• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.10
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• pp.1595-1600
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• 2013

In the present study,effect of natural mulbelly leaf tea on DMEM MDCK cell line. Mulbelly leaf teas inhibited the proliferation in primery MDCK cells in a dose dependent manner. These results show that mulbelly teas potent inhibits the reactive oxygen species (ROS) and not destruction a component. Therefore, mulbelly teas might improve overall quality of the color and taste. And might be applied newly to development of componant mulbelly teas quality and biochemical change by ROS in living things.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.2
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• pp.40-51
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• 2022

Objective This study identified useful herbal medicines and prescriptions for obesity treatment by analyzing herbal medicines and prescriptions that showed meaningful results in weight loss by changing the gut microbiota. Methods Using PubMed, we selected and studied 23 papers showing meaningful results on weight loss through changes in the gut microbiota using herbal medicines. Result Of the 23 selected papers, 17 were of studies using herbal medicines, and 6 of studies using prescriptions. Pomegranate peel, Flos Lonicera, Rehmannia glutinosa, Rhein, Coix seed, Platycodon grandiflorus, mulberry leaves, Poria cocos, asperuloside, Bupleuri radix, Astragalus polysaccharides, Ephedra sinica, Ganoderma lucidum, Hirsutella sinensis, Caulis spatholobi, aconite, and Bletilla striata were used as herbal medicine. Linggui zhugan-tang, Bofutsushosan, Shenling baizhu powder, Chowiseungcheng-tang, Daesiho-tang, and Yijin-tang were used as prescription. Conclusion Seventeen herbal medicines and six prescriptions associated with meaningful results in weight loss through changes in the gut microbiota, suggest the possibility of treatment and prevention of obesity through herbal medicine.

• International Journal of Industrial Entomology and Biomaterials
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• v.45 no.2
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• pp.126-130
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• 2022

The silkworm is a food material that can simultaneously ingest phytochemicals from mulberry leaves, proteins with essential amino acids, and fatty acids. They are known to have hypoglycemic properties; however, further functional investigation is needed. In this study, four varieties of 3^rd day of fifth instar silkworm with different cocoon colors, namely Baegokjam (BG), Goldensilk (GS), Yeonnokjam (YN), and Juhwangjam (JH), were compared in terms of antioxidant properties and cholesterol-lowering effect. JH, which had the highest polyphenol content (+38% vs. GS, p<0.05) showed high antioxidant efficacy. Treatment with JH also resulted in the lowest cholesterol biosynthesis enzyme activity (28% vs. control, p<0.05). In the animal study, high-fat diet (HFD)-fed mice that were orally administered JH extract for 12 weeks showed lower body weight gain (-10.4% vs. HFD, p<0.05) and serum total cholesterol levels (-12.7% vs. HFD, p<0.05). Comparing the varieties, JH had the highest effect. In future studies, analysis of the active ingredients according to their variety should be done.

• International Journal of Industrial Entomology and Biomaterials
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• v.44 no.2
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• pp.37-43
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• 2022

Silkworm food has been found to be effective for dementia, liver function, lowering blood sugar, and possesses antioxidant properties, which has been attracting attention as a health functional food. In this study, methods for enhancing the functionality of silkworms were explored and the production potential of high-functional silkworms was analyzed. For enhancing antioxidant activity, ascorbic acid, caffeic acid, laminarin, and glutathione were injected or fed to 5th instar silkworms, and the antioxidant activity of silkworm extract was comparatively analyzed. There was no significant change in polyphenol and flavonoid content, but it was confirmed that 2,2-diphenyl-1-picrylhydrazyl radical scavenging ability, superoxide dismutase-like activity, and reducing power were slightly increased after injection of ascorbic acid, caffeic acid, and glutathione. To confirm the increase in antioxidant efficacy through feeding, an inducer was mixed with sucrose and sprayed on mulberry leaves. As a result, the growth rate of silkworms improved and all indicators of antioxidant activity were improved in silkworms fed with ascorbic acid and glutathione. Considering these results, producing high-functional silkworms was deemed possible.

• Journal of Sericultural and Entomological Science
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• v.24 no.2
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• pp.43-54
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• 1983

