• Journal of Korea Water Resources Association
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• v.49 no.1
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• pp.29-39
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• 2016

Accurate quantitative assessment of flood control effect of side-weir detention basin as a flood countermeasure was highly required, in which one-dimensional HEC-RAS model has been widely utilized in practice. When the submerged overflow occurred particularly driven by limited storage capacity of a given detention basin, HEC-RAS model could not be sufficiently applicable by guaranteeing acceptable accuracy without reliable benchmark dataset. From this perspective, a dedicated unsteady experiment was planned and carried out to physically realize such submerged overflow for accommodating better accuracy. Subsequently, the experimental results were applied to validate and calibrate HEC-RAS unsteady modeling to provide flood control effect of the detention basin for various inflow scenarios. After following this procedure, the modelled results indicated that there appeared within -5% of difference in stage height and maximum 2.4% accuracy to assess the flood control effect, thereby ensuring the calibrated HEC-RAS unsteady model to be accurate with practically acceptable error range.

• Journal of Periodontal and Implant Science
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• v.43 no.4
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• pp.147-152
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• 2013

Purpose: An animal periodontitis model is essential for research on the pathogenesis and treatment of periodontal disease. In this study, we have introduced a lipopolysaccharide (LPS) of a periodontal pathogen to the alveolar bone defect of experimental animals and investigated its suitability as a periodontitis model. Methods: Alveolar bone defects were made in both sides of the mandibular third premolar region of nine beagle dogs. Then, the animals were divided into the following groups: silk ligature tied on the cervical region of tooth group, Porphyromonas gingivalis LPS (P.g. LPS)-saturated collagen with silk ligature group, and no ligature or P.g. LPS application group as the control. The plaque index and gingival index were measured at 0 and 4 weeks postoperatively. The animals were then euthanized and prepared for histologic evaluation. Results: The silk ligature group and P.g. LPS with silk ligature group showed a significantly higher plaque index at 4 weeks compared to the control (P<0.05). No significant difference was found in the plaque index between the silk ligature group and P.g. LPS with silk ligature group. The P.g. LPS with silk ligature group showed a significantly higher gingival index compared to the silk ligature group or the control at 4 weeks (P<0.05). Histologic examination presented increased inflammatory cell infiltration in the gingival tissue and alveolar bone of the P.g. LPS with silk ligature group. Conclusions: An additional P.g. LPS-saturated collagen with silk ligature ensured periodontal inflammation at 4 weeks. Therefore, P.g. LPS with silk ligature application to surgically created alveolar bone defects may be a candidate model for experimental periodontitis.

• Physical Therapy Korea
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• v.9 no.1
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• pp.81-96
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• 2002

The purpose of this research was to determine the effects on the healing of fibular fractures in rabbits of low-intensity pulsed ultrasound (50 $mW/cm^2$ and 500 $mW/cm^2$) applied for periods of 4, 14 and 24 days following fibular osteotomy. Thirty-six male Japanese white rabbits were randomly divided into three groups of twelve for three treatment protocols: (1) ultrasound treatment at intensities of 50 $mW/cm^2$ and 500 $mW/cm^2$ until the 4th day following fibular osteotomy, (2) ultrasound treatment at intensities of 50 $mW/cm^2$ and 500 $mW/cm^2$ until the 14th day following fibular osteotomy, and (3) ultrasound treatment at intensities of 50 $mW/cm^2$ and 500 $mW/cm^2$ until the 24th day following fibular osteotomy. The low-intensity pulsed ultrasound was applied to only one fibula of each rabbit (these served as the experimental group). The other fibula of each rabbit served as the control group. The selection of which fibula was to be treated was made randomly. The animals were sacrificed on the 4th, 14th and 24th day after the start of ultrasound treatments. Percent of trabecular bone area and fibular radiography were carried out to compare the degree of fibular bone healing. A microscope was also used to determine any histologic changes. For statistical differences in radiological changes due to length of treatment period (4, 14 and 24 days respectively), the Wilcoxon signed-ranks test was used to compare the experimental and control groups. For statistical differences in fracture healing due to differences in ultrasound intensity, radiological studies were compared using the Mann-Whitney Test. And, to compute percentage differences in areas of trabecular bone, Two-way analysis of variance (ultrasound intensity x each group) was used. Experiment results were as follows: 1. In animals sacrificed on the 4th day, no difference was found in the radiological studies of the fibulae in the experimental and control groups (p>.05). However, experimental groups showed more rapid bone repair than control group. 2. Both radiographic and percent of trabecular bone area studies showed significant differences in rabbits sacrificed after 14 days. Fracture healing was significantly increased in the experimental group (p<.05) 3. In the animals sacrificed on the 24th day, histologic study showed rapid bone repair but fibular radiologic studies did not show statistical differences between the two groups (p>.05). 4. On the 14th day, bone union on radiograph was significantly more rapid in the treatment group with pulsed ultrasound of 50 $mW/cm^2$ than the group with 500 $mW/cm^2$ (p<.05). Histologic studies showed that both the 14 and 24 days groups had more rapid bone repair in animals treated with 50 $mW/cm^2$ ultrasound intensity than those treated with 500 $mW/cm^2$ intensity. In conclusion, it has been shown that the low-intensity pulsed ultrasound has a positive effect on bone fracture healing in the early stage and the range of pulse ultrasound from 50 $mW/cm^2$ to 500 $mW/cm^2$ is effective for fracture healing. Further study is needed to investigate the influence of pulsed ultrasound on delayed union and non-union in bone fractures and also for the clinical use of low-intensity pulsed ultrasound for bone healing in humans.

