• 한국재료학회지
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• 제14권2호
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• pp.157-162
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• 2004

The object of this research is to develop a carbon molecular sieve(below CMS) which can separate selectively to convert mixture gases spout at waste landfill into fuel. And this research is meaningful from the viewpoint of a quality improvement of CH$_4$ gas and an utilization of by-product. CMS was prepared using coconut shell powder as starting material and the effects of activators, temperature and modifier on the reaction were investigated in this research. Also, pore diameter, surface area of CMS and adsorption rate were measured and studied by cahn balance and ASAP2010. Its specific surface area and pore distribution were controlled easily at 800^{\circ}C and adsorption rate was very good. The CMS prepared in this research is shown to be able to separate landfill gases very effectively.

• 한국수소및신에너지학회논문집
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• 제27권5호
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• pp.612-619
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• 2016

Pitch synthesis reaction was studied based on the effect for chemical composition of feedstock. Feedstock was selected as pyrolyzed fuel oil (PFO) and coal-tar (CT), which are by-products in petroleum and steel industry. Pitch was prepared at $420^{\circ}C$ for 180 minutes on atmospheric pressure by thermal treatment. Thermal stability and softening point (SP) of the prepared pitches were investigated and their molecular weight distribution was analyzed by MALDI-TOF. PFO has various aliphatic compounds and coal-tar has high aromaticity with 3 wt% of primary quinoline insolubles. The thermal property of PFO was enhanced with polymerization reaction during the thermal treatment with increased molecular weight range. But CT was inferior to PFO because of side reaction by hetero elements. CTP was appeared molecular weight by 0~200 m/z.

• Journal of Microbiology and Biotechnology
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• 제18권5호
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• pp.968-974
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• 2008

Proteomic analysis led to identification of the proteins of Vibrio vulnificus that were induced upon exposure to INT-407 cells, and 7 of which belong to the functional categories such as amino acid transport/metabolism, nucleotide transport/metabolism, posttranslational modification/protein turnover/chaperones, and translation. Among the genes encoding the host-induced proteins, disruption of purH, trpD, tsaA, and groEL2 resulted in reduced cytotoxicity. The purH, trpD, and tsuA mutants showed impaired growth in the INT-407 lysate; however, the growth rate of the groEL2 mutant was not significantly changed, indicating that the possible roles of the host-induced proteins in the virulence of V. vulnificus are rather versatile.

• Bulletin of the Korean Chemical Society
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• 제13권1호
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• pp.26-29
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• 1992

Copolymers with two different side groups, 2,2,2-trifluoroethoxy and p-chlorophenoxy groups, have been synthesized by reaction of poly(dichlorophosphazene) with their sodium salts, and characterized by elemental analysis, gel permeation chromatography, IR and NMR spectroscopies. The molecular weight measurement has shown that the weight average molecular weight, ${\bar{M}}_w$ of the copolymers are all above $10^6$ and their molecular weight distributions are monomodal and narrow (${\bar{M}}_w/{\bar{M}}_n<4$). Thermal properties of these copolymers measured by DSC and TGA exhibited to be intermediate between those of the two corresponding homopolymers.

• Genomics & Informatics
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• 제17권1호
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• pp.3.1-3.4
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• 2019

Intratumor heterogeneity within a single tumor mass is one of the hallmarks of malignancy and has been reported in various tumor types. The molecular characterization of intratumor heterogeneity in breast cancer is a significant challenge for effective treatment. Using single-cell RNA sequencing (RNA-seq) data from a public resource, an ERBB pathway activated triple-negative cell population was identified. The differential expression of three subtyping marker genes (ERBB2, ESR1, and PGR) was not changed in the bulk RNA-seq data, but the single-cell transcriptomes showed intratumor heterogeneity. This result shows that ERBB signaling is activated using an indirect route and that the molecular subtype is changed on a single-cell level. Our data propose a different view on breast cancer subtypes, clarifying much confusion in this field and contributing to precision medicine.

