• Macromolecular Research
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• v.11 no.4
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• pp.207-223
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• 2003

For last five years, we are developing the novel local drug delivery devices using biodegradable polymers, especially polylactide (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) due to its relatively good biocompatibility, easily controlled biodegradability, good processability and only FDA approved synthetic degradable polymers. The relationship between various kinds of drug [water soluble small molecule drugs: gentamicin sulfate (GS), fentanyl citrate (FC), BCNU, azidothymidine (AZT), pamidronate (ADP), $1,25(OH)_2$ vitamin $D_3$, water insoluble small molecule drugs: fentanyl, ipriflavone (IP) and nifedipine, and water soluble large peptide molecule drug: nerve growth factor (NGF), and Japanese encephalitis virus (JEV)], different types of geometrical devices [microspheres (MSs), microcapsule, nanoparticle, wafers, pellet, beads, multiple-layered beads, implants, fiber, scaffolds, and films], and pharmacological activity are proposed and discussed for the application of pharmaceutics and tissue engineering. Also, local drug delivery devices proposed in this work are introduced in view of preparation method, drug release behavior, biocompatibility, pharmacological effect, and animal studies. In conclusion, we can control the drug release profiles varying with the preparation, formulation and geometrical parameters. Moreover, any types of drug were successfully applicable to achieve linear sustained release from short period ($1{\sim}3$ days) to long period (over 2 months). It is very important to design a suitable formulation for the wanting period of bioactive molecules loaded in biodegradable polymers for the local delivery of drug. The drug release is affected by many factors such as hydrophilicity of drug, electric charge of drug, drug loading amount, polymer molecular weight, the monomer composition, the size of implants, the applied fabrication techniques, and so on. It is well known that the commercialization of new drug needs a lot of cost of money (average: over 10 million US dollar per one drug) and time (average: above 9 years) whereas the development of DDS and high effective generic drug might be need relatively low investment with a short time period. Also, one core technology of DDS can be applicable to many drugs for the market needs. From these reasons, the DDS research on potent generic drugs might be suitable for less risk and high return.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.560-569
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• 2015

Crowd funding is the method of raising money for a project, companies from a large group of people via the Internet, in return for future products or equity. Kickstarter is the largest and most successful crowdfunding site where creative projects raise reward based funding. Drawing on dataset of 80,267 projects with combined funding over $1.3b from 8.1m people, this paper suggest that backer select project based on their preference on the project, instead profitability of the project. It suggests that well-established platform and big size of network increases the chance of success of the project due to a ripple effect and blockbuster effects. Clear communication about the project's idea and goal is highly correlated with success. Regular communication on the project site, such as by constant progress updates, helps the success of the project. Equity-based crowdfunding is emerging as an innovative means of raising capital for businesses, so it has been receiving a lot of attention and expectation from the government and the market. The findings of this paper and others will help to get some understanding and insight into equity-based crowdfunding. However, Kickstarter differs from equity-based crowdfunding in the goals of the backers. Kickstarter's backers are not investors, they are contributors. To understand equity-based crowdfunding, the subject will need further study.

• Korean Journal of Construction Engineering and Management
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• v.17 no.5
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• pp.35-44
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• 2016

Various risk factors are known to be the nature of construction project execution process. These factors lead to potential claims, dispute mediation, arbitration, and litigation which can result in huge loss of money and time. Therefore, it is necessary for construction companies in Korea to improve overall project management capability through the evaluation before entering into the overseas construction market. Also, after examination of the claim and dispute caused by construction project risks, a substantial degree of influence and active preparation for the claim and dispute management should be confirmed via the effect analysis of the each factors. Main claim causes were derived through claim and dispute cases involved with domestic construction projects. As a prediction result of the main claim, 16.1% of the construction change claim, 5.7% of the bad faith claim and 2.7% for the construction delay claim were found to be the portion of the total construction cost. As a result of this analysis, risk management methodology was suggested to improve a project management capability for domestic construction companies through analysis result of the main factors of construction claims.

