• Title/Summary/Keyword: Mixed Extracts

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Anti-Obesity Effect of Herbal Mixture Powder and Water Extracts in Mice Fed a High Fat Diet (나복자, 의이인, 백복령, 다엽, 차전자피로 구성된 혼합분말제(HP)와 진피, 산사, 옥미수, 양총피로 구성된 혼합열수추출물(HE)이 고지방식이로 유도된 비만마우스에 미치는 항비만 효과)

  • Youn, Jedong;Choi, Yunhee
    • Journal of Society of Preventive Korean Medicine
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    • v.19 no.1
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    • pp.131-144
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    • 2015
  • Objective : This study was conducted to investigate anti-obesity effects of mixed-Powder(Raphani Semen, Coicis Semen, Poria, Plantaginis Testa & Theae folium)(HP) & mixed water extract(Citri Pericarpium, Crataegi Fructus, Maydis Stigma, Allium Skin) (HE) in mice fed a high-fat diet. Method : 50 Female ICR mice were divided into six groups; Normal group (Ve), high-fat diet group (Po), Po+HP(0.6g/kg) group(HP), Po+HE(1g/kg) group(HE), Po+(HP+HE) group(HPE), Po+(HP+HE)*2 group(DHPE). For 8 weeks, these groups were fed their respective diets. Body weight, liver weight and weights of adipose tissues, GOT/GPT index changes & Blood Glucose index changes were measured respectively. Lipid profiles in serum were analyzed by kit of blood. Results : Groups HP, HE, HPE, DHPE had significantly reduced body weight, liver weight, adipose tissue weights and GOT/GPT index, blood glucose index compared to the Po group. Also, serum triglyceride and total cholesterol, low density lipoprotein, were significantly reduced when compared to the Po group. Group G1 had significantly increased high density lipoprotein levels. Conclusion : Mixed powder (HP) & mixed water extract (HE) show anti-obesity effects in mice fed a high-fat diet.

Antimutagenicity and Cytotoxicity Effects of Woorimil Wheat Flour Extracts Added with Wild Herb and Seaweed Powder (산채 및 해조분말을 첨가한 우리밀 밀가루 열수출물의 항돌연변이성 및 암세포 성장 억제효과)

  • 함승시;이상영;최면;황보현주
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.6
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    • pp.1177-1182
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    • 1998
  • The antimutagenic and cancer cell growth inhibitory effects of woorimil contained herb and seaweed powders were examined. While woorimil itself showed only 40% antimutagenic effect on S. typhymurium TA98 against 4NQO(0.15 g/plate), water extracts of mountain herbs and seweeds including Comfrey, wormwood, Kale, Angelica utilis and pine leaves showed 80~90% antimutagenicity. On the other hand, these extracts along with woorimil showed 68 to 80% antimutagenic activities. Low antimutagenic activities of less than 50% were shown when these extracts were tested on TA98 against Trp P 1(0.5 g/plate), but high antimutagenic activities of 80~93.3% were shown on TA100. Water extracts of Capsella bursa pastoris and Allium grayi exhibited 60~80% of the activites in cytotoxicity tests of woorimil water extracts(0.5mg/ml) on human lung carcinoma cell. A549 showed 10% cell growth inhibitory effect. When mixed with Comfrey and Angelica utilis extracts, it showed 23~25% inhibition and other extracts showed only 12~23% inhibition. Cytotoxicity test of woorimil extracts on human liver cancer cell Hep3B revealed 20% inhibition. The additions of pine needle extracts, Angelica utilis and Comfrey showed 33%, 29% and 25% inhibition, respectively. But other extracts showed only 20% inhibition.

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Influences of Sosiho-Tang Extracts and Prednisolone on the Toxicity of Carbon tetrachloride in Rats (랏트에 있어서 사염화탄소 독성에 대한 소시호탕 엑기스와 prednisolone의 영향)

  • 안영근;김성오;정대영
    • Environmental Analysis Health and Toxicology
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    • v.4 no.3_4
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    • pp.61-75
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    • 1989
  • Influences of the concurrent administration of carbon tetrachloride and prednisolone on the biometric, biochemical and histological findings were investigated in male rats prefered twice Sosio-Tang extracts at intervals of 24 hours. Influences of the concurrent admininistration of carbon tetrachlorides and prednisolone twice a week respectively on the findings were also investigated in male rats fed freely diet and. tab water mixed with Sosio-Tang extracts for six weeks. 1. Sosio-Tang extracts. decreased the toxicity of carbon tetrachloride. This was proved by biometric, biochemical and histological findings. 2. Prednisolone increased the toxicity caused by carbon tetrachloride. 3. The group treated with Sosio-Tang extracts. and prednisolon concomitantly increased the toxicity compared with Sosio-Tang extracts. treated group.

