• 대한수의학회지
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• 제45권1호
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• pp.71-74
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• 2005

Pseudomonas aerusinosa infection was diagnosed in broiler chicks, and was submitted to the National Veterinary Research and Quarantine Service in Korea. The total mortality rate was about 1,500 birds out of 22,000 broilers. Clinically, affected birds showed clinical signs including depression and anorexia with lameness and trembling of the leg. At necropsy, the dead broilers appeared to have omphalitis, yolk sac infection, fibrinous epicarditis, and fibrinous exudates in liver with swollen hock joint. Microscopically, there were multiple necrotic foci in the liver, fibrinous exudates in the heart, and infiltration of heterophils into the joint spaces of the hock joint. Pseudomonas aerusinosa was isolated from the heart, liver and hock joint, and the isolate was named P-200. In effort to estimate the virulence of P-200, 1-day-old chicks were challenged intramuscularly and intrayolksacally with the isolate. On the basis of mortality rate, the isolate P-200 was found to be highly virulent. This is the first report of an occurrence of Pseudomonas aerusinosa infection in broilers in Korea.

• 수산해양교육연구
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• 제28권5호
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• pp.1339-1347
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• 2016

The purpose of this study was to identify factors of influencing cervical cancer and Human papilloma virus(HPV) infection preventive behavioral intention of nursing students. The research design for this study was a descriptive survey design. Data collection was done using self-report questionnaires with 218 nursing students in B city from November 30 to 15 December, 2015. Data were analyzed using percentage, mean, standard deviation, t-test, ANOVA, Pearson's correlation analysis and multiple regression with SPSS Win 21.0 program. The significant factors of cervical cancer and HPV infection preventive behavioral intention was cervical cancer knowledge(${\beta}=.246$, p<.001), health belief about HPV vaccination(${\beta}=-.223$, p<.001), HPV vaccination(${\beta}=.173$, p=.008), and Gynecological Disease History(${\beta}=.145$, p=.026). And these factors explained 15.4% of the variance in the cervical cancer and HPV Infection preventive behavioral intention. In conclusion, the results of this study indicated that it's a need to develop the effective education program in addition to knowledge improvement on HPV and cervical cancer for nursing students.

• 한국동물위생학회지
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• 제44권1호
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• pp.35-43
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• 2021

Rabbit infectious hemorrhagic fever has been reported in rabbits worldwide. The disease is also frequently reported on Korean rabbit farms, and the pathological study of 9 rabbits on such disease-occurring farms was attempted to identify the pathogen. Clinical signs were torticollis and ear ulceration. Most rabbit died with bloody nasal discharges. At necropsy, multiple hemorrhages and inflammation were observed in heart, lung, liver and uterus. The main histopathologic features were hemorrhagic suppurative meningoencephalitis, fibrinous bronchointerstitial pneumonia, bacteremia, liver cell necrosis, multifocal hemorrhages in kidney and disseminated intravascular coagulopathy. The viral VP60 gene of RHDV was identified by Reverse Transcriptase PCR. Pasteurella multocida organisms were cultured, identified by biochemical test and serotyped as A by multiplex capsular typing PCR. In conclusion, the fatal hemorrhagic disease was due to combined infection with both RHDV and P. multocida in rabbits. To our knowledge, this is the first case report about co-infection with both RHDV and P. multocida in rabbits in Korea.

• 한국학교보건학회지
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• 제35권3호
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• pp.75-83
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• 2022

Purpose: This study aimed to identify factors affecting COVID-19 infection prevention behaviors among teachers and administrative staff of elementary schools. Methods: A total of 204 participants, who were elementary school teachers and administrative staff, completed a pack of self-report questionnaires. The variables were COVID-19-related knowledge and COVID-19 infection prevention behaviors. The collected data were analyzed using descriptive statistics, t-test, 𝑥², Pearson's correlation coefficient, and multiple regression. Results: The participants' COVID-19-related knowledge was 3.67±0.85 and their COVID-19 prevention behaviors were 4.60±0.36. COVID-19 prevention behaviors had a positive relationship (r=.15, p=.031) with COVID-19-related knowledge. Factors affecting COVID-19 prevention behaviors were occupation (administrative staff), age, sex (male), COVID-19-related knowledge, and subjective health (good). Conclusion: It is expected that findings of the study will be used as essential data for developing strategies promoting school health. Considering the results, there is a need to create effective interventions that can increase COVID-19 infection prevention behaviors and COVID-19-related knowledge of teachers and administrative staff of elementary schools.