In a field trial, the influence was studied by measurement of growth and leaf yields and chemical composition (in organic cations and anions and total nitrogen) with two nitrogen dressings (lower nitrogen treatment 25kg and higher nitrogen treatment 75kg urea/10a as the summer fertilizer) after the summer cutting. The results were as follows; 1. With increasingn nitrogen dressing, branch length and weight were enchanced. The fresh weight of leaves was higher to be 273.6kg/10a in the higher nitrogen treatment than in the lower nitrogen treatment on 20 September. 2. The moisture content of leaves lasted above 73% until on 30 August. Afterward it decreased sharply upto 63% on 20 September. In higher nitrogen treatment it was higher about 0.1∼1.8% than in lower nitrogen treatment. The increasing nitrogen dressings combined with leaf condition led to be soft until on 10 October. 3. Dry matter weight of leaves started decreasing around on 10 September, whereas that of branches increased until around 30 September indicating that the dry matter moved to branch and root from leaves. 4. The increase in Ca$\^$2+/ content was particularly evident, whereas the K$\^$+/ and Mg$\^$2+/ decreased with growth. The Ca$\^$2+/ content was much higher in the high nitrogen treatment than in the low nitrogen treatment. 5. With rapid decrease in total nitrogen and water in the leaves around the end of August, the Ca$\^$2+/ and Cl$\^$-/ which were higher in the lower part moved up to the upper part. Whereas the K$\^$+/, H$_2$PO$_4$$\^$-/ and SO$_4$$\^$2-/ which were higher in the upper part moved down to the lower part. 6. Total nitrogen content decreased sharply 3,200me/kg DM to 2,000me/kg DM at the end of August changing the maxmium content of total nitrogen from upper to lower part in the low nitrogen treatment on 12 September and in the high nitrogen treatment on 22 September, and an apex of branches was died and fallen 10 days after respectively. 7. The sum of cation in leaves (∑C) increased from 1400me/kg DM to 1600me/kg DM with growth, wherease that of anions (∑A) was approximatly the same during the whole growing season. As the result, the ionic balance (C-A) increased from 1000me/kg DM to 1200me/kg DM. 8. ∑C, ∑A and (C-A) were higher in the high nitrogen treatment than in the low nitrogen treatment due to be much higher of Ca$\^$2+/ content and higher of NO$\^$-/$_3$, SO$\^$2-/$_4$ and H$_2$PO$_4$$\^$-/ content.

• Journal of Sericultural and Entomological Science
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• v.2
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• pp.49-61
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• 1962

The insect Diplosis mori Yokoyama is causing extensive destruction of mulberry trees in Korea with a resultant loss in silk production. This study was made to determine an effective method of control. Methods and Materials Used Preliminary studies were made to determine more exactly the life cycle of the insect. Based on this information, various control measures were tested, including the use of spray methods with BHC and control of larvae by tilling. Results Obtained 1. Life cycle studies (a) In the Suwon area, this-insect has 5 generations per year. The first starts in the later part of June and the final cycle ends in the later part of September. (b) The adult insects appear about 7: 00-8: 00 P.M. and live for 2-5 days. Females live in longer periods than the male. (c) Larvae lives inside the second and third stipules (A. B.) before mulberry leaf development. They cause extensive damage to the leaves at the point where they are attached to the stem. (d) Weather conditions considerably affect the life cycle. The pupa particularly are affected and not be able to change into the moth stage when there is a long period of no rain. (e) Larvae are large......0.3 to 2.0mm......and are milky-white immediately after hatching but turn to pinkish as the worm matures. The matured worm has a jumping ability up to 15-20cm. The worm burrows into the ground 1.5 to 3.0 cm before changing into the pupal stage. (f) The pupal stage usually lasts 7-8 days, in summer weather conditions and the pupa is surrounded with a coarse cocoon. (g) These insects, as a general rule, overwinter as pupae but sometimes as larvae. 2. Control measures (a) BHC dust applied on the ground seem most effective. It should be done 4-5 days after the worm has burrowed into the ground. For this control, it is recommended that 6kg of a 2% formation Tanbo(l0ares) be used. (b) For the effective spraying against the fly, it is recommended that a formulation of liquid BHC spray terials be used at the rate of 400-600 liters per Tanbo. (c) Tillage methods which provide a cover of soil 5cm or more in depth above infested areas will effect-maively prevent the emergence of the fly from the pupal stage. 3. Conclusions Methods of control against Diplosis mori Yokoyama can be tied more closely to the life cycle of the insect with more effective results. Further studies are needed to complete information on possible controls during or after hibernation. Economic studies on the cost of these control measures are also needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.130-135
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• 2003

Mulberry, Mori folium leaves (ML) and fruits (MF), Lycii fructus (LF), and Panax ginseng have been known to maintain normal blood sugar levels (BSL) in folk medicine. Here we investigated the effects of coated rice with these herb extract to diabetic patients. Alloxan-induced diabetes mellitus (DB) mice (80 mg/kg BW., i.v.) separated into 3 groups. One group received the extract in high dose (6.5 mg/kg B.W.), and another one group received in low dose (1.3 mg/kg B.W.) perorally for 30 days. (+) control received no extracts. (-) control received neither of them. BSL, volume of water consumed (VWC), body weights (BW) of each group were measured and compared. BSL in both of the extracts-received groups got close to normal levels on 4th week after starting the experiments. VWC also showed the same pattern. BSL in (+) control remained high through the experiment periods. BW in (+) control remained high, but those in the extracts-received groups recovered to normal levels. The clinical trials for both of healthy volunteers and DB patients, conducted in a University Hospital, also showed that the rice coated with the extracts could control the BSL. From these results, we suggest that the functional rice with herb extracts could be used as a new alimentotherapy for DB patients.

