• 제목/요약/키워드: Mode Sequence

검색결과 292건 처리시간 0.03초

최대 엔트로피 모델을 이용한 막횡단 단백질 예측 (Maximum Entropy Approach to Transmembrane Protein Prediction)

  • 윤성희;차정원;박승수
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2005년도 한국컴퓨터종합학술대회 논문집 Vol.32 No.1 (B)
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    • pp.664-666
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    • 2005
  • 막횡단 단백질(Transmembrane Protein)은 약물표적(drug target)으로 신약개발로 대표되는 바이오 산업에서 중요한 연구대상이 되고 있다. 막횡단 단백질의 구조는 실험적 기법 또는 컴퓨터 모델링 기술을 이용하여 연구되고 있으며 컴퓨터 모델링 방법 중에서는 Hidden Markov Mode(HMM)에 기반한 시스템들이 좋은 성능을 보이고 있다. 그런데 이러한 시스템들은 구조형성에 관여하는 단백질의 다양한 특성에 대한 지식은 많이 고려하고 있지 않다. 만약 이러한 특성들이 고려된다면 구조 예측에 효과적인 보다 지능적인 모델을 만드는데 도움을 줄 수 있을 것이다. 본 논문은 단백질의 특성과 관련한 다양한 정보들을 융합하는데 효율적인 최대엔트로피모델(Maximum Entropy Model)을 이용하여 막횡단 단백질의 서열(sequence)로부터 막횡단 지역을 예측하는 방법을 제시하고자 한다.

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Accurate analytical solution for nonlinear free vibration of beams

  • Bayat, M.;Pakar, I.
    • Structural Engineering and Mechanics
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    • 제43권3호
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    • pp.337-347
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    • 2012
  • In this study, Hamiltonian Approach (HA) is applied to analysis the nonlinear free vibration of beams. Two well-known examples are illustrated to show the efficiency of this method. One of them deals with the Nonlinear vibration of an electrostatically actuated microbeam and the other is the nonlinear vibrations of tapered beams. This new approach prepares us to achieve the beam's natural frequencies and mode shapes easily and a rapidly convergent sequence is obtained during the solution. The effects of the small parameters on the frequency of the beams are discussed. Some comparisons are conducted between the results obtained by the Hamiltonian Approach (HA) and numerical solutions using to illustrate the effectiveness and convenience of the proposed methods.

Buckling characteristics and static studies of multilayered magneto-electro-elastic plate

  • Kiran, M.C.;Kattimani, S.C.
    • Structural Engineering and Mechanics
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    • 제64권6권
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    • pp.751-763
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    • 2017
  • This article deals with the buckling behaviour of multilayered magneto-electro-elastic (MEE) plate subjected to uniaxial and biaxial compressive (in-plane) loads. The constitutive equations of MEE material are used to derive a finite element (FE) formulation involving the coupling between electric, magnetic and elastic fields. The displacement field corresponding to first order shear deformation theory (FSDT) has been employed. The in-plane stress distribution within the MEE plate existing due to the enacted force is considered to be equivalent to the applied in-plane compressive load in the pre-buckling range. The same stress distribution is used to derive the potential energy functional. The non-dimensional critical buckling load is accomplished from the solution of allied linear eigenvalue problem. Influence of stacking sequence, span to thickness ratio, aspect ratio, load factor and boundary condition on critical buckling load and their corresponding mode shape is investigated. In addition, static deflection of MEE plate under the sinusoidal and the uniformly distributed load has been studied for different stacking sequences and boundary conditions.

비선형 육상이동위성 채널에서 OFDM M-ary PSK 시스템의 수신성능 개선방안 (Performance Improvement of OOFDM M-ary PSK System In a Nonlinear Land Mobile Satellite Channel)

  • 허정철;한문용;이상진;서종수
    • 한국통신학회논문지
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    • 제26권4B호
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    • pp.520-527
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    • 2001
  • 육상이동위성 채널에서 고속 광대역의 정보를 효율적으로 전송하기 위한 최적 방안으로 OFDM(Orthogonal Frequency Division Multiplexing) M-ary PSK를 들 수 있다. 그러나 가입자 단말기 또는 위성중계기의 송신단 고출력 증폭기(HPA : High Power Amplifier)를 전력효율적인 비선형 mode에서 동작할 때, OFDM M-ary PSK 시스템의 최대 전력 대 평균전력의 비(PAPR : Peak-to-Average Power Ratio)가 부바송파 개수만큼 선형적으로 커져 단일 반송파 변조방식에 비해 비선형 왜곡에 의한 성능 열화가 심각하다. 본 논문에서는 이와 같은 성능 열화를 개선하기 위하여 전송채널에서 대역효율과 BER(Bit Error Rate) 성능이 우수한 PC(Parallel Combinatory) OFDM 방식과 개선된 PAPR을 가지는 PTS(Partial Transmit Sequence) OFDM 방식을 결합한 Combined PC & PTS OFDM 방식을 제안하고 그 성능을 분석하였다.

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안벽구조물에 대한 Centrifuge 모형실험과 수치해석 (Centrifuge Model Test and Numerical Analysis on Coastal Structure)

  • 유남재;김동건;전상현
    • 산업기술연구
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    • 제29권B호
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    • pp.65-72
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    • 2009
  • In this paper centrifuge model tests and numerical analysis on the coastal structure on the marine deposits of sand were performed to investigate the behavior of structure and foundation under the condition of wave action in field. In centrifuge model experiments, construction sequence of coastal structure such as preparation of sand deposit, excavation replacement, rubble mound with crushed stones and installment of coastal structure was reconstructed and the behavior of ground settlement during stage of construction was observed during tests. For the final stage of simulating the horizontal movement of coastal structure due to wave force, horizontal load was applied by horizontal loading apparatus being specially designed so that horizontal displacement of structure could be observed. Numerical analysis were also carried out and its results were compared with test results to assess the property of centrifuge mode experiments with respect to the behavior of structure as well as ground.

