• Title/Summary/Keyword: Multi-head Deposition System

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Fabrication of 3D PCL/PLGA/TCP Bio-scaffold using Multi-head Deposition System and Design of Experiment (다축 적층 시스템과 실험 계획법을 이용한 3차원 PCL/PLGA/ICP 바이오 인 공지지체 제작)

  • Kim, Jong-Young;Yoon, Jun-Jin;Park, Eui-Kyun;Kim, Shin-Yoon;Cho, Dong-Woo
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.1
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    • pp.146-154
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    • 2009
  • In recent tissue engineering field, it is being reported that the fabrication of 3D scaffolds having high porous and controlled internal/external architectures can give potential contributions in cell adhesion, proliferation and differentiation. To fabricate these scaffolds, various solid free-form fabrication technologies are being applied. The solid free-form fabrication technology has made it possible to fabricate solid free-form 3D microstructures in layer-by-layer manner. In this research, we developed a multi-head deposition system (MHDS) and used design of experiment (DOE) to fabricate 3D scaffold having an optimized internal/external shape, Through the organization of experimental approach using DOE, the fabrication process of scaffold, which is composed of blended poly-caprolactone (PCL), poly-lactic-co-glycolic acid (PLGA) and tricalcium phosphate (TCP), is established to get uniform line width, line height and porosity efficiently Moreover, the feasibility of application to the tissue engineering of MHDS is demonstrated by human bone marrow stromal cells (hBMSCs) proliferation test.

Development of Hybrid-FDM Process Using Automatic Tool Changer for Multi-Material Production and Post-Processing (자동공구교환장치를 이용한 융합 FDM 공정 및 장치개발에 관한 연구)

  • Choi, Sung Min;Jian, Xiao;Park, In Baek;Lee, Seok Hee
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.3
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    • pp.235-242
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    • 2016
  • The purpose of this study is an attempt to improve the functionality of a conventional Fused Deposition Modeling (FDM) process using the Automatic Tool Changer (ATC) to perform multimaterial production and post-processing. Hybrid-FDM means a fusion of an Additive Manufacturing process and grinding process using the ATC system. In order to enhance the potentiality of production capacity for multi-material fabrication and surface roughness improvement, two extrusion tools and one grinding tool system are suggested. A pneumatic chuck is attached on a moving platform in the XY axes plane and an extrusion head and grinding head are placed in a docking station, allowing for a quick changeover with each other. Therefore, the manufacturing lead time can be reduced efficiently for the fabrication of a product.

Design and Fabrication of Nasal-Implant-Shaped Scaffold and Regeneration of Nasal Cartilage Tissue for Rhinoplasty (코 성형을 위한 코 보형물 형태의 인공지지체 설계 및 제작과 코 연골조직의 재생)

  • Jung, Jin-Woo;Jang, Jin-Ah;Shim, Jin-Hyung;Kim, Sung-Won;Cho, Dong-Woo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.11
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    • pp.1111-1117
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    • 2012
  • Implants for rhinoplasty should ideally be biocompatible and possess long-term stability after implantation. Silicone implants are most widely used for rhinoplasty. However, these implants suffer from problems related to high extrusion and infection rates. To minimize these complications, we propose a novel augmentation rhinoplasty technique using tissue engineering. To demonstrate its feasibility, a nasal-implant-shaped scaffold was designed using commercialized CAD software and fabricated using a Multi-head Deposition System, which is a solid freeform fabrication system that dispenses material. In vitro cell proliferation and chondrogenic differentiation tests were carried out using nasal septal chondrocytes.

An Experimental Study on the Stability of Breakwater Head by the Wave Directional Effects (입사파의 방향성효과에 의한 방파제 제두부의 안정성에 관한 실험적 연구)

  • SOHN Byung-Kyu;KIM Hong-Jin;RYU Cheong-Ro
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.34 no.6
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    • pp.713-719
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    • 2001
  • The aim of this study is to check the application criteria of the conventional techniques and clarify the effects of breaker depth, seabed conditions on the stability in relation to the effects of uncertainty of storm duration and directional irregular waves. The typical damage modes were divided by the direct wave force on the armor unit and by the local scouring around the toe of a breakwater head by the model experiments. The destruction modes are defined, and some criteria on the damage modes and scouring/deposition at the toe of a breakwater head in relating the wave-bottom-structural conditions can be checked using the multi-directonal irregular wave generator system. According to the results, it is emphasized that the 3-D effects on the stability should be analyzed in the design of multi-purpose/function coastal structures in consideration of the evaluation of spatial variation of damage modes and hydraulic characteristics as well as the wave distribution along the structures.

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