• Title/Summary/Keyword: Mononuclear

Search Result 559, Processing Time 0.025 seconds

Carcinogenicity Evaluation of Diisodecyl Phthalate (DIDP), a Plasticizer, in Rats

  • Cho, Wan-Seob;Han, Beom-Seok;Nam, Ki-Taek;Park, Ki-Dae;Jang, Dong-Deuk;Yang, Ki-Hwa
    • Proceedings of the Korean Society of Toxicology Conference
    • /
    • 2003.05a
    • /
    • pp.105-106
    • /
    • 2003
  • Diisodecyl phthalate (DIDP) which has high physical flexibility, various colors, low viscosity, high stability is used as coating material in ballon, vinyl ink, tent, textile, home and cars interior design and electric cable. In rodents, DIDP is suspected to be a peroxisome proliferator, a nongenotoxic carcinogen. In this study, we performed the carcinogenicity test of DIDP. (omitted)

  • PDF

An outbreak of Riemerella anatipestifer infection in mallard ducks (청둥오리에서 Riemerella anatipestifer 감염 증례)

  • 이성효;임채웅;서석열;도홍기;노수일;이호일;임병무
    • Korean Journal of Veterinary Service
    • /
    • v.22 no.3
    • /
    • pp.257-262
    • /
    • 1999
  • Riemerella anatipestifer (RA) infection is a contagious disease of domestic ducks, turkey, and various other birds. In a flock of mallard ducklings, about 30% of the birds, 3 weeks old, showed lethergy, greenish diarrhea, tremor of head and neck, and died 2-3 days after signs appeared. Grossly, fibrinous exudates covered the heart and surface of the live. Microscopically, mononuclear cells and heterophils were primarily inflammatory cells in the exudate. These were also observed in the meninges in brain. Microbiologically, gram (-) short rod bipolar shaped bacteria were recovered on blood agar and agglutinated by antisera of R anatipestifer. Sulfamethoxasole/trimethoprim were administered and clinically effective. This case was a R anatipestifer infection caused fibrinous pericarditis, hepatitis and meningitis in mallards.

  • PDF

Acute Megakaryoblastic Leukemia (급성 거핵아구성 백혈병 1례)

  • Kim, Young-Jin;Kim, Tae-Nyun;Hyun, Myung-Soo;Shim, Bong-Sup;Lee, Hyun-Woo;Kim, Jung-Suk
    • Journal of Yeungnam Medical Science
    • /
    • v.8 no.2
    • /
    • pp.209-216
    • /
    • 1991
  • Acute Megakaryoblastic leukemia is a rare and rapidly fatal disease characterized by proliferation of megakaryocyte series and atypical megakaryocytes in the bone marrow. Acute Megakaryoblastic leukemia is suspicious when 1) megakaryocyte in peripheral blood, mixture of large and small mononuclear megakaryoblast in the bone marrow 2) cytoplasmic budding in blast 3) myelofibrosis (dense medullary overgrowth of reticulin fibers) 4) PAS(+), ANAE(+), SBB(-), peroxidase(-) and which is confirmed by platelet peroxidase oxidation on electromicroscope or monoclonal antibody. A case of aute megakaryoblastic leukemia was studied morphologically and monoclonal antibody.

  • PDF

Clinical utilization of cord blood over human health: experience of stem cell transplantation and cell therapy using cord blood in Korea

  • Lee, Young-Ho
    • Clinical and Experimental Pediatrics
    • /
    • v.57 no.3
    • /
    • pp.110-116
    • /
    • 2014
  • Cord blood (CB) has been used as an important and ethical source for hematopoietic stem cell transplantation (SCT) as well as cell therapy by manufacturing mesenchymal stem cell, induced pleuripotential stem cell or just isolating mononuclear cell from CB. Recently, the application of cell-based therapy using CB has expanded its clinical utility, particularly, by using autologous CB in children with refractory diseases. For these purposes, CB has been stored worldwide since mid-1990. In this review, I would like to briefly present the historical development of clinical uses of CB in the fields of SCT and cell therapy, particularly to review the experiences in Korea. Furthermore, I would touch the recent banking status of CB.

A Study on the Tungsten (VI) Complexes with the Organic Acid Anhydrides (유기산 무수물을 리간드로한 텅스텐 (VI) 착물에 관한 연구)

  • Sang-Oh Oh;Kim, Chan Ho
    • Journal of the Korean Chemical Society
    • /
    • v.19 no.6
    • /
    • pp.408-413
    • /
    • 1975
  • Dichloro-dioxo-tungsten(VI) complexes containing oxygen donor in anhydrous organic acid have been synthesized. Sodium tungstate reacts with acetylchlorides to produce the mononuclear complexes, yellow powder having $WO_2Cl_2(RCO)_2O$ as general formula. Their chemical properties and the possible structure are proposed by the results of spectral data and chemical observation.

