• Communications for Statistical Applications and Methods
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• v.4 no.1
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• pp.33-39
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• 1997

Tsutakawa(1988) proposed a mixed model for using empirical Bayes method to study the geographic variability in mortality rates of a disease. In particular cases of the analysis in mortality rate, we need to consider the effect of time. If observed data are collected annually for the time period, then time effect will be emphasized. Here, an extended model for estimating the geographic effect and the mortality rates of the disease with time effect is proposed.

• The Journal of Korean Academic Society of Nursing Education
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• v.29 no.4
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• pp.339-351
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• 2023

Purpose: The purpose of this study is to identify the educational needs of virtual reality simulations that can be applied to novice nurses during the waiting period before starting work in a hospital. Methods: A convergent mixed methods was used. The survey data were collected from 230 novice nurses, and a focus group interview was conducted with 6 new nurses. The data were collected from November 2022 to January 2023. Descriptive statistics, a frequency analysis, independent t-test, and an Importance-Performance Analysis were performed using SPSS 24.0. Results: Appropriate topics for virtual reality simulation education were indicated to be medications and intravenous injections, which are high priority topics in quantitative and qualitative research. The novice nurses wanted group activity training three to four times a week for two weeks before beginning work in a hospital. They also wanted an immersive virtual reality system based on a real hospital environment. Conclusion: Based on the above results, this study provides basic data for the development of a virtual reality simulation education that can improve the adaptation of novice nurses to clinical practice. A strategy was suggested to utilize the waiting time before beginning work in a hospital as educational time.

• Clinical Nutrition Research
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• v.12 no.2
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• pp.126-137
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• 2023

Hemodialysis (HD) patients face a common problem of malnutrition due to poor appetite. This study aims to verify the appetite alteration model for malnutrition in HD patients through quantitative data and the International Classification of Functioning, Disability, and Health (ICF) framework. This study uses the Mixed Method-Grounded Theory (MMGT) method to explore various factors and processes affecting malnutrition in HD patients, create a suitable treatment model, and validate it systematically by combining qualitative and quantitative data and procedures. The demographics and medical histories of 14 patients were collected. Based on the theory, the research design is based on expansion and confirmation sequence. The usefulness and cut-off points of the creatinine index (CI) guidelines for malnutrition in HD patients were linked to significant categories of GT and the domain of ICF. The retrospective CIs for 3 months revealed patients with 3 different levels of appetite status at nutrition assessment and 2 levels of uremic removal. In the same way, different levels of dry mouth, functional support, self-efficacy, and self-management were analyzed. Poor appetite, degree of dryness, and degree of taste change negatively affected CI, while self-management, uremic removal, functional support, and self-efficacy positively affected CI. This study identified and validated the essential components of appetite alteration in HD patients. These MM-GT methods can guide the selection of outcome measurements and facilitate the perspective of a holistic approach to self-management and intervention.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.1
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• pp.237-243
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• 2015

In recent image processing, active researches have been made along with rapid development in digital times. However, it is know that the image degradation occurs due to various external factors in the processes of image data processing, transmission and storage, and the main reason of image degradation is due to the noise. Typical methods to remove the noise are CWMF(center weighted median filter), A-TMF(alpha-trimmed mean filter) and AWMF(adaptive weighted median filter) and these methods have a little bit lacking noise reduction characteristics in mixed noise environments. Therefore, in order to remove the mixed noise, image restoration filter processing algorithm was suggested in this paper which processes by applying the median value of the mask and space weighted value after noise judgment. And for the objective judgment, it was compared with existing methods and PSNR(peak signal to noise ratio) was used as a judgment standard.

• The Korean Journal of Food And Nutrition
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• v.31 no.5
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• pp.653-667
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• 2018

This study evaluated the quality characteristics, the presence of polyphenolic compounds, and radical scavenging activity of rice cooked along with various mixed grains (barley, black soybean, adzuki beans, foxtail millet, proso millet, sorghum, glutinous rice) by following two different cooking methods (normal and pressure cooker). The amylogram and water characteristics of mixed grains showed significant differences based on the presence of different types of mixed grains. The chromaticity, palatability characteristics, presence of phenol compounds, and radical scavenging activity of rice cooked along with different mixed grains showed significant differences according to the nature of mixed grains. Total polyphenol contents of before cooking, cooked-rice added to mixed grains cooked in the normal cooker and a pressure cooker were 4.46~5.16, 0.58~0.93 and 0.65~0.96 mg GAE/g, and total flavonoid contents were 250.74~548.89, 129.26~207.04 and $127.41{\sim}218.15{\mu}g\;CE/g$, respectively. The DPPH radical scavenging activity of before cooking, cooked-rice added to mixed grains cooked in the normal cooker and a pressure cooker was 79.25~181.61, 22.07~53.64 and 7.51~39.97 mg TE/100 g, and ABTS radical scavenging activity was 203.25~328.24, 47.28~84.94 and 58.27~99.51 mg TE/100 g, respectively. Accordingly, it is necessary to different combinations of mixed grains according to the cooking method at home and grain industry.