• Journal of Korean Society of Forest Science
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• v.99 no.4
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• pp.517-527
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• 2010

The purpose of this study was to investigate the causal relationship among perceived value, satisfaction and revisit intention for visitors of the Korea National Arboretum. Three hundred respondents were selected by quota sampling, and well-known measurement scales utilized in marketing field were adopted in order to measure three variables with some modification to apply for arboretum visitors. Results of structural equation model showed that perceived value affected visitors' satisfaction, which in turn influenced revisit intention. Specifically, "emotional value" had the most significant influence on satisfaction, followed by "value for money" and "novelty value"; however, "social value" was not an influential construct. Based on calibration results, several strategies were suggested for the effective management. Authors advised that (a)improvement of measurement scale of value, (b)inclusion of self-congruity as antecedent variable to satisfaction, (c)changing revisit intention to word-of-mouth communication as a post-purchase behavioral intention, and (d)implementation of market segmentation should be considered for future research.

• Journal of Animal Science and Technology
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• v.47 no.1
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• pp.115-132
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• 2005

This research was conducted to make suggestions for the promotion of research activities in the field of animal resources sciences, and we evaluated the research funding trend and the present status of research funding offered by KOSEF in this field. Comparative portion of the number of research projects and grants in this field to other fields has a tendency to be decreased year by year except recent few years. Researchers in this field have received more research funding from the group-based program than from the individual-based program. Also, they have received less money(per project) than did researchers in the fields of general agricultural sciences and other science and technology. Researchers in this field ranges from 43 to 51 years of age and showed 48 years of average age. It was found that researchers who has been funded in the field of animal resources sciences have showed tendency of publication of more articles to SCI journals in recent 5 years. The strong points of the animal resources of agricultural sciences field in South Korea include: lots of researchers, the establishment of research infra-structure, the excellence in research competitiveness and technology level. However, its weaknesses are: a lack of leadership in relevant societies and institutes, a predicted shortfall of researchers in the next generation and insufficient research productivity. The opportunities include: increasing the importance of the biotechnology industry, activating international cooperation researches and exploring the multitude of possible research areas to be studied. However, some concerns still exist, such as threats from developed countries for the government to open the agricultural market, the reduction of the number of full-time farms and intensification of needs for economic and social effects. The diverse actions and systems based upon the strongpoint, weakness, opportunity and threats above-mentioned are required to encourage research activities in the field of animal resources of agricultural sciences in Korea In addition, researchers in this fields would make an effort to keep pace with international society as well as domestic demands.

• Journal of Korea Entertainment Industry Association
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• v.14 no.3
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• pp.173-180
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• 2020

According to KISA, many people play smartphone games. stress relieving, time is the reason to beat. Attempts to combine mobile games and education in the Korean game market are continuing. Studies have shown that using commercial games for education can be effective. Also, researches for activation educational games are increasing. Creating educational games requires a lot of time and money. Due to the nature of mobile games, the service is often terminated without updating. If you are able to acquire a naturally educational part while playing mobile games, you will see the effect of one pair of fun and education, both at once. We analyzed the education factors of the game with 'Real Farm' which is a simulation farm game. We focused on analyzing information acquisition and utilization part through indirect experience which is characteristic of simulation and examined educational factors based on design elements of educational game. This can signal the positive aspects of the game and the educational content of existing games. If you use smartphones as a pedagogy, you can expect a positive perception of games and an increase in the average life expectancy of mobile games.

• Journal of Korean Port Research
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• v.6 no.1
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• pp.93-110
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• 1992

