• 제목/요약/키워드: Multi Factor

검색결과 2,151건 처리시간 0.034초

임상가를 위한 특집 3 - rhBMP-2와 LFA-collagen scaffold를 이용한 BRONJ의 성공적인 치료 전략 (Successful strategy of treatment used to rhBMP-2 and LFA-collagen scaffold for BRONJ)

  • 권경환
    • 대한치과의사협회지
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    • 제52권4호
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    • pp.218-233
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    • 2014
  • Bispbosphonates are a class of pharmaceutic agents, which induce apoptosis of osteoclast as well as impair osteoclastic activity to suppress bone resorption. Thus, bisphophonates are effectively used to treat osteoporosis, multiple myeloma and to prevent bone metastases of malignant cancer. However, recently dental disease have been reported associated with Bisphosphonates. Thus, there are a number of discussions about proper prevention and treatment of bisphosphonate-related osteonecrosis of jaw(BRONJ). Marshall R. Urist in 1965 made the seminal discovery that a specific protein, BMP(bone morphogenetic protein), found in the extracellular matrix of demineralized bone could induce bone formation newly when implanted in extraosseous tissues in a host. BMPs are multi-functional growth factors which are members of the transforming growth factor-beta super family and their ability is that plays a pivotal roll in inducing bone. About 18 BMP family members have been identified and characterized. Among of them, BMP-2 and BMP-7 have significant importance in bone development. In this study, patients of BRONJ were recieved who visited Department of oral and maxillofacial surgery, school of dentistry, Wonkwang university for past 3 years from 2011 to 2013. We focused on the results of the surgical intervention. We suggest that new strategy of treatment used to rhBMP-2 and LFA(Lidocaine-Fibrinogen-Aprotinin)-collagen scaffold for patients of BRONJ. The purpose of this paper is to give a brief overview of BMPs and to critically review the clinical data currently available on rhBMP-2 and LFA collage scaffold.

Optimal Location of FACTS Devices Using Adaptive Particle Swarm Optimization Hybrid with Simulated Annealing

  • Ajami, Ali;Aghajani, Gh.;Pourmahmood, M.
    • Journal of Electrical Engineering and Technology
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    • 제5권2호
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    • pp.179-190
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    • 2010
  • This paper describes a new stochastic heuristic algorithm in engineering problem optimization especially in power system applications. An improved particle swarm optimization (PSO) called adaptive particle swarm optimization (APSO), mixed with simulated annealing (SA), is introduced and referred to as APSO-SA. This algorithm uses a novel PSO algorithm (APSO) to increase the convergence rate and incorporate the ability of SA to avoid being trapped in a local optimum. The APSO-SA algorithm efficiency is verified using some benchmark functions. This paper presents the application of APSO-SA to find the optimal location, type and size of flexible AC transmission system devices. Two types of FACTS devices, the thyristor controlled series capacitor (TCSC) and the static VAR compensator (SVC), are considered. The main objectives of the presented method are increasing the voltage stability index and over load factor, decreasing the cost of investment and total real power losses in the power system. In this regard, two cases are considered: single-type devices (same type of FACTS devices) and multi-type devices (combination of TCSC, SVC). Using the proposed method, the locations, type and sizes of FACTS devices are obtained to reach the optimal objective function. The APSO-SA is used to solve the above non.linear programming optimization problem for better accuracy and fast convergence and its results are compared with results of conventional PSO. The presented method expands the search space, improves performance and accelerates to the speed convergence, in comparison with the conventional PSO algorithm. The optimization results are compared with the standard PSO method. This comparison confirms the efficiency and validity of the proposed method. The proposed approach is examined and tested on IEEE 14 bus systems by MATLAB software. Numerical results demonstrate that the APSO-SA is fast and has a much lower computational cost.