• Korean Journal of Agricultural Science
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• v.33 no.1
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• pp.85-95
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• 2006

A model experiment has been performed to get the heat transfer coefficient on the soil surface in the closed ecosystem. The heat flux on the soil surface was measured and the heat transfer coefficient was derived in the following two cases with 5-stepped control of inside air current speed. One case was that heat flowed from air to soil and the other case was that heat flowed from soil to air. Three dimensional CFD model has been set to simulate thermal environment in the closed ecosystem including soil layers. The standard $k-{\varepsilon}$ model of the CFD program was chosen for turbulence model and heating wire buried in the soil layers was set as heat source option to simulate the case when the temperature of soil surface was higher than that of inside air in the closed ecosystem. Between one case that heat flowed from air to soil and the other case that heat flowed from soil to air, there were big differences in the temperature distribution of soil layers and the heat transfer coefficient of the soil surface. The increasing rate of heat transfer coefficient on each case according to the increase of inside air current speed was similar to each other and it respectively increased linearly. But the heat transfer coefficient on the case that heat flowed from soil to air was much bigger than that of the other case. The model was validated by comparing simulated values of CFD model with measured values of the model experiment. Simulated and measured temperature of inside air and soil layers, and heat transfer coefficient of the soil surface were well accorded and the range of corrected $R^2$ was 0.664 to 0.875. The developed CFD model was well simulated in parts of the temperature of inside air and soil layers, the distribution of the inside air current speed, and heat transfer coefficient of the soil surface were able to be quantitatively analyzed by using this model. Therefore, the model would be applied and used for analysis of heat transfer coefficient between air and surface in various agricultural facilities.

• Restorative Dentistry and Endodontics
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• v.26 no.4
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• pp.296-306
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• 2001

The purpose of this study was to observe the effect of dexamethasone and osteogenic protein-1(BMP-7) on bone, cementum and periodontal tissue regeneration. A total of 60 Sprague-Dawley white female mice were selected and beta-APN was used for five days to extract the maxillary first molar a traumatically. After the extraction of the teeth, the mesiobuccal root canal was filled with Caviton$^{\circledR}$. The teeth were etched with citric acid for 1 min and coated with one of four different experimental solutions : DEX(500nM/ml), DEX(1000nM/ml), OP-1(100$\mu\textrm{g}$/ml) and OP-1(500$\mu\textrm{g}$/ml) for three minutes depending on the group. All teeth were then replanted under microscope. All replantation procedures were done within 30 minutes. Teeth that were replanted after 30 minutes of bench dry only was used as positive control. All animals were sacrificed at 3 weeks following replantation and histologic observtion was done. The results were as follows ; 1. Active root resorption rate was decreased by the order of OP-1(500$\mu\textrm{g}$/ml), DEX(1000nM/ml), OP-1(100$\mu\textrm{g}$/ml), and DEX(500nM/ml). There was statistically less root resorption in OP-1 (500$\mu\textrm{g}$/ml) and DEX(1000nM/ml) group(P<0.05). 2. The group with higher concentration of dexamethasone(1000nM/ml) had statistically more bone union compared to positive control group(P<0.05),but there were no significant differences among four experimental groups. 3. OP-1(500$\mu\textrm{g}$/ml) and DEX(1000nM/ml) groups showed less degree of inflammation compared to the OP-1(100$\mu\textrm{g}$/ml). DEX(500nM/ml), and positive control group (P<0.05). In conclusion, the group with higher concentration of OP-1 had the best results on root resorption, bone ankylosis and anti-inflammatory effects compared to the other experimental groups, but a long-term study is also necessary to evaluate the exact pharmacological effects of the drugs in the future.

