• Journal of Korea Technology Innovation Society
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• v.19 no.4
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• pp.711-735
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• 2016

Drug Development is very important for promoting public health and pharmaceutical industry. There has been many studies on the efficiency of drug development, but there are few studies on the drug development R&D performed by government. Since CCR model assumes unidirectional influence of input and output, it is not appropriate to analyze the efficiency of R&D due to the time-lag and spill-over effect. Also, BBC model which assumes variable returns to scale has difficulty in deriving priorities between decision making units. Recently, Range Adjusted Measure (RAM) model has been suggested in R&D efficiency analysis. RAM model measures the efficincy by eliminating inefficiencies under variable returns to scale assumption, and its strong monotonicity enables to provide clear priorities between decision making units. In this study, we analyzed the efficiency of national R&D programs for drug development using the two-step approach, including RAM model and Tobit regression analysis, and discussed major policy implications.

• Journal of Korean Institute of Industrial Engineers
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• v.42 no.5
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• pp.314-326
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• 2016

The purpose of variable selection techniques is to select a subset of relevant variables for a particular learning algorithm in order to improve the accuracy of prediction model and improve the efficiency of the model. We conduct an empirical analysis to evaluate and compare seven well-known variable selection techniques for multiple linear regression model, which is one of the most commonly used regression model in practice. The variable selection techniques we apply are forward selection, backward elimination, stepwise selection, genetic algorithm (GA), ridge regression, lasso (Least Absolute Shrinkage and Selection Operator) and elastic net. Based on the experiment with 49 regression data sets, it is found that GA resulted in the lowest error rates while lasso most significantly reduces the number of variables. In terms of computational efficiency, forward/backward elimination and lasso requires less time than the other techniques.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.39 no.12
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• pp.1269-1280
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• 1990

Owing to the need to accommodate the load variation, thermal power plants need a modern controller in order to achieve better frequency regulation, faster response and higher efficiency. For a successful development of the digital instrumentation and control system that can adopt advanced control algorithms, power plant simulator must be available for safe and convenient test. In this paper, a simple drum-type boiler model is proposed using Signal Flow Diagram that describes the system by a combination of basic time responses representing the relationships between cause and effect process variables. After verifying the model and thereafter building a simulator based on the proposed model, we tested the operation of the controller and stability or efficiency of the implemented control algorithms.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.16 no.6
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• pp.556-565
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• 2004

We have experimented an actual solar water heating system acquiring real data for one year period. On the basis of the operation data, it is necessary to predict the system performance such as collector efficiency and solar fraction, and to analyze the economical efficiency for system optimal design. To estimate the performance of actual systems through simulation, valid modelling for components consisting of the system should be accompanied. The present study is focused on the modelling for load patterns and operating control conditions. We proposed two load models: concentration model which gathers real loads as a meaningful group and distribution model which disperses real loads with time. If grouping of the load distribution is suitable, the predicted values by the concentration model approaches to those by the distribution model close to actual load pattern apparently. As a result, both of them are in good agreement with those by experiment.

• Phonetics and Speech Sciences
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• v.6 no.1
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• pp.105-117
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• 2014

The purpose of this study was to (1) establish a Korean adult normative database for phonatory aerodynamic measures obtained with the KayPENTAX Phonatory Aerodynamic System (PAS) Model 6600, (2) investigate the intra-subject reliability of these measures across three testing sessions, and (3) examine the effect of gender on those measures. 170 healthy normal speakers (70 men and 100 women) between the ages 18 and 49 years participated in the study. The PAS protocol of maximum phonation and voicing efficiency were conducted and 25 measures were obtained. All aerodynamic measures taken in this study demonstrated high intra-subject reliability in clinical aspect. There were no significant effect of gender in the measures related to sound pressure and subglottal pressure. However, significant differences for gender were found for phonation time, airflow rate, expiratory volume, aerodynamic power, SPL range, pitch range, mean pitch, aerodynamic resistance, and aerodynamic efficiency. Clinicians should be aware of significant gender effects in some aerodynamic parameters when interpreting the data obtained from PAS.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.551-554
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• 2002

The paper discusses new approach for machining operation simulation using enhanced Z map algorithm. To extract the required geometric information from NC code, suggested algorithm uses supersampling method to enhance the efficiency of a simulation process. By executing redundant Boolean operations in a grid cell and averaging down calculated data, presented algorithm can accurately represent material removal volume though tool swept volume is negligibly small. Supersampling method is the most common form of antialiasing and usually used with polygon mesh rendering in computer graphics. The key advantage of enhanced Z map model is that the data structure is same with conventional Z map model, though it can acquire higher accuracy and reliability with same or lower computation time. By simulating machining operation efficiently, this system can be used to improve the reliability and efficiency of NC machining process as well as the quality of the final product.

• Journal of Korea Society of Industrial Information Systems
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• v.17 no.7
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• pp.59-70
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• 2012

This paper provides a model which is used for SOA based system's quality evaluation. This model make evaluation with "Reliability, Usability, Efficiency, Usability and Maintainability", these five aspects which were reference from ISO/IEC 9126. A systems based on SOA was tested by this model in these five aspects. As the results of the evaluation this system satisfied 61.45% users including Service Requester and Service Registry.

• Transactions of the Korean Society of Automotive Engineers
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• v.10 no.5
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• pp.1-8
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• 2002

For gasoline engines, a three-way catalytic converter that has the maximum efficiency at stoichiometric air/fuel ratio is used to clean up the exhaust gas. So a precise air/fuel ratio control is necessary to maximize the catalytic conversion efficiency, For a transient condition, a fred-forward air/fuel ratio control method that estimates the air mass inducted into a cylinder is being used. In this study, a fuel injection map that makes an accurate air/fuel ratio control possible was constructed for the very same transient condition. For the same condition above, intake air model and fuel model were refined so that fuel injection values based on air mass through a throttle valve and intake manifold pressure are equal to the map values.

• Journal of Microbiology and Biotechnology
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• v.13 no.5
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• pp.789-793
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• 2003

This study focused on the optimization of the illumination method for efficient use of light energies in a photobioreactor. In order to investigate the effect of radiator position, a model simulation study was carried out using Synechococcus sp. PCC 6301 and an internally radiating photobioreactor as a model system. The efficiency of light transfer in a photobioreactor was analyzed by estimating the average light intensity in a photobioreactor. The simulation result, indicate that there exists an optimal position of internal radiators, and that the optimal position varies with radiator number and cell concentration. When light radiators are placed at the optimal position, the average light intensity is about 30% higher than that obtained by placing radiators at the circumstance or center of a photobioreactor. The method presented in this work may be useful for improving light transfer efficiency in a photobioreactor.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.13 no.3
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• pp.200-208
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• 2001

In indoor temperature control of a heat pump, a reduction in energy consumption is very important. However, most control schemes for heat pumps have focused only on control performance such s settling time and steady-state error. In this paper, the model predictive control (MPC) which includes the energy-related variable in this cost function is proposed. By computing the control signal minimizing this cost function, the trade-off between energy reduction and temperature control performance can be obtained. Since the MPC required the process model, the dynamic mode of a heat pump is also obtained by the system identification technique. Performance of the proposed MPC considering energy efficiency is compared with the two other control schemes. It si shown that the proposed scheme can consume less energy thant hte others in achieving similar control performance.