• 대한불안의학회지
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• 제3권2호
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• pp.104-109
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• 2007

Objective : In the present study, we evaluated the differences between the skin electric conductance of patients with posttraumatic stress disorder (PTSD) and normal controls in order to determine the possibility of using skin electric conductance as a diagnostic measure. Method : The PTSD group included 14 subjects who were diagnosed with PTSD in St. Mary's Hospital after a motor vehicle accident, and the normal control group included 12 healthy subjects. The conductivity and capacitance of both groups were measured twice, and the data from each group was compared. Results : There was no significant difference in gender, but the patients in the PTSD group were significantly older than those in normal control group. The activity (conductivity) between the left head-left hand, right hand-right head, and right head-left head was significantly elevated in the PTSD group as compared with the normal control group. In addition, the reactivity (capacitance) between the right head-left head, left head-left hand, right hand-left hand, right hand-right foot, right foot-left foot, and left foot-left hand was significantly elevated in the PTSD group. Conclusion : In this study, the skin electric conductance of the patients with PTSD was significantly elevated in comparison with that of the healthy subjects. Although there were some limitations of this study, the results of this study suggested that skin electric conductance can be used to evaluate elevated psychophysiological responses in patients with PTSD. Future studies with more subjects and more structure are needed in order to confirm our results.

• 대한한방내과학회지
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• 제26권1호
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• pp.252-264
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• 2005

This concerns three patients diagnosed as lateral medullary infarction from cerebral infarction of the brain stem and hospitalized. They were diagnosed and treated for 手足??(paralysis of extremities), 痺症(bi syndrome), 麻木(numbness), 不仁(akinesia), 眩暈(Vertigo) through Oriental Medicine. Improvement in both sense disorder and motor disorder was seen and is therefore reported here. To detect symptoms of a brain stem disorder clinically, pathological symptoms must be isolated and the patient must be screened through radiological and neorological examination. If this is properly and carefully done from the first stage, and according to this diagnosis, with the cycle of the disease considered, a treatment plan can be laid. Modem Medicine offers easy diagnosis for cerebro-vascular disease, but the treatment is less effective than that offered by Oriental Medicine. This report is given with a plea for further research and more reportage of clinical cases of cerebro-vascular disease treated through Oriental Medicine.

• 대한소아치과학회지
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• 제25권3호
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• pp.525-532
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• 1998

치과의사는 자폐인의 치료시 자폐증의 정도와 의학적 관리가 필수적인 질환, 내과적 병력, 현재 환자가 복용하고 있는 약물등을 고려하여 이에 따라 적절한 행동조절 방법을 선택하여야 한다. 행동조절 방법의 선택시 술자가 선호하는 방법을 우선하기 보다는 환자의 상태와 치과치료시 환자와 보호자가 받는 스트레스를 최우선으로 고려하는 것이 필요하다. 환자의 현증에 대한 적절한 행동조절하의 치과치료도 중요하지만, 그보다 더 중요한 것은 환자가 거부감을 느끼지 않고 치과에 내원할수 있도록 훈련시키는 것과 지속적인 구강위생 관리이므로 보호자를 위한 구강위생 관리교육 및 주기적인 내원에 의한 관리가 필요하다고 생각된다.

• 동의생리병리학회지
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• 제21권6호
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• pp.1663-1669
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• 2007

Acute transverse myelitis(ATM) is defined as an acute intramedullary dysfunction of the spinal cord, ascendng or static involving both halves of the cord and appearing without any history of previous neurological diseases due to traumatic accident, tumor of all kind, encephalitis and of course excluding all possible viral, bacterial and fungal infection. It is mainly characterized by acute motor disorder of both limbs in respect to which spinal segments are affected as well as sensory disorder and dysuria & dyschezia. The exact cause is unknown, however it is recently suggested that immunological factors are highly involved. It has been reported by several reliable sources that it is often accompanied by immunological diseases such as systemic lupus erythematosus(SLE). As treatments non steroid anti-inflammatory drugs(NSAIDS) are primarily recommended as to steroids, limited doses are injected only with the proper prescription from the physician. Operative methods are not options as traumatic accidents and tumors are excluded as factors. To enhance muscle strength and prevent articular contracture physical therapy and passive exercise is imperative. The following patient whose chief complaints were mainly about hypoesthesia of Rt. lower limb and stiffness of phalanges of both fingers as well as to weakness of lower extermity. Therefore it has been diagnosed as arthalgia syndrome. In oriental medicine factors such as wind evil heat-evil, dampness-heat evil, cold evil cause the arthalgia syndrome. In this case the patient was diagnosed as dampness-heat evil and herbal medicine Chunglijagam-Tang and Dong-Qi acupuncture was applied to treat bladder disorder.

