• Imaging Science in Dentistry
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• 제52권3호
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• pp.267-273
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• 2022

Purpose: The aim of this study was to assess the influence of kilovoltage- peak (kVp) and the metal artifact reduction (MAR) tool on the detection of buccal and lingual peri-implant dehiscence in the presence of titanium-zirconia (Ti-Zr) and zirconia (Zr) implants in cone-beam computed tomography (CBCT) images. Materials and Methods: Twenty implant sites were created in the posterior region of human mandibles, including control sites (without dehiscence) and experimental sites (with dehiscence). Individually, a Ti-Zr or Zr implant was placed in each implant site. CBCT scans were performed using a Picasso Trio device, with variation in the kVp setting (70 or 90 kVp) and whether the MAR tool was used. Three oral radiologists scored the detection of dehiscence using a 5-point scale. The area under the receiver operating characteristic (ROC) curve, sensitivity, and specificity were calculated and compared by multi-way analysis of variance (α=0.05). Results: The kVp, cortical plate involved (buccal or lingual cortices), and MAR did not influence any diagnostic values (P>0.05). The material of the implant did not influence the ROC curve values(P>0.05). In contrast, the sensitivity and specificity were statistically significantly influenced by the implant material (P<0.05) with Zr implants showing higher sensitivity values and lower specificity values than Ti-Zr implants. Conclusion: The detection of peri-implant dehiscence was not influenced by kVp, use of the MAR tool, or the cortical plate. Greater sensitivity and lower specificity were shown for the detection of peri-implant dehiscence in the presence of a Zr implant.

• 한국문헌정보학회지
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• 제57권1호
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• pp.93-114
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• 2023

정보추출은 문헌 내에 존재하는 개체명을 인식함과 동시에 이들 간의 의미적 관계까지도 식별하여 최종적으로 문헌 내에 포함된 의미적 트리플을 자동으로 추출하여 활용할 수 있으므로 문헌에 대한 심층적인 분석과 이해에 많은 도움을 줄 수 있다. 그러나 지금까지 대부분의 정보추출에 대한 연구는 개체명 인식과 관계추출이 개별 연구로 각각 분리되어 진행되었으며, 그 결과 입력 문헌에 대한 정보추출의 최종 출력인 의미적 트리플 추출 성능에 대한 객관적이고 정확한 평가가 제대로 이루어지지 않았다. 이에 본 논문에서는 진료 기록 문헌에 나타나는 개체명과 그들 간의 관계를 트리플 형태로 직접 추출할 수 있는 종단형 정보추출의 2가지 모델인 파이프라인 및 결합형 모델을 구축하는 구체적인 방법론을 제시하고 성능 비교 실험을 진행하였다. 우선 파이프라인 모델은 양방향 GRU-CRFs를 활용한 개체명 인식 모듈과 다중 인코딩 기반 관계추출 모듈로 구현되었고, 결합형 모델을 위해서는 다중 헤드 레이블링 기반의 양방향 GRU-CRFs이 적용되었다. 두 가지 시스템을 바탕으로 진료기록 문헌 내의 개체명과 관계를 모두 태깅하여 구축된 i2b2/VA 2010 데이터셋을 활용한 비교 실험에서 파이프라인 모델의 성능이 5.5%(F-measure) 더 높게 나타났다. 추가적으로, 대규모 신경망 언어모델과 수작업으로 구축된 자질 정보를 활용한 최고 수준의 기존 시스템과의 비교 실험을 통해, 본 논문에서 구현한 종단형 모델의 객관적인 성능 수준을 파악할 수 있었다.

• 한국콘텐츠학회논문지
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• 제22권8호
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• pp.416-434
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• 2022