• BMB Reports
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• 제52권1호
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• pp.42-46
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• 2019

Cellular senescence, a process of cell proliferation arrest in response to various stressors, has been considered to be important factor in age-related disease. Identification of senescent cells in tissues is limited and the role of senescent cells is poorly understood. Recently however, several studies showed the characterization of senescent cells in various pathologic conditions and the role of senescent cells in disease progression is becoming important. Senescent cells are growth-arrested cells, however, the senescence associated secretory phenotype (SASP) of senescent cells could modify the tissues' microenvironment. Here, we discuss the progress and understanding of the role of senescent cells in tissues of pathologic conditions and discuss the development of new therapeutic paradigms, such as senescent cells-targeted therapy.

• Mycobiology
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• 제49권2호
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• pp.183-187
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• 2021

The Shine Muscat is a table grape, popular in South Korea for its unique mango-flavor taste. Flyspeck is a disease that is characterized by small, black, and circular specks on the grape cuticle was first observed in several commercial orchards in Sangju, South Korea, in August 2019. Here we identified the causal agent of flyspeck based on an advanced diagnosis approach, comprised of both morphological and molecular analyses. Morphological characteristics of the cultures isolated from grape flyspeck were identical to the fungus Cladosporium perangustum. The concatenated sequences of ITS, ACT, and EF1-α were used for molecular phylogenetic analysis, BLAST searches along with Bayesian inference-based phylogeny, confirmed that the causal agent of grape flyspeck is C. perangustum. The cultured fungal isolates also produced flyspeck symptoms on healthy fruits in pathogenicity tests. To the best of my knowledge, this is the first documented evidence of any Cladosporium sp. producing flyspeck symptoms on any plant.

• Bulletin of the Korean Chemical Society
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• 제20권3호
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• pp.333-336
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• 1999

The polyaniline films with various insoluble parts are fabricated. The oxidation state (1-y) of these polyaniline is 0.53 and 0.54, respectively. To control the interchain and intrachain interaction of the polymer, the polyaniline films are stretched with appropriate ratio. The insoluble part of polyaniline synthesized at room temperature (low molecular weight) is 12%-76% and that of polyaniline synthesized at 0 'IC (intermediate molecular weight) is 65%-89%. The low molecular weight polyaniline films with various drawing ratios have amorphous structure. In the intermediate weight polyaniline films, the crystallinity of films increases with drawing ratio as well as insoluble part. The difference of the insoluble part affects electrical conductivity which is increased dramatically with draw ratio. In particular, the higher insoluble part caused greater increase in electrical conductivity.

• Mycobiology
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• 제50권2호
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• pp.150-154
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• 2022

Rhytisma lonicericola was identified as a tar spot fungus on Lonicera sp. in 1902, and has since been recorded on several species of Lonicera in China, Japan, and Korea. Most of the previous records of R. lonicericola have been based on a list of disease occurrences in the absence of any formal morphological identification or molecular analyses. Using six newly obtained specimens collected in the past 2 years, we confirmed the tar spot fungus found on L. japonica in Korea as R. lonicericola based on morphological examinations and molecular phylogenetic analyses. This fungus was distinguished from R. xylostei, another tar spot fungus on Lonicera, by ascospore size and geographical distributions. We present detailed mycological information and, for the first time, DNA sequence data useful for the identification of R. lonicericola.

• 대한방사성의약품학회지
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• 제8권1호
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• pp.25-32
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• 2022

Malignant melanoma has an aggressive nature and high metastatic potential that result in one of the highest cancer mortality rates. Over the past three decades, primary and metastatic melanoma incidence has rapidly increased. The recent advances in diagnostic technology have shown promise, but there is still an enormous need for specific detection methods to diagnose malignant melanoma. Positron emission tomography can visualize a particular biomarker of malignant melanoma and promise a noninvasive image of micrometastases. However, the development of PET radiopharmaceuticals remains necessary for diagnosing malignant melanoma by using positron emission tomography. In this review, the history and a general overview of PET radionuclide labeled benzamide derivatives, including their radiosynthesis, in vivo characterization, and evaluation, are provided as imaging agents for malignant melanoma.