• Journal of the Korean Society of Costume
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• v.66 no.6
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• pp.67-78
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• 2016

Research on ancient Indonesian 'sacred cloths' is essential since it shows a different perspective into Indonesian identity. Based on its function, the 'sacred cloths' are either made as a medium for religious ceremonies or as a medium for the living and the dead. The consuetude of preparing and creating the 'sacred cloths' are done to achieve the finest 'sacred cloths' worthy to be presented to God. The research aims to analyze the characteristics of ancient Indonesian textiles and to focus on the 'sacred cloths.' The research is divided into two parts, and this paper is the first part. The paper analyzes the characteristics of ancient Indonesian textiles by focusing on the period, religion, region, and color of the 'sacred cloths.' The subsequent research analyzes the characteristics of ancient Indonesian textiles by focusing on the techniques and the patterns of the 'sacred cloths.' In this first part of the main research, the analysis reveals that animism developed in various ways in Indonesia from 500 BC to AD 1800. It was also as kingdoms of Buddhist, Hinduism, and Islam. The changes of religion may differ according to its region. Indonesian regions are divided into six big regions that produce textiles. These islands are Sumatra, Borneo, Java, Celebes, Nusa Tenggara, and Bali. By space and time, the colors of Indonesian textiles represent the ideology of one religion. Indonesia produces primary colors of red, yellow, and blue(RYB). The colors are produced by extracting leaves of Indigo, Indian Mulberry root shell, Sappanwood's branches, Candlenut fruit, Turmeric root, and Mangosteen rind. Indonesia is a religious country, therefore the meaning of creating each 'sacred cloth' shows piety of the maker and the wearer.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.4
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• pp.614-620
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• 2003

Mulberry, Morifolium leaves and fruits, Lycii fructus, and Panax ginseng have been known to maintain normal blood sugar levels in folk medicine. Here we investigated the effects of coated rice (Sodangmi$^{TM}$) with these herb extracts to diabetes mellitus patients. Alloxan-induced diabetic mice (80 mg/kg bw, i.v.) separated into 4 groups. 2 groups received the mixed extracts of these plants (Sodans Extract$^{TM}$) orally everyday for 4 weeks. Positive control received Alloxan except Sodans Extract$^{TM}$. Negative control received neither Alloxan nor Sodang Extract$^{TM}$. Blood sugar levels, volume of water consumed, body weights of each group were measured and compared. Blood sugar levels in the Alloxan and Sodang Extract$^{TM}$-received groups got close to normal levels on 4th week after starting the experiments. Volume of water consumed also showed similar pattern. Blood sugar levels in positive control remained high through the experimental periods. Body weights in positive control remained low, but those in the extracts-received groups recovered to normal levels. The clinical trials for both of healthy volunteers and diabetes mellitus patients also showed Sodangmi$^{TM}$ could control blood sugar level. The blood sugar level decreased since 3rd week after starting to receive Sodangmi$^{TM}$, and the difference between the blood sugar level before and after the meal was decreased significantly by receiving Sodangmi$^{TM}$. From these results, we suggest that the functional rice with herb extracts could be used as a new alimentotherapy for diabetes mellitus patients.llitus patients.

• International Journal of Industrial Entomology and Biomaterials
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• v.8 no.2
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• pp.151-159
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• 2004

A detailed evaluation of relative toxicity of fluoride to die 5th instar larvae of PM and NB$_4$D$_2$ races of silkworm and the effects of lethal, sublethal and prevailing levels of fluoride in groundwater on the growth, economic characters and fecundity of the silkworm, Bombyx mori (Lepidoptera: Bombycidae) were studied. The feeding of mulberry, Morus alba leaves treated with lethal and sublethal doses of fluoride to PM and NB$_4$D$_2$ races of silkworms from the beginning of the 5th instar to the end of the feeding period resulted in significant reduction in growth, single cocoon weight, single shell weight, silk index, average filament length, and fecundity when compared to controls. These manges were more pronounced on exposure to lethal dose than sublethal dose and in general, the changes induced by fluoride were more striking in NB$_4$D$_2$ than PM, indicating the greater resistance of PM to higher fluoride levels. Groundwater quality in sericulturally important villages of Karnataka and Andhra Pradesh States has been studied with special reference to the presence of fluoride. On exposure to dose of prevailing levels in the waters of sericulturally important areas, die changes observed on growth, economic characters and fecundity were slightly lower when compared to controls and the decrease was found to be insignificant (P$\geq$0.05). It was concluded that, though minute dose (4.0 ppm) of fluoride did not have any toxic impact, it is toxic at higher concentrations to silkworms.