• Title/Summary/Keyword: Multiple alignment

Search Result 270, Processing Time 0.03 seconds

The Predictable Factors of the Postoperative Kyphotic Change of Sagittal Alignment of the Cervical Spine after the Laminoplasty

  • Lee, Jun Seok;Son, Dong Wuk;Lee, Su Hun;Kim, Dong Ha;Lee, Sang Weon;Song, Geun Sung
    • Journal of Korean Neurosurgical Society
    • /
    • 제60권5호
    • /
    • pp.577-583
    • /
    • 2017
  • Objective : Laminoplasty is an effective surgical method for treating cervical degenerative disease. However, postoperative complications such as kyphosis, restriction of neck motion, and instability are often reported. Despite sufficient preoperative lordosis, this procedure often aggravates the lordotic curve of the cervical spine and straightens cervical alignment. Hence, it is important to examine preoperative risk factors associated with postoperative kyphotic alignment changes. Our study aimed to investigate preoperative radiologic parameters associated with kyphotic deformity post laminoplasty. Methods : We retrospectively reviewed the medical records of 49 patients who underwent open door laminoplasty for cervical spondylotic myelopathy (CSM) or ossification of the posterior longitudinal ligament (OPLL) at Pusan National University Yangsan Hospital between January 2011 and December 2015. Inclusion criteria were as follows : 1) preoperative diagnosis of OPLL or CSM, 2) no previous history of cervical spinal surgery, cervical trauma, tumor, or infection, 3) minimum of one-year follow-up post laminoplasty with proper radiologic examinations performed in outpatient clinics, and 4) cases showing C7 and T1 vertebral body in the preoperative cervical sagittal plane. The radiologic parameters examined included C2-C7 Cobb angles, T1 slope, C2-C7 sagittal vertical axis (SVA), range of motion (ROM) from C2-C7, segmental instability, and T2 signal change observed on magnetic resonance imaging (MRI). Clinical factors examined included preoperative modified Japanese Orthopedic Association scores, disease classification, duration of symptoms, and the range of operation levels. Results : Mean preoperative sagittal alignment was $13.01^{\circ}$ lordotic; $6.94^{\circ}$ lordotic postoperatively. Percentage of postoperative kyphosis was 80%. Patients were subdivided into two groups according to postoperative Cobb angle change; a control group (n=22) and kyphotic group (n=27). The kyphotic group consisted of patients with more than $5^{\circ}$ kyphotic angle change postoperatively. There were no differences in age, sex, C2-C7 Cobb angle, T1 slope, C2-C7 SVA, ROM from C2-C7, segmental instability, or T2 signal change. Multiple regression analysis revealed T1 slope had a strong relationship with postoperative cervical kyphosis. Likewise, correlation analysis revealed there was a statistical significance between T1 slope and postoperative Cobb angle change (p=0.035), and that there was a statistically significant relationship between T1 slope and C2-C7 SVA (p=0.001). Patients with higher preoperative T1 slope demonstrated loss of lordotic curvature postoperatively. Conclusion : Laminoplasty has a high probability of aggravating sagittal balance of the cervical spine. T1 slope is a good predictor of postoperative kyphotic changes of the cervical spine. Similarly, T1 slope is strongly correlated with C2-C7 SVA.

고감도 레이저 간섭계를 이용한 미소 진동 진폭의 정밀측정 (Ultrasensitive laser interferometer for precision measurement of small vibration displacement)

  • 서상준
    • 대한기계학회논문집
    • /
    • 제12권3호
    • /
    • pp.440-449
    • /
    • 1988
  • 본 연구에서는 미소한 진동진폭의 정밀한 측정을 위해 비교적 광선정렬(opti- cal alignment)이 쉽고 광손실이 적으며 국소부위의 진동측정이 가능한 다중반사계를 Michelson간섭계에 도입하였다.미소 진동진폭의 정밀한 값을 결정하기 위해서는 간 섭신호를 측정하여 간섭무늬 보간법과 곡선 맞춤법을 이용하는 방법이 있다. 전자는 간단한 계산과 시간을 절약할 수 있는 반면 후자는 복잡한 계산으로 인해 많은 시간이 소요된다. 그러나 정밀계측장비의 교정에서와 같이 경우에 따라서는 많은 시간과 노 력이 소요되더라도 정밀한 측정결과를 얻어야할 필요가 있기 때문에 이들 두가지 방법 의 정밀도를 확인하기 위해 컴퓨터에 의한 모의실험을 수행하였다.

