• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.34 no.7
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• pp.28-34
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• 2006

In general engineering problems, the purpose of an optimization is to get optimal design variables. It is the same problem to fix the total amount of the design variables and to judge the optimal mixing proportions of the design variables. That is to say, we can recompose the engineering problems in the concepts of the mixture amount experiments. The goal of mixture amount method is to get the response surfaces of varying both the mixing proportion of component and the total amount of the mixture. The solution of the aircraft fuselage optimization problem is obtained by the mixture amount method and genetic algorithm. In this study, it is shown that the mixture amount method can be utilized for the aircraft structural optimization problem. Also, this method in this study can be applied for the optimization problems over 12 design variables which is impossible for D-optimal design.

• Journal of the Korean Institute of Gas
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• v.12 no.3
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• pp.81-84
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• 2008

In this paper, the research was applied the mixture gas of Propane-DME (dimethyl ether) for being commercialization to residential gas ranges. In order to examine a correspondence between Korean Standard and thermal efficiency characteristics at each burner, experiments were performed with 100% Propane and the mixture gas of 80% Propane-20% DME. The experimental results were shown that the higher a mixture ratio of DME was used, the lower a thermal efficiency was gained. Those were due to low caloric value of DME. With 80% Propane-20% DME mixture gas, one of residential gas ranges was not satisfied the condition for the thermal efficiency value, 40%, Korean Standard. Consequently, the research needs about the standard for being commercialization to the mixture gas of Propane-DME.

• The Korean Journal of Food And Nutrition
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• v.36 no.4
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• pp.244-252
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• 2023

This study was conducted to provide basic data on the antioxidant activity, inhibition of adipocyte differentiation and reactive oxygen species (ROS) production of a mixture of Brassica juncea extract (BJE) and fermented black rice fraction (BRF). We investigated the total phenol content, total flavonoid content, antioxidant effects (DPPH radical scavenging, ABTS radical scavenging, reducing power, FRAP and ORAC assay) and anti-obesity activity of the mixture in 3T3-L1 cells. Our results showed that the total phenol and flavonoid content increased with increasing BRF mixture ratio. The antioxidant activity increased as the BRF mixture ratio increased. In addition, BJE and BRF mixtures did not show any cytotoxicity during the 3T3-L1 differentiation period. During adipocyte differentiation, BJE and BRF mixtures significantly inhibited lipid accumulation and ROS production compared to the control group. These results warrant further experiments to develop an anti-obesity functional food using a mixture of BJE and BRF.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.1D
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• pp.33-39
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• 2012

More and more pavements are suffering from damage these days due to the below-zero winter temperatures and frequent snowfalls. From this research, the freeze-thawing mechanisms of pavements will be observed, and the freeze-thawing resistance of porous asphalt concrete mixture is to be evaluated according to various assessment methods. The investigation was conducted through applying rigid and flexible pavements to freeze-thawing resistance experiments, which include various experiments such as deformation rate measurements, Lottman tests, repeated cyclic freeze-thawing experiments, stripping resistance tests and so on. Test results revealed that the porous asphalt concrete had less deformations according to temperatures compared to dense-graded asphalt concrete due to the 20% void gap. In addition, according to the freeze-thawing repetition experiments which are effected by moisture, the porous asphalt concrete mixture showed superior resistance to repeated cyclic freeze-thawing compared to other asphalt concrete mixtures due to the drainage and the voids within the specimen.

• Journal of Korean Society for Quality Management
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• v.44 no.2
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• pp.245-264
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• 2016

Purpose: This article focuses on the reviewing the papers published in the Journal of the Korean Society for Quality Control (JKSQC) and the Journal of the Korean Society for Quality Management (JKSQM) since 1965, in the area of design of experiments. In this paper, moreover, some other contents of another statistical quality control areas is included. Methods: The reviewed articles are classified into the three main categories: theory and application of experimental designs, response surface methodology and mixture experiments, and roust designs. Some omitted papers in the other areas of reviewing works are also included in this paper, and the contents and relationships of the published articles are examined and summarized in each sub-field. Results: We summarize the reviewed papers in the chronological road-maps for each sub-field, and outline the relations of the connected papers. We provide comments on the contents and the contributions of the reviewed papers. The future direction of the research in the theory and application areas of experimental designs can be provided by the contents of this research. Conclusion: The diverse topics on the improving the quality in the various industry fields are studied and published on the theory, methodology and the empirical application in the fields of designs of experiments. We can see that the Korean Society for Quality Management (KSQM) has tremendously contributed on the improvement of quality in the manufacturing and service industries by publishing the reviewed articles in this paper.

