• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.106-106
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• 2017

The soybean [Glycine max (L.) Merr.] is one of the most important crop resources worldwide as food and forage. It is also important and valuable that to hold crop resources to have high genetic diversities. Recently, a core collection has been constructed in many plants to preserve the genetic resources of various plants. A core collection is small population to represent the genetic diversity of the total collection, and is of strategic importance as they allow the use of a small part of a germplasm collection that is representative of the total collection. Here, we developed the core collection consisting of 816 accessions by using approximately 180,000 (180K) single nucleotide polymorphisms (SNPs) developed in previous study. In addition, we performed genetic diversity and population structure analysis to construct the core collection from entire 4,392 collections. there were excluded sample call rates less than 93% and duplicated samples more than 99.9% according to genotype analysis using 180K SNPs from entire collections. Furthermore, we were also excluded natural hybrid resources which Glycine max and Glycine soja are mixed in half through population structure analysis. As a result, we are constructed the core collection of genetic diversity that reflects 99% of the entire collections, including 430 cultivated soybeans (Glycine max) and 386 wild soybeans (Glycine soja). The core collection developed in this study should be to provide useful materials for both soybean breeding programs and genome-wide association studies.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.143.1-143.1
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• 2002

• 한국화재소방학회논문지
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• 제34권4호
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• pp.125-134
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• 2020

본 연구는 선행연구에서 다뤄지지 않았던 예방소방과 대비소방을 수방수요에 포함시켜 소방예산에 미치는 영향을 실증적으로 분석하고자 수행되었다. 이를 위해 16개 광역자치단체에서 수행된 예방소방행정(건축허가동의, 특정 소방대상물, 다중이용업, 소방특별조사), 대비소방행정(소방교육 및 훈련), 대응소방행정(화재진압출동, 구급출동) 그리고 소방예산에 대한 11년(2008년-2018년)의 패널자료를 이용하여 실증분석을 실시하였다. 분석결과, 예비소방행정의 소방특별조사, 대비소방행정의 소방교육 및 훈련, 그리고 대응소방행정의 화재진압출동은 소방예산에 유의미한 음(-)의 효과가 있는 것으로 나타났다. 한편, 대응소방행정의 구급출동은 0.01%수준에서 소방예산에 유의미한 양(+)의 효과를 미치는 것으로 나타났다. 이는 우리나라 소방행정의 패러다임이 재난수용(복구중심)에서 재난대응(현장대응중심)을 지나 재난대비(대비중심)로 변화되고 있다는 공공정책을 지지하는 연구결과이다.

• 생약학회지
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• 제31권2호
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• pp.216-223
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• 2000

The anti-inflammatory activity of SEO-KYONG-TANG extract(SKTWE) was examined by using carrageenin- and acetic acid-induced edema, croton oil-induced granuloma pouch, and adjuvant arthritis in rats. In addition, the acute toxicity, analgesic and antipyretic effects of SKTWE were investigated by using general experimental methods in mice. SKTWE did not show acute toxicity at 2400 mg/kg(p.o.) nor 1200 mg/kg(i.p.). After oral administration of the SKTWE to rats, significant anti-inflammatory activity was observed on 1% carrageenin- and 5% acetic acid-induced edema. Also, it significantly inhibited granuloma and exudation in these. In the adjuvant arthritis experiment, the SKTWE decreased the hind paw edema after 3 days of oral administration. In addition, it inhibited the writhing syndromes induced by 0.7% acetic acid in mice. The antipyretic activity of SKTWE was also observed through the typhoid vaccine experiment. These results suggest that SKTWE has analgesic, anti-inflammatory and antipyretic action.

• Journal of Microbiology and Biotechnology
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• 제27권2호
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• pp.412-415
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• 2017

Prebiotics improve the growth or activities of specific microbial genera and species in the gut microbiota in order to confer health benefits to the host. In this study, we investigated the effect of poly-gamma-glutamate (${\gamma}-PGA$) as a prebiotic on the gut microbiota of mice and the organ distributions of ${\gamma}-PGA$ in mice. Pyrosequencing analysis for 16S rRNA genes of bacteria indicated that oral administration of ${\gamma}-PGA$ increased the abundance of Lactobacillales while reducing the abundance of Clostridiales in murine guts. It is suggested that oral administration of ${\gamma}-PGA$ can be helpful for modulating the gut microbiota as a prebiotic.