차량 제동성능 개선을 위한 타이어 인자 분석 및 최적설계에 대한 연구 (A Study on Effect Analysis and Design Optimization of Tire and ABS Logic for Vehicle Braking Performance Improvement)

  • 기원용;이광우;허승진;강대오;김기운
    • 한국자동차공학회논문집
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    • 제24권5호
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    • pp.581-587
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    • 2016
  • Braking is a basic and an important safety feature for all vehicles, and the final braking performance of a vehicle is determined by the vehicle's ABS performance and tire performance. However, the combination of excellent ABS and tires will not always ensure good braking performance. This is due to the fact that tire performance has non-linearity and uncertainty in predicting the repeated increase and decrease of wheel slip when activating the ABS, thus increasing the uncertainty of tire performance prediction. Furthermore, existing studies predicted braking performance after using an ABS that used a wheel slip control as a controller, which was different from an actual vehicle's ABS that controlled angular acceleration, therefore causing a decrease in the prediction accuracy of the braking performance. This paper reverse-designed the ABS that controlled angular acceleration based on the information on brake pressure, etc., which were obtained from vehicle tests, and established a braking performance prediction analysis model by combining a multi-body dynamics(MBD) vehicle model and a magic formula(MF) tire model. The established analysis model was verified after comparing it with the results of the braking tests of an actual vehicle. Using this analysis model, this study analyzed the braking effect by vehicle factor, and finally designed a tire that had optimized braking performance. As a result of this study, it was possible to design the MF tire model whose braking performance improved by 9.2 %.

무선 센서 네트워크에서 적응적인 링크 품질 측정 (Adaptive Link Quality Estimation in Wireless Sensor Networks)

  • 이정욱;원광호;정광수
    • 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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    • 제16권5호
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    • pp.556-560
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    • 2010
  • 멀티 홉을 이용하는 무선 센서 네트워크에서는 환경적 요인과 노드의 하드웨어적 제약으로 인해 링크의 품질변화가 불규칙하게 일어난다. 이러한 불규칙성에 대응하여 적절한 경로를 선택하지 못한다면 데이터의 손실이 빈번하게 일어날 수 있다. 기존에는 비컨을 주기적으로 브로드캐스팅하여 링크의 품질을 측정하였지만, 이 기법은 불규칙하게 변화하는 링크의 품질을 효율적으로 측정할 수 없다. 본 논문에서는 네트워크의 상태에 따라 링크의 품질 측정 주기를 적응적으로 측정하는 기법을 제안한다. 링크의 품질이 변화할 때 민첩하게 변화에 대응하여 패킷 손실을 줄이고 변화가 없을 때는 긴 주기로 링크 품질을 측정하여 에너지 소모를 줄이고자 한다. 실험을 통하여 제안된 기법이 기존에 제안된 기법보다 에너지 효율 및 패킷 수신율을 향상시킬 수 있음을 확인하였다.

간척지 설치 온실의 난방부하 특성 분석 (Analysis of Heating Load Characteristics for Greenhouses Constructed in Reclaimed Lands)

  • 남상운;신현호
    • 한국농공학회논문집
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    • 제59권6호
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    • pp.1-8
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    • 2017
  • The purpose of this study was to provide basic data for development of environmental design technology for greenhouses constructed in reclaimed lands. We analyzed the climatic conditions around seven major reclaimed land areas in Korea, which have a plan to install advanced horticultural complexes. The characteristics of heating load through the thermal environment measurement of the greenhouse in Saemangeum were analyzed. The part to be applied to the environmental design of the greenhouses in reclaimed lands were reviewed. The overall heat transfer coefficient of the experimental greenhouse with the aluminum screen and multi-layer thermal curtain averaged $3.79W/m^2^{\circ}C$. It represents a 44 % heat savings rate compared with plastic greenhouses with a single covering, which was significantly lower than that of the common greenhouses with 2-layer thermal curtains. This is because the experimental greenhouse was installed on reclaimed land and wind was stronger than the inland area. Among the total heating load, the transmission heat loss accounted for 96.4~99.9 %, and the infiltration loss and the ground heat exchange were low. Therefore, it is necessary to take countermeasures to minimize the transmission heat loss for greenhouses constructed in reclaimed lands. As the reclaimed land is located on the seaside, the wind is stronger than the inland area, and the fog is frequent. Especially, Saemangeum area has 2.6 times stronger wind speed and 3.4 times longer fog duration than the inland area. In designing the heating systems for greenhouses in reclaimed lands, it is considered that the maximum heating load should be calculated by applying the wind coefficient larger than the inland area. It is reasonable to estimate the operation cost of the heating system by applying the adjustment factor 10 % larger than the average in calculating the seasonal heating load.