본 연구는 온라인, 오프라인 도구를 사용하는 학습자들을 대상으로 스마트러닝 학습앱의 사용자경험이 지속 사용 의도에 미치는 구조적인 관계를 기술수용모델을 통하여 이해하고, 학습형태 특성을 분류하였다. 또한, 스마트러닝 앱의 사용 경험을 기반으로 학습 도구와 콘텐츠 구성에 대한 사용자 경험 디자인 설계향상 방안을 모색하였다. 이를 위하여 개발된 스마트러닝 학습앱을 중고등학생 대상 학습자 84명을 대상으로 2개월간 사용 후 사용인식을 조사하였으며, PLS구조방정식 기법을 사용하여 자료를 분석하였다. 본 연구의 주요결과는 다음과 같다. 첫째, 시스템 및 콘텐츠 사용자 경험은 지각된 사용성과 지각된 사용 용이성에 유의미한 영향이 있었으며, 태도를 매개로 지속사용 의도에 미치는 영향은 유의미하였다. 둘째, 다중그룹 비교분석과 성별 그룹에서는 시스템 사용자경험이 지각된 유용성에 미치는 영향에서 유의미한 차이가 발생하였다. 선호학습 그룹에서는 유의미한 경로차이를 나타낸 것은 지각된 사용용이성과 지각된 유용성에서 태도 및 지속사용의도로의 경로였다. 셋째, 실제 가장 많이 사용하는 학습유형을 다차원척도법으로 분류한 결과 저차원으로 분리된 유형은 offline sync type, Online sync type, Ubiquitous learning type, Self-direct learning type으로 4가지 유형으로 나타났다.

• Korean Journal of Radiology
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• 제24권10호
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• pp.1006-1016
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• 2023

Objective: Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated the potential of photon-counting detector computed tomography (PCD-CT) in terms of image quality, diagnostic confidence, and radiation dose compared with energy-integrating detector CT (EID-CT). Materials and Methods: In this prospective study, patients with known multiple myeloma underwent clinically indicated whole-body PCD-CT. The image quality of PCD-CT was assessed qualitatively by three independent radiologists for overall image quality, edge sharpness, image noise, lesion conspicuity, and diagnostic confidence using a 5-point Likert scale (5 = excellent), and quantitatively for signal homogeneity using the coefficient of variation (CV) of Hounsfield Units (HU) values and modulation transfer function (MTF) via the full width at half maximum (FWHM) in the frequency space. The results were compared with those of the current clinical standard EID-CT protocols as controls. Additionally, the radiation dose (CTDIvol) was determined. Results: We enrolled 35 patients with multiple myeloma (mean age 69.8 ± 9.1 years; 18 [51%] males). Qualitative image analysis revealed superior scores (median [interquartile range]) for PCD-CT regarding overall image quality (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), edge sharpness (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), image noise (4.0 [4.0-4.0] vs. 3.0 [3.0-4.0]), lesion conspicuity (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), and diagnostic confidence (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]) compared with EID-CT (P ≤ 0.004). In quantitative image analyses, PCD-CT compared with EID-CT revealed a substantially lower FWHM (2.89 vs. 25.68 cy/pixel) and a significantly more homogeneous signal (mean CV ± standard deviation [SD], 0.99 ± 0.65 vs. 1.66 ± 0.5; P < 0.001) at a significantly lower radiation dose (mean CTDIvol ± SD, 3.33 ± 0.82 vs. 7.19 ± 3.57 mGy; P < 0.001). Conclusion: Whole-body PCD-CT provides significantly higher subjective and objective image quality at significantly reduced radiation doses than the current clinical standard EID-CT protocols, along with readily available multi-spectral data, facilitating the potential for further advanced post-processing.

• Journal of Plant Biotechnology
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• 제43권3호
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• pp.347-358
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• 2016

브라시노스테로이드는 식물의 생장과 발육 과정에 있어서 중요한 역할을 담당 할 뿐 아니라 생물학적/ 비 생물학적 스트레스에 대한 복합 저항성을 보인다고 알려져 있다. 따라서 본 연구에서는 브라시노스테로이드와 광범위스트레스 내성을 연결하는 중요한 생물학적 네트워크를 이해하기 위해, Agilent Arabidopsis $4{\times}44K$ oligo chip을 이용하여 브라시노스테로이드 신호가 강화된 bes1-D 계통의 전 전사체 비교분석을 수행하였다. 그 결과 bes1-D 계통에서 DEGs (Differentially Expressed Genes)를 1,091 (562 up-regulated, 529 down-regulated) 개 선발하였다. 또한 선발된 유전자들의 GO 와 단백질 상호작용 네트워크 분석을 통해 대사, 발달, 스트레스, 면역, 방어 반응에 관련된 주요 브라시노스테로이드 신호전달과 연결된 스트레스 관련 유전자군을 분리하였다. 선발된 유전자중 NB-ARC와 FLS2는 bes1-D 계통이 야생형 En-2 계통에 비해 약 6배 정도의 발현량이 증가되었으며, TIR1, TSA1, OCP3 유전자등은 bes1-D 계통이 야생형 En-2 계통에 비해 발현이 감소되었다. 또한 브라시노스테로이드 활성형 계통이 야생형 식물체 계통에 비해 가뭄 스트레스 및 병원균에 대해 저항력이 향상되었다. 따라서 microarray 분석을 통한 유전자 간 발현 네트워크와 유전체 정보를 결합하여 대단위 주요 기능 유전자들을 동정할 수 있는 방법을 고안하여 실험에 사용하였다. 이를 통해 기능 획득 돌연변이 bes1-D가 식물들이 다양한 스트레스 환경에 적응할 수 있는 반응을 조절한다는 사실을 보여주고 있다.

• 지역연구
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• 제35권3호
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• pp.45-58
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• 2019

정부는 최근 서울 근교에 5개의 대규모 공공택지지구, 소위 3기 신도시를 추진하고 있다. 이와 관련하여 본 연구는 신도시를 계획함에 있어 주요하게 고려해야 할 사항들이 무엇인지 설문조사자료를 활용하여 수요자인 주민들의 관점에서 분석하고자 하였다. 이를 위해 기존의 1기 및 2기 신도시와 건설예정인 3기 신도시를 대상으로 환경적 쾌적성, 일자리 등 자족성, 교통접근성과 편리성 등 8개 지표를 종속변수로 하고, 성별, 연령, 가구원수, 가구소득, 직업, 거주지역 등 주민의 특성을 설명변수로 하여 빈도분석 및 분산분석을 실시하였다. 분석결과, 응답자들은 1기 신도시를 2기 신도시에 비해 더 긍정적으로 평가하였다. 일자리 등 자족성 항목에 대하여는 1기와 2기 신도시 모두 낮은 수준으로 나타났다. 또한 1기 신도시는 8개 지표에 대하여 성별, 가구원수, 가구소득에 따른 응답의 유의적 차이가 없었으며, 2기 신도시는 가구원수, 가구소득, 직업, 거주지역에 따른 유의적 차이가 나타나지 않았다. 다만 3기 신도시의 경우 연령, 가구원수, 가구소득 및 직업에 따른 각 지표의 중요성에 대한 평가가 유의적 차이를 나타내었다. 3기 신도시에 대한 다중비교분석 결과를 보면, 환경적 쾌적성에 대하여 청년층, 1인 또는 5인 이상 가구, 관리/전문/사무직이, 교통의 접근성과 편리성의 경우 청년층, 소득이 많은 계층, 관리/전문/사무직에서 중요도를 높게 평가한 것으로 나타났다. 향후 3기 신도시 계획 시에 각 계획지표들에 대한 다양한 개인적 특성과 수요를 고려해야 할 필요가 있음을 시사한다.

• Asia pacific journal of information systems
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• 제20권3호
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• pp.191-204
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• 2010

Recently, the CO2 emission and energy consumption have become critical global issues to decide the future of nations. Especially, the spread of IT products and the increased use of internet and web applications result in the energy consumption and CO2 emission of IT industry though information technologies drive global economic growth. EU, the United States, Japan and other developed countries are using IT related environmental regulations such as WEEE(Waste Electrical and Electronic Equipment), RoHS(Restriction of the use of Certain Hazardous Substance), REACH(Registration, Evaluation, Authorization and Restriction of CHemicals) and EuP(Energy using Product), and have established systematic green business/IT strategies to enhance the competitiveness of IT industry. For example, the Japan government proposed the "Green IT initiative" for being compatible with economic growth and environmental protection. Not only energy saving technologies but energy saving systems have been developed for accomplishing sustainable development. Korea's CO2 emission and energy consumption continuously have grown at comparatively high rates. They are related to its industrial structure depending on high energy-consuming industries such as iron and steel Industry, automotive industry, shipbuilding industry, semiconductor industry, and so on. In particular, export proportion of IT manufacturing is quite high in Korea. For example, the global market share of the semiconductor such as DRAM was about 80% in 2008. Accordingly, Korea needs to establish a systematic strategy to respond to the global environmental regulations and to maintain competitiveness in the IT industry. However, green competitiveness of Korea ranked 11th among 15 major countries and R&D budget for green technology is not large enough to develop energy-saving technologies for infrastructure and value chain of low-carbon society though that grows at high rates. Moreover, there are no concrete action plans in Korea. This research aims to deduce the priorities of the Korean green business/IT strategies to use multi attribute weighted average method. We selected a panel of 19 experts who work at the green business related firms such as HP, IBM, Fujitsu and so on, and selected six assessment indices such as the urgency of the technology development, the technology gap between Korea and the developed countries, the effect of import substitution, the spillover effect of technology, the market growth, and the export potential of the package or stand-alone products by existing literature review. We submitted questionnaires at approximately weekly intervals to them for priorities of the green business/IT strategies. The strategies broadly classify as follows. The first strategy which consists of the green business/IT policy and standardization, process and performance management and IT industry and legislative alignment relates to government's role in the green economy. The second strategy relates to IT to support environment sustainability such as the travel and ways of working management, printer output and recycling, intelligent building, printer rationalization and collaboration and connectivity. The last strategy relates to green IT systems, services and usage such as the data center consolidation and energy management, hardware recycle decommission, server and storage virtualization, device power management, and service supplier management. All the questionnaires were assessed via a five-point Likert scale ranging from "very little" to "very large." Our findings show that the IT to support environment sustainability is prior to the other strategies. In detail, the green business /IT policy and standardization is the most important in the government's role. The strategies of intelligent building and the travel and ways of working management are prior to the others for supporting environment sustainability. Finally, the strategies for the data center consolidation and energy management and server and storage virtualization have the huge influence for green IT systems, services and usage This research results the following implications. The amount of energy consumption and CO2 emissions of IT equipment including electrical business equipment will need to be clearly indicated in order to manage the effect of green business/IT strategy. And it is necessary to develop tools that measure the performance of green business/IT by each step. Additionally, intelligent building could grow up in energy-saving, growth of low carbon and related industries together. It is necessary to expand the affect of virtualization though adjusting and controlling the relationship between the management teams.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2003년도 제20회 춘계학술대회 논문집
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• pp.91-93
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• 2003

A comprehensive numerical study is carried out to investigate for the understanding of the flow evolution and flame development in a supersonic combustor with normal injection of ncumally injecting hydrogen in airsupersonic flows. The formulation treats the complete conservation equations of mass, momentum, energy, and species concentration for a multi-component chemically reacting system. For the numerical simulation of supersonic combustion, multi-species Navier-Stokes equations and detailed chemistry of H2-Air is considered. It also accommodates a finite-rate chemical kinetics mechanism of hydrogen-air combustion GRI-Mech. 2.11[1], which consists of nine species and twenty-five reaction steps. Turbulence closure is achieved by means of a k-two-equation model (2). The governing equations are spatially discretized using a finite-volume approach, and temporally integrated by means of a second-order accurate implicit scheme (3-5).The supersonic combustor consists of a flat channel of 10 cm height and a fuel-injection slit of 0.1 cm width located at 10 cm downstream of the inlet. A cavity of 5 cm height and 20 cm width is installed at 15 cm downstream of the injection slit. A total of 936160 grids are used for the main-combustor flow passage, and 159161 grids for the cavity. The grids are clustered in the flow direction near the fuel injector and cavity, as well as in the vertical direction near the bottom wall. The no-slip and adiabatic conditions are assumed throughout the entire wall boundary. As a specific example, the inflow Mach number is assumed to be 3, and the temperature and pressure are 600 K and 0.1 MPa, respectively. Gaseous hydrogen at a temperature of 151.5 K is injected normal to the wall from a choked injector.A series of calculations were carried out by varying the fuel injection pressure from 0.5 to 1.5MPa. This amounts to changing the fuel mass flow rate or the overall equivalence ratio for different operating regimes. Figure 1 shows the instantaneous temperature fields in the supersonic combustor at four different conditions. The dark blue region represents the hot burned gases. At the fuel injection pressure of 0.5 MPa, the flame is stably anchored, but the flow field exhibits a high-amplitude oscillation. At the fuel injection pressure of 1.0 MPa, the Mach reflection occurs ahead of the injector. The interaction between the incoming air and the injection flow becomes much more complex, and the fuel/air mixing is strongly enhanced. The Mach reflection oscillates and results in a strong fluctuation in the combustor wall pressure. At the fuel injection pressure of 1.5MPa, the flow inside the combustor becomes nearly choked and the Mach reflection is displaced forward. The leading shock wave moves slowly toward the inlet, and eventually causes the combustor-upstart due to the thermal choking. The cavity appears to play a secondary role in driving the flow unsteadiness, in spite of its influence on the fuel/air mixing and flame evolution. Further investigation is necessary on this issue. The present study features detailed resolution of the flow and flame dynamics in the combustor, which was not typically available in most of the previous works. In particular, the oscillatory flow characteristics are captured at a scale sufficient to identify the underlying physical mechanisms. Much of the flow unsteadiness is not related to the cavity, but rather to the intrinsic unsteadiness in the flowfield, as also shown experimentally by Ben-Yakar et al. [6], The interactions between the unsteady flow and flame evolution may cause a large excursion of flow oscillation. The work appears to be the first of its kind in the numerical study of combustion oscillations in a supersonic combustor, although a similar phenomenon was previously reported experimentally. A more comprehensive discussion will be given in the final paper presented at the colloquium.

• 한국유통학회지:유통연구
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• 제17권2호
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• pp.63-92
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• 2012

본 연구는 소비자가 지각하는 유통업체의 위치기반 모바일 쇼핑정보 서비스에 대한 정보의 상황관련성과 정보자극에 대한 PAD 감정변수들(환기, 지배력, 즐거움) 간의 상호 인과관계와 이용의도에 대한 이들의 효과를 실증 연구 하였다. 미국 내 모바일 이용자를 대상으로 무작위 표본추출법에 근거하여 추출되었고, 총 335명의 사용가능한 응답이 수거되었다. 분석결과, 환기와 상황관련성은 즐거움에 정(+)의 영향을 주었으나 지배력은 즐거움에 유의한 영향력을 나타내지 않았다. 즐거움은 이용의도에 정(+)의 영향을 주었다. 본 연구를 통해 위치기반 모바일 서비스에 대한 소비자의 인지적 반응과 감정적 반응을 통합적으로 살펴보았으며, PAD 감정차원간의 체계적인 관계를 규명하였다. 연구결과를 바탕으로 모바일 쇼핑서비스 개발자, 유통업체, 그리고 마케팅 실무자를 위한 시사점을 논의하였으며, 연구의 한계점과 더불어 향후 연구 방향을 제시하였다.

• 대한후두음성언어의학회지
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• 제33권1호
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• pp.20-25
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• 2022

Background and Objectives Globus pharyngeus is one of the most common symptoms of patients visiting otorhinolaryngology out-patient clinic, and usually long-lasting, difficult to treat, and frequently recurrent. Mucomyst^®, N-acetyl cysteine is an inhalation agent mainly used for mucolysis and reducing inflammation in airway via antioxidative effect. The purpose of this study was to evaluate the efficacy of inhaled Mucomyst^® treatment in patients with globus pharyngeus refractory to proton pump inhibitor (PPI). Materials and Method We prospectively evaluated the efficacy of Mucomyst^® in relieving symptoms of globus pharyngeus refractory to PPI in nine medical centers. Three hundred and three patients enrolled and finally 229 patients finished the inhaled Mucomyst^® therapy for 8 weeks. We analyzed the change of Reflux Symptom Index (RSI), Reflux Finding Score (RFS), Visual Analogue Scale (VAS) for globus, and Globus Pharyngeus Symptom Scale (GPS) after use of Mucomyst^® for 4 and 8 weeks. Results The GPS, RSI, RFS, and VAS score significantly decreased serially in patients who finished 8 week-inhalation treatment. The GPS improvement gap was significantly correlated with initial GPS (p<0.001) in multiple regression analysis. Conclusion Inhaled Mucomyst^® therapy was effective for the reduction of both subjective and objective findings in refractory globus patients. This study might suggest new treatment option for patients with globus. However, further thorough studies would be needed to assess the real effect of inhaled Mucomyst^® treatment as a standard treatment for globus.