• Parasites, Hosts and Diseases
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• 제50권2호
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• pp.143-146
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• 2012

Diphyllobothrium latum infections in 4 young Korean men detected from 2008 to 2012 are presented. Three were diagnosed based on spontaneously discharged strobila of the adult worm in their feces, and 1 case was diagnosed by finding the worm at colonoscopy examination in a local clinic. The morphologic characteristics of the gravid proglottid and eggs were consistent with D. latum. All patients were treated with praziquantel 15 mg/kg, and follow-up stool examinations were done at 2 months after the medication. The main clinical complaints were intermittent gastrointestinal troubles such as indigestion, abdominal distension, and spontaneous discharge of tapeworm's segments in their feces. The most probable source of infection was the flesh of salmon or trout according to a patient's past history. These are the 45th to 48th recorded cases diagnosed by the adult worm in the Republic of Korea since 1971.

• 대한후두음성언어의학회지
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• 제11권1호
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• pp.64-68
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• 2000

Background and Objectives : To assess the role of altered vocal function in transient voice change after short-term endotracheal intubation, we evaluated acoustic parameters, aerodynamic parameters, and laryngoscopic characteristics preoperatively and postoperatively. Materials and Methods : Vocal function of 10 patients undergoing tympanoplasty and mastoidectomy using general anesthesia and endotracheal intubation were studied preoperatively, at 1day and 7 days after extubation. Acoustic analysis, aerodynamic study, and telescopic examination were used to assess vocal function. Results : In acoustic parameters, there was no significant difference between preoperative and postoperative measures. However, in subglottic pressure, ere was a significant decrease at 1 day after extubation and this change was return to preoperative value at 7 days after extubation. MPT(Maximal Phonation Time), MER(Mean flow Ratio), and VC(Vital Capacity) were decreased 1 day after extubation but did not show statistically significant change. Three of 10 patients manifested a vocal fold edema and injection 1 day after extubation. Conclusions : Subglottic pressure revealed a significant decrease at 1 day after extubation. And this change was correlated with laryngeal morphologic change and decrement in pulmonary function.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권3호
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• pp.211-220
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• 2007

Objective: In organotypic culture of immortalized human oral keratinocytes (IHOK), the change of the growth and differentiation was investigated according to the fibroblast type and the involvement of mitogen-activated protein (MAP) kinase. Materials & Methods: IHOK was cultured three dimensionally with gingival fibroblast (GF), dermal fibroblast (DF) and immortalized gingival fibroblast (IGF). We characterized biologic properties of three dimensionally reconstructed IHOK by histological, immunohistochemical, and Western blot analysis. We also investigated whether MAP kinase pathway was involved in epithelial-mesenchymal interaction by Western blot analysis. Results: The best condition of three dimensionally cultured IHOK was the dermal equivalent consisting of type I collagen and IGF. IGF increased the expression of more proliferating cell nuclear antigen (PCNA), involucrin than GF and DF in response to co-culture with IHOK. Extracellularly regulated kinase (ERK) pathway was activated in organotypic co-culture with IGF. Conclusion: The organotypic co-culture of IHOK with dermal equivalent consisting of type I collagen and IGF resulted in excellent morphologic and immunohistochemical characteristics and involved ERK pathway. The epithelial-mesenchymal interaction was activated according to the fibroblast type.

• PNF and Movement
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• 제4권1호
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• pp.51-62
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• 2006

