• Title/Summary/Keyword: Mortality Improvement

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A Case Report of Lupus Nephritis in a Child Patient Treated with Jasinwhalhyul-tang and Steroid Therapy (자신활혈탕(滋腎活血湯)과 스테로이드 병합요법으로 관해를 보인 소아 낭창성 신염 환자 1예)

  • Chang, Sun-Kyu;Choi, Jeong-Sik;Ann, So-Hyun;Cho, Chung-Sik;Kim, Cheol-Jung
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.819-826
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    • 2008
  • In childhood systemic lupus erythematosus patients, renal involvement is closely related to mortality and morbidity of the disease. Therefore early diagnosis and treatment are essential to improving prognosis. We saw a child who had hematuria, albuminuria, anorexia, fatigue, and light hyper sensitiveness. He was diagnosed as lupus nephritis (WHO Class II+IV) and treated with ACE inhibitor and steroid therapy for 12 months. However, clinical improvement was not shown. So we treated him with herbal formula (Jasinwhalhyul-tang: Zishenhuoxue-tang) and steroid therapy. After 17 months of treatment, hematuria disappeared and clinical symptoms and albuminuria had improved significantly.

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A Research Review of Village Chicken Production Constraints and Opportunities in Zimbabwe

  • Mapiye, C.;Mwale, M.;Mupangwa, J.F.;Chimonyo, M.;Foti, R.;Mutenje, M.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.11
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    • pp.1680-1688
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    • 2008
  • Development of village chicken production can be a sustainable way of helping to meet the welfare needs of rural populations and raise their living standards. There is a dearth of information on research conducted to characterize, understand and develop the village chicken production systems in Zimbabwe. This review focuses on constraints, opportunities and research needs for the improvement of village chicken productivity in Zimbabwe. Village chicken production in Zimbabwe is extensive and dominated by indigenous chickens that exhibit remarkable adaptation to local environments. The multitude functions of village chickens, which include the provision of high quality protein meat and eggs, cash through sales and socio-cultural roles, are discussed in detail. Human gender aspects in village chicken production are highlighted. The factors that hamper village chicken productivity are reviewed together with opportunities and research needs. The major constraints include shortage of feed, poor health and housing management. Any improvements in these constraints may lead to sustainable increase in village chicken productivity.

Study on Kidney Toxicity of BDR-29 for Treatment Vascular Diseases in Rats (혈관질환 억제 효능이 있는 BDR-29의 백서 신장 독성연구)

  • Kim, Eun-Ju;Kang, Dae-Gill;Lee, An-Sook;Choi, Deok-Ho;Cho, Kuk-Hyun;Kim, Sung-Yun;Lee, Ho-Sub
    • Herbal Formula Science
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    • v.16 no.2
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    • pp.163-169
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    • 2008
  • The kidney toxicities of BDR-29 used for improvement of the vascular diseases, was examined using male and female Sprague-Dawley rats. The male and female rats were divided into 4 groups for intragastrical treatment with doses of 0, 5, 50, and 500 mg/kg/day for 13 weeks, respectively. In all male and female rats treated with BDR-29, no mortality and gross pathological findings were shown for 13 weeks. There substantially was no change in body weight in all rats with treatment of BDR-29. The renal functional parameters including urinary volume, urine osmolality, electrolytes excretory rate, creatinine clearance, and solute-free water reabsorption were not exchanged in all rats treated with BDR-29. Taken together, these results suggest that BDR-29 has no toxicity on kidney in all male and female rats.

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PIV measurement of oscillatory flow in a micro-channel as a bronchiole model

  • LEE Won-je;KAWAHASHI Massaki;HIRAHARA Hiroyuki
    • 한국가시화정보학회:학술대회논문집
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    • 2004.12a
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    • pp.125-134
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    • 2004
  • The improvement of artificial respiration method has brought about the decrease in mortality of pulmonary diseases patients. Various respiratory curative methods, inclusive of HFOV (High Frequency Oscillatory Ventilation), have been developed for more effectual and less harmful management of acute respiratory failure. However, the mechanism of gas transfer and diffusion in a bronchiole has not yet been clarified in detail. As a first approach to the problem, we measured oscillatory flows in a Y-shaped micro-channels as bronchiole model by micro Particle Image Velocimetry(micro PIV). In order to establish the fundamental technique of PIV measurements on oscillatory air flow in a micro-channel, we used about 500-nm-diameter incense smoke particles, a diode laser, a high speed camera including an objective lens, and a HFOV, which is effective technique for medical care of pulmonary disease patients, especially, infants. The bronchiole model size is that parent tube is $500\{mu}m$ width and $500\{mu}m$ depth, and daughter tubes are $450\{mu}m$ width and $500\{mu}m$ depth. From this study made on the phenomenon of fluid in micro size bronchus branch of a lung, we succeeded to get time series velocity distribution in a micro scale bronchial mode. The experimental results of velocity distribution changing with time obtained by micro PIV can give fundamental knowledge on oscillatory airflow in micro-channel.

