• Smart Media Journal
• /
• v.7 no.4
• /
• pp.79-89
• /
• 2018

In recent years, falls among elderly people have gained serious attention as a major cause of injuries. Falls often lead to fatal consequences due to lack of prompt response and rescue. Therefore, a more accurate fall detection system and an effective feature extraction technique are required to prevent and reduce the risk of such incidents. In this paper, we proposed an efficient feature extraction technique based on multiple sliding windows and validated it through a series of experiments using supervised learning algorithms. The experiments were conducted using the public datasets obtained from tri-axial accelerometers. The results depicted that extraction of the feature from adjacent sliding windows led to high accuracy in supervised machine learning-based fall detection. Also, the experiments conducted in this study suggested that the best accuracy can be achieved by keeping the window size as small as 2 seconds. With the kNN classifier and dataset from wearable sensors, the experiments achieved accuracy rates of 94%.

• Asia Marketing Journal
• /
• v.21 no.3
• /
• pp.1-20
• /
• 2019

The present study investigates how consumers' construal level affects their variety seeking behavior when choosing multiple items simultaneously. Especially the authors focus on the perceptual level at which variety seeking takes place and propose that variety seeking can take place not only at brand level but also at category or subcategory level. Categorical variety seeking refers to diversification of one's choices over multiple brands not within the same category but across multiple categories. Building on construal level theory, the authors expected that people engaging in higher-level construals tend to subcategorize the choice set and distribute their choices across more subcategories and designed four experiments to test the related hypotheses. The experimental results showed that consumers' construal level can affect the level at which variety seeking takes place and those with higher construal level tend to choose options seemingly more dissimilar to each other.

• BMB Reports
• /
• v.45 no.11
• /
• pp.629-634
• /
• 2012

The human glycoprotein, stanniocalcin 2 (STC2) plays multiple roles in several tumor types, however, its function and clinical significance in hepatocellular carcinoma (HCC) remain unclear. In this study, we detected STC2 expression by quantitative real-time PCR and found STC2 was upregulated in HCC tissues, correlated with tumor size and multiplicity of HCC. Ectopic expression of STC2 markedly promoted HCC cell proliferation and colony formation, while silencing of endogenous STC2 resulted in a reduced cell growth by cell cycle delay in G0/G1 phase. Western blot analysis demonstrated that STC2 could regulate the expression of cyclin D1 and activate extracellular signal-regulated kinase 1/2 (ERK1/2) in a dominant-positive manner. Transwell chamber assay also indicated altered patterns of STC2 expression had an important effect on cell migration. Our findings suggest that STC2 functions as a potential oncoprotein in the development and progression of HCC as well as a promising molecular target for HCC therapy.

• Korean Journal of Social Welfare
• /
• v.63 no.2
• /
• pp.133-154
• /
• 2011

This study aimed to examine the relationship between the expectation of independent life in old age and intergenerational downward transfer of Korean old people. It was focused on old people who did not live with their adult children by using the raw data of "2008 the Korean study of Welfare Services for the Elderly". The data were analysed by multiple regression analysis. The results showed the degree of the expectation of independent life in old age had positive effect on economic and service downward transfer of old people. Concretely, the degree of the expectation of economic and physical independence had positive effect on economic and service downward transfer of old people. The degree of the expectation of emotional independence had positive effect on service downward transfer of old people, while it had no effect on economic downward transfer.

• Journal of Family Resource Management and Policy Review
• /
• v.21 no.2
• /
• pp.95-117
• /
• 2017

The purpose of this study was to examine the level of anxiety about economic change in middle-aged and elderly people and to analyze the factors that influence this anxiety. The data, derived from Korean General Social Survey(KGSS) were collected from Survey Research Center of Sung Kyun Kwan University. The samples included 821 people over the age of 40, including 529 middle-aged people who were from 40 to 59, and elderly people who were over 60. Multiple regression analysis was used to analyze the research model. The findings from the analysis showed that age and subjective economic status had crucial effects on the entire group's anxiety about unemployment and poverty, housing prices, financial markets, and economic recession in the older life. For the middle-aged group, age in particular had crucial effects on all the components of its anxiety about economic change. For the elderly group, geographical region was the most critical factor that affected its anxiety about economic change, the elderly people who were living in metropolitan area and towns had more anxiety than those who were living in rural areas. In particular, region was the only factor that affected the elderly group's anxiety about financial markets, and economic recession. These results showed that specific age of middle-aged and elderly people had the crucial effects while their sex, educational level, and the employment status of their spouse had no effects on their anxiety about economic change. Objective economic indices such as their earned-income and other income including savings and pensions had no effects on their anxiety level. While as noted above subjective economic indices such as their standard of living compared with their parents, projected economic status, and level of socio-economic success had an effect on anxiety about economic change.

• Journal of Preventive Medicine and Public Health
• /
• v.45 no.4
• /
• pp.211-218
• /
• 2012

Objectives: The objective of this study was to identify the differences in obesity rates among people with and without disabilities, and evaluate the relationship between obesity rates and the existence of disabilities or characteristics of disabilities. Methods: Mass screening data from 2008 from the National Disability Registry and National Health Insurance (NHI) are used. For analysis, we classified physical disability into three subtypes: upper limb disability, lower limb disability, and spinal cord injury. For a control group, we extracted people without disabilities by each subtype. To adjust for the participation rate in the NHI mass screening, we calculated and adopted the weight stratified by sex, age, and grade of disability. Differences in obesity rates between people with and without disabilities were examined by a chi-squared test. In addition, the effect of the existence of disabilities and grade of disabilities on obesity was examined by multiple logistic regression analysis. Results: People with disabilities were found to have a higher obesity rate than those without disabilities. The obesity rates were 35.2% and 35.0% (people with disabilities vs. without disabilities) in the upper limb disability, 44.5% and 34.8% in the lower limb disability, 43.4% and 34.6% in the spinal cord injury. The odds for existence of physical disability and grade of disability are higher than the nondisabilities. Conclusions: These results show that people with physical disability have a higher vulnerability to obesity.