• Journal of Korea Society of Digital Industry and Information Management
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• v.9 no.3
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• pp.195-209
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• 2013

Purpose of this study is to empirically consider relation between QM activity factor and management result. For this, following 6 major variables of QM activity were established as independent variable; CEO's leadership, communication, process control, standardization, full participation and education/training while satisfaction of members and improvement of quality were established as dependent variable. And, a model was set up and hypothesis verification was conducted on the basis of data collected through questionnaires. The results are summarized as follows; First, QM factors which influenced satisfaction of members in management result were CEO's leadership, communication, process control, full participation and education/training but 'standardization' factor was not statistically significant. Second, QM factors which influenced improvement of quality in management result were CEO's leadership, communication, standardization, full participation and education/training but 'process control' factor was not statistically significant. Third, among main factors of QM activity, the factor which preferentially influenced satisfaction of members was 'full participation' factor while the factor which preferentially influenced improvement of quality was 'standardization' factor. According to such results, it is required to seek a statistical method regarding QM activity with focus on the factor of 'full participation' and 'standardization' among other things for the purpose of satisfaction of members as well as improvement of quality. It is believed that implication of this study can be useful information to realize management result considering main factors of QM activity and that it also can be basic reference data to seek a statistical method for satisfaction of members and improvement of quality by grasping core factors having influence over QM activity.

• International Journal of Control, Automation, and Systems
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• v.4 no.2
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• pp.204-216
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• 2006

Latest advances in hardware technology and state of the art of mobile robot and artificial intelligence research can be employed to develop autonomous and distributed monitoring systems. And mobile service robot requires the perception of its present position to coexist with humans and support humans effectively in populated environments. To realize these abilities, robot needs to keep track of relevant changes in the environment. This paper proposes a localization of mobile robot using the images by distributed intelligent networked devices (DINDs) in intelligent space (ISpace) is used in order to achieve these goals. This scheme combines data from the observed position using dead-reckoning sensors and the estimated position using images of moving object, such as those of a walking human, used to determine the moving location of a mobile robot. The moving object is assumed to be a point-object and projected onto an image plane to form a geometrical constraint equation that provides position data of the object based on the kinematics of the intelligent space. Using the a priori known path of a moving object and a perspective camera model, the geometric constraint equations that represent the relation between image frame coordinates of a moving object and the estimated position of the robot are derived. The proposed method utilizes the error between the observed and estimated image coordinates to localize the mobile robot, and the Kalman filtering scheme is used to estimate the location of moving robot. The proposed approach is applied for a mobile robot in ISpace to show the reduction of uncertainty in the determining of the location of the mobile robot. Its performance is verified by computer simulation and experiment.

• Journal of Acupuncture Research
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• v.34 no.3
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• pp.1-11
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• 2017