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Mid-term Experience with the Pyrolytic Carbon Bileaflet Mechanical Valves (쌍엽 기계판막에대한 임상연구)

  • 박계현
    • Journal of Chest Surgery
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    • v.25 no.2
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    • pp.137-148
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    • 1992
  • Until March 1991, 435 St. Jude Medical valves and 330 CarboMedics valves were implanted in 358 and 251 patients, respectively. 300 patients were male and 309 were female with the mean age of 35.6 years[from 2 month to 68 years]. 458 valves were implanted in the mitral, 272 in the aortic, 25 in the tricuspid, and 10 in the pulmonic position. Postoperatively, all patients except for very young patients were given coumadin with or without dipyridamole for anticogulation Operative mortality was 7.3%[45 deaths per 618 operations]. A total follow-up of 1244.8 patient-years was achieved for the operative survivors with a follow-up rate of 96.8%, [mean follow-up period=26.3 months /patient, ranging from 1 to 80 months]. Functional improvement was evident; 66.7% of these patients were in NYHA functional class III or IV preopratively, whereas 98.4% are in class I or II pos-toperatively. There occurred 13 late deaths[7 valve-related] and 55 valve-related complications. Linearized rates of late death and valve-related complications were 1.0%/ patient-year, 4.42%/patient-year, respectively. Rates of thromboembolism, anticoagluation-related hemorrhage were 1.12%/patient-year, 1.69% /patient-year, respectively. Actuarial survival at 5 years is 96.0% and complication-free survival at 5 years is 83.9%. No difference in survival and incidence of complications was found between the St. Jude and CarboMedics valves. On the basis of this experience, we believe that the pyrolytic carbon bileaflet mechanical valves are safe and preferable choice among current valve prostheses.

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Neonatal Gastrointestinal Perforation (신생아 위장관천공)

  • Kim, Seong-Chul;Kim, In-Koo
    • Advances in pediatric surgery
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    • v.3 no.1
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    • pp.41-46
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    • 1997
  • Perforation of the gastrointestinal tract in neonatal period has been associated with a grim prognosis. Recently there has been some improvement in survival. To evaluate the remaining pitfalls in management, 19 neonatal gastrointestinal perforation cases from May 1989 to July 1996 were analysed retrospectively. Seven patients were premature and low birth weight infants. Perforation was most common in the ileum(56.3%). Mechanical or functional obstruction distal to the perforation site was identified in 7 cases; Hirschsprung's disease 3, small bowel atresia 3, and anorectal malformation 1. These lesions were often not diagnosed until operation. Five cases of necrotizing enterocolitis and 1 of muscular defect were the other causes of perforation. In six cases, the cause of the perforation was not identified. Perinatal ischemic episodes were associated in five cases. Overall mortality was 15.1%. Because a considerable number of gastrointestinal perforations resulted from distal obstruction, pediatric surgeon should be alert for early identification and intervention of gastrointestinal obstruction, particularly in patients that are premature and have a history of ischemia.

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Current Status of Korean Premature Infant Care and its Prospective (한국 미숙아 관리의 현황과 전망)

  • Shin Yeong-Hee
    • Child Health Nursing Research
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    • v.9 no.1
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    • pp.96-106
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    • 2003
  • Advances in neonatal care system and research have resulted in an increased survival rate among low birth weight infants in the industrialized countries. Recent Korean neonatal mortality and morbidity statistics, and current status of Korean neonatal intensive care facilities were reviewed here for the sake of future improvement and research. Morbidity statistics revealed that perinatal diseases accounted for 80% of the death of premature infants implying the possibility of its reduction by the vigorous prenatal care service in future.On the basis of extensive studies of nutritional support and growth rate of premature infants, commercial formulas for premature infants have been developed and various aspects of feeding techniques are standardized. However, problem of growth deficit of premature infants remains unsolved as medical problem. NICU specialists are challenged with the tasks of prenatal education or provision of care that minimizes the neurodevelopmental problems seen in preterm infants, various short-term outcome researches have been reported and those are reviewed here to promote research interest in the field of neonatal nursing. Systemic long-term outcome studies are also awaited in Korea for the formulation of welfare policy in future. Nursing science has to embrace all these interdisciplinary studies as their own research field in collaboration with neonatologist, nutritionist, rehabilitation therapist, social workers and teachers.