Cloning and Sequence Analysis of a Levansucrase Gene from Rahnella aquatilis ATCC15552

  • Kim, Hyun-Jin;Yang, Ji-Young;Lee, Hyeon-Gye;Cha, Jae-Ho
    • Journal of Microbiology and Biotechnology
    • /
    • 제11권4호
    • /
    • pp.693-699
    • /
    • 2001
  • An intracellular levansucrase gene, lscR from Rahnella aquatilis ATCC 15552, was cloned and its nucleotide sequence was determined. Nucleotide sequence analysis of this gene revealed a 1,238 bp open reading frame coding for a protein of 415 amino acids. The levansucrase was expressed by using a T7 promoter in Escherichia coli BL21 (DE3) and the enzyme activity was detected in the cytoplasmic fraction. The optimum pH and temperature of this enzyme for levan formation was pH 6 and $30^{\circ}C$, respectively. The deduced amino acid sequence of the lscR gene showed a high sequence similarity (59-89%) with Gram-negative levansucrses, while the level of similarity with Gram-positive enzymes was less than 42%. Multiple alignments of levansucrase sequences reported from Gram-negative and Gram-positive bacteria revealed seven conserved regions. A comparison of the catalytic properties and deduced amino acid sequence of lscR with those of other bacterial levansucrases strongly suggest that Gram-negative and Gram-positive levansucrases have an overall different structure, but they have a similar structure at the active site.

  • PDF

3-사용자 X 채널에서 다중안테나를 이용한 완전 간섭정렬기법 (Interference Alignment based on 3-user X Channel with Multiple Antennas)

  • 박성호;고영채
    • 한국방송∙미디어공학회:학술대회논문집
    • /
    • 한국방송공학회 2010년도 추계학술대회
    • /
    • pp.217-218
    • /
    • 2010
  • 본 논문은 3-사용자 X 채널 상황에서 다중안테나를 이용하여 간섭을 완벽하게 제어하는 기법에 대해 제안한다. 기존에 제안된 방식이 빔포밍(beamforming) 벡터를 다수의 채널을 사용하여 만드는데 따른 비현실적인 문제와 간섭을 완벽하게 제어하기 위한 무한한 채널 사용의 필요성에 따른 문제점을 본 논문에서는 다중안테나를 이용하여 공간적 특성을 이용한 빔포밍 벡터를 형성하고 채널의 확장 없이 간섭을 완벽히 제어하도록 하는 시스템을 제안한다. 제안한 시스템은 9개의 DOF(Degrees of freedom)을 얻을 수 있음을 모의실험 결과를 통해 확인할 수 있다.

  • PDF

Nanotransfer Printing for Large-Scale Integrated Nanopatterns of Various Single-Crystal Organic Materials

  • 백장미;박경선;성명모
    • 한국진공학회:학술대회논문집
    • /
    • 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
    • /
    • pp.361.2-361.2
    • /
    • 2016
  • The manufacture of organic electronic circuits requires effective heterogeneous integration of different nanoscale organic materials with uniform morphology and crystallinity in a desired arrangement on a substrate. Herein, we present a new direct printing method, which enables monolithic integration of crystalline nanowire arrays with a diverse range of organic materials. In this method, we use a nanoscale patterned soft mold, which contains an assembly of simple nanoline patterns but, in combination with droplet of various organic inks, can produce a large-scale integration of various nanopatterns with multiple kinds of organic materials. The morphology of organic nanowires can controlled by nanoconfinement in nanoline of mold. And mutual alignment of nanopatterns can be controlled by adjusting the ink droplet size, number of droplets, ink deposition locations.

  • PDF

베이지안 네트워크 기반의 변형된 침입 패턴 분류 기법 (Modificated Intrusion Pattern Classification Technique based on Bayesian Network)

  • 차병래;박경우;서재현
    • 인터넷정보학회논문지
    • /
    • 제4권2호
    • /
    • pp.69-80
    • /
    • 2003
  • 프로그램 행위 침입 탐지 기법은 데몬 프로그램이나 루트 권한으로 실행되는 프로그램이 발생시키는 시스템 호출들을 분석하고 프로파일을 구축하여 변형된 공격을 효과적으로 탐지한다. 본 논문에서는 베이지안 네트워크와 다중 서열 정렬을 이용하여 여러 프로세스의 시스템 호출간의 관계를 표현하고, 프로그램 행위를 모델링하여 변형된 이상 침입 행위를 분류함으로써 이상행위를 탐지한다. 제안한 기법을 UNM 데이터를 이용한 시뮬레이션을 수행하였다.