• 생물정신의학
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• 제27권2호
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• pp.42-57
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• 2020

Electroconvulsive therapy (ECT) is indicated for various mental disorders (e.g., major depressive disorder, schizophrenia, and bipolar disorder) and the behavioral and psychological symptoms of dementia in elderly patients. Furthermore, ECT is a useful first-line treatment in emergency and crisis situations such as suicide risk, violent behavior, catatonia, and food refusal, which are more frequent in elderly patients. ECT is also effective in the treatment of the motor symptoms of neurological disorders, such as Parkinson's disease and Huntington's disease. Due to the high risk of various physical diseases, the comorbid physical conditions of elderly patients should be individually controlled to optimize ECT treatment. Compared to young adults, in elderly patients the seizure threshold is higher, the seizure duration is shorter, and the anesthetic dose is lower. On the contrary, the response rate in the elderly is both faster and higher. Considering potential cognitive decline and the prevention of further deterioration of cognitive function in elderly patients, in the absence of significant comorbidities, twice weekly sessions and right unilateral electrode placement with a lower seizure threshold and less cognitive effect are preferred to bilateral electrode placement, which has a high risk of adverse cognitive effects. After an acute course of ECT, continuation and maintenance of ECT, combined with prescription of therapeutic drugs, may prevent possible relapse or recurrence of mental disorders. In conclusion, ECT can be used to treat mental disorders in elderly adults, with safety and effectiveness comparable to that in young adults.

• 재활치료과학
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• 제5권1호
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• pp.77-87
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• 2016

목적 : 상지 협응 움직임을 기반으로 한 과제중심적 접근 훈련이 발달성 협응 장애아동의 한글 글씨쓰기 능력에 미치는 영향을 알아보며 각 접근이 한글 글씨 쓰기 수행의 질과 글씨쓰기 준비기술에 미치는 영향을 비교하고자 한다. 연구방법 : 본 연구는 5~10세의 발달성 협응장애 아동 40명을 대상으로 무작위 추출을 통해 두 집단으로 나뉘어 사전-사후 검사로 진행하였다. 두 집단은 과제중심접근 중재군과 과정중심접근 중재군으로 5주 동안 40분씩 주 2회 중재를 받았다. 글씨쓰기 수행은 한글 자모 쓰기 검사로 측정하고, 글씨쓰기 준비요소인 상지 운동 기능, 시 지각 기능과 시 운동기능은 각각 운동 유창성 평가(Bruininks-Oseretsky Test of Motor Proficiency-2: BOT-2)중 미세운동조절의 하위검사 일부, 한국판 시 지각 발달 검사(Korean-Developmental Test of Visual Perception-2: K-DTVP-2), 개정된 시 운동기술 평가(Test of Visual Motor Skills-Revised: TVMS-R)로 평가하였다. 고찰 : 본 연구는 과제중심접근법을 적용하여 발달성 협응 장애아동의 글씨쓰기 수행도를 향상시킨다는 임상적 근거를 제공하는데 의의가 있다. 또한 과정중심접근법과 과제중심접근법이 글씨쓰기 준비기술의 향상에 어떠한 영향을 끼치는 지에 대한 결과를 확인하여 보다 효과적인 글씨쓰기 중재방법을 제시하는 초석이 될 수 있을 것이라 생각한다.

