• 제목/요약/키워드: Ming General

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Dexamethasone Downregulates Expressions of 14-3-3β and γ-Isoforms in Mice with Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection

  • Tsai, Hung-Chin;Chen, Yu-Hsin;Yen, Chuan-Min;Chung, Li-Yu;Wann, Shue-Ren;Lee, Susan Shin-Jung;Chen, Yao-Shen
    • Parasites, Hosts and Diseases
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    • 제57권3호
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    • pp.249-256
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    • 2019
  • Steroids are commonly used in patients with eosinophilic meningitis caused by A. cantonensis infections. The mechanism steroids act on eosinophilic meningitis remains unclear. In this mouse experiments, expressions of 14-3-3 isoform ${\beta}$ and ${\gamma}$ proteins significantly increased in the CSF 2-3 weeks after the infection, but not increasedin the dexamethasone-treated group. Expression of 14-3-3 ${\beta}$, ${\gamma}$, ${\varepsilon}$, and ${\theta}$ isoforms increased in brain meninges over the 3-week period after infection and decreased due to dexamethasone treatment. In conclusion, administration of dexamethasone in mice with eosinophilic meningitis decreased expressions of 14-3-3 isoform proteins in the CSF and in brain meninges.

명장(明將) 남방위(藍芳威)의 조선 활동과 현존 문물 고찰

  • 박현규
    • 중국학논총
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    • 제72호
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    • pp.47-70
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    • 2021
  • In this paper, the focus was on the review of Ming General Nan Fangwei's activities during the Choson period and existing relevant historical artifacts & literacy works. Nan Fangwei's hometown was Jiangxi(江西) Changjiang(昌江; Jingdezhen景德鎭). Unfortunately, it has not been known where his descendants migrated later. During Jingdezhen Riot(景德鎭民亂), he went to serve as the head of the grass roots. After surrendering, he became a general in the Ming military base. During Jeongyujae War(丁酉再亂), he entered Chosun as a Youji general(遊擊) and participated in dozens of large and small battles. However, the defeat of Jungro-gun (中路軍) led him to a feud with the Ming's military authorities and to return him, which gave him a hard time to be forcibly dislodged to a remote region. Nan Fangwei established Namwon Guanwang Shrine(南原 關王廟). Since then, it has been preserved in Namwon Wangjeong-dong(王亭洞) through several reconstruction and reconstruction works. In addition, he took good care of people by strictly cracking down on their subordinates with high integrity and virtuous deeds at the military base. Being deeply touched by his morality and virtue, the people of Gongju(公州) established 'Youji general Nan Fangwei Jongdeokbi(〈遊擊將藍公種德碑〉)'. In addition, when he had his leisure time, he collected Korean Chinese poems from various figures and edited and published 'Chosun Poetry Collection(《朝鮮詩選全集》)', which he played a catalyst to promote high-quality Korean poems to Chinese literacy community.

NECESSARY AND SUFFICIENT CONDITIONS FOR THE EXISTENCE OF SOLUTIONS TO OPERATOR EQUATIONS

  • Park, Sehie
    • 대한수학회보
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    • 제27권2호
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    • pp.151-155
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    • 1990
  • Recently, H.Z.Ming [7] obtained a necessary and sufficient condition for the existence of a solution to a general operator equation. In the present paper, we obtain such conditions in general forms and give some examples. We begin with the well-known Fan-Browder fixed point theorem, from which we deduce two general theorems on such necessary and sufficient conditiions. We give some examples of such conditions, which are improved versions of fixed point theorems of Halpern-Bergman [5], Ky Fan [3], [4], Kaczynski [6], Reich [9], Schauder [10], Tychonoff [11], and Ming [7]. In fact, we restate Ming's result in its correct form. The following is known as the Fan-Browder fixed point theorem [1], [2].

