• Journal of Korean Foot and Ankle Society
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• v.23 no.4
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• pp.173-182
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• 2019

Purpose: This study determined if anterior talofibular ligament (ATFL)/superior extensor ankle retinaculum (SEAR) thicknesses are related to dynamic balance in individuals with chronic ankle instability (CAI). Materials and Methods: The subjects were 14 males and 15 females (age=24.52±3.46 years). Ankle instability was assessed using the Cumberland Ankle Instability Tool (CAIT) with a cut off score of 25 to define two groups. SonoSite MTurbo (Fugifilm Sonosite, Inc.) musculoskeletal ultrasound (MSKUS) unit was used to assess ATFL and SEAR thicknesses. Dynamic balance was measured with the Y Balance Test (YBT) and two NeuroCom balance tests. Results: There were no significant differences in the average ATFL thickness between stable and unstable ankles in those subjects with CAI (0.25±0.03 cm and 0.21±0.05 cm, respectively) or in the SEAR thickness (0.09±0.04 cm and 0.10±0.03 cm, respectively). There were also no significant differences in the right and left ATFL thicknesses (0.23±0.07 cm and 0.21±0.04 cm, respectively) or the SEAR thicknesses (0.09±0.01 cm and 0.09±0.01 cm, respectively) in those without CAI. There were no differences between limbs in composite scores on YBT in those with CAI (p=0.35) and those without CAI (p=0.33). There was a moderate correlation between the left SEAR thickness and the large forward/backward perturbations on the NeuroCom (Natus) motor control test (r=0.51, p=0.006 and r=0.54, p=0.003, respectively). Conclusion: There were no differences in the ATFL/SEAR thicknesses or balance measures between or within the groups, likely because CAI is multi-factorial and related to mechanisms other than tissue changes alone. More sensitive technology and a better definition of the measurement process may provide more definitive results.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5025-5032
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• 2012

The purpose of this study is to compare the working memory and the phonological awareness between Children with multi-cultural families and general families. The research subjects were 15 multi-cultural and 15 general primary school students who were attending 1st-3rd grade in D city. Working memory tested K-TTFC-2 by standardized tool. Phonological awareness abilities was considering the age of the subjects, tested phoneme awareness. Data process was conducted by t -test and frequency test in SPSS program. The results were as follows. First, working memory comparison of both groups showed significant differences. Especially had significant difference in chapter 1, chapter 4. Second, comparison of phonological awareness between both groups showed significant statistic differences. Third, the Phonological awareness comparison of both groups showed that there are differences in sound matching(word medial coda), substituting middle sound in monosyllabic words, phoneme switching. This research result is considered that can be used as the fundamental data for the development of the therapy data considering the working memory and the phonological awareness of children with multi-cultural families.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.3 no.2
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• pp.19-27
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• 2008

Objective : The purpose of this study is to investigate the results of korean traditional conservative therapy for thoraco-lumbar compression fracture and it's recovery rate and different result in accordance with sex, age, medical history. Method : We studied about 35 cases who were admitted to Jaseng Hospital of Oriental Medicine with diagnosis of 'Thoraco lumbar compression fracture' with X-ray examination. Result : Out of 35 patients 31 patients discharged with satisfying results. Most of the compression fracture occurred in age of $60{\sim}70$. And the single fractured patients recovered more easily than the multi-level fractured patients. It didn't affect the results whether the patient had another vertebral disease(such as Herniated intervertebral disc or osteoporosis) or not. And most of the patients who had vertebral compression fracture visited the western medicine hospital first. Conclusions : We analyzed the tendency of the patients who had vertebral compression fracture, and concluded that the conservative Korean traditional therapy is an effective means of treatment for the patients who have thoraco-lumbar compression fracture.

• Journal of Korean Physical Therapy Science
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• v.7 no.1
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• pp.321-331
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• 2000

The purpose of this study was to investigate the difference of body composition and IADL of between male elder and female elder. (This study consisted of elder male(n=10) and elder female(n=10),) The mean age of elder male and female was 67.20, 67.50 years. The data were analyzed with t-test, using SPSS PC+ program. Body composition was measured using Inbody 2.0(seoul, korea) of segmental multi-frequency impedance analyzer technique. IADL was measured with Philadelphia Geriatric Center IADL. The result of this study were the following: 1. The difference of Body composition 1) The %fat of elder female was significantly(p<0.05) higher than elder male by 11.48%. 2) The fat mass(kg) of elder female was significantly(p<0.05) higher than elder male by 6.28kg. 3) The free fat mass(kg) of elder male was significantly(p<0.05) higher than elder female by 9.03kg. 4) The muscle mass(kg) of elder male was significantly(p<0.05) higher than elder female by 8.63kg. 5) The WHR(%) elder female was no significantly higher than elder male by 0.03%. 6) The TBW(l) of elder male was significantly(p<0.05) higher than elder female by 6.321. The factor of significant difference of between elder male and female was %fat, fat mass(kg), free fat mass(kg), total body water(l). 2. The difference of IADL 1) IADL of elder male was no significantly higher than elder female by 1.20. As a result of this study, optimal body composition group was elder male group. Optimal body composition of elder had improved IADL. In addition to, this result of this study, it can suggested the consideration of the Health promotion program for elder.

