• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2008년도 International Meeting of the Microbiological Society of Korea
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• pp.59-61
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• 2008

• 한국동물학회:학술대회논문집
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• 한국동물학회 1997년도 공동 춘계학술대회
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• pp.70.2-70
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• 1997

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• IEIE Transactions on Smart Processing and Computing
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• 제5권1호
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• pp.5-9
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• 2016

The modulation bandwidth of a reflective semiconductor optical amplifier (RSOA) is limited by carrier lifetime. Therefore, it is hard to directly modulate an RSOA with high-speed electrical signals. We theorize that an optical filter can act as an optical equalizer, compensating for the narrow bandwidth limitation imposed by the RSOA. By modeling a time-varying RSOA with a modified transfer matrix method (TMM), we simulated 25 Gbps operation of an RSOA with optical filtering effects. We investigated the impact of detuning the center wavelength of the optical filter on the modulation of an RSOA. The numerical results show that it is possible to modulate an RSOA with an optical filtering effect at 25 Gbps without electronic equalization or digital signal processing.

• Journal of Power Electronics
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• 제14권6호
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• pp.1263-1271
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• 2014

A novel hysteresis PWM control strategy for synchronous buck converter is proposed. The proposed control strategy is based on ampere-second balance of the modulate capacitor, which not only offers faster transient response to meet the challenges of the power supply requirements of fast dynamic load changes, but also provides better stability and solves the compensation problem of error amplifier in the conversional voltage PWM control. Finally, the steady-state and dynamic operation of the control method is analyzed and verified by simulation and experimental results.

• 한국광학회지
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• 제3권4호
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• pp.217-221
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• 1992

광통신에 각종 modulator를 사용할 경우에 대비하여 plano-convex coupling 미세광학소자를 설계하였다. 광섬유에서 회절되는 광을 시준시켜 modulate할 수 있도록 하는 시준렌즈와 modulate된 광을 광섬유에 연결시키는 coupling렌즈를 설계하였다. 광원은 He-Ne 레이저 빔으로하고 렌즈의 초자는 BK-7 크라우ㅌ계 광학유리로 하였다. 곡률반경과, 거리 및 conic costant가 광학계의 광선수차에 미치는 영향을 조사하였다.

• 한국통신학회논문지
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• 제21권10호
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• pp.2670-2678
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• 1996

Reticle seekers temporally modulate target location onto the incoming spatial signal. When large or multiple targets are present in the FOV, however, it is hard to precisely modulate the incoming target signal by the relicle. To solve this loss of modulatoin depth problem, we present an improved retical seeker using the segmented focal plane array(FPA). The new reticle system uses the normalized difference as well as the modulated signal of each detector output in the segmented FPA. In simulation, we have ascertained the proposed system can make an effective analysis and tracking for multiple or large targets.

• Current Optics and Photonics
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• 제3권1호
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• pp.1-7
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• 2019

Optical stimulation provides a promising alternative to electrical stimulation to selectively modulate tissue. However, developing noninvasive techniques to directly stimulate excitable tissue without introducing genetic modifications and minimizing cellular stress remains an ongoing challenge. Infrared (IR) light has been used to achieve optical pacing for electrophysiological studies in embryonic quail and mammalian hearts. Here, we demonstrate optical stimulation and pacing of the embryonic chicken heart using a pulsed infrared thulium laser with a wavelength of 1927 nm. By recording stereomicroscope outputs and quantifying heart rates and movements through video processing, we found that heart rate increases instantly following irradiation with a large spot size and high radiant exposure. Targeting the atrium using a smaller spot size and lower radiant exposure achieved pacing, as the heart rate synchronized with the laser to 2 Hz. This study demonstrates the viability of using the 1927 nm thulium laser for cardiac stimulation and optical pacing, expanding the optical parameters and IR lasers that can be used to modulate cardiac dynamics.

• Molecules and Cells
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• 제44권7호
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• pp.529-537
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• 2021

Most animals face frequent periods of starvation throughout their entire life and thus need to appropriately adjust their behavior and metabolism during starvation for their survival. Such adaptive responses are regulated by a complex set of systemic signals, including hormones and neuropeptides. While much progress has been made in identifying pathways that regulate nutrient-excessive states, it is still incompletely understood how animals systemically signal their nutrient-deficient states. Here, we showed that the FMRFamide neuropeptide FLP-20 modulates a systemic starvation response in Caenorhabditis elegans. We found that mutation of flp-20 rescued the starvation hypersensitivity of the G protein β-subunit gpb-2 mutants by suppressing excessive autophagy. FLP-20 acted in AIB neurons, where the metabotropic glutamate receptor MGL-2 also functions to modulate a systemic starvation response. Furthermore, FLP-20 modulated starvation-induced fat degradation in a manner dependent on the receptor-type guanylate cyclase GCY-28. Collectively, our results reveal a circuit that senses and signals nutrient-deficient states to modulate a systemic starvation response in multicellular organisms.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2007년도 춘계 학술대회
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• pp.18-18
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• 2007

• Journal of Periodontal and Implant Science
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• 제48권2호
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• pp.70-83
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• 2018

Purpose: The aim of this study was to evaluate the capacity of single and combined applications of the bark of the stems and roots of Magnolia officinalis Rehd. et Wils. (Magnoliae Cortex) and Zea mays L. (maize) to modulate inflammation in RAW 264.7 cells stimulated with Porphyromonas gingivalis. Methods: RAW 264.7 cells were stimulated with P. gingivalis, and Magnoliae Cortex and/or maize was added. Cytotoxicity and the capacity to modulate inflammation were determined with a methylthiazol tetrazolium (MTT) assay, nitrite production, enzyme-linked immunosorbent assay (ELISA), and western blotting. Results: Treatment with Magnoliae Cortex and/or maize inhibited nuclear transcription factor ${\kappa}B$ ($NF-{\kappa}B$) pathway activation and nuclear p44/42 mitogen-activated protein kinase (MAPK) and inducible nitric oxide synthase (iNOS) protein expression in P. gingivalis-stimulated RAW 264.7 cells. Moreover, the treatments suppressed cytokines (prostaglandin $E_2$ [$PGE_2$], interleukin $[IL]-1{\beta}$, and IL-6) and nitrite production. Conclusions: Both Magnoliae Cortex and maize exerted an anti-inflammatory effect on P. gingivalis-stimulated RAW 264.7 cells, and this effect was more pronounced when the extracts were combined. These findings show that these extracts may be beneficial for slowing the progression of periodontal disease.