Purpose : The purposes of this study were to test the effect of proprioceptive and vestibular sensory input on expression of BDNF after traumatic brain injury in the rat. Subject : The control group was sacrificed at 24 hours after traumatic brain injury. The experimental group I was housed in standard cage for 7 days. The experimental group II was housed in standard cage after intervention to proprioceptive and vestibular sensory(balance training) for 7 days. Method : Traumatic brain injury was induced by weight drop model and after operation they were housed in individual standard cages for 24 hours. After 7th day, rats were sacrificed and cryostat coronal sections were processed individual1y in goat polyclonal anti-BDNF antibody. The morphologic characteristics and the BDNF expression were investigated in injured hemisphere section and contralateral brain section from immunohistochemistry using light microscope. Result : The results of this experiment were as follows: 1. In control group, cell bodies in lateral nucleus of cerebellum, superior vestibular nucleus, purkinje cell layer of cerebellum and pontine nucleus changed morphologically. 2. The expression of BDNF in contralateral hemisphere of group II were revealed. 3. On 7th day after operation, immunohistochemical response of BDNF in lateral nucleus, superior vestibular nucleus, purkinje cell layer and pontine nucleus appeared in group II. Conclusion : The present results revealed that intervention to proprioceptive and vestibular sensory input is enhance expression of BDNF and it is useful in neuronal reorganization improvement after traumatic brain injury.

• PNF and Movement
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• 제5권1호
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• pp.9-17
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• 2007

Purpose : The purpose of this study was to test the effect of balance training for proprioceptive and vestibular sensory stimulation and therapeutic environment on expression of BDNF after traumatic brain injury in the rat. Subject : Twelve Sprague-Dawley rats were randomly assigned into group I and group II. After traumatic brain injury, group I was housed in standard cage for 7 days. Group II was housed in therapeutic cage after balance training for 7 days. Method : Traumatic brain injury was induced by weight drop model and after operation they were housed in individual standard cages for 24 hours. After 7th day, the rats were sacrificed and cryostat coronal sections were processed individually in goat polyclonal anti-BDNF antibody. The morphologic characteristics and the BDNF expression were investigated in injured hemisphere section from immunohistochemistry using light microscope. Result : Immunohistochemical response of BDNF in lateral nucleus, purkinje cell layer, superior vestibular nucleus and pontine nucleus appeared very higher in group II than in group I Conclusion : The present result revealed that simultaneously application of balance training for proprioceptive and vestibular sensory stimulation input and therapeutic environment in traumatic brain injured rats is enhance expression of BDNF and it is facilitates neural plasticity.

• 대한수의학회지
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• 제40권2호
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• pp.339-343
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• 2000

Isolation and identification, prevalence and density of Setaria microfilariae(mf) were investigated in the blood of 406 cattle slaughtered at the abatoirs in Yungnam province from February 1999 to March 2000. Nine ml of blood from the jugular vein was collected in a test tube including EDTA respectively. The blood was mixed(10 : 1) with 0.2% Saponin in saline solution. This mixture was diluted again(1 : 10) with saline solution and stirred. This diluted mixture was filtered using Millipore membrane filter with a pore size of $3.0{\mu}m$. Mf were recovered from the membrane in saline solution. Mf isolated were identified as Setaria digitata on the basis of morphologic characteristics. Infection rate of the mf of total 406 cattle was revealed as 6.40%. Seasonal prevalences of the mf were presented 9.46%(7/74) in Autumn, 7.05%(11/156) in Summer, 4.65%(4/86) in Winter and 4.44%(4/90) in Spring respectively. Average density of the mf of every 9ml blood in 26 positive cattle was revealed as 170(2-641) worms. Seasonal densities of the mf of 9ml blood were presented average 361(160-641) worms in Autumn, 205(16-620) worms in Summer, 108(6-204) worms in Spring, 6(2-11) worms in Winter respectively.

• 폴리머
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• 제37권1호
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• pp.100-112
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• 2013

현재 일반화되어 있는 pilot scale의 복합체 생산설비에서 용융 삽입법으로 nylon 66/Cloisite 93A 나노복합체의 상용화 가능성을 확인하였으며, nylon 66에 Cloisite 93A 도입으로 인장 및 굴곡응력에 대한 강도와 탄성률이 향상되었고, 형태학적 및 결정화 거동의 분석을 통해 Cloisite 93A 함량, nylon 66 점도 및 그에 따른 결정화 거동이 주요 영향요소임을 확인하였다.