• Journal of Korea Multimedia Society
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• v.21 no.6
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• pp.723-735
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• 2018

Indicators to quantitatively assess the physical conditions can help optimize the effectiveness of rehabilitation therapy for stroke patients. The body composition variations in the paretic and non-paretic regions of stroke patients with cerebral infarction (7 males, 31 females) were analyzed using multi-frequency bioelectrical impedance. Specifically, resistance (R), lean mass (LM), fat mass (FM), extracellular water (ECW), intracellular water (ICW), R/LM relation, basal metabolic rate (BMR)/LM relation were utilized to evaluate the paretic and non-paretic regions of subjects with cerebral infarction. These values showed significant differences in gender and paretic/non-paretic regions. R and FM were high but LM and ICW were lower in female and paralysis. ECW was lower in females than males, but there was no considerable difference between paralysis and non-paralysis in both males and females. In addition, there was an inverse distribution between R and LM in paretic and non-paretic regions, with males on the upper left and females on the lower right. Furthermore, the relationship between BMR and LM showed excellent linearity (slope: 22.17 kcal/day/kg) irrespective of gender, paralysis, and non-paralysis. An easy, non-invasive and quantitative assessment using bioelectrical impedance would provide an useful tool for evaluating patients with cerebral infarction receiving rehabilitation therapy.

• 한국사회복지학회:학술대회논문집
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• 2004.10a
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• pp.461-492
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• 2004

This study examined the effects of gender, parental support and treatment type on the treatment outcome of adolescent substance abusers. Outcome variable was the successful graduation (or drop) from an Intensive Adolescent Outpatient Program. Adolescents with their parents' support were treated in one of three treatment models (2-weeks Inpatient plus 6 week Intensive Croup-Oriented Outpatient, 8-weeks Intensive Croup-Oriented Outpatient, and 8-weeks Individual-Family Therapy) within a private hospital-affiliated treatment center by managed care practice allowing their own choice (non-random natural assignments). Several hypotheses were tested for main effects by the Log-Linear Analyses for a multi-dimensional contingency table with 440 adolescents (284 boys and 156 girls treated during 1992-l997) from middle-class families with private health insurances. The following results were found. Odds of graduating versus dropping out of the treatment program among : (1) girls were 1.7 times higher than those among boys; (2) adolescents with two-parent were 2.2 times higher than those among adolescents with one-parent ; (3) adolescents with Inpatient plus Outpatient was 1.7 times higher than that of those with Outpatient; (4) adolescents with Individual-Family Therapy was 2.3 times higher than that of those with Outpatient Model. There was no statistically significant outcome difference between the Individual-Family Therapy and the Inpatient plus Outpatient. Implications from the results were discussed. Suggestions were made to improve the treatment components in the areas of gender sensitivity, securing more parental support, alternatives for separation from peer group and integrating new peer groups, and flexibility for the unique needs of individual family. Also, some research questions for future studies were suggested.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.4
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• pp.299-310
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• 2020

Alzheimer's disease (AD) is a multi-faceted neurodegenerative disease. Thus, current therapeutic strategies require multitarget-drug combinations to treat or prevent the disease. At the present time, single drugs have proven to be inadequate in terms of addressing the multifactorial pathology of AD, and multitarget-directed drug design has not been successful. Based on these points of views, it is judged that combinatorial drug therapies that target several pathogenic factors may offer more attractive therapeutic options. Thus, we explored that the combination therapy with lower doses of cilostazol and aripiprazole with add-on donepezil (CAD) might have potential in the pathogenesis of AD. In the present study, we found the superior efficacies of donepezil add-on with combinatorial mixture of cilostazol plus aripiprazole in modulation of expression of AD-relevant genes: Aβ accumulation, GSK-3β, P300, acetylated tau, phosphorylated-tau levels, and activation of α-secretase/ADAM 10 through SIRT1 activation in the N2a Swe cells expressing human APP Swedish mutation (N2a Swe cells). We also assessed that CAD synergistically raised acetylcholine release and choline acetyltransferase (CHAT) expression that were declined by increased β-amyloid level in the activated N2a Swe cells. Consequently, CAD treatment synergistically increased neurite elongation and improved cell viability through activations of PI3K, BDNF, β-catenin and α7-nicotinic cholinergic receptors in neuronal cells in the presence of Aβ_1-42. This work endorses the possibility for efficient treatment of AD by supporting the synergistic therapeutic potential of donepezil add-on therapy in combination with lower doses of cilostazol and aripiprazole.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.2
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• pp.11-20
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• 2020