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Screening on Allogeneic Mixed Lymphocyte Culture Inhibitory Activity for the Extracts of Marine-Derived Microorganisms (해양미생물 추출물의 동종세포반응 (Allogeneic Mixed Lymphocyte Culture) 억제효능 검색)

  • Yun, Keum-Ja;Oh, Keun-Hee;Lee, Dong-Sup;Choi, Hong-Dae;Kang, Jung-Sook;Son, Byeng-Wha
    • Korean Journal of Pharmacognosy
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    • v.42 no.4
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    • pp.354-360
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    • 2011
  • In order to screen new allogeneic mixed lymphocyte culture (allo-MLR) inhibitor which is expected to be immunomodulating drug lead, we have investigated allo-MLR inhibitory activity on the marine-derived symbiotic microorganisms (1,895 strains) from the marine algae. The potent inhibitory activities (over 45% inhibition of proliferation at 10 and 2 ${\mu}g/ml$) without cytotoxicity were observed in the extracts of 46 strains. While, the significant stimulating activities (over 100% proliferation at 10 and 2 ${\mu}g/ml$) without cytotoxicity were observed in the extracts of 5 strains. In the second assay using 46 bioactive strains, 14 strains exhibited again significant allo-MLR inhibitory activity. Finally, 11 strains among the 14 strains inhibited proliferation and IFN-${\gamma}$ production of CD4+ T cells during the stimulation with specific antigen in the third assay. On the basis of above results, the marine algae is nice source for isolation of immunomodulating microorganism, and the marine algae-associated microorganism is also nice target for development of the new immunomodulating drug lead.

Ultrafiltration and Adhesive Characteristics of Alkali-soluble Extracts from Radiata Pine Barks (소나무수피 알칼리추출물의 한외여과 및 접착제 제조특성)

  • Cho, Nam-Seok
    • Journal of the Korean Wood Science and Technology
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    • v.26 no.1
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    • pp.29-37
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    • 1998
  • Alkali-soluble extracts were prepared from medium-sized barks of Radiata pine(Pinus radiata). There are difficulties in the production of extracts with uniform quality and in the preparation of adhesives with suitable viscosity. Ultrafiltration using an Amicon cell was subjected to fractionate extracts according to molecular sizes in order to overcome the above problem. The filtration efficiency was studied by using thin channel filtration systems. Adhesive manufacturing was also examined. Removal of particles greater than 0.45m from the extracts increased both filtration speed (flux) and yields of solids in the filtrates. Ultrafiltration with PM 10 membrane was very effective to fractionate and concentrate the extracts. Stiasny precipitates from the filtrates obtained by PM 10 membrane were very lower than that(83%) of the retentates. This ultrafiltration method was efficient for obtaining high yield purified phenolic compounds(mainly polyflavanoids) and thus important for preparing wood adhesives from barks. The extracts were shown excessive high viscosities at the concentrations required for adhesive formulation, but this high viscosity and short gelation time was reduced by lowering pH of the extracts and addition of urea. The highest bonding strength of plywoods(340g/$m^2$ of adhesive spreads) was achieved with adhesive formulated by 100parts of mixed alkali extracts and urea(70/30,w/w), 10parts of p-formaldehyde and 3.5parts of wheat flour at pH 6, and by hot pressing at the conditions of 12kg/$cm^2$ at $120^{\circ}C$ for 10 minutes.

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Development of Soil Binder Using Plant Extracts (식물추출액을 이용한 지반 고결제 개발)

  • Park, Sung-Sik;Choi, Sun-Gyu;Nam, In-Hyun
    • Journal of the Korean Geotechnical Society
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    • v.28 no.3
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    • pp.67-75
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    • 2012
  • This paper presents an environment-friendly sand cementation method by precipitating calcium carbonate using plant extracts. The plant extracts contain urease like $Sporosarcina$ $pasteurii$, which can decompose urea into carbonate ion and ammonium ion. It can cause cementation within sand particles where carbonate ions decomposed from urea combine with calcium ions dissolved from calcium chloride or calcium hydroxide to form calcium carbonate. Plant extracts, urea and calcium chloride or calcium hydroxide were blended and then mixed with Nakdong River sand. The mixed sand was compacted into a cylindrical specimen and cured for 3 days at room temperature ($18^{\circ}C$). Unconfined compression test, SEM and XRD analyses were carried out to evaluate three levels of urea concentration and two different calcium sources. As urea concentration increased, the unconfined compressive strength increased up to 10 times those without plant extracts because calcium carbonate precipitated more, regardless of calcium source. It was also found that the strength of specimen using calcium chloride was higher than that of specimen using calcium hydroxide.

