DOI QR코드

DOI QR Code

Bilateral Ureteral Obstruction Related to Pelvic Rhabdomyosarcoma Presenting with Acute Kidney Injury: A Case Report

  • Han, Sanghoon (Department of Internal Medicine, Division of Oncology, Jeju National University School of Medicine) ;
  • Han, Kyoung Hee (Department of Pediatrics, Division of Pediatric Nephrology, Jeju National University School of Medicine)
  • Received : 2019.07.11
  • Accepted : 2019.09.09
  • Published : 2019.10.31

Abstract

Bilateral renal obstruction is a rare critical condition, requiring a prompt diagnostic approach and treatment to restore the renal function. The most commonly observed obstructive uropathy in children is congenital malformation, such as posterior urethral valves and bilateral ureteropelvic junction obstruction. Malignant pelvic masses obstructing the ureter are widely reported in adults but are rarely observed in children. The treatment of ureteral obstruction related to pelvic malignancy is a therapeutic challenge with a median survival duration of 3-7 months in adults; however, pediatric patients with pelvic malignancy leading to ureteral obstruction had better outcomes, with a reported 5-year mortality rate of 20%, than the adult patients. Here, we report a rare case of bilateral ureteral obstruction associated with pelvic rhabdomyosarcoma presenting with acute kidney injury treated by ureteral diversion with double J stent, and concommittent emergency hemodialysis, leading to restoration of good renal function. We suggest that bilateral ureteral obstruction should be released as soon as possible using surgical or interventional approach to minimize the obstruction period, and subsequential chemotherapy may contribute to improvement of survival and recovery of renal function.

Keywords

References

  1. Andreoli SP. Acute kidney injury in children. Pediatr Nephrol 2009;24:253-63. https://doi.org/10.1007/s00467-008-1074-9
  2. Andreoli SP. Clinical evaluation of acute kidney injury in children. In: Avner ED, Harmon WE, Niaudet P, Yoshikawa N. editors. Pediatric nephrology. 6th ed. Springer, 2009:1603-18.
  3. Meir DB, Inoue M, Gur U, Livne PM, Yaniv Y, Tiedeman K, et al. Urinary diversion in children with pelvic tumors. J Pediatr Surg 2004;39:1787-90. https://doi.org/10.1016/j.jpedsurg.2004.08.003
  4. Kouba E, Wallen EM, Pruthi RS. Management of ureteral obstruction due to advanced malignancy: optimizing therapeutic and palliative outcomes. J Urol 2008;180:444-50. https://doi.org/10.1016/j.juro.2008.04.008
  5. Alexander A, Weber B, Lorenzo A, Keays M, El-Ghazaly T, Bagli DJ, et al. Hydronephrosis in children with abdominal and pelvic neoplasms: outcome and survival analysis of a single center pediatric oncology series. J Urol 2011;186:1705-9. https://doi.org/10.1016/j.juro.2011.04.010
  6. Crist WM, Anderson JR, Meza JL, Fryer C, Raney RB, Ruymann FB, et al. Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J Clin Oncol 2001;19:3091-102. https://doi.org/10.1200/JCO.2001.19.12.3091
  7. Jeong IG, Han KS, Joung JY, Seo HK, Chung J. The outcome with ureteric stents for managing non-urological malignant ureteric obstruction. BJU Int 2007;100:1288-91. https://doi.org/10.1111/j.1464-410X.2007.07172.x
  8. Asakawa J, Iguchi T, Tamada S, Ninomiya N, Kato M, Yamasaki T, et al. Treatment outcomes of ureteral stenting for malignant extrinsic ureteral obstruction: a comparison between polymeric and metallic stents. Cancer Manag Res 2018;10:2977-82. https://doi.org/10.2147/CMAR.S172283
  9. Bianchi D, Vespasiani G, Bove P. Acute kidney injury due to bilateral ureteral obstruction in children. World J Nephrol 2014;3:182-92. https://doi.org/10.5527/wjn.v3.i4.182
  10. Alobaid AS. Mucinous cystadenoma of the ovary in a 12-yearold girl. Saudi Med J 2008;29:126-8.
  11. McNamara TE, Butkus DE. Nephrostomy in Patients With Ureteral Obstruction Secondary to Nonurologic Malignancy: Obstructive Uropathy in Malignant Disease. Arch Intern Med 1980;140:494-7. https://doi.org/10.1001/archinte.1980.00330160054026
  12. Lutaif N, Yu L, Abdulkader R. Factors influencing the non-recovery of renal function after the relief of urinary tract obstruction in women with cancer of cervix. Ren Fail 2003;25:215-23. https://doi.org/10.1081/JDI-120018722