• IMMUNE NETWORK
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• 제22권4호
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• pp.32.1-32.20
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• 2022

Sjögren syndrome (SS) is a chronic autoimmune disorder that primarily targets the salivary and lacrimal glands. The pathology of these exocrine glands is characterized by periductal focal lymphocytic infiltrates, and both T cell-mediated tissue injury and autoantibodies that interfere with the secretion process underlie glandular hypofunction. In addition to these adaptive mechanisms, multiple innate immune pathways are dysregulated, particularly in the salivary gland epithelium. Our understanding of the pathogenetic mechanisms of SS has substantially improved during the past decade. In contrast to viral infection, bacterial infection has never been considered in the pathogenesis of SS. In this review, oral dysbiosis associated with SS and evidence for bacterial infection of the salivary glands in SS were reviewed. In addition, the potential contributions of bacterial infection to innate activation of ductal epithelial cells, plasmacytoid dendritic cells, and B cells and to the breach of tolerance via bystander activation of autoreactive T cells and molecular mimicry were discussed. The added roles of bacteria may extend our understanding of the pathogenetic mechanisms and therapeutic approaches for this autoimmune exocrinopathy.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권1호
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• pp.87-91
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• 2001

On patients with disorder of hematopoiesis such as leukemia, aplastic anemia, MDS(Myelodisplastic Syndromes), removal of infectious foci prior to the BMT(Bone Marrow Transplantation) is a necessity and what is more, there is no sufficient time to control the infections because the chemotherapy for BMT should be started as soon as possible. And the transfusion should be minimized to prevent the alloimmunization. In those reasons, oral & maxillofacial surgeons are often in need of multiple extractions, and should take into consideration the possibility of complications after multiples extractions such as infection, severe bleeding because those situations can be fatal on patients with disorder of hematopoiesis. We present our experience in multiple extractions on 30 patients with disorder of hematopoiesis referred from Catholic Hematopoiesis Stem Cell transplantation Center at St. Mary's Hospital, The Catholic University of Korea.

• 디지털융복합연구
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• 제20권3호
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• pp.359-366
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• 2022

본 연구는 COVID-19 유행상황에서 간호대학생의 윤리적 의사결정, 도덕적 민감성 및 감염관리 수행도와의 관계를 파악하여 간호대학생의 감염관리 수행도를 높이기 위한 중재방법의 기초자료를 제공하기 위함이다. 간호대학생 3,4학년을 대상으로 구조화된 설문지를 이용하여 일반적 특성, 전공 관련 특성, 윤리적 의사결정, 도덕적 민감성 및 수행도를 조사하였다. 자료분석은 IBM SPSS21.0 프로그램을 이용하여 기술통계, Indepentent t-test, One-way ANOVA, Pearson's correlation coefficient, Stepwise Multiple regression anlaysis를 하였다. 본 연구결과 COVID-19 감염관리 수행도에 영향을 미치는 요인으로 윤리적 의사결정에서 선행의 원칙, 도덕적 민감성에서 갈등과 환자중심간호로 나타났다. 앞으로 신종감염병이 출현할 가능성이 높은 상황에서 예비의료인인 간호대학생의 감염관리 수행도를 향상시키기 위해서는 환자중심의 간호윤리를 강화할 수 있는 실무중심의 융복합적인 교육프로그램을 개발하는 것이 필요하다.

