• 한국컴퓨터정보학회논문지
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• 제12권5호
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• pp.273-284
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• 2007

본 논문은 재구성가능생산시스템 환경에서 e-MarketPlace를 통한 거래상황을 도입한 주기적 검토 재고모형을 연구한다. 의사결정권자는 고객의 확률적 수요를 만족시키기 위해서 생산용량/생산량을 확장/축소하거나 e-Marketplace를 통해 긴급으로 재고를 보충/처리한다. e-MarketPlace로부터의 거래 시 재고의 보충/처리에 걸리는 리드타임은 시스템의 생산리드타임보다 짧지만, 단위거래비용(구매/판매비용)은 생산용량/생산량을 한 단위 확장/축소하는 비용보다 높기 때문에 각 대안들의 비용-리드타임간의 trade-off가 고려된다. 추가적으로 e-MarketPlace로부터 재고를 보충하거나 생산용량을 확장하는 경우 그 수량에 따른 규모의 경제를 고려하기 위해 고정 비용이 포함된다. 우리는 제안되는 모형의 최적 정책형태를 규정하기 위해 동적계획모형과 K-convexity 기법을 적용하고, base stock policy와 (s,S) type policy의 조합으로 구성된 최적 생산-재고관리 정책을 제시한다.

• 한국화재소방학회논문지
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• 제33권1호
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• pp.76-84
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• 2019

성능위주설계(PBD)의 주방 화재시뮬레이션을 위해 요구되는 목재 가연물의 CO 및 Soot yields 정보를 제공하기 위하여, 개방 콘 칼로리미터를 활용한 실험이 수행되었다. 싱크장 제작에 널리 사용되는 MDF와 PB를 대상으로 함수율, 표면 가공처리 방식 및 색상에 따라 총 8가지의 시편이 검토되었다. 주요 결과는 다음과 같다. 동일 두께의 시편이라도 표면 가공처리 방법에 따라 깊이 방향으로의 화재확산과 관련된 열적 관통시간에 상당한 변화가 발생됨이 확인되었다. MDF와 PB series의 CO yield는 유염 연소 구간에서 연소 모드별 그리고 표면 가공처리 방식에 따라 큰 변화가 없다. 그러나 유염 연소모드에 비해 훈소 모드에서는 약 10배의 높은 $y_{CO}$가 측정되었다. 반면에 Soot yield는 연소 모드와 표면 가공처리 방식에 따라 상당한 차이를 보였다. 특히 유염 연소모드와 표면이 가공 처리된 시편에서 보다 높은 $y_{soot}$가 확인되었다. 마지막으로 PBD의 주방 화재시뮬레이션을 위하여 측정된 MDF와 PB의 $y_{CO}$ 및 $y_{soot}$ 적용 방안이 논의되었다.

• 약학회지
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• 제49권6호
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• pp.484-489
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• 2005

Streptococcus pmeumoniae is the leading cause of pneumonia and bacterial meningitis. The current polysaccharide vaccine has been reported ineffective in elderly adults and children less than 2 years of age. Thus, in recent many researchers have been focused on a different approach, DNA vaccine. In our laboratory we developed a Streptococcus pneumoniae DNA (SPDNA) vaccine. This SPDNA vaccine was formulated by inserting the region encoding part of the capsule in the S. pneumoniae into the LAMP-1. In present work, with use of the SPDNA vaccine we attempted to establish a certain methodology useful for evaluation of effectiveness and immunoresponse of a DNA vaccine. Results showed that the subcutaneous route was the most effective for production of antisera specific for S. pneumoniae in mice. By isotyping analyses, IgM, IgGl, IgG2a, and IgG2b were determined. In addition, INF-$\gamma$ and IL-4 were predominantly detected. Combination of those data resulted in a pattern of IgGl < IgG2a=IgG2b and INF$\gamma\>$ >IL-4, which indicates the inmmunity towards the Thl response predominantly; furthermore, the SPDNA vaccination induced resistance of the CD4+T lymphocyte-depleted mice against disseminated pneumococcal infection. These data appear to be possibly due to activation of CDS8+T cell-activation. Taken together, this methodology can be applied for evaluating efficacy and mode of action of a DNA vaccine as minimum critera.

• Industrial Engineering and Management Systems
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• 제11권2호
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• pp.188-195
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• 2012

This paper presents a new mode of expressing a 3D assembly work for creating a 3D CG animation without judgment by human from minimal required information. In the field of manufacturing, there are favorable movements in the utilization of 3D CAD for 3D simulation to shorten lead time for product development and pre-production. But simulating an assembly work has troubles to need huge quantity of manually input data. This paper discusses what minimal necessary information for creating 3D CG animations of assembly works is, focusing on the features of assembly works. Furthermore, a new mode of expressing a 3D assembly work is proposed as "state/change transition diagrams" (SCTD), which express arbitrary scenes in an assembly work as "state" and describe a sequential assembly work with "state" and "change", and the outline of its stepwise generation algorithm is also described. SCTD can be converted to a 3D CG animation of an assembly work without judgment by human. This paper focuses on the creating 3D CG animation of assembly works which workers use only their both hands.