  • PDF

A STUDY OF THE MALIGNANT FIBROUS HISTIOCYTOMA (악성 섬유성 조직구종에 관한 연구)

  • Kim Young-Jin;Oh Phill-Gyo;Choi Eui-Hwan
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
    • /
    • v.24 no.2
    • /
    • pp.451-457
    • /
    • 1994
  • Malignant fibrous histiocytoma(MFH) is relatively rare in the oro-maxillofacial region, particularly in the oral cavity. MFH usually arise in the extremities, the thigh being the most common site. The incidence of malignant fibrous histiocytoma in bones is rather low compared with that in soft tissues. MFH is predominant in the 40s and 50s. Histologically, the lesion are said to show high cellularity with fibrous stroma, cellular and nuclear pleomorphism, an admixture of fibroblast-like spindle cells which tend to be arranged in whorls or cartwheel or storiform patterns, rounded mononuclear cells and multinucleated giant cells. The cells frequently have abundant eosinophilic cytoplasm which has a foamy or vesicular appearance. Treatment consists of varying combinations of radiation therapy, chemotherapy, and surgery. We have observed a case of malignant fibrous histiocytoma occured in the right maxilla of 32-year-old woman.

  • PDF

Degenerative joint disease with systemic mycoses in a oriental white stork

  • Lee, Sook-Jin;Han, Je-Ik;Chang, Dong-Woo;Na, Ki-Jeong
    • Korean Journal of Veterinary Research
    • /
    • v.47 no.1
    • /
    • pp.95-98
    • /
    • 2007
  • Rehabilitation Research was presented to Veterinary Medical Center of Chungbuk National Universitywith anorexia and lameness for 5 days. Bilateral intertarsal joint swellings were observed in physicalexamination. The radiographic findings indicated degenerative changes of joint cartilage and suroundingbones. In cytologic examination of synovial fluids, mononuclear leukocytic inflammation was identified.on Sabroud dextrose agar. From all of examinations, this patient was diagnosed as a degenerative jointdisease with systemic mycoses.

Outbreak of Leucocytozoonosis in Chickens (닭 Leucocytozoon병(病)의 집단발생(集團發生)과 병리학적(病理學的) 관찰(觀察))

  • Kwak, Soo-Dong;Jyeong, Jong-Sik
    • Korean Journal of Veterinary Research
    • /
    • v.23 no.2
    • /
    • pp.183-186
    • /
    • 1983
  • The clinical and histopathological observation of leucocytozoonosis was carried out during July, 1982 at a poultry compound in Gyeongbuk province and the results were summarized as follows: 1. Leucocytozoonosis was observed in 36,900 of 59,900 chickens (61.6%) and the mortality rate was 18.3% (6,760 of 36,900 chickens infected). 2. Clinical findings were anorexia, dyspnea, paleness of comb, greenish diarrhea and reduction of egg production. 3. Gross lesions were yellowish white spots scattered on parenchymal organs and swelling of liver and spleen. In addition, petechiation and ecchymosis of small intestine, egg yolk and subcutaneous tissues were observed. 4. Histological findings were infiltration of mononuclear cells in liver, heart and lung, appearance of megaloschizonts in heart, liver, proventriculus and pancreas, proliferation of foreign body giant cells in heart, and hyperemia and swelling of all parenchymal organs.

  • PDF

A New Chemosensing Ensemble for Colorimetric Detection of Oxalate in Water

  • Tang, Li-Jun;Liu, Ming-Hui
    • Bulletin of the Korean Chemical Society
    • /
    • v.31 no.11
    • /
    • pp.3159-3162
    • /
    • 2010
  • To realize highly selective recognition of oxalate in water, a new chemosensing ensemble that behaves highly selective colorimetric recognition of oxalate in water at pH 7.4 has been developed. The ensemble was constructed by a pyrrole containing mononuclear copper complex and chromeazurol S. The ensemble shows a highly selective recognition of oxalate through an obvious color change from blue to yellow upon the addition of oxalate, whereas, other dicarboxylates such as malonate, succinate, fumarate, maleate, glutarate, adipate, phthalate, isophthalate and terephthalate do not induce any noticeable color changes. The oxalate recognition process is not significantly affected by other coexisting dicarboxylate.

A Case of Canine Hydrocephalus with Nonsuppurative Encephalitis (비화농성 뇌염을 동반한 개 수두증 1례)

  • 한정희;서강문
    • Journal of Veterinary Clinics
    • /
    • v.17 no.2
    • /
    • pp.470-474
    • /
    • 2000
  • A Shih Tzu Puppy had clinical onset of anotexia crying and progression of neurological sings when enlargement of the cranial vault at 1 month old and died after showing clinical signs during 2 months period. Radiological and pathological examinations were performed. Radiological findings were homogeneous appearance of the calvaria with cortical thinning, loss of the normal convolutional skull markings and persistent fontanelles. Grossly enlargement of the cranial vault thinning of the bone and defective closure of the fontanelles were also observed. The entire subcortical area of the cerebral hemispheres with severe, dilatation of ventricles and cerebrospinal fluid(CSF) wits absent. There was parenchyma atrophy affecting chiefly in the white mater and the cerebral cortices, axon degeneration and necrosis and gitter cell infiltration in the whiter matter and the subependymal area. Mononuclear perivacular cuffing in the cerebrum and the pons was shown. Based on the radiological, gross and histopathological findings, this case was believed to have congenital hydrocephalus with nonsuppurative encephahitis. Possible etiology on the case is also discussed.

  • PDF