Objectives : The purpose of this study was to examine the effects of Acori Graminie Rhizoma Pharmacopuncture (PA-AG) at GV20 on cerebral ischemia-induced dementia in Mice. Methods : Mice were divided into the five following groups: normal, control, acupuncture, PA-AG (17 mg/kg), and PA-AG (34 mg/kg). All groups, except the normal group, had cerebral ischemia induced by occlusion of middle cerebral artery. The control group was not treated. The acupuncture, PA-AG (17 mg/kg), and PA-GA (34 mg/kg) groups were treated every other day with a total of 6 treatments. The effect of treatment was observed by Bax, Bcl-2, Bax/Bcl-2 ratio, cytochrome c, cresyl violet, and choline acetyltransferase staining. Results : In the PA-AG (34 mg/kg) group, the intensity of Bax was decreased and the intensity of Bcl-2 was increased. The Bax/Bcl-2 ratio also decreased in the PA-AG (34 mg/kg) group. The intensity of cytochrome c protein stain was decreased in the PA-AG (17 mg/kg) group. The density of neurons stained by cresyl violet and choline acetyltransferase (ChAT) was increased in the AT, PA-AG (17 mg/kg), and PA-AG (34 mg/kg) groups when compared with that of the control group. Conclusion : PA-AG at GV20 was effective on cerebral ischemia-induced dementia in mice.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.5
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• pp.403-412
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• 2018

Recently, GNSS (Global Navigation Satellite System)-derived orthometric height determination has been studied to improve the time and cost-effectiveness of traditional leveling surveying. However, the accuracy of this new survey method was evaluated when unknown points are located lower than control points. In this study, the accuracy of GNSS-derived orthometric height was examined using TPs (Triangulation Points) to verify the stability of surveying in mountainous areas. The GNSS survey data were obtained from Mungyeong, Unbong/Hadong, Uljin, and Jangseong. Three unknown points were surrounded by more than three UCPs (Unified Control Points) or BMs (Benchmarks) following the guideline for applying GNSS-derived orthometric height determination. A newly developed national geoid model, KNGeoid17 (Korean National Geoid 2017), has been applied for determining the orthometric height. In comparison with the official orthometric heights of the TPs, the heights of the unknown points in Mungyeong and Unbong/Hadong differ by more than 20 cm. On the other hand, TPs in Uljin and Jangseong show 15-16 cm of local bias with respect to the official products. Since the precision of official orthometric heights of TPs is known to be about 10 cm, these errors exceed the limit of the precision. Therefore, the official products should be checked to offer more reliable results to surveyors. As an alternative method of verifying accuracy, three different GNSS post-processing software were applied, and the results from each software were compared. The results showed that the differences in the whole test areas did not exceed 5 cm. Therefore, it was concluded that the precision of the GNSS-derived orthometric height was less than 5 cm, even though the unknown points were higher than the control points.

• Journal of Chest Surgery
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• v.19 no.2
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• pp.225-231
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• 1986

Pericardial adhesions following open heart surgery pose a special problems, increasing the risk of cardiac reoperation because of the danger of damaging the heart, coronary artery and veins, or grafts and also the fibrous tissue may obliterate the pericardial space and eventually constrict the heart. This study was undertaken to evaluate the effect of intrapericardial urokinase and dextran 40 on the formation of pericardial adhesions in an animal model. latrogenic traumas on the pericardium were surgically induced in 30 rabbits, simulating injuries possible during actual surgery. In all rabbits, blood [1 ml] was obtained from an ear vessel and injected into the pericardium. Control group of ten rabbits did not receive any further medication, urokinase group of ten received 15, 000-20, 000 IU of urokinase, and remained ten received 1 ml of 10% dextran 40. All rabbits were sacrificed at 4 weeks. At autopsy, the development of adhesions were graded as none [Grade I], minimal [Grade II], moderate [Grade III], and severe [Grade IV]. Histological studies of the parietal pericardium and epicardium were performed. The results were as follows: 1. Group 1[Control group] showed minimal adhesion in 40%, moderate in 50%, and severe in 10% of the group. Sharp dissections were necessary in 60% of adhesions. 2. Group II [Dextran group] showed no adhesions in 20%, minimal in 60%, and moderate in 20% of the group. 3. Group III [Urokinase group] showed no adhesions in 40%, minimal in 40%, and moderate in 20% of the group. Considering in this group, the adhesion activity was significantly suppressed [60% adhesions] compared to the control group [100% adhesions] [P < 0.05]. 4. Histological findings revealed mild serosal fibrosis in none adherent group, loose fibrous connections between two layers of pericardium in minimal adhesion group, tight fibrous connections in moderate adhesion group, and marked fibrous thickening and close attachment of two surfaces were noted in severe adhesion group. These data have revealed the decreased incidence of pericardial adhesions with urokinase and dextran 40.