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Could Tumor Size Be A Predictor for Papillary Thyroid Microcarcinoma: a Retrospective Cohort Study

  • Wang, Min;Wu, Wei-Dong;Chen, Gui-Ming;Chou, Sheng-Long;Dai, Xue-Ming;Xu, Jun-Ming;Peng, Zhi-Hai
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권18호
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    • pp.8625-8628
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    • 2016
  • Background: Central lymph node metastasis(CLNM) is common in papillary thyroid microcarcinoma (PTMC). The aim of this study was to define the pathohistologic risk grading based on surgical outcomes. Materials and Methods: Statistical analysis was performed to figure out the optimal cut-off values of size in preoperative ultrasound images for defining the risk of CLNM in papillary thyroid microcarcinoma. Receiver operating characteristic curves (ROC) studies were carried out to determine the cutoff value(s) for the predictor(s). All the patients were divided into two groups according to the above size and the clinic-pathological and immunohistochemical parameters were compared to determine the significance of findings. Results: The optimal cut-off value of tumor size to predict the risk of CLNM in papillary thyroid microcarcinoma was 0.575 cm (area under the curve 0.721) according to the ROC curves. Significant differences were observed on the multifocality, extrathyroidal extension and central lymph node metastasis between two groups which were divided according to the tumor size by the cutoff values. Patients in two groups showed different positive rate and intensity of Ki67. Conclusions: The size of PTMC in ultrasound images are helpful to predict the aggressiveness of the tumors, it could be an easy predictor for PTMC prognosis and assist us to choose treatment.

朱熹 「理一分殊」 的 <西銘> 詮釋模式再考察 (The Re-inspection on The Explanatory Model ofXi Ming of Chu Hsi'sThought of "Li Yi Fen Shu")

  • 임악창
    • 철학연구
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    • 제141권
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    • pp.167-185
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    • 2017
  • 주희(朱熹)는 정이가 제기한 '리일분수(理一分殊)'의 명제를 계승하여 십 수년의 노력을 기울인 후에 최종적으로 "서명해(西銘解)"를 지었다. 이로부터 '리일분수(理一分殊)'의 사상은 "서명(西銘)"을 해석하는 모델이 되었으며, "서명(西銘)"의 기조(基調)를 확정하는 역할을 하게 되었다. '리일분수론(理一分殊論)'은 처음에는 "서명(西銘)"의 윤리학적 의의를 표현하는 명제였다. 그런데 주희(朱熹)의 일생을 통해 볼 때 '리일분수론(理一分殊論)'은 단순히 "서명(西銘)"의 윤리학적 의의에 국한되지 않고, 보편적인 철학적 의의를 포함하며, 사물의 일반과 특수의 관계를 표현하는 데에도 사용되었다. 전자는 협의의 '리일분수론(理一分殊論)'이고, 후자는 광의의 '리일분수론(理一分殊論)'이라고 할 수 있다. 이 글에서는 광의적인 리일분수론(理一分殊論)에 대해서는 논하지 않고, 주희(朱熹)가 확립한 "서명(西銘)"을 해석하는 모델로서의 협의의 리일분수론(理一分殊論)을 연구 대상으로 삼고자 한다. 학술계의 선행연구 중에서 어떤 학자들은 '리일분수(理一分殊)'의 명제가 "서명(西銘)"의 의미와 일치한다고 생각하지만, 다른 어떤 학자들은 일치하지 않는다고 주장한다. 이러한 두 종류의 사고방식은 확연히 상반되는 입장이다. 이 글에서는 리일분수(理一分殊) 사상에 의한 주희(朱熹)의 "서명(西銘)" 해석이 어떤 부분에서는 "서명(西銘)" 본래의 뜻과 일치하기도 하지만, 또다른 어떤 부분에서는 서로 부합하지 않는 곳도 있다는 입장을 견지한다. 달리 말하면, 주희(朱熹)가 리일분수론(理一分殊論)으로 "서명(西銘)"을 해석할 때, '공헌(貢獻)'과 '제한('制限)'의 의미를 동시에 지닌다는 것이다. 즉, 리일분수론(理一分殊論)에 의한 주희(朱熹)의 "서명(西銘)" 해석은 그 의미를 확장시킨 부분도 있지만, "서명(西銘)" 본래의 목표로부터 멀어진 부분도 있다는 의미이다.