• 한국산학기술학회논문지
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• 제22권2호
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• pp.794-801
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• 2021

이 연구는 electric resistance element spot welding 프로세스를 도입하여 알루미늄 합금-강철의 이종 접합부의 기계적 강도 및 내식성을 향상시키기 위해 수행되었다. SPFC980Y 강철과 Al5052-H32가 각각 모재로써 적용되었고, S20C 강철은 리벳 element로써 음각과 양각의 형상으로 구분되며, Al5052-H32에 전기 저항 스폿 용접을 위해 리벳팅 되어 6.5 kA의 전류와 250 kgf/㎠의 가압력으로 접합되었다. 그 결과, 음각된 S20C element는 스폿 용접 공정 후 불안정한 너깃이 형성되는 반면, 양각된 S20C의 경우, 구조적으로 건전한 접합부로 건전한 내식성 및 탁월한 기계적 특성이 얻어졌다. FEM 시뮬레이션의 도입으로, 음각과 양각의 계면의 접합 특성이 수치적으로 밝혀졌으며, 시뮬레이션 결과는 미세조직 발달 양상을 수치적으로 뒷받침하였다. 이 연구는 element 스폿 용접된 H32-A5052 이종 접합부의 기계적 강도 및 부식 신뢰성에 대해 체계적으로 분석되었으며, 이 공정은 금속재료뿐만 아니라, 경량 비전도성 비철/비금속계 재료에도 적용 될 수 있기 때문에, 차세대 차체 경량화의 양산 기술로 확장 될 수 있다.

• 센서학회지
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• 제21권3호
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• pp.172-179
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• 2012

This paper presents the design and analysis of a vibration-driven electromagnetic energy harvester that uses a multi-pole magnet. The physical backgrounds of the vibration electromagnetic energy harvester are reported, and an ANSYS finite element analysis simulation has been used to determine the different alignments of the magnetic pole array with their flux lines and density. The basic working principles for a single and multi-pole magnet are illustrated and the proposed harvester has been presented in a schematic diagram. Mechanical parameters such as input frequency, maximum displacement, number of coil turns, and load resistance have been analyzed to obtain an optimized output power for the harvester through theoretical study. The paper reports a maximum of 1.005 mW of power with a load resistance of $1.9k{\Omega}$ for 5 magnets with 450 coil turns.

• Bulletin of the Korean Chemical Society
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• 제34권4호
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• pp.1272-1274
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• 2013

• 전력전자학회:학술대회논문집
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• 전력전자학회 2007년도 하계학술대회 논문집
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• pp.175-177
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• 2007

An analysis on a passive current sharing characteristics of a multi-phase synchronous buck converter is presented. The passive current sharing method is simple but its characteristics depend on the converter equivalent resistance and PWM uniformity. In this paper, the load sharing and power consumption of the passive current sharing system for the converter equivalent resistance and duty ratio inequalities are investigated through the simulation and experiment.

• 한국육종학회지
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• 제43권5호
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• pp.413-421
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• 2011

본 연구에서는 관행의 교배육종과 DNA 마커를 이용한 MAS의 접목을 통하여 벼멸구 저항성과 관련된 단점을 보완하고, 효율적으로 도열병, 줄무늬잎마름병, 흰잎마름병, 벼멸구, 끝동매미충 저항성이 집적된 복합내병충성 우량계통을 육성하고자 수행하였다. 교배모본으로는 완전미율이 높고, 끝동매미충에 저항성인 '남평'과 단간이면서 흰잎마름병에 저항성인 '주남'을 반복친으로 사용하였고, 벼멸구저항성 유전자 Bph1을 가지고 있지만 간장이 크고 재배안전성이 미흡한 '밀양220호'를 공여친으로 사용하였다. 벼멸구 저항성 연관마커 RM28493을 이용하여 $BC_1F_1$ 및 $BC_2F_1$ 세대에서 MAS로 저항성 개체 선발과 여교잡을 수행하였으며, 복교잡 $F_1$ 세대에서 MAS를 통한 벼멸구 저항성이 고정된 계통을 선발하였다. 고세대 계통에서 생물검정을 통하여 흰잎마름병, 끝동매미충에 저항성인 계통을 선발하였다. MAS와 생물검정을 통해 도열병, 흰잎마름병, 줄무늬잎마름병, 벼멸구 및 끝동매미충에 저항성인 85개의 복합내병충성계통을 선발하였다. 복합내병충성 계통의 간장, 완전미율 및 수량은 각각 71~88 cm, 51~93%, 449~629 kg/10a 사이에 분포하였다. 복합내충성계통중 간장, 완전미율 및 수량이 남평벼와 비슷한 계통을 선발하여 '밀양265호'로 명명하였다. 최종적으로 본연구에서는 기존의 교배육종과 분자육종의 접목을 통하여 복합내병충성 우량계통을 육성하였으며, 이는 금후 유용교배모본으로 활용될 것으로 기대된다.