• Journal of Microbiology and Biotechnology
• /
• v.31 no.11
• /
• pp.1508-1518
• /
• 2021

Hsa_circ_0001947 is associated with multiple cancers, but its function in non-small cell lung cancer (NSCLC) is ambiguous and needs further research. The targeting relationship among circ_0001947, miR-661, and downstream of tyrosine kinase 7 (DOK7) was predicted by database and further verified by dual-luciferase reporter assay, while their expressions in cancer tissues and cells were detected by quantitative real-time polymerase chain reaction (qRT-PCR). After transfection, cell biological behaviors and expressions of miRNAs, miR-661 and DOK7 were determined by cell function experiments and qRT-PCR, respectively. Circ_0001947 was low-expressed in NSCLC tissues and cells. Circ_0001947 knockdown intensified cell viability and proliferation, induced cell cycle arrest at S phase, suppressed apoptosis and evidently enhanced miR-510, miR-587, miR-661 and miR-942 levels, while circ_0001947 overexpression did the opposite. MiR-661 was a target gene of circ_0001947 that participated in the regulation of circ_0001947 on cell biological behaviors. Furthermore, DOK7, the target gene of miR-661, partly participated in the regulation of miR-661 on cell viability. Hsa_circ_0001947 acts as a sponge of miR-661 to repress NSCLC development by elevating the expression of DOK7.

• Korean Journal of Social Welfare
• /
• v.54
• /
• pp.35-64
• /
• 2003

This study is to explore experience on the inter-organizational linkages for vocational rehabilitation of people with psychiatric disabilities and to find out predictors affecting the linkages. This study used triangulation a way as to combine the advantages of both the qualitative and the quantitative approach. The qualitative approach is based on grounded theory by Strauss & Cobin. The quantitative research used the samples of 122 organizations, and was analyzed by multiple regression & logistic regression. The results are as follows. First, as results of in-depth interview, interviewees perceived linkage experience as 'turning the eyes on the other organization in community', namely 'the pursue of collaboration'. This concept is classified four types: initiative, cooperative, authoritative and passive type. Second, according to Tobin(1986)'s five phase of the closeness of inter-organizational linkages, our linkages were found to be in third phase, "coordination". Finally, predictors of the attempt of having linkages & linkage strengthening were analyzed by logistic regression & multiple regression. 'The experience of professional training on people with psychiatric disabilities' and 'the resource dependency' have statistically significant relation with the attempt to have linkages. 'The length of current service', 'the experience of professional training on people with psychiatric disabilities', and 'recognition about other organizational activities' are significantly related to strengthening linkage. Based on the results of this study, alternatives for promoting inter-organization linkages for vocational rehabilitation of people with psychiatric disabilities were proposed.

• Journal of agricultural medicine and community health
• /
• v.37 no.4
• /
• pp.246-257
• /
• 2012

Objectives: To compare the self-rated health in chronic disease patients with depression, chronic disease patients, and depression patients, and to observe the related factors to the self-rated health of people age 65 and older. Methods: The subjects were 2,549 elderly people, over 65 years old in Busan Metropolitan City who participated in 2009 community health survey. Association between self-rated health and general characteristics, life style and disease status were observed. Depressive symptoms were measured using the Centre for Epidemiologic Studies Depression Scale (CES-D). Analysis of complex sample was done with SAS (ver. 9.2), using ${\chi}^2$-test and multiple logistic regression. Results: Among total 2,549, there were 740 normal people (29.8%), 50 people with depression (1.8%), 1,495 people with other chronic diseases (58.2%), and 264 people with the comobidity of depression and other chronic diseases (10.1%). Good self-related health accounted for 20.3% for the whole, 33.4% for normal, 16.7% for chronic disease, 16.1% for depression, and 3.2% for chronic diseases with depression. Disease, gender, education, income, alcohol drinking, regular exercise and regular walking were independent factors associated with the good self-related health. Conclusions: It is suggested that when the chronic disease control program for the elderly is developed, depression care should be considered along with the program. This program should be given priority to the women and the vulnerable classes and should also be related to the regular walking.

• Korean Institute of Interior Design Journal
• /
• v.21 no.1
• /
• pp.3-10
• /
• 2012

There is a growing awareness that physical barriers affect the level of independence of people with disabilities. Many researchers insist that barrier free design could influence independence living and quality of life of the disabled. The purpose of this study is to find out the effects of accessible design features of house and public facilities on quality of life of disabled people. A total of 189 questionnaires from the disabled who visited public welfare facilities was analyzed. In order to find out what variables among accessible features in housing and public spaces impact quality of life, multiple regression analysis was carried using SPSS 14. The results showed that accessible designs significantly influence quality of life of the disable. The main reason in which the disabled have difficulties when they move outside is a lack of accessible amenities and facilities. Particularly in house design, accessible main entrance route and accessible main entrance door, and removal of floor level significantly affects quality of life of the disabled. For public spaces, accessible main entrance and installation of ramp or removal of floor levels of main entrance and corridor increase quality of life people with disabilities. This paper suggested that the improvement in housing and public space, in which regulation or bylaws do not specify, should be made to increase accessibility for life quality of the disabled.