• Genomics & Informatics
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• v.18 no.4
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• pp.38.1-38.9
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• 2020

Chronotype is an important moderator of psychiatric illnesses, which seems to be controlled in some part by genetic factors. Clock genes are the most relevant genes for chronotype. In addition to the roles of individual genes, gene-gene interactions of clock genes substantially contribute to chronotype. We investigated genetic associations and gene-gene interactions of the clock genes BHLHB2, CLOCK, CSNK1E, NR1D1, PER1, PER2, PER3, and TIMELESS for chronotype in 1,293 healthy Korean individuals. Regression analysis was conducted to find associations between single nucleotide polymorphism (SNP) and chronotype. For gene-gene interaction analyses, the quantitative multifactor dimensionality reduction (QMDR) method, a nonparametric model-free method for quantitative phenotypes, were performed. No individual SNP or haplotype showed a significant association with chronotype by both regression analysis and single-locus model of QMDR. QMDR analysis identified NR1D1 rs2314339 and TIMELESS rs4630333 as the best SNP pairs among two-locus interaction models associated with chronotype (cross-validation consistency [CVC] = 8/10, p = 0.041). For the three-locus interaction model, the SNP combination of NR1D1 rs2314339, TIMELESS rs4630333, and PER3 rs228669 showed the best results (CVC = 4/10, p < 0.001). However, because the mean differences between genotype combinations were minor, the clinical roles of clock gene interactions are unlikely to be critical.

• Journal of Digital Convergence
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• v.13 no.12
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• pp.117-124
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• 2015

As the acceptance of statistical analysis has been increased because of Big Data, the needs for an advanced second generation of statistical analysis method like Structural Equation Model are also increasing. This study suggests how R-Program, as open software, can be utilized when Partial Least Square Model, one of the SEMs, is applied to statistical analysis. R is a free software as a part of GNU projects as well as a powerful and useful tool for statistical analysis including Big Data. The study utilized R and SmartPLS, a representative statistical package of PLS-SEM, and analyzed internal consistency reliability, convergent validity, and discriminant validity of the measurement model. The study also analyzed path coefficients and moderator effects of the structural model and compared the results, respectively. The results indicated that R showed the same results with SmartPLS on the measurement model and the structural model. Therefore, the study confirmed that R could be a powerful tool that is alternative to a commercial statistical package in the future.

• Research in Community and Public Health Nursing
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• v.29 no.3
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• pp.359-370
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• 2018

Purpose: The purpose of this study is to identify effects of the variables of Health Action Process Approach (HAPA) Model on physical activity. Methods: This study has conducted a systematic literature review and meta-analysis. Sixteen articles were searched through electronic databases (PsycINFO, PubMed, CINAHL, Web of science, Science Direct, RISS, KMBASE, KoreaMed, KISS, DBpia) and additional journals from 2000 to July, 2017. To estimate the effect size (ES), the meta-analysis of the studies was performed by using Comprehensive Meta-Analysis programs. Results: The overall effect size of the variables of HAPA on physical activity was median (ES=.28). Of the core variables of HAPA model, action control (ES=.43) showed the largest effect size, followed by coping self-efficacy (ES=.31) and planning (ES=.31).Additional variables were identified as preparatory behavior (ES=.39) and past physical activity (ES=.24). Through the moderator effect analysis, the effect size was higher in the volitional phase than in the motivational phase, and higher in the healthy group than in the patient group. The higher the proportion of males and the lower the age, the larger the effect size. Conclusion: This finding shows empirical evidence that all core variables of the HAPA model are useful for predicting physical activity. We propose the use of the HAPA model to develop physical activity promotion intervention.

• Korean Journal of Artificial Intelligence
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• v.7 no.1
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• pp.5-12
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• 2019

The study is to identify the factors influencing Chinese consumers' intentions to purchase organic food based on Theory of Planned Behavior (TPB) model. This research concentrates on the moderating effect of gender during the process. An offline investigation was used for the research purpose. Data for the study was gathered from February to March 2018. The total of 260 valid responses was used for this analysis. An online questionnaire was distributed through Email to Chinese consumers living in major cities of China and abroad to collect the data. Multi group analysis and model comparison were conducted to examine the moderating effect of gender. Our results support previous researches suggesting that gender moderates the relationship between attitude and behavioral intention. However, surprisingly, no significant moderating effect of gender on the relationship between subjective norms and behavioral intention was found. This paper revisited TPB antecedents and the moderating effect of gender focusing on Chinese organic food markets. The findings provide essential managerial implications to the marketers in this industry. Further research could examine whether TPB model can be applied to other potential purchasing groups.

• Proceedings of the Korean Society for Quality Management Conference
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• 2006.04a
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• pp.14-19
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• 2006

This study examined the effect of waiting in a service queue on the evaluation of service quality focused on its overall process, mediators and moderators The conceptual model of this paper integrates key variables derived from previous studies of consumer waiting behavior. Data obtained from actual customers in service queue at a hospital was used to test the theoretical framework. First, results from the path analysis confirm that negative affect and acceptability of the wait function as mediators in the process that the perceived duration of the wait affects customer's evaluation of overall service quality. Second, the analysis of the data, with the use of moderate regression shows that disconfirmation of wait time expectations, transaction importance, stability of wait time and wait environment work as moderate variables for the relationship between perceived duration of wait and negative affect. For the relationship between perceived wait time and acceptability of the wait, on the other hand, only transaction import ante shows a significant effect as a moderator.

• Journal of Distribution Science
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• v.20 no.4
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• pp.21-31
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• 2022

Purpose: The study focuses on the distribution of brand love on customers' behavioral intention at five-star hotels in Vietnam. Furthermore, the study also assesses the role of mediating variables and moderating variable involved in the research model. Research design, data and methodology This research surveys 458 customers using the services of five-star hotels in Vietnam through questionnaires on online platforms. Data cleaning and data analysis using SPSS 25.0 software combined with Smart-PLS 3.0 software were used in the research to evaluate the measurement model and structural model. Results: From the results of the structural model evaluation, it shows the positive distribution of brand love on customers' behavioral intentions towards five-star hotels in Vietnam. The mediating roles of brand engagement, brand equity, customer motivation, and the participation of the moderating variable, customer expectations, are determined by this research model. Conclusions: Based on the study results, the distribution of brand love positively affects customers' behavioral intention at five-star hotels in Vietnam, giving recommendations that have a positive impact on customer behavioral intention. In addition, the study shows the role of mediating variables as well as exploring the moderator's (customer expectations) in the distribution of relationships between customer motivation and customer behavioral intention.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.16 no.1
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• pp.11-21
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• 2020

This study aims to develop and advance the evaluation technology for assessing PHWR safety. For this purpose, the complete loss of AC power or station blackout (SBO) was selected as a target accident scenario and the analysis model to evaluate the plant responses was envisioned into the MARS-KS input model. The model includes the main features of the primary heat transport system with a simplified model for the horizontal fuel channels, the secondary heat transport system including the shell side of steam generators, feedwater and main steam line, and moderator system. A steady state condition was achieved successfully by running the present model to check out the stable convergence of the key parameters. Subsequently, through the SBO transient analyses two cases with and without the coolant leakage via the PHTS pumps were simulated and the behaviors of the major parameters were compared. The sensitivity analysis on the amount of the coolant leakage by varying its flow area was also performed to investigate the effect on the system responses. It is expected that the results of the present study will contribute to upgrading the evaluation technology of the detailed thermal hydraulic analysis on the SBO transient of the operating PHWRs.

• Journal of Information Technology Services
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• v.13 no.1
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• pp.1-21
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• 2014

In IT service quality research, the relationship between the service quality and clients' satisfaction was the focus of many studies while in relationship quality research, the influence of trust and conflict on relationship commitment seems to be the focus. In this study, these two research streams are integrated and a theoretical research model is proposed consisting of IT service quality, satisfaction, trust and relationship commitment with conflict as a moderator for the overall psychological mechanism. As satisfaction represents emotional response while trust cognitive response, this research model integrated both emotional and cognitive aspects of relationship maintenance in the IT service context. Analysis of data collected from 262 employees of global IT service firm revealed the differential effects of reliability, responsiveness, assurance and empathy on satisfaction and trust. Also, depending upon the level of conflict, the effects of reliability and assurance were found to be moderated. Further analysis revealed more profound mechanism at work relating emotional and cognitive aspects in the psychology of relationship maintenance in IT service context. Practical implications are further discussed in the conclusion.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.532-545
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• 2022

In-depth convergence analyses for neutronics/thermal-hydraulics (T/H) coupled calculations are performed to investigate the performance of nonlinear methods based on the Fixed-Point Iteration (FPI). A simplified neutronics-T/H coupled system consisting of a single fuel pin is derived to provide a testbed. The xenon equilibrium model is considered to investigate its impact during the nonlinear iteration. A problem set is organized to have a thousand different fuel temperature coefficients (FTC) and moderator temperature coefficients (MTC). The problem set is solved by the Jacobi and Gauss-Seidel (G-S) type FPI. The relaxation scheme and the Anderson acceleration are applied to improve the convergence rate of FPI. The performances of solution schemes are evaluated by comparing the number of iterations and the error reduction behavior. From those numerical investigations, it is demonstrated that the number of FPIs is increased as the feedback is stronger regardless of its sign. In addition, the Jacobi type FPIs generally shows a slower convergence rate than the G-S type FPI. It also turns out that the xenon equilibrium model can cause numerical instability for certain conditions. Lastly, it is figured out that the Anderson acceleration can effectively improve the convergence behaviors of FPI, compared to the conventional relaxation scheme.

• Knowledge Management Research
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• v.18 no.4
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• pp.63-96
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• 2017

In a competitive organizational environment, members view completing tasks to perfection without mistakes as the requirement for success and good evaluation from others. However, unrealistically strong perfectionism can have negative effects on members' psychological states and organizational performance. This study focuses on evaluative concerns perfectionism, the negative aspect of perfectionism, based on positive psychology theory to explore the positive mechanism that comes into place in the process of strengthening organization members' resilience. For this purpose, we performed a moderated moderation analysis to investigate whether the moderating effect of leaders' social support (primary moderator) is moderated by their emotional intelligence (secondary moderator). To verify our research model, we conducted a two-part survey of 252 employees in various industries with a time interval to minimize the common method bias. Job rank and positive affectivity were set as control variables to identify the clear causal relationship among variables. Our findings showed that first, evaluative concerns perfectionism reduced resilience; second, leaders' social support positively moderated the relationship between evaluative concerns perfectionism and resilience; and third, the leaders' emotional intelligence positively moderated the two-way interaction between evaluative concerns perfectionism and the leaders' social support, confirming a moderated moderation. Our findings suggest the need for leaders to assume multidimensional roles to enhance the positive traits of organization members, especially in today's complex business environment. The implications of our findings are further discussed in relation to knowledge management and the development of organization members who exhibit evaluative concerns perfectionism, along with suggestions for future research.