revealed invasive neoplasm on the pericardial surface with metastasis to the lymph nodes. The neoplastic cells were immunopositive to both cytokeratin and vimentin. Diagnosis of pericardial mesothelioma with regional lymph node metastasis was made.

Solitary Plasmacytoma of the Sternum

  • Lee, Jung Hwa;Lee, Woo Surng;Kim, Yo Han;Kim, Jong Duk
    • Journal of Chest Surgery
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    • v.46 no.6
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    • pp.482-485
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    • 2013
  • Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the sternum are generally malignant, and solitary plasmacytomas of the sternum are very rare tumors. We present herein the case of a patient who had a primary sternal tumor with solitary plasmacytoma and no evidence of multiple myeloma.

Surgical Treatment of Multiple Lung Abscesses with Adenoid Cystic Carcinoma - A Case Report - (선양 낭포암에 의한 다발성 폐농양의 외과적 치료 - 1례 보고 -)

  • 김도형;조현민;정은규;강두영;손국희;이두연
    • Journal of Chest Surgery
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    • v.35 no.1
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    • pp.73-76
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    • 2002
  • Adenoid cystic carcinoma is a very slowly growing and directly invasive cancer. The treatment of choice is complete surgical resection but if major complications associated with remaining carcinoma occur, aggressive conservative treatment to prevent complication is able to gain long term survival even though remaining carcinoma metastases to other organs. We experienced a case of surgical treatment of uncontrollable fever that caused by multiple lung abscesses due to obstruction of left main bronchus with adenoid cystic carcinoma. The post operative course was uneventful for 4 months to now.