• Title/Summary/Keyword: Ming General

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Dexamethasone Downregulates Expressions of 14-3-3β and γ-Isoforms in Mice with Eosinophilic Meningitis Caused by Angiostrongylus cantonensis Infection

  • Tsai, Hung-Chin;Chen, Yu-Hsin;Yen, Chuan-Min;Chung, Li-Yu;Wann, Shue-Ren;Lee, Susan Shin-Jung;Chen, Yao-Shen
    • Parasites, Hosts and Diseases
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    • v.57 no.3
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    • pp.249-256
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    • 2019
  • Steroids are commonly used in patients with eosinophilic meningitis caused by A. cantonensis infections. The mechanism steroids act on eosinophilic meningitis remains unclear. In this mouse experiments, expressions of 14-3-3 isoform ${\beta}$ and ${\gamma}$ proteins significantly increased in the CSF 2-3 weeks after the infection, but not increasedin the dexamethasone-treated group. Expression of 14-3-3 ${\beta}$, ${\gamma}$, ${\varepsilon}$, and ${\theta}$ isoforms increased in brain meninges over the 3-week period after infection and decreased due to dexamethasone treatment. In conclusion, administration of dexamethasone in mice with eosinophilic meningitis decreased expressions of 14-3-3 isoform proteins in the CSF and in brain meninges.

명장(明將) 남방위(藍芳威)의 조선 활동과 현존 문물 고찰

  • Park, Hyeon-Gyu
    • 중국학논총
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    • no.72
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    • pp.47-70
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    • 2021
  • In this paper, the focus was on the review of Ming General Nan Fangwei's activities during the Choson period and existing relevant historical artifacts & literacy works. Nan Fangwei's hometown was Jiangxi(江西) Changjiang(昌江; Jingdezhen景德鎭). Unfortunately, it has not been known where his descendants migrated later. During Jingdezhen Riot(景德鎭民亂), he went to serve as the head of the grass roots. After surrendering, he became a general in the Ming military base. During Jeongyujae War(丁酉再亂), he entered Chosun as a Youji general(遊擊) and participated in dozens of large and small battles. However, the defeat of Jungro-gun (中路軍) led him to a feud with the Ming's military authorities and to return him, which gave him a hard time to be forcibly dislodged to a remote region. Nan Fangwei established Namwon Guanwang Shrine(南原 關王廟). Since then, it has been preserved in Namwon Wangjeong-dong(王亭洞) through several reconstruction and reconstruction works. In addition, he took good care of people by strictly cracking down on their subordinates with high integrity and virtuous deeds at the military base. Being deeply touched by his morality and virtue, the people of Gongju(公州) established 'Youji general Nan Fangwei Jongdeokbi(〈遊擊將藍公種德碑〉)'. In addition, when he had his leisure time, he collected Korean Chinese poems from various figures and edited and published 'Chosun Poetry Collection(《朝鮮詩選全集》)', which he played a catalyst to promote high-quality Korean poems to Chinese literacy community.

NECESSARY AND SUFFICIENT CONDITIONS FOR THE EXISTENCE OF SOLUTIONS TO OPERATOR EQUATIONS

  • Park, Sehie
    • Bulletin of the Korean Mathematical Society
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    • v.27 no.2
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    • pp.151-155
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    • 1990
  • Recently, H.Z.Ming [7] obtained a necessary and sufficient condition for the existence of a solution to a general operator equation. In the present paper, we obtain such conditions in general forms and give some examples. We begin with the well-known Fan-Browder fixed point theorem, from which we deduce two general theorems on such necessary and sufficient conditiions. We give some examples of such conditions, which are improved versions of fixed point theorems of Halpern-Bergman [5], Ky Fan [3], [4], Kaczynski [6], Reich [9], Schauder [10], Tychonoff [11], and Ming [7]. In fact, we restate Ming's result in its correct form. The following is known as the Fan-Browder fixed point theorem [1], [2].

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Could Tumor Size Be A Predictor for Papillary Thyroid Microcarcinoma: a Retrospective Cohort Study

  • Wang, Min;Wu, Wei-Dong;Chen, Gui-Ming;Chou, Sheng-Long;Dai, Xue-Ming;Xu, Jun-Ming;Peng, Zhi-Hai
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8625-8628
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    • 2016
  • Background: Central lymph node metastasis(CLNM) is common in papillary thyroid microcarcinoma (PTMC). The aim of this study was to define the pathohistologic risk grading based on surgical outcomes. Materials and Methods: Statistical analysis was performed to figure out the optimal cut-off values of size in preoperative ultrasound images for defining the risk of CLNM in papillary thyroid microcarcinoma. Receiver operating characteristic curves (ROC) studies were carried out to determine the cutoff value(s) for the predictor(s). All the patients were divided into two groups according to the above size and the clinic-pathological and immunohistochemical parameters were compared to determine the significance of findings. Results: The optimal cut-off value of tumor size to predict the risk of CLNM in papillary thyroid microcarcinoma was 0.575 cm (area under the curve 0.721) according to the ROC curves. Significant differences were observed on the multifocality, extrathyroidal extension and central lymph node metastasis between two groups which were divided according to the tumor size by the cutoff values. Patients in two groups showed different positive rate and intensity of Ki67. Conclusions: The size of PTMC in ultrasound images are helpful to predict the aggressiveness of the tumors, it could be an easy predictor for PTMC prognosis and assist us to choose treatment.

The Re-inspection on The Explanatory Model ofXi Ming of Chu Hsi'sThought of "Li Yi Fen Shu" (朱熹 「理一分殊」 的 <西銘> 詮釋模式再考察)

  • Lin, Le-chang
    • Journal of Korean Philosophical Society
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    • v.141
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    • pp.167-185
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    • 2017
  • Chu Hsi inherited the proposition of Cheng Yi, and it spent him over ten years to finish writing the works of Xi Ming Jie, thus, making the thought of "Li Yi Fen Shu" bethe explanatory model of Xi Ming, therefore, playing the role to determine the tone of Xi Ming. At first, the thought of "Li Yi Fen Shu is a concept to embody the ethical significance of Xi Ming. But in terms of all the discussion about "Li Yi Fen Shu" of Chu Hsi in his life, this proposition is not only for the ethical significance of Xi Ming, but also includes much more general philosophical significance, revealing the general and special relationship of things. The former is the narrow "Li Yi Fen Shu", but the latter is the generalized one. This article won't discuss the generalized one, and it will take the narrow one as the research object. In the past research in academic circles, some scholars thinks that the proposition of "Li Yi Fen Shu" accords with the aim of Xi Ming, some others don't think so. Contrary to both of the two views, this article thinks that there is some conformity and inconformity between the explanatory model of "Li Yi Fen Shu" of Chu Hsi and the aim of Xi Ming. In other words, Contributions and limitations coexist when Chu Hsi explains Xi Ming in the model of "Li Yi Fen Shu", and there is not only the development to the intention of Xi Ming, but alsothe far meaning away from the aim of Xi Ming.