디지털변전소 통합 IED 용 Process Bus 네트워크 통신지연 시뮬레이션 연구 (A Study on Simulation Analysis for the Transmission Delay on the Process bus network in IEC 61850 Digital Substation)

  • 김석곤;안용호;장병태;최종기;이남호;한정열;이유진
    • 조명전기설비학회논문지
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    • 제29권8호
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    • pp.18-22
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    • 2015
  • Digitalization of the substation in Korea has been in progress so far with focusing on Station Bus. However, its application to Process Bus has been delayed due to some technical issues. IEDs based on Process Bus use the data values of SV and GOOSE. As the size of communication data on Process Bus is comparatively bigger than that of Station Bus, it is very important for the evaluating the performance of Process Bus to analyze the transferring speed and quality of data from the first equipment, which is located on process level, to station level. According to the results of related studies, it is said that the most important factor for the design and operation of Process Bus network is the communication delay with consideration of the volume of packets. In the paper, the results of performance test for the network with and without application of VLAN on Process Bus system that uses integrated IEDs are presented. Additionally, the paper proposes the optimal method to analyze the communication delays of network systems through evaluating the maximum delay time, link process ratio and the amount of lost packets by using a simulation tool.

주거환경에 대한 거주자 시각만족의 경험적 모형 (Residents' Satisfaction with Visual Appearance of the Housing Environment in Korean Multi-Family Housing)

  • 진양교
    • 한국조경학회지
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    • 제21권4호
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    • pp.15-27
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    • 1994
  • 주거환경에서 거주자의 '시각만족(residents' satisfaction with visual appearance)은 더 큰 추상적 개념인 '주거만족'(residents' housing satisfaction)과의 밀접한 인과적 관련(Francescato et. al., 1979) 때문뿐만 아니라 인간 기본 욕구 중의 하나인 미적 욕구의 충족과 관련되어 있다는 점(Chin, 1991)에서도 중요시 되어야 할 이론적 개념이다. 본 연구에서는 거주자의 시각만족을 종속지표로 보고, 다양한 영향 가설변수들과의 인과 적 관련도를 경로분석(path analysis)을 통해 검증하고 있으며, 어떤 변수 가 어떤 이유(경로)로 또는 얼마만한 크기로 거주자의 시각만족에 영향을 주는 가가 중점적으로 토의된다. 한국의 6개 대단위 주거단지로부터 다단 계표집 방법과 설문면담 방법을 통해 646명의 응답이 수거되었다. 분석의 첫 단계로써, 다수의 설문문항을 본 연구의 가설 변수로 집약하기 위한 요 인분석(factor analysis)이 사용되었고, 요인 분석으로부터 추출된 변수들간 의 인과적 관련도를 검증하기 위해 최종적으로 경로분석이 사용되었다. 본 연구의 결과를 요약해 볼 때, 본 연구의 가설 변수 대부분이 최종 종속변 수인 거주자의 '시각만족'에 유의한 인과 영향을 보이는 것으로 나타났으 며, 구체적으로 '시각적 무질서'(visual disorder), '시각적 단조로움'(visual monotony), '단지 과밀감'(development crowding) 등이 부정적 영향을, '시 각적 매력'(visual attractiveness)과 '인근 자연녹지의 존재'(presence of nearby natural environment)등이 긍정적 영향을 미치는 것으로 파악되었 다. 그 외에도 '옥외공간이용 편리'(outdoor or recreation convenience)와 ' 이웃만족'(satisfaction with neighbors), 그리고 '주거환경 유형'(building type, building arrangement type)등도 유의한 인과적 관련을 보이므로써, 기존 문헌들이 제시하고 있는 것보다 훨씬 다양한 변수들이 다양한 경로를 통해 거주자 시각만족의 영향인자가 될 수 있는 가능성을 제시하고 있다. 가설 변수의 하나인 '길찾기의 난이 정도'(difficulty of way-finding)와 종 속변수간에 유의한 관련도가 나타나지 않은 이유로 길찾기 변수가 '시각만 족'보다는 거주자의 '안전만족'(safety)과 관련된 변수일 가능성도 아울러 지적되었다. 본 연구의 결과로부터, 주거 계획 및 설계분야 그리고 추후 관 련 연구 분야를 위한 여러 제안들이 제시되었다.