• Macromolecular Research
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• 제11권1호
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• pp.2-8
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• 2003

The self-assembly of polymers can lead to supramolecular systems and is related to the their functions of material and life sciences. In this article, self-assembly of Langmuir-Blodgett (LB) films, polymer micelles, and polymeric nanoparticles, and their biomedical applications are described. LB surfaces with a well-ordered and layered structure adhered more cells including platelet, hepatocyte, and fibroblast than the cast surfaces with microphase-separated domains. Extensive morphologic changes were observed in LB surface-adhered cells compared to the cast films. Amphiphilic block copolymers, consisting of poly(${\gamma}$-benzyl L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) [or poly(N-isopropylacrylamide) (PNIPAAm)] as the hydrophilic one, can self-assemble in water to form nanoparticles presumed to be composed of the hydrophilic shell and hydrophobic core. The release characteristics of hydrophobic drugs from these polymeric nanoparticles were dependent on the drug loading contents and chain length of the hydrophobic part of the copolymers. Achiral hydrophobic merocyanine dyes (MDs) were self-assembled in copolymeric nanoparticles, which provided a chiral microenvironment as red-shifted aggregates, and the circular dichroism (CD) of MD was induced in the self-assembled copolymeric nanoparticles.

• 한국수산과학회지
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• 제52권4호
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• pp.418-423
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• 2019

We report the first occurrence of Ophichthus erabo (Jordan and Snyder, 1901) collected in the waters around Jeju Island. The morphologic characteristics of this species include rich brown semicircular spots distributed on the head, the back, and the dorsal fins. Ophichthus erabo has a similar body color to Ophichthus polyophthalmus but can be clearly distinguished from the latter by the number of vertebrae (152-155 in O. erabo vs. 147-149 in O. polyophthalmus) and the existence of a white spot at the center of a semicircle (i.e., no white spot in O. erabo vs. a white spot in O. polyophthalmus). We suggest a new Korean name for O. erabo to be "Mul-bang-ul-ba-da-baem-gang-eo".

• Journal of Oral Medicine and Pain
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• 제31권4호
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• pp.337-346
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• 2006

이 논문은 2년 동안 경북대학병원 구강내과를 턱관절 질환을 주소로 내원한 환자 중에 과두흡수가 있는 환자들로서 자기공명영상, 파노라마, 측방횡두개상 그리고 측방 두부방사선 사진들을 모두 촬영한 34명의 환자들만 선택하여, 측방두부방사선 계측으로 과두흡수와 안면부 골격형태의 연관성을 한국인 정상 교합자들의 평균치와 비교 조사하였고, 전치부 개교합이 동반된 군과 개교합이 없는 군을 서로 비교하였으며, 또한 자기공명영상으로 과두흡수와 관절원판변위와의 관련성을 조사한 결과 과두흡수가 잘 발생될 수 있는 환자들은 다음과 같은 특징을 가졌다: (1) 34명중 1명만이 남자로 여자가 대부분이었다, (2) 연령대는 어느 연령에서나 발생가능하나 10대와 20대에서 발병률이 높았다, (3) 환자들은 높은 하악하연각과 높은 하악각을 가졌다. (4) 하악지의 높이는 작게 나타났으며, (5) 전악각 함요(antegonial notch)가 대체적으로 저명하였다, (6) 구치부 교합은 Angle's Class I 관계가 많았으나, ANB각도는 평균 5.54도로 하악의 후퇴를 나타내었다. (7) 과두흡수는 하악하연각이 낮은 경우에는 거의 발생하지 않았다, (8) 통계학적 유의한 차이는 없었으나 개교합이 동반된 군이 개교합이 없는 군보다 hyperdivergent한 골격형태를 가졌다, (9) 자기공명영상사진에서 과두흡수는 대부분 비정복성 관절원판전위와 연관되어 있었다. 수직적 골격성장이 큰 경우 관절원판 전방변위와 과두흡수의 원인이 될 수 있으리라 생각된다.