• 한국컴퓨터정보학회논문지
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• 제24권6호
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• pp.211-216
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• 2019

Knowledge sharing is safe to say that we have already embarked on knowledge-based global economy where knowledge is a decisive factor in global competition for corporations. So in the age of knowledge-based management, it is how we use knowledge that decides success or failure for corporations and the competitiveness of their countries at large as well. We did this research with the help of those who were working in ICT industry including manufacturing, tourism, and others. In this research, we looked into how project participants, organizational characteristic, and relational characteristic affect knowledge sharing and utilization, and what are the factors that have positive effects on corporate success. And all the factors presented in the research are found to have positive effects on the knowledge sharing and utilization. The factors appeared to have positive effects starting with project at first and then on corporate success at large.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.175-175
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• 2001

This experiment tested whether in utero and lactational exposure to 4-nonylphenol (NP) alters mammary gland differentiation in the female offspring rat. Pregnant Sprague Dawley rats were administered NP (l0, 100 mg/kg), atrazine (l00 mg/kg), pesticide demonstrating antiestrogenic activity in mammary gland development, or vehicle (0.5% methyl cellulose) by oral gavage from gestation day 15-19.(omitted)

• Journal of Plant Biotechnology
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• 제50권
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• pp.70-75
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• 2023

In legumes, soyasaponins, one of triterpenoid saponins, are major components of secondary metabolites with a more diverse array of bioactive chemicals. Although the biosynthetic pathway of soyasaponins has been largely studied in soybean, the study on the soyasaponin contents and biosynthesis-related gene expression in pea (Pisum sativum L.) is poorly understood. Here, we found the accumulation of only soyasaponin Bb component in the sprouts of two Korean domestic pea cultivars (Dachung and Sachul). This pattern was consistent with our observation that increased expression of PsUGT73P2 and PsUGT91H4 genes, but not PsCYP72A69, could be responsible for biosynthesis of only soyasaponin Bb in pea by examining their gene expression. However, gradual accumulation of soyasaponin Bb at developmental stages was not consistent with the expression of PsUGT73P2 and PsUGT91H4, suggesting that the changes of their protein activities may affect the accumulation patterns of soyasaponin Bb. We also revealed that the increased expression levels of PsUGT73P2 and PsUGT91H4 during light to dark transition led to increase of soyasaponin Bb contents. Collectively, our results provided a molecular basis of metabolic engineering for enhancing useful soyasaponin Bb metabolites in Korean domestic pea cultivars.

• Asian Journal of Innovation and Policy
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• 제8권1호
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• pp.58-72
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• 2019

The wave of the 4th Industrial Revolution was announced by Schwab Klaus at the 2016 World Economic Forum in Davos, and prospects and measures with the future society in mind have been put in place. With the launch of the Moon Jae-in administration in May 2017, Korea has shifted all of its interest to Big Data, which is one of the most important features of the 4th Industrial Revolution. In this regard, this study focuses on the role of the public sector, explores related issues, and identifies an agenda for determining the demand for ways to foster Big Data ecosystem, from an objective perspective. Furthermore, this study seeks to establish priorities for key Big Data issues from various areas based on importance and urgency using a Delphi analysis. It also specifies the agenda by which Korea should exert national and social efforts based on these priorities in order to demonstrate the role of the public sector in reinforcing the Big Data ecosystem.

• 품질경영학회지
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• 제31권3호
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• pp.19-36
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• 2003

The manager of manufacturing industry just not to have known what to do related to the law of product liability(PL) that was put into operation in July 1, 2002. The law of PL is a public law about defective product, which was established in order to compensate consumer's damages of property and body caused by product, to make sound society by the safety products and to take international competitiveness. But the existing civil law has been having clause that compensation to be taken is limited. The law of PL is resolving this limitations and is characterized by the easy relief from damages of defective product. The decision in the case of Green-man has been a precedent since the court sentenced the manufacturer to liability. The law of PL has been in force in 27 countries, including all of the EU countries, Japan, Philippines and China. It has been shown that the corporations which meet the Global Standard, could survive in global competition. The economic effects by the law of PL are the increase of consumers relief production cost by the lawsuits. This paper will recommend more biref method that is able to cover PSMS by use of QMS. It will make domestic corporation improve in the plan, manufacture and sale of products to meet the Global Standard.