• 한국에너지공학회:학술대회논문집
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• 한국에너지공학회 1999년도 추계 학술발표회 논문집
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• pp.107-112
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• 1999

증기터빈 및 발전기의 특성을 그대로 모사 하는 PC 기반의 시뮬레이터를 개발하였으며, 사용자가 개발된 시뮬레이터의 기능들을 적절하고 편리하게 사용할 수 있도록 인간공학의 원칙을 고려하여 설계하였다. 이를 위해 시뮬레이터가 가져야 하는 기능들을 시험절차 및 운전 절차를 분석하여 도출하였으며 그 기능들을 각 사용자 인터페이스의 설계 목적에 맞도록 적절하게 배치하였다. 본 논문에서 소개하고자 하는 사용자 인터페이스는 Main Window에서 항상 감시가 가능하도록 설계된 Mimic Display, Information Tiles Display로 시뮬레이터 사용자