  • PDF

효율적인 복수서열정렬 최적화기법 (An efficient optimization method for multiple sequence alignment)

  • 김진;정우철;엄상용
    • 한국정보과학회:학술대회논문집
    • /
    • 한국정보과학회 2003년도 봄 학술발표논문집 Vol.30 No.1 (B)
    • /
    • pp.368-370
    • /
    • 2003
  • 단백질들의 복수서열정렬은 단백질 서열간의 관계를 유추할 수 있는 유용한 도구이다. 최적화된 복수서열정렬을 얻기 위해 사용되는 가장 유용한 방법은 dynamic programming이다. 그러나 dynamic programming은 특정한 비용함수를 사용할 수 없기 때운에 특별한 경우 최적의 복수서열정렬을 제공하지 못하는 문제점이 있다. 우리는 이러한 문제점을 해결하기 위하여 부분정렬개선기법을 사용한 알고리즘을 제안하였으며, 이 알고리즘이 dynamic programming의 문제점을 효과적으로 해결함을 보였다.

  • PDF

자연모사를 통한 미세 고분자 포토닉 구조의 구면배열에 관한 연구 (Spherical arrangement of biomimetic polymer photonic structures)

  • 정기훈
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2007년도 춘계학술대회A
    • /
    • pp.403-404
    • /
    • 2007
  • Compound eyes in nature present intriguing topics in physiological optics due to their unique optical scheme for imaging. For example, a bee's eye has thousands of integrated photonic units called ommatidia spherically arranged along a curvilinear surface so that each unit points in a different direction. The omni-directionally arranged ommatidium collects incident light with a narrow range of angular acceptance and independently contributes to the capability of wide field-of-view (FOV) detection. Artificial implementation of compound eyes has attracted a great deal of research interest because the wide FOV exhibits a huge potential for medical, industrial, and military applications. So far, imaging with a FOV over $90^{\circ}$ has been achieved only with fisheye lenses which rely on bulky and expensive multiple lenses and require stringent alignment. In this talk, we will discuss about the spherical 3D arrangement of the photonic structures of biologically inspired artificial compound eyes in a small form-factor to have and the functional and anatomical similiarity with natural compound eyes.

  • PDF

Multiplex PCR을 이용한 Extended-Spectrum β-Lactamase 생성 Escherichia coli와 Klebsiella pneumoniae의 Quinolone 내성 qnr유전자 검출 (Multiplex PCR for Detection of Quinolone Resistance qnr Genes in Extended-Spectrum β-Lactamase Producing Escherichia coli and Klebsiella pneumoniae)

  • 양병선
    • 대한임상검사과학회지
    • /
    • 제39권3호
    • /
    • pp.161-166
    • /
    • 2007
  • To develop a rapid and reliable single-tube-based PCR technique for detection simultaneously the quinolone resistance qnrA, qnrB and qnrS genes. After multiple alignment, primers were designed to detect known qnr variants. I was used for A total of 43 extented-spectrum ${\beta}$-lactamases (ESBLs) producing Escherichia coli and Klebsiella pneumoniae isolated from university hospital were tested for screening, as with qnr genes. In optimized conditions, all positive controls confirmed the specificity of the PCR primers. Out of 43 isolates, qnrA genes were detected 19 (44.2%), qnrB genes 5 (11.7%), qnrS genes 15 (34.9%) and 8 (18.6%) isolates were not detected. I report here a fast and reliable technique for rapid screening of qnr positive strains to be used for epidemiological surveys.

  • PDF

3D scanner's measurement path establishment automation by robot simulator

  • Jang, Pyung-Su;Lee, Sang-Heon;Chang, Min-Ho
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 제어로봇시스템학회 2005년도 ICCAS
    • /
    • pp.2179-2182
    • /
    • 2005
  • Recently, optical 3D scanners are frequently used for inspection of parts, assembly and manufacturing tooling. One of the advantages is being able to measure a large area fast and accurately. Owing to recent advances in high-resolution image sensing technology, high power illumination technology, and high speed microprocessors, the accuracy and resolution of optical 3D scanners are being improved rapidly. In order to measure the entire geometry of objects, multiple scans have to be performed in various setups by moving either the objects or the scanner. This paper introduces novel methods to measure the entire geometry of objects by automatically changing the setups and then aligning the scanned data in a single coordinate system.

  • PDF