The most change in this century is supposed to be declination of ideology, and block of world economy. Addition to down full of cold war atmosphere around Northeast Asia, not only economic and social mood in this region is dramatically changed, but also it gave birth to the block of Northeast economy that accerlated new hub of world economy. According to dramatic change of economic surroundings the dynamic potential of growth in this region will be guided to enlarge inter-regional trade and increase volume of trade, thus suggests to grow steadily transportation. cargos in this region will have to arrange the system of delivery and inner transportation, accessary facilities, inter-regional harbors if North America and EC has connected easily. As have accerlated GATT and UR represented multilateralism and regionalism, it has regulated to increase trades of region due to relief of the trade barrier through specific areas has agreed with separately. The flow of regionalism of world economy has appeared to realize EC and NAFTA centered U.S.A, and also has presented to free trade region or one-size market agreement in Asia as APEC, EAEG in Malaysia, and etc. In defense to this block and internationalism of world economy, Pusan has to come forward to the hub of Northeast others has proposed a project to dominate the Northeast, Economy Association Agreement as Far East comprehensive development project in USSR, Hunchun development project in NK, and East Sea development project in PRC, Niigate regional development in Japan, Duman River development project in NK, and East Sea development project in Korea. As this exercise has proceed, Pusan also have arranged development strategy definitely and prepared provisions systematically. Engaging to participate center of delivery system is meant to be completed complex functions, namely the transfer storage processing & assembly function of international commodity. Pusan has ability to be terminal point of TSR. it had been connected to EC as the biggest economy block and TKR as complex transportation root to Far East, it would be the center of inground and seabase delivery terminal to Rotterdom as the biggest container pier and major piers to North-East and South East Asia. In order to provide a Role of 21 century's internationalization, Pusan has appealed to participate in management information research and development connected to Pohang-Ulsan-Changwon-Masan, and has utilized efficiently the resources such as man, material, money and information.

• Industry Promotion Research
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• v.8 no.2
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• pp.21-27
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• 2023

This study studies the policies and use cases of the government and the financial sector for artificial intelligence, and the future policy tasks of the financial sector. want to derive According to Gartner, noteworthy technologies leading the financial industry in 2022 include 'generative AI', 'autonomous system', 'Privacy Enhanced Computation (PEC) was selected. The financial sector is developing new technologies such as artificial intelligence, big data, and blockchain. Developments are spurring innovation in the financial sector. Data loss due to the spread of telecommuting after the corona pandemic As interests in sharing and personal information protection increase, companies are expected to change in new digital technologies. Global financial companies also utilize new digital technology to develop products or manage and operate existing businesses. I n order to promote process innovation, I T expenses are being expanded. The financial sector utilizes new digital technology to prevent money laundering, improve work efficiency, and strengthen personal information protection. are applying In the era of Big Blur, where the boundaries between industries are disappearing, the competitive edge in the challenge of new entrants In order to preoccupy the market, financial institutions must actively utilize new technologies in their work.

• Journal of Navigation and Port Research
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• v.46 no.6
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• pp.483-490
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• 2022

Floating LiDAR is a system that provides a new paradigm for wind condition observation, which is essential when creating an offshore wind farm. As it can save time and money, minimize environmental impact, and even reduce backlash from local communities, it is emerging as the industry standard. However, the design and verification of a stable platform is very important, as disturbance factors caused by fluctuations of the buoy affect the reliability of observation data. In Korea, due to the nation's late entry into the technology, a number of foreign equipment manufacturers are dominating the domestic market. The west coast of Korea is a shallow sea environment with a very large tidal difference, so strong currents repeatedly appear depending on the region, and waves of strong energy that differ by season are formed. This paper conducted a study examining buoys suitable for LiDAR operation in the waters of Korea, which have such complex environmental characteristics. In this paper, we will introduce examples of optimized design and verification of ship-type buoys, which were applied first, and derive important concepts that will serve as the basis for the development of various platforms in the future.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.2
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• pp.245-256
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• 2024

Since 2020, quantitative easing and easy money policies have been implemented for the purpose of economic stimulus. As a result, real estate prices have skyrocketed. In this study, the relationship between sales and rental prices by housing type during the period of soaring real estate prices in Busan was analyzed spatio-temporally. Based on the actual transaction price data, housing type, transaction type, and monthly data of district units were constructed. Among the spatio-temporal analysis models, the SpVAR, which is used to understand the temporal and spatial effects of variables, and the GSTAR, which is used to understand the effects of each region on those variables, were used. As a result, the sales price of apartment had positive effect on the sale price of apartment, row house, and detached house in the surrounding area, including the target area. On the other hand, it was confirmed that demand was converted to apartment rental due to an increase in apartment sales prices, and the sale price fell again over time. The spatio-temporal spillover effect of apartments was positive, but the positive effect of row house and detached house were concentrated in the original downtown area.