• Journal of Korean Neurosurgical Society
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• 제53권5호
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• pp.312-315
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• 2013

Aspergillosis in the central nervous system (CNS) is a very rare disease in immune-competent patients. There was a case of a healthy man without a history of immune-compromised disease who had invasive aspergillosis with unusual radiologic findings. A 48-year-old healthy man with diabetes mellitus, presented with complaints of blurred vision that persisted for one month. Brain magnetic resonance imaging (MRI) showed multiple nodular enhancing lesions on the right cerebral hemisphere. The diffusion image appeared in a high-signal intensity in these areas. Cerebrospinal fluid examination did not show any infection signs. An open biopsy was done and intraoperative findings showed grayish inflammatory and necrotic tissue without a definitive mass lesion. The pathologic result was a brain abscess caused by fungal infection, morphologically aspergillus. Antifungal agents (Amphotericin B, Ambisome and Voriconazole) were used for treatment for 3 months. The visual symptoms improved. There was no recurrence or abscess pocket, but the remaining focal enhanced lesions were visible in the right temporal and occipital area at a one year follow-up MRI. This immune-competent patient showed multiple enhancing CNS aspergillosis in the cerebral hemisphere, which had a good outcome with antifungal agents.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5781-5785
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• 2014

Background: As in other developing countries, cervical cancer is the most frequent gynecologic malignancy in Indonesia. Persistent high risk genotypes of human papillomavirus (HPV) that infect the cervical tissue have been established as the etiology of cervical cancer. This study aimed to explore the profile of cervical cancer patients and the infected HPV genotypes at Dr. Hasan Sadikin General Hospital-Bandung. Materials and Methods: During the year 2010, 554 cervical cancer patients were registered. In a subset of the patients during July - November 2010, 40 randomized fresh biopsies were tested for HPV genotype after obtained informed consent. The distribution of HPV genotypes and the association to risk factors were analysed. Results: The result showed that 62.5% of the tested biopsies were infected by multiple HPV infections, with HPV-16 found in most of the cervical cancer patients (90%). Marriage at age younger than 16 years old was statistically significant in relation to multiple HPV infection (p=0.003), but not parity more than three times (p=0.59). Conclusions: Although high paritiy in our study was not associated with multiple HPV infection, good family planning programs and reproductive health education need to be emphasized in Indonesia as high parity and marriage at young age might increase the chance of cervical cancer development.

• 한국학교보건학회지
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• 제37권1호
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• pp.1-11
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• 2024

Purpose: The purpose of the study was to conduct a descriptive survey to examine the knowledge, infection prevention behaviors, and health beliefs regarding COVID-19 and to identify factors that influence infection prevention behaviors in elementary and middle school students based on the Health Belief Model. Methods: The study included 388 elementary and middle school students in Seoul, Gyeonggi, and Jeonbuk provinces. Data were collected from September 1 to September 15, 2023. The questionnaire consisted of 10 questions about COVID-19 knowledge, 13 questions about infection prevention behaviors, and 15 questions about health beliefs. The collected data were subjected to multiple hierarchical regression analyses. The cronbach's α of infection prevention behaviors was 0.83, the KR-20 of COVID-19 related knowledge was 0.68, and the Cronbach's α of COVID-19 related health beliefs was 0. 78. Results: In Model 1, females showed higher levels of infection prevention behaviors than males (β=.14, p=.006) and middle school students showed lower levels of infection prevention behaviors than elementary school students (β=-.10, p=.037). In Model 2, among COVID-19-related health beliefs, barriers had a significant negative effect on infection prevention behaviors (β=-.20, p<.001) and cues to action had a significant positive effect on infection prevention behaviors (β=.14, p=.037), indicating that lower barriers and higher cues to action were associated with higher levels of infection prevention behaviors. Conclusion: The results showed that prevention behaviors were associated with lower barriers and higher cues to action among COVID-19 health beliefs. Elementary and middle school students in Korea spend a lot of time in groups at private academies or school, which are closed spaces with poor ventilation, making them vulnerable to new infectious diseases such as COVID-19. Unlike adults, infectious diseases can have serious impact on their mental and social health. Therefore, it is necessary for schools to provide accurate and timely health education about COVID-19 to increase cues to action for elementary and middle school students in order to improve their infection prevention behaviors.