Purpose : The purpose of this study was to research the effects of dual-hemisphere transcranial direct current stimulation (dual tDCS) and modified constraint-induced movement therapy (mCIMT) to improve upper extremity motor function after stroke. Methods : The study period was from August 2019 to November 2019, and included 24 patients who met the selection criteria. Participants were divided into 2 groups: dual tDCS and mCIMT, and sham dual tDCS and mCIMT group. Dual tDCS and mCIMT group performed mCIMT immediately after applying dual tDCS for 20 minutes, and sham dual tDCS and mCIMT group performed mCIMT immediately after applying sham tDCS for 20 minutes without turning on the power source. Total interventions were conducted 5 times per week for 4 weeks, and mCIMT was conducted for 30 minutes per session for both experimental and control groups. Fugl-Meyer assessment (FMA) and Motor Activity Log scale (MAL) were analyzed before and after 4 weeks of intervention. Results : Both experimental and control groups showed significant changes in FMA, Amount of Use (AOU), and Quality of Movement (QOM) of MAL. When the differences between groups was compared using ANCOVA, the experimental group showed a greater improvement in FMA and AOU of MAL than the control group. Conclusion : In order to enhance the effect of improving upper limb function of stroke patients, dual tDCS could be applied to provide more effective treatment in the clinical setting. Further studies will be needed in larger groups of stroke patients, including long-term follow-up, and multi-group comparisons through the establishment of anodal tDCS and mCIMT, cathodal tDCS, and mCIMT groups to clarify the effects of dual tDCS. In addition, research is needed to establish a protocol for tDCS, and this evidence-based intervention protocol is expected to be used in the clinical setting as an interventional method for various purposes.

• Journal of Lipid and Atherosclerosis
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• v.3 no.2
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• pp.97-104
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• 2014

Objective: The aim of this study is to compare the clinical benefits between high-intensity and low-to moderate-intensity statin therapy in patients with acute myocardial infarction (AMI). Methods: A total of 1,230 patients in the Korea AMI Registry (KAMIR) were enrolled. Patients were divided into two groups according to the dosage of statin for the secondary prevention after AMI. The primary endpoint was composite of major adverse cardiac events (MACEs) including cardiac death, non-fatal MI, repeat revascularization during the 12 months of clinical follow-up. Result: The primary endpoint occurred in 101 patients (11.3%) from the low-to moderate-intensity statin group and 45 patients (13.4%) from the high-intensity statin group. The cumulative incidence of MACEs during 12-month follow-up was not significantly different between the two groups (p=0.323). After multi-variate analysis, MACEs-free survival rate was not significantly different between the two groups. Conclusion: High-intensity statin therapy did not show additional clinical benefit over low-to moderate-intensity statin therapy after AMI.

• Journal of The Korea Institute of Healthcare Architecture
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• v.24 no.4
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• pp.69-87
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• 2018

Purpose: This study has been started with the awareness that light and color are the main visual sensors of the multi-sensory stimulation environment to achieve the therapeutic environment for demented elderly. The purpose of this study therefore is for clarifying the application characteristics of therapeutic light and color for dementia care facilities. Methods: Internal and external literature reviews have been conducted for the investigation into a)disorders and visual system in demented elderly, b)therapeutic effects of light and color, c)heliotherapy, light therapy and color therapy to deduce the therapeutic characteristics of light and color for demented elderly, and finally into d)the application characteristics of it for dementia care facilities. Results: The application characteristics of the therapeutic light and color for dementia care facilities are classified into both qualitative and quantitative characteristics. Qualitative application characteristics of light represented using of daylight, using of lighting approximate to daylight, expansion of iluminance level, equality in iluminance Level, reduction of shadow, and as well as exclusion of blare. Quantitative application characteristics of it represented iluminance level, color temperature and color rendering index prescribed in international lighting standards. Qualitative application characteristics of color represented non-monochromatic color, color contrast, long wavelength of yellow-red colors, exclusion of short wavelength of blue colors and patterns, and as well as different colors for idenfication. Quantitative application characteristics of it represented kontrast(K) prescribed in DIN32975:2009 and light reflectance value(LRV) prescribed in BS8300:2009. Implications: To form dementia care facilities as therapeutic environment both qualitative and quantitative application characteristics of therapeutic light and color in dementia care facilities are needed.