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Detection and Diagnosis of Sensor Faults for Unknown Sensor Bias in PWR Steam Generator

  • Kim, Bong-Seok;Kang, Sook-In;Lee, Yoon-Joon;Kim, Kyung-Youn;Lee, In-Soo;Kim, Jung-Taek;Lee, Jung-Woon
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2002년도 ICCAS
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    • pp.86.5-86
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    • 2002
  • The measurement sensor may contain unknown bias in addition to the white noise in the measurement sequence. In this paper, fault detection and diagnosis scheme for the measurement sensor is developed based on the adaptive estimator. The proposed scheme consists of a parallel bank of Kalman-type filters each matched to a set of different possible biases, a mode probability evaluator, an estimate combiner at the outputs of the filters, a bias estimator, and a fault detection and diagnosis logic. Monte Carlo simulations for the PWR steam generator in the nuclear power plant are provided to illustrate the effectiveness of the proposed scheme.

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LIGA 공정을 이용한 평면형 광소자용 Ni 마스터 제작 (Fabrication of Ni master for the replication of planar optical devices by LIGA process)

  • 김진태;정명영
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 춘계학술대회
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    • pp.945-949
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    • 2003
  • LIGA(Lithographie Galvanoformung Abformung), a fabrication method for the production of microstructrues with a high aspect ratio, is now playing an important role in a fabrication of polymeric optical waveguide device as the replication processes have been developed such as hot embossing and injection molding. The present report deals with the fabrication of Ni master used for the replication of multi-mode polymeric optical waveguide. With the basic technological features in the sequence of the LIGA technique, we fabricated Ni master with 12 channel microstructures of $100\;{\times}\;100{\mu}m\;^2{\times}\;60mm$, and achieved an accuracy of ${\pm}1\;{\mu}m$. Manufactured polymeric optical wavegude with the same using hot embossing process has also the same accuracy and approved its mass production capability.

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Combined BOLD fMRI and Transcranial Magnetic Stimulation Study: Evaluation of Ipsilateral Motor Pathway of Stroke Patients

  • 배성진;장용민;장성호;변우목;강덕식
    • 대한자기공명의과학회:학술대회논문집
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    • 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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    • pp.104-104
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    • 2001
  • Purpose: In this study, we investigated the possible motor pathways of hemiplegic stroke patients usin combined TMS and BOLD fMRI approach and evaluated the correlation between TMS a fMRI methods. Method: Four subjects, who demonstrated left hemiplegia after stroke, are included. TMS was performed using a Dantec Mag2 stimulator (Dantec Company, USA) in single puls mode with figure eight-shaped coil. Following TMS localization, The BOLD T2*-weight images were acquired with echo planar imaging sequence (TR = 1.2 sec, TE = 60 msec, and flip angle = 90). Motor activation was studied by means of a repetitive fing flexion-extension task. The stimulation protocol comprised 10 cycles of alternating activati and rest (10 images per cycle). Total 60 cycles were performed and each cycle take abou 1.5 sec. The resulting images were then analyzed with STIMULATE (CMRR, U, o Minnesota) to generate functional maps using a student t-test (p < 0.0005) and cluste analysis.

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직교이방성 복합적층판의 초음파 탐사에 관한 연구 (A Study on the Inspection of Orthotropy Composite Laminate plates Using Ultrasonics)

  • 나승우;임광희;양인영
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2000년도 추계학술대회 논문집
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    • pp.583-586
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    • 2000
  • This work ethibits how susceptive the shear ultrasonic waves are to a little misoriented plies according to the angle variation of shear ultrasoic waves $0^\circ$ , $45^\circ$ and $90^\circ$. Also, it is shown that shear waves, particularly the transmission mode with the transmitter and receiver perpendicular to each other, have high sensitivity for detecting anomalies in fiber orientation and ply layup sequence that may occur in the manufacturing of composite laminates. Experimental results are agreed with modeling solutions which were based on decomposition of shear wave polarization vector as it propagates through the composite laminates. This wave appeared considerably to be sensitive to CFRP composites to the thickness direction along in-plane fibers.

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층간균열이 존재하는 균일 열유동하의 섬유강화 적층복합재료의 열응력해석 (Thermal Stresses in a Laminated Fiber-Reinforced Composite Containing an Interlaminar Crack Under a Uniform Heat Flow)

  • 최형집;오준성;이강용
    • 대한기계학회논문집
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    • 제18권4호
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    • pp.887-902
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    • 1994
  • Within the framework of anisotropic thermoelasticity, the problem of an interlaminar crack in a laminated fiber-reinforced composite subjected to a uniform heat flow is investigated. Under a state of generalized plane deformation, dissimilar anisotropic half-spaces with different fiber orientations are considered to be bound together by a matrix interlayer containing the crack. The interlayer models the matrix-rich interlaminar region of the fibrous composite laminate. Based on the flexibility/stiffness matrix approach, formulation of the current crack problem results in having to solve two sets of singular integral equations for temperature and thermal stress analyses. Numerical results are obtained, illustrating the parametric effects of laminate stacking sequence, relative crack size, crack location, crack surface partial insulation, and fiber volume fraction on the values of mixed mode thermal stress intensity factors.