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A Basic Study on the Risk Assessment of Domestic Construction Companies (국내 건설업체의 위험성평가 실태조사 기초 연구)

  • Park, Hwan-Pyo;Han, Jae-Goo
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2019.05a
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    • pp.240-241
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    • 2019
  • Construction disasters have more distinctive characteristics than other industrial disasters. Since it is likely that construction disasters will spread to severe accidents, the accident mortality rate is very high compared to the disaster incidence rate. Therefore, the purpose of this study is to compare and analyze the operation status of construction risk assessment by domestic large and medium sized construction companies to prepare improvement direction of risk assessment system. The survey results for safety management experts of construction companies are as follows: Large companies have developed and utilized risk assessment systems in their respective companies, while small and medium construction companies have developed and evaluated risk factors through the Excel program. Rather than performing risk assessment tasks based on historical safety accident data, construction companies have limitations in developing risk factors and preparing solutions with suppliers for each major construction. Therefore, it is necessary to prepare a risk assessment system in the future by analyzing the types of safety accidents, such as the safety accident data of each company as well as the safety accident data.

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Noncommunicable Diseases: Current Status of Major Modifiable Risk Factors in Korea

  • Kim, Hyeon Chang;Oh, Sun Min
    • Journal of Preventive Medicine and Public Health
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    • v.46 no.4
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    • pp.165-172
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    • 2013
  • A noncommunicable disease (NCD) is a medical condition or disease that is by definition non-infectious and non-transmissible among people. Currently, NCDs are the leading causes of death and disease burden worldwide. The four main types of NCDs, including cardiovascular disease, cancer, chronic lung disease, and diabetes, result in more than 30 million deaths annually. To reduce the burden of NCDs on global health, current public health actions stress the importance of preventing, detecting, and correcting modifiable risk factors; controlling major modifiable risk factors has been shown to effectively reduce NCD mortality. The World Health Organization's World Health Report 2002 identified tobacco use, alcohol consumption, overweight, physical inactivity, high blood pressure, and high cholesterol as the most important risk factors for NCDs. Accordingly, the present report set out to review the prevalence and trends of these modifiable risk factors in the Korean population. Over the past few decades, we observed significant risk factor modifications of improved blood pressure control and decreased smoking rate. However, hypertension and cigarette smoking remained the most contributable factors of NCDs in the Korean population. Moreover, other major modifiable risk factors show no improvement or even worsened. The current status and trends in major modifiable risk factors reinforce the importance of prevention, detection, and treatment of risk factors in reducing the burden of NCDs on individuals and society.

Bilateral Ureteral Obstruction Related to Pelvic Rhabdomyosarcoma Presenting with Acute Kidney Injury: A Case Report

  • Han, Sanghoon;Han, Kyoung Hee
    • Childhood Kidney Diseases
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    • v.23 no.2
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    • pp.116-120
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    • 2019
  • Bilateral renal obstruction is a rare critical condition, requiring a prompt diagnostic approach and treatment to restore the renal function. The most commonly observed obstructive uropathy in children is congenital malformation, such as posterior urethral valves and bilateral ureteropelvic junction obstruction. Malignant pelvic masses obstructing the ureter are widely reported in adults but are rarely observed in children. The treatment of ureteral obstruction related to pelvic malignancy is a therapeutic challenge with a median survival duration of 3-7 months in adults; however, pediatric patients with pelvic malignancy leading to ureteral obstruction had better outcomes, with a reported 5-year mortality rate of 20%, than the adult patients. Here, we report a rare case of bilateral ureteral obstruction associated with pelvic rhabdomyosarcoma presenting with acute kidney injury treated by ureteral diversion with double J stent, and concommittent emergency hemodialysis, leading to restoration of good renal function. We suggest that bilateral ureteral obstruction should be released as soon as possible using surgical or interventional approach to minimize the obstruction period, and subsequential chemotherapy may contribute to improvement of survival and recovery of renal function.