• International Journal of Industrial Entomology and Biomaterials
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• 제11권2호
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• pp.81-86
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• 2005

The mode of transmission, effect on fecundity, hatching and tissues specificity of a microsporidian $(Lb_{ms})$ recovered from Lamerin breed of the silkworm Bombyx mori L. was studied and compared with standard strain Nosema bombycis. Peroral inoculation of $Lb_{ms}$ or N. bombycis to zeroday of $4^{th}$ instar larvae of silkworm was the most suitable method for producing information on development of stage specific mortality, pupation and obtaining infected adults for transovarial transmission studies. It was observed that pupal mortality, the percentage of moths emerged and the percentage of moths infected were significantly high in N. bombycis infected batches as compared $(Lb_{ms})$ in all the three tested breeds of the silkworm. However no significant difference was observed in larval mortality. The fecundity and hatchability was not affected significantly in $(Lb_{ms})$ infected adults, however significant reduction in egg production, fecundity, hatchability and increased egg retention was observed in mother moths infected with N. bombycis. The $(Lb_{ms})$ is transmitted both horizontally and vertically at lower rate due to its low rate of proliferation. The trans ovarial transmission of $(Lb_{ms})$ to the $F_1$ progeny generation through eggs averaged only $61.33\pm5.10\%$ whereas N. bombycis was transmitted at $100\%$. The $(Lb_{ms})$ had low oral infectivity and low transovarial transmission in silkworm B. mori.

• 환경위생공학
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• 제14권3호
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• pp.130-138
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• 1999

The feasibility of municipal sewage sludge digestion was investigated by using thermophilic anaerobic sequencing batch reactor(ASBR). One-day settle time was enough for the high performance of solid-liquid separation. The conversion of semi-continuous mode to sequencing batch mode is easily achieved without any adverse effects, although the large amount of sludge equal to the volume ratio of 0.3~06 to reactor volume was added in the feed step of the start-up. The ASBRs had higher conversion capability of organics to biogas than the control reactor. Gas yields of the ASBRs were increased by the average of 50% over the control reactor across a range of hydraulic retention time(HRT)s from 10days to 5days. The thermophilic reactors showed higher gas production than mesophilic reactor. Removal efficiencies of organic matter exceeded 80% on the basis of supernatants, except that at the reactor. Solid-liquid separation was essential in the performance of the ASBR, especially, at the lower HFT. The ASBRs were highly efficient in the retention of activated biomass within the reactor. thus compensating for increased equivalent organic loading rate through increased solids retention times followed by the increased solids, while maintaining shorter HRTs.

• Journal of Microbiology
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• 제45권2호
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• pp.122-127
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• 2007

Factors indicating culture status of two Spirulina platensis strains were monitored in a batch mode cultivation for 36 days. Changing mode in all factors showed a common turning point, indicating shift of cell or culture status. Mean biomass productivity was highly sustained until day 22, chlorophyll a concentration peaked on day 22, pH value was > 12 on day 22, coil number was abruptly shortened on day 22, and floating activity was sustained at greater than 79% after day 22, indicating that day 22 is a criterion reflecting phase-transfer in cell physiology in a batch culture system. Many of these changes may have been caused by increased pH, suggesting that pH control is essential for mass production of S. platensis. Fluctuations in floating activity were likely induced by the number of cellular gas vacuoles. Consequently, coil number per trichome and floating activity of S. platensis could readily act as simple indicators for determination of culture status or harvesting time of cells.

• 한국지능시스템학회논문지
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• 제24권5호
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• pp.554-561
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• 2014

Hybrid wind Diesel stand-alone power systems are considered economically viable and effective to create balance between production and load demand in remote areas where the wind speed is considerable for electric generation, and also, electric energy is not easily available from the grid. In Wind diesel hybrid system, the wind energy system is the main constitute and diesel system forms the back up. This type of hybrid power system saves fuel cost, improves power capacity to meet the increasing demand and maintains the continuity of supply in the system. Problem we face in this system is that even after producing enough power through wind turbine system, considerable portion of this power needs to be dumped due to short term oversupply of power and to maintain the frequency within close tolerances. As a result remaining portion of total energy supplied comes from the diesel generator to overcome the temporal energy shortage. This scenario decreases the overall efficiency of hybrid power system. In this study, efficient Simulink modeling for wind-diesel hybrid system is proposed and some simulations study is carried out to verify the feasibility of the proposed scheme.

• Journal of Microbiology and Biotechnology
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• 제5권4호
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• pp.224-228
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• 1995

Fed-batch fermentations were conducted to produce human lipocortin-I (LC1), a potential anti-inflammatory agent, from recombinant Sacchromyces cerevisiae carrying a galactose-inducible expression system. The cell growth, expression level of LC1, and the plasmid stability were investigated under various LC1 induction modes performed by three different galactose feeding strategies. Galactoe was fed to induce the expression of LCl from the beginning (initial induction) of culture or when the cell concentration reached 120 OD (mid-phase induction) or 300 OD (late induction). Among the three galactose-induction modes tested, the initial induction mode yielded the best result with respect to a final expression level of LC1. Fedbatch fermentation with initial induction mode produced LC1 at a conentration of 220 mg/l, which corresponded to 1.38- and 1.53-fold increases over those produced by mid-phase and late induction modes.

• 수산해양기술연구
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• 제58권4호
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• pp.345-351
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• 2022

In this study, the target strength for multi-frequency (38 kHz, 120 kHz, 200 kHz) of juvenile silverfish (Pleuragramma antarcticum) was estimated using by the KRM (Kirchhoff-ray mode) model. The body shape of the silverfish was described by a picture and the body length of nine individuals ranged in 1.8 cm to 8.8 cm. The maximum TS_cm according to the total length for the constant term (b20) was -92.93 dB at 38 kHz, -86.63 dB at 120 kHz, and -85.89 dB at 200 kHz, respectively. The averaged TS_cm according to total length for the constant term (b20) was -100.0 dB at 38 kHz, -93.0 dB at 120 kHz, and -106.9 dB at 200 kHz, respectively.