• 대한임상검사과학회지
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• 제50권2호
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• pp.211-215
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• 2018

이 연구의 목적은 운동피질 주변의 뇌종양 환자를 대상으로 수술 중 피질척수로를 보존하고 운동 능력을 더 정확하게 평가하기 위함이다. 경두개운동유발전위는 위양성(false positive)과 위음성(false negative)이 혼재하는 검사이기 때문에 수술 중 검사상 파형의 변화가 없었다 할 지라도 검사의 내용을 완전히 신뢰할 수 없다. 보다 자세한 검사를 위해 대뇌피질을 선택적으로 자극할 수 있는 직접피질자극검사를 시행하였다. 직접피질자극 검사를 시행한 2케이스 에서는 수술 중 피질이 담당하는 부위를 찾고 지속적으로 진폭의 변화를 확인하며 검사할 수 있어 운동경로를 보존하며 수술 할 수 있었다. 하지만 직접피질 자극검사를 시행하지 않고 경두개운동유발전위 검사만을 시행한 환자에서는 수술 후 환자의 운동 능력이 감소되는 것을 경험할 수 있었다. 위와 같은 결과를 볼 때 직접피질자극 검사는 매우 유용한 검사이고 뇌종양 수술 시 경두개운동유발전위 검사와 병행하여 환자에게 올 수 있는 후유장애를 줄일 수 있는 방법이다.

• 동의생리병리학회지
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• 제23권4호
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• pp.898-902
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• 2009

The aim of this study is to report the improvement after the Oriental medical treatment about a paraplegic patient caused by spinal cord injury. The paraplegia caused by spinal cord injury was the result of falling down. So we diagnosed it as Eohyeol(瘀血), Wei symptom(痿證), Urinary retention(癃閉) in Oriental medical system and applied herbal medicine, acupuncture, moxibustion, physical exercise to the patient for 42days. We evaluate the clinical effect of the treatment with VAS and motor/sensory function score of the body and lower extremities. After the Oriental medical treatment, we achieved the effective result on impairment in motor and sensory function of the paraplegic patient. And also we got the improvement of urinary disorder and pain. The more clinical study about paraplegic patient caused by spinal cord injury may be needed.

• 대한의용생체공학회:의공학회지
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• 제17권3호
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• pp.319-326
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• 1996

Clinical myography(EMG) is a technique for diagnosing neuromuscular disorders by analyzing the electrical signal that can be records by needle electrode during a muscular contraction. The EMG signal arises from electrical discharges that accompany the generation of force by groups of muscular fiber, and the analysis of EMG signal provides symptoms that can distinguish disorder of mLecle from disor- ders of nerve. One of the methods for analysis of EMG signal is to separate the individual discharge-the motor unit action potentials(MVAPS) - from EMG signal. But we can only observe the EMG signal that is a superimposed version of time delayed MUAPS. To obtain the information about MUAP(, i.e., position, firing number, magnitude etc), first of all, a method that can separate each MUAP from the EMG signal must be developed Although the methods for MUAP separation have been proposed by many researcherl they have required heavy computational burden. In this paper, we proposed a new method that has less computational burden and performs more reliable separation of superimposed EMG signal using wavelet filter which has multiresolution analysis as major property. As a result, we develope the separation algorithm of superimposed EMG signal which has less computational burden than any other researchers and exacutes exact separation process. The performance of this method has been discussed in the automatic resolving procedure which is neccessary to identify every firing of every motor unit from the EMG pattern.

• Journal of mucopolysaccharidosis and rare diseases
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• 제3권2호
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• pp.41-43
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• 2017

Prader-Willi syndrome (PWS) is a genetic disorder that is considered, especially on child, to cause poor feeding, hypotonia, failure to thrive, developmental delay and hypogonadism which is known to affect between 1 in 10,000 and 30,000 people. The children with PWS are viewed as affected by growth hormone (GH) insufficiency, although the exact mechanisms of GH deficiency are not fully understood. However, the benefits of GH treatment in children with PWS are well established. Myers, et al. (2006), Grugni, et al. (2016) indicated its positive effects on linear growth, body composition, motor function, respiratory function and psychomotor development. Despite of its effectiveness and advantages had been well known and proven in many other studies, there is only one recombinant GH product that is approved for PWS in Korea, $Genotropin^{(R)}$, till now. A phase III clinical study of GH treatment with $Eutropin^{TM}$, in 34 Korean PWS children is in progress, which is expected to have comparable effects and safety profile with the active control by assessing auxological changes such as height standard deviation score, body composition changes such as lean body mass and percent body fat, motor and cognitive development using Bayley scale, and safety profiles.