Studies on the Antioxygenic Substances in Panax ginseng Roots -I. The Antioxidative Action of Various Solvent Extracts of Panax ginseng Roots- (인삼중의 항산화물질에 관한 연구 -제 1 보 : 인삼의 각종 용매 추출물의 항산화작용-)

  • Paik, Tai-Hong;Hong, Jeong-Tai;Hong, Soon-Yoog
    • Korean Journal of Food Science and Technology
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    • v.14 no.2
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    • pp.130-135
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    • 1982
  • The antioxidative action of petroleum ether, chloroform, chloroform-methamol (2 : 1, v/v), methanol and methanol-water extracts of Panax ginseng roots in the autoxidation of mixed methyl esters of unsaturated fatty acids (MEUFA) was investigated in vitro. All of the extracts of Panax ginseng roots possessed antioxidative activity and inhibited the formation of hydroperoxides in the autoxidation of mixed methyl esters of unsaturated fatty acids (MEUEA). The induction period in the autoxidation of MEUFA was extended by the addition of each extract. The antioxidative activity was more prominent with chloroform and chloroform-methanol (2 : 1, v/v) extracts than with other extracts. The antioxidative activity of each extract estimated by Olcott's oven test and the measurement of peroxide value (POV) showed a similar tendency. From the results obtained, it was conclude that extracts of Panax ginseng roots had remarkable antioxidative activity in the autoxidation of MEUFA in vitro.

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Growth Response of Kentucky Bluegrass and Creeping Bentgrass by Foliar Spray with Chitosan Formulation and Seaweed Extracts during Fall Season (키토산 제형과 해조추출물의 엽면살포가 가을철 Kentucky Bluegrass와 Creeping Bentgrass의 생육 반응)

  • Chang, Tae-Hyun;Yoon, Jeong-Ho
    • Asian Journal of Turfgrass Science
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    • v.25 no.2
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    • pp.195-201
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    • 2011
  • The seaweed (Ascophyllum nodosum) extracts and chitosan formulations were sprayed on species of creeping bentrgass (Agrostis palustris Huds) cultivar "Penn A1" and species of Kentucky bluegrass (Poa pratensis L.) mixed cultivars (Midnight 33%, Moonlight 33%, Prosperity 33%) during fall season in sod farm. Turf color, chlorophyll contents and NDVI (Normalized Difference Vegetation Index) to affect turf qualities were investigated. There were detected significantly difference on chlorophyll contents and DNVI with seaweed extracts and chitosan formulations treatments. The contents of chlorophyll and NDVI on species of Kentucky bluegrass mixed cultivars and species of creeping bentgrass cultivar "Penn A1" were significantly increased by foliar spray with chitosan formulations and seaweed extracts. There was not a significantly difference on leaf color in two species within cultivars. These results suggested that chitosan formulations and seaweed extracts may help for turfgrass managements in the golf course during fall season.

Residual Solvents and Mineral Contents in Ginseng Extracts with Different Extracting Conditions (추출조건에 따른 인삼농축액 중의 잔류용매 및 무기물 함량)

  • Lee, Seon-Hwa;Kim, Woo-Seong;Kim, Yong-Mu;Hong, Yeong-Pyo;Ahn, Yeong-Soon;Park, Heung-Jai;Kim, Ok-Hee
    • Journal of Environmental Science International
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    • v.16 no.1
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    • pp.39-44
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    • 2007
  • This study was conducted to investigate the contents of residual solvents and mineral components(11 kinds) in ginseng extracts with different extracting conditions(5 types) and commercial ginseng extract products(domestic, imported). Fine root was extracted with solution having various ethanol concentration after hexane treatment. Among 5 type extracts, residual solvent(hexane) was detected ginseng extracts treated ethanol mixed with hexane. But extracts that dried after soaked in hexane wasn't detected hexane. Mineral components(Al, Mn, Fe, Cu and Zn) were detected in fine root and 5 types of extracts. The contents of mineral components between fine root and extracts with various extracting conditions were similar, however, extracts that dried after soaked in hexane showed the lower amount in Al, Fe, Pb than the others. In comparison with commercial ginseng ex-tract products(domestic, imported), the distribution pattern of mineral was similar but the contents were a little different.

Investigation of some Natural Product Extracts as Corrosion Inhibitors for Mild Steel in Acid Mediu

  • Subramania, A.;Sathiya Priya, A.R.;Saravanan, S.;Abdul Nasser, A.J.;Vasudevan, T.
    • Corrosion Science and Technology
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    • v.4 no.6
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    • pp.231-235
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    • 2005
  • The inhibitive effect of extracts of tamarind seeds and jackfruit seeds, curry leaves and henna leaves on corrosion of mild steel in 1M HCl solution have been studied by weight loss, potentiodynamic polarization and impedance measurements. Results obtained from the electrochemical techniques were in good agreement with weight loss results. From the weight loss data, the values of surface coverage ($\Theta$) and corrosion rate were calculated. The inhibition efficiency (IE) increased with increasing inhibitor concentration in 1M HCl solution. In all the cases the adsorption of the natural product extracts on the mild steel surface from 1M HCl follows the Langmuir adsorption isotherm relationship. Potentiodynamic polarization studies reveal the fact that all the four natural product extracts act as mixed type inhibitors. The decrease in the inhibition efficiency follows the order: Extracts of jackfruit seed>henna leaves>curry leaves>tamarind seed.