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상관차원에 의한 비선형 뇌파 분석과 기질성격척도(TCI) 요인간의 상관분석 (Correlation over Nonlinear Analysis of EEG and TCI Factor)

  • 박진성;박영배;박영재;허영
    • 대한한의진단학회지
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    • 제11권2호
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    • pp.96-115
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    • 2007
  • Background and Purpose: Electroencephalogram(EEG) is a multi-scaled signal consisting of several components of time series with different origins. Recently, because of the absence of an identified metric which quantifies the complex amount of information, there are many limitations in using such a linear method. According to chaos theory, irregular signals of EEG can also result from low dimensional deterministic chaos. Chaotic nonlinear dynamics in the EEG can be studied by calculating the correlation dimension. The aim of this study is to analyze correlation between the correlation dimension of EEG and psychological Test (TCI). Methods: Before and after moxibustion treatment, EEG raw data were measured by moving windows during 15 minutes. The correlation dimension(D2) was calculated from stabilized 40 seconds in 15 minutes data. 8 channels EEG study on the Fp, F, T, P was carried out in 30 subjects. Results: Correlation analysis of TCI test is calculated with deterministic non-linear data and stochastic non-linear data. 1. Novelty seeking in temperament is positive correlated with D2 of EEG on Fp. 2. reward dependence in temperament is positive correlated with D2 of EEG on T3,T4 and negative correlated with D2 of EEG on P3,P4. 3. self directedness in character is positive correlated with D2 of EEG on F4, P3. 4. Harm avoidance is negative correlated with D2 of EEG on Fp2, T3, P3. Conclusion: These results suggest that nonlinear analysis of EEG can quantify dynamic state of brain abolut psychological Test (TCI).

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수상태양광의 시공기술에 관한 실증연구 (The Technique of Installing Floating Photovoltaic Systems)

  • 최영관;이종석
    • 한국산학기술학회논문지
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    • 제14권9호
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    • pp.4447-4454
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    • 2013
  • 2011년 10월 국내 최초로 다목적댐 저수지에 100kW급 수상태양광발전 상용화 실증 플랜트가 합천댐에 설치되었다. 수상태양광발전 설비는 육상에 설치하는 태양광발전 설비와는 달리 수상부유체, 계류장치, 수중케이블 등 설치에 많은 어려움이 있다. 특히 수상이라는 환경적 제약으로 인해 육상 태양광 시공 방법으로 공정 관리를 할 수 없는 많은 변수가 속출한다. 수상태양광발전의 구조체는 수상태양광 모듈 및 기타 전기설비를 수상에 부상시키기 위한 설비로서 바람이나 태풍 등 기상환경에 견뎌야 하고 수질에 악영향을 미치지 말아야하며 시공성, 경제성 등 종합적인 고려가 필요하다. 본 논문에서는 100kW 수상태양광 시공사례를 바탕으로 수상태양광의 구조체, 계류장치, 수중케이블, 전력설비 및 원격감시제어시스템의 시공기술에 대한 기초자료를 제공하였다. 본 연구에서 시공된 100kW 수상태양광은 현재 평균 설비이용률 15%로 운영중에 있다.

자가 음성평가와 체질량지수의 특성 비교 (A Comparison study on the relationship between the Self-reported Voice Problem and Body Mass Index)

  • 이인애;황영진
    • 한국산학기술학회논문지
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    • 제14권3호
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    • pp.1330-1334
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    • 2013
  • 본 연구에서는 자가 음성평가에 따른 체질량지수를 비교하고자 하였다. 제5기(2010년) 1차년도 국민건강영양 조사 이비인후과 검진을 완료한 19세 이상의 성인을 5,811명을 대상으로 하며 자가음성평가와 체질량지수의 연관성을 분석하였다. 또한 체질량지수와 연관성이 깊은 키, 몸무게, 허리둘레 등도 함께 비교하여 자가음성평가와 어떠한 상관을 보이는지 살펴보았다. 비교를 위해 chi-square, t-test, 이변량 로지스틱 회귀분석을 이용하였으며 그 결과, 자가 음성평가에 따른 체질량지수는 유의한 차이를 나타내는 특성을 보이며, 체질량지수가 과체중-2단계 비만인 경우 정상체중보다 음성장애 위험률이 1.77배 높은 결과를 나타내었다. 또한 체질량지수가 음성장애 통제변수로서의 유의함을 확인하였으며, 음성장애 진단 시 키와 몸무게를 통한 체질량지수를 함께 비교하는 것은 필요하다는 것이 확인되었다.