• Journal of the Korean Chemical Society
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• v.55 no.3
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• pp.379-384
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• 2011

The critical micelle concentration (CMC) and the counter ion binding constant (B) for the mixed micellizations of DBS (sodium dodecylbenzenesulfonate), SDS (sodium dodecylsulfate), and Brij 30 (polyoxyethylene(4) lauryl ether) at $25^{\circ}C$ in pure water were determined by the use of electric conductivity and surface tension measuring methods. Various thermodynamic parameters ($X_i,\;{\gamma}i,\;C_i,\;a_i^M,\;{\beta}$, and ${\Delta}H_{mix}$) were calculated and compared with each other mixed surfactant system by means of the equations derived from the nonideal mixed micellar model. The results show that the SDS molecule interacts more strongly with Brij 30 molecule than DBS molecule and that the SDS/Brij 30 mixed surfactant system has the greatest negative deviation from the ideal mixed micellar model and the SDS/DBS mixed system has followed almost the ideal mixed micellar model.

• Korean Journal of Pharmacognosy
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• v.1 no.3
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• pp.93-99
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• 1970

There have been reported by several workers for the isolation and determination of the amine derivatives as Metbylephedrine Hydrochloride and Ephedrine Hydrochloride adopting neutralization method, steam distillation method, non-aqous titration method, ion-exchange resin method, titration method after acetylation, colorimetric method, gravimetric method, iodine titration method and gas chromatography. Those methods mentioned in above, can be practically applied for the sample which is not mixed one mith the other amine compounds. Presently, it has not shown on the isolative determination of the mixed sample of amine derivatives. In this paper, it is discussed on the isolative determination of Methylephedrine Hydrochloride as the tertiary amine compound and Ephedrine Hydrochloride as the secondary amine compound. According to the results of the experiment, it could be summarized as follows: 1. There is no time-variation on the color reaction of Methylephedrine Hydrochloride and Ephedrine Hydrochloride with the color reagent, bromcresolgreen. And Methylephedrine Hydrochloride and Ephedrine Hydrochloride, respectively, can be determined spectrophotometrically by means oft his color reaction. 2. For the isolation of Methylephedrine Hydrochloride and Ephedrine Hydrochloride from the mixed sample, Methylephedrine Hydrochloride can be eluted by chloroform, while Ephedrine Hydrochloride by the mixed solvent of chloroform and ethylalcohol (2:1), from the celite column adsorbed at pH6.4 followed by extraction with ether undersodium hydroxide alkali re action. 3. When the sample is mixed with quinine hydrochloride, dihydrocodeine bitartate, and noscapine, these mixed compounds can be eliminated by means of stram distillation. 4. When the sample is mixed with chlorpheniramine maleate, dextromethorphan hydrobromide and diphenhydramine hydrochloride, the mixed compounds can be eliminated by means of steam distillation and celite adsorption column chromatography, In conclusion, the isolative determination method for Methylephedrine Hydrochloride and Ephedrine Hydrochloride studied in this paper, indicates with the excellent reproducibility and accuracy.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2009.05c
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• pp.65-68
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• 2009

Recently, the knowledge access about concrete might be 2 methods. One is approach about advanced and new technical development through the institute journal, the other is construction technology which is using at construction fields. However, there is no research for the interrelationship between them. So, this paper investigates the demands on construction fields at the ready mixed concrete plants on the 4 cities, the characteristics of the products like the maximum size of coarse aggregate and slump, and the extension of market on the high strength and flow ability concrete in 2000 and 2008. Moreover, this study would like to propose the investigation about diversification of construction materials for the fine construction cultures and development of the ready mixed concrete to the engineers at the construction fields.

• Journal of Power System Engineering
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• v.9 no.2
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• pp.33-39
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• 2005

Experiments are performed to study the mixed convection flow and heat transfer in an inclined parallel plates with the upper part cooled and the lower part heated uniformly. The Reynolds number ranges from $4.0{\times}10^{-3}\;to\;6.2{\times}10^{-2}$, the angle of inclination, ${\theta}$, from 0 to 45 degree from the horizontal line, and Pr of the high viscosity fluid is 909. In this paper, the PIV(Particle image velocimetry) with TLC(Thermo-sensitive liquid crystal) tracers is used for visualizing and analysis. This method allows simultaneous measurement of velocity and temperature field at a given instant of time. Quantitative data of the temperature and velocity are obtained by applying the color-image processing to a visualized image, and neural network is applied to the color-to-temperature calibration. This paper describes the methods, and presents the quantitative visualization of mixed convection. From this study, it is found that the flow pattern can be classified into three patterns which are affected by Reynolds number and the angle of inclination.

• Archives of Reconstructive Microsurgery
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• v.23 no.1
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• pp.1-7
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• 2014

Purpose: Recent studies have reported on application of fibrin glue composed of fibrinogen and thrombin to nerve anastomosis, which can be another candidate for vessel anastomosis. However, no research regarding the risk and effectiveness of thrombin in microvascular free tissue transfer has been reported. Therefore, the aim of study is to determine the risk and effectiveness of thrombin on microvascular free tissue transfer through clinical cases. Materials and Methods: Twenty-five patients underwent free flap reconstruction for soft tissue defect or bone exposure in our institute from March 2011 to February 2014. In the group using thrombin, dissolved powder thrombin (5,000 IU/amp) was mixed with 10 mL normal saline. Saline mixed with thrombin was applied on the flap, recipient, and around vessel anastomosis. In the control group, free flap was performed using the same method, except using thrombin. We analyzed the results between the two groups. Results: All flaps survived. The group using thrombin included 14 patients and the control group included 11 patients. Hematoma was found in two cases, respectively, in each group. The group using thrombin showed lower incidence of hematoma than the control group. No difference in survival rate of the flap was observed between the thrombin group and the control group. Conclusion: Results of this study showed that use of saline mixed with thrombin in free tissue transfer may be safe and effective for prevention of hematoma formation in the recipient site.