• Natural Product Sciences
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• v.10 no.3
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• pp.134-139
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• 2004

In this study, an immunoactivity of panaxtriol ginsenosides Re and Rg1 against infection due to Candida albicans was investigated. The ginsenosides were extracted from Red Ginseng with 85% ethanol and heat-treatment and were analyzed by HPLC on water-acetonitrile as a mobile phase. The HPLC analysis revealed that the extract contained ginsenosides Re and Rg1, which were eluted as a combined peak. By agar diffusion susceptibility, the mixture of Re and Rg1 had no growth-inhibitory activity on C. albicans yeast cells. However, in animal tests BALB/c mice given the mixture of Re and Rg1 intraperitoneally (Lp.) before intravenous (Lv.) infection with live C. albicans yeast cells had longer mean survival times (MST) than MST of control mice groups that received only buffer solution instead of Re and Rg1. In experiments 60% of the ginsenosides-treated mice survived the entire duration of the 50-day observation. The Re and Rg1 mixture induced production of nitric oxide when interacted with RAW 264.7 macrophage cell line. In addition, the mixture caused morphological change of the macrophages. These data indicate that immunostimulation by the Re and Rg1 may be responsible for the protection of mice against disseminated candidiasis.

• Journal of the Korean Society of Safety
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• v.24 no.5
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• pp.13-20
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• 2009

The risk assessment of thermal hazard to identify chemical or process hazard during early process developments have been considered. The early identification of thermal hazards associated with a process, such as rapid heats of reaction, exothermic decompositions, and the potential for thermal runaways before any large scale operations are undertaken. This paper presents to evaluate the safe operating parameters/envelope for exist plant operations. The assessment of thermal hazard with operating conditions such as amount of process materials, inhibitor, and catalyst on esterification process in manufacture of concrete mixture agents are described. The experiments were performed by a sort of calorimetry with the Multimax reactor system as a screening tool. The aim of the study was to evaluate the thermal risk of process material and mixture in terms of safety security to be practical applications in esterification process. It suggested that we should provide the thermal hazard of reaction materials to present safe operating conditions with cause of accident through this study.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.2
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• pp.465-470
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• 2015

The curing of epoxy asphalt mixture depends on the chemical reaction of epoxy resin and the curing agent. The curing level of epoxy asphalt mixture needs to be predicted in order to decide traffic opening time and to establish further construction plans. In this study, chemical analysis of the prediction model was executed to expand the applicability of the previous prediction model. Consequently, the curing level prediction model of epoxy asphalt concrete mixture was proposed using the concentration ratio and the acid value ratio. According to the results of outdoor curing experiments, the final prediction model showed that the correlation coefficient is greater than 0.971. Precise prediction results of different composition epoxy asphalt were obtained by reflecting the chemical composition ratios in the curing level prediction model.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.12
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• pp.1692-1698
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• 2002

A diesel engine has various merits such as high thermal-efficiency, superior fuel consumption and durability. Therefore the number of diesel engine in the world is increasing. As the seriousness of environmental pollution increases in the world, the method to reduce the noxious materials of $CO_2$, NOx and P.M. is very important subject to correspond to exhaust gas regulations. A new concept, so called premixed charge diesel combustion(PCCI), is focused among the various corresponding manners. In this study, we investigated the mixture formation within the cylinder with injection timing using GTT simulation code and also compared combustion characteristics of PCCI engine with that of commercial diesel engine. From this experiments, it could be found that homogeneous mixture formation was observed according to advance of injection timing and simultaneous reduction of NOx and Soot in injection timing of BTDC 60$^{\circ}$.

• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.1
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• pp.26-30
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• 2002

A droplet fractionation method was previously developed to concentrate a dilute nonfoaming protein solution. In that earlier study with invertase, it was demonstrated that droplets created by ultrasonic energy waves could be enriched up to 8 times that of the initial dilute invertase solution. In this study, a mixture of bromelain (a foaming protein) and invertase (a nonfoaming protein) is investigated as a preliminary step to determine if droplet fractionation can also be used to separate a non-foaming protein from foaming proteins. The foaming mixture containing bromelain is first removed by bubbling the binary mixture with air. After the foam is removed, the protein rich air-water interfacial layer is skimmed off (prior to droplet fractionation) so as not to interfere with the subsequent droplet production from the remaining bulk liquid, rich in non-foaming protein. Finally, sonic energy waves are then applied to this residual bulk liquid to recover droplets containing the non-foaming protein, presumed to be invertase. The primary control variable used in this droplet fractionation process is the pH, which ranged for separate experiments between 2 and 9. It was observed that the maximum overall protein partition coefficients of 5 and 4 were achieved at pH 2 and 4, respectively, for the initial foaming experiment followed by the post foaming droplet fractionation experiment.