• Women's Health Nursing
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• v.6 no.4
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• pp.528-548
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• 2000

The purpose of this study was to identify the effect of college women s active and passive smoking on menstrual discomfort. The subjects were 252 college female students (active smokers, 71; people who passively inhaled others smoke, 104; nonsmokers who also didn't inhale others smoke, 77). Subjects were selected from 5 colleges in North Kyong Sang Province, Korea. Data was collected from March to June of 2000 with a structured questionnaire. The instruments used for this study were the revised Menstrual Distress Questionnaire (MDQ) developed by Moos(1968), general characteristic, menstrual characteristic, and smoking characteristic scale developed by researchers. The data were analysed by the SPSS/PC+ program. The results were as follows 1. There was no statistically significant difference of menstrual discomfort level among the active smokers, those who passively inhaled others smoke, and who did not inhale others smoke(F= 2.613, p= .075). 2. The mean score of menstrual discomfort was moderate(M= 60.8008, SD= 17.9243). The level of menstrual discomfort was various (minimum score 29.00- maximum score 110.0). 3. Factors influencing menstrual discomfort were on life stress events(F= 4.057, p = .045), irregular menstrual cycle(t = 3.968, p = .047), and amount of flow during menstruation(F = 4.018, p = .019). The recommendations from this study are necessity of further studies to investigate how heavy active and passive smoking have effect on menstrual discomfort.

• Journal of Veterinary Clinics
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• v.20 no.2
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• pp.212-219
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• 2003

The effect of GnRH and/or hCG on the implantation, pregnancy, and the concentration of plasma estradiol and progesterone were studied in pregnant rats. GnRH 50, or 100ug and/or hCG 50 or 100 IU were administered once on day 2 or 9 of gestation, respectively. Rats were autopsied on days 8 or 16. Administration of GnRH on day 2 did not induce the prevention of implantation and termination of pregnancy but was able to induce termination of pregnancy administering on day 9. Administration of hCG induced delayed implantation on day 2 and termination of pregnancy on day 2 and 9. Administration of GnRH concomitant with hCG had no effect on prevention of implantation on day 2 but induced termination of pregnancy with a very increased fetal resorption on day 2 and with a moderate increased fetal resorption on day 9. Administration of GnRH concomitant with hCG on day 2 induced more increased termination of pregnancy compared to injection of GnRH or HCG and opposite result was observed on day 9. Plasma estradiol and progesterone concentrations by administering GnRH and/or hCG had no effect on the termination of pregnancy the pregnant rats.

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.541-551
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• 2004

Purpose: This study was to identify the effects of the predictive factors of Internet addiction and to develop a predictive model that explains Internet addiction among adolescents in Korea. Method: Data was collected from 664 adolescents in Puasan and Ulsan. Data analysis was done using the SPSS 10.0 Win Program for descriptive and correlational statistics and the LISREL 8.53 Win Program for Covariance structural analysis. Result: The fit of the hypothetical model to the data was moderate, it was modified by deleting four paths. Compared to the hypothetical model, the revised one had a better fit to the data($\chi^2$/df=6.50, GFI=.99, AGFI=.90, RMR=.02, NNFI=.88, NFI=.98, CN=279). Gender, friend support, and loneliness had significant direct effects on Internet addiction. The direct and indirect effect of self-esteem on Internet addiction was significant. The indirect effect of family support on Internet addiction was significant but its direct effect was insignificant. The direct and indirect effects of stress and impulsiveness on Internet addiction were significant but their total effects were insignificant. Conclusion: Finally, to decrease loneliness, and to increase family support and self-esteem, an effective intervention program and education should be developed to prevent Internet addiction of adolescents.

• Research in Community and Public Health Nursing
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• v.8 no.2
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• pp.197-210
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• 1997

This study was conducted to test the effect of cognitive stimulation training on elderly persons with dementia. The design of the research was one group in pre-test-post-test design. The subjects were nine demented persons over sixty years, with mild to moderate cognitive impairment. Training was administered by research assistants on a one to one basis for thirty to forty minutes, three times a week for eight weeks. In order to evaluate the effect of cognitive stimulation training, we measured cognitive function before and after three training sessions each. Data were analyzed using descriptive statistics and a paired t-test analysis using a spss pc package, The results are as follows: 1) The recipients of the training program showed improvement in overall cognitive functioning. The MMSK - K score, recall levels of concepts, daily tasks, personal past history and performance of word fluency were significantly increased after training. 2) There was a significant improvement in cognitive functioning over the training period: recall levels of concepts, daily tasks, past personal history and performance of word fluency significantly increased over the training period progessively, The results suggest that cognitive stimulation training is effective in improving and maintaining overall cognitive function of elderly persons with dementia.