• 전자공학회논문지
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• 제53권8호
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• pp.39-48
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• 2016

본 논문에서는 소스와 드레인의 구조가 육각형인 FinFET에서 구조 변수 및 핀/핑거 개수 증가에 따른 열 저항 모델을 제안한다. 소자의 크기가 감소하여 발열 효과 및 열 특성의 영향이 커졌으며, 이를 분석하기 위해 소자의 열 저항은 중요한 요소이다. 열 저항 모델은 소자에서 열이 생성되는 열원과 열이 빠져나가는 contact를 설정했으며, 도메인은 열원과 4 부분의 소스, 드레인, 게이트, 서브스트레이트 contact를 통해 나누어진다. 또 각각의 contact 열 저항 모델은 TCAD의 시뮬레이션 결과의 온도 및 열 흐름을 분석하여 해석이 용이한 형태로 세분화하였다. 도메인들은 그 구조에 따라 구조 변수를 통한 적분 및 등각 매핑 방식을 기반으로 모델링하였다. 먼저 싱글 핀으로 열 저항을 분석하여 모델링하였으며, 멀티 핀/핑거의 열 저항 모델의 정확도를 높이기 위해 채널증가에 따른 파라미터의 변화를 적용하였다. 제안한 열 저항 모델은 3D Technology CAD 시뮬레이션을 해석하여 얻은 열 저항 결과와 비교하였으며, 싱글 핀 및 멀티 핀의 전체 열 저항 모델은 3 % 이하의 오차를 얻었다. 제안한 열 저항은 핀/핑거 개수의 증가에 따른 열 저항을 예측할 수 있으며, 발열효과 및 열 특성 분석을 계산하여 회로 특성을 개선할 수 있다.

• 한국초전도ㆍ저온공학회논문지
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• 제6권2호
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• pp.20-24
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• 2004

Bi-2223 wire, the first-generation high temperature superconducting (HTS) wire, was successfully commercialized and various electrical machinery and equipment are actively being developed in many countries. Because its critical current is too small to realize the lossless conducting part of electric power system with a HTS wire, multi-HTS paths are used to enlarge the critical current of HTS system. Though the resistance generated in HTS wire by transport current is very small, the difference of it in multi-path is the additional reason which causes the non-uniform current sharing in multi-HTS path except the well known reason, the difference of inductance between each path. In this paper, experimental research on current sharing of multi-strand and multi-stacked HTS wire was implemented. The whole critical current of multi-HTS paths is not equal to sum of critical current of each path because of non-uniform current sharing occurred in this paths. It was verified experimentally that Bi-2223 wires have different resistance generated by same transport current even if they was manufactured in same progress of work. Current sharing phenomenon was affected by difference of resistance and self and mutual inductance.

• 한국재난정보학회 논문집
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• 제3권2호
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• pp.147-169
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• 2007

This study investigates the reinforcing effects of the Multi-bar Spring nails with respect to the conventional Soil-nails in artificial slopes. Based on wide experience related to design and construction, soil nails have been widely applied to reinforce slope in the world. Multi-bar spring nails are one of the improved soil nailing methods. These method maximizes bending, shearing, pull-out resistance for those multi-nails, not unit nail, that are inserted in the borehole using special spacer at regular intervals. In addition, because cutting plane is confined effect resulting from a pressured plate at the end of the nails with compression spring equipment, slope stability is secured using MS-nailing method. Analyzing bending, pull-out, shearing condition of MS-nail, it was examined throughly elastic region, load transfer capacity, reinforcing effect on cutting plate of MS-nails. In addition, Pilot and laboratory tests, numerical analysis were carried out to verify the superiority of MS-nailing method. In case, MS nailing method is applied to reinforce artificial slope, it was analyzed that bending, pull-out, shearing resistance was increased more than existing nailing method was applied. In this study, it was shown that surface failure was more or less prevented using MS-nailing method, confining effect on cutting plane using spring stuck to flexible equipment.

• Archives of Pharmacal Research
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• 제29권12호
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• pp.1067-1073
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• 2006

Cisplatin, a platinum coordinated complex, is a widely used antineoplastic agent for the treatment of metastatic tumors of the testis, metastatic ovarian tumors, lung cancer, advanced bladder cancer and many other solid tumors. The cytotoxic action of the drug is often thought to be associated with its ability to bind DNA to form cisplatin-DNA adducts. The development of resistance to cisplatin during treatment is common and constitutes a major obstacle to the cure of sensitive tumors. Although to understand the clinically relevant mechanisms of resistance, many studies have been aimed at clarifying the biochemical/molecular alterations of cisplatin-resistance cells, these studies did not conclusively identify the basis of cellular resistance to cisplatin. In this review, cisplatin resistance was discussed in terms of the relevant transporters, such as copper transporters (CTRs), organic cation transporters (OCTs) and multi-drug resistance related transporters (MDRs). These transporters seem to be contributed to cisplatin resistance through the reduction of drug accumulation in the cell. Better understanding the mechanism of cisplatin resistance associated with transporters will provide the useful informations for overcoming the cisplatin resistance.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2619-2623
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• 2014

Aim: To investigate signaling pathways for reversal of EGF-mediated multi-drug resistance (MDR) in hepatocellular carcinoma (HCC) models. Materials and Methods: HCC MDR cell strain HepG2/adriamycin (ADM) and SMMC7721/ADM models were established using a method of exposure to medium with ADM between low and high concentration with gradually increasing concentration. Drug sensitivity and reversal of multi-drug resistance by EGF were determined and the cell cycle distribution and apoptosis were analyzed by flow cytometry. Phosphorylation of ERK1, ERK2, ERK5 and expression of Bim were detected by Western blotting. Results: The results showed that HepG2/ADM and SMMC7721/ADM cells were resistant not only to ADM, but also to multiple anticancer drugs. When used alone, EGF had no anti-tumor activity in HepG2/ADM and SMMC7721/ADM cells in vitro, while it increased the cytotoxicity of ADM. EGF induced cell apoptosis and G0/G1 phase cell cycle arrest in HepG2/ADM And SMMC7721/ADM cells, while enhancing activity of p-ERKs and up-regulated expression of BimEL. Conclusions: EGF might enhance the chemosensitivity of HepG2/ADM and SMMC7721/ADM cells via up-regulating p-ERKs and BimEL protein.