• The Korean Journal of Community Living Science
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• v.23 no.4
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• pp.399-409
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• 2012

This research has attempted to investigate the perception of elderly women on self esteem, psychological well-being and the moderating effect of family support on self esteem and psychological well-being. Two-hundred and six of elderly women who used senior welfare centers had been participating in the research, and their questionnaires had been filled out during personal interviews. The collected data had been analysed by using SPSS Win 15.0 and the results of this study are as follows. Firstly, the level of self-esteem perceived by elderly women was a little bit higher than middle level and the level of psychological well-being appeared to be moderate. Secondly, it was found that the self esteem of elderly women affected psychological well-being and that the higher the participants perceived self esteem, the higher the level of psychological well-being. Thirdly, family support appeared to have a moderating effect in relation to self esteem and psychological well-being. As it were, the higher the perception level of elderly women was, the higher impact of their self esteem on their psychological well-being. Therefore, there needs to be a re-consideration of the importance of family support which is being weakened due to family nuclearization as well as mechanisms for improving family support.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.13 no.4
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• pp.77-86
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• 1993

Recently it is reported in many countries that highway bridges are seriously damaged due to increasing volume of overloaded heavy vehicles. The safety of bridges are highly related to the design load level and the characteristics of extreme load effect induced by traffic loads during its lifetime. The maximum structural load effect during lifetime may be produced by simultaneous loading of trucks with moderate weights on a bridge rather than by single loading of extremely heavy trucks. In this study, a simulation technique to estimate extreme load effect due to traffic loadings has been developed, in which important characteristics of traffic loadings, such as heavy vehicle proportion, traffic mode, vehicle weights, headway distribution. daily traffic volume, etc., should be properly considered. In addition. sensitivity analysis on those factors have been performed.

• Journal of Pharmaceutical Investigation
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• v.40 no.5
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• pp.269-275
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• 2010

P-gp plays a critical role in drug disposition and represents a mechanism for the development of multidrug resistance. Flavonoids, a major class of natural compounds widely present in foods and herbal products, have been shown to inhibit P-gp. Therefore, the aim of this study was to identify new candidate chemosensitizers by screening various plant extracts. The ability of natural plant extracts to inhibit P-gp activity was assessed by measuring cellular accumulation of calcein AM, daunorubicin and vincristine in P-gp overexpressing MDCKII-MDR1 cells. Among more than 800 plant extracts, eight were found to inhibit P-gp activity. Curcuma aromatica extract produced greatest inhibition, followed by Curcuma longa and Dalbergia odorifera extracts. Extracts of Aloe ferox, Curcuma zedoariae rhizome, Zanthoxylum planispinum, and Ageratum conyzoides showed moderate inhibitory effects. Curcumin and quercetin exhibited similar inhibition of P-gpmediated efflux of daunorubicin and vincristine, and flavones had a lesser effect. When chemosensitizing effect was evaluated by measuring daunorubicin sensitivity to MDCKII-MDR1 cells in the presence of natural plant extracts, Curcuma aromatica showed the most potent chemosensitizing effect based on daunorubicin cytotoxicity. In conclusion, natural plant extracts such as Curcuma aromatica can potently inhibit P-gp activity and may have potential as a novel chemosensitizers.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.3
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• pp.115-132
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• 2017

There is no absolute leadership through East and West. Just as past and present conditions are not the same, it is not easy for past leadership to apply to the present. The best leadership will be the leadership that can represent and lead the changing situation. In that sense, the creative leadership is the most appropriate leadership required by the present age. In the society, research on creative leadership is actively conducted in schools and companies, but there is no research on creative leadership in the military. This is the first study in the military about creative leadership. It is meaningful to understand the understanding of creative leadership and the applicability of the military and to provide a basis for future research. First, we measured the organizational effectiveness of creative leadership. The data were analyzed by factor analysis, correlation analysis, and regression analysis using SPSS 18.0. The results of this study were as follows. First, the organizational effectiveness of creative leadership and organizational goals and achievement were measured, and it was found that there was significant influence on the relationship between creative leadership and organizational effectiveness. I could confirm some. This would be meaningful in that it suggested the possibility of applying the leadership of the creative leadership to lead the change of society and to implement the military command.

• Journal of the Korean Society for Heat Treatment
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• v.10 no.2
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• pp.101-108
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• 1997

In high carbon steels, the cementite phase is more unstable thermally than graphite, and it can lead to a marked deterioration in the formability. Many studies have been carried out to evaluate the effect of the fundamental elements on the graphitization of cementite in high carbon steels. In this present work, the effect of Mn, Cr addition on graphitization in Fe-0.65%C-1.0%Si steel has been investigated by means of hardness testing, optical microscopy and EPMA. The nucleation of graphite may mostly depend on the dissolution rate of cementite into ferrite and the number of the nucleation sites of graphite. The graphitization was promoted by the addition of 0.1%Mn in high carbon steel, but retarded by more addition than 0.5% of Mn. By the more addition of Cr than 0.1%, the graphitization of high carbon steel was strongly retarded. Because Mn was moderate anti-graphitizer, but Cr was stroug anti-graphitizer.

• Natural Product Sciences
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• v.17 no.3
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• pp.198-201
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• 2011

Tyrosinase is one of the important enzymes in the mammalian melanin synthesis. In the process of melanin synthesis, tyrosine is oxidized to DOPA (3,4-dihydroxyphenylalanine), and DOPA is further oxidized to dopaquinone. Tyrosinase is an enzyme catalyzing this oxidation of tyrosine, so chemicals that inhibit the activity of tyrosinase can be used as skin whitening agents. In this study, we isolated five constituents from the 80% MeOH extract of Morus bombycis cortex by bioactivity-guided fractionation. We performed mushroom tyrosinase inhibition assay. As a result, 7,2',4'-trihydroxyflavanone (1), 2',4',2,4,-tetrahydroxychalcone (2), and oxyresveratrol (3) showed the more potent inhibitory effect compared to kojic acid, a well-known skin whitening agent with antityrosinase effect. Moracinoside M (4) and moracin M-3'-O-${\beta}$-D-glucopyranoside (5) also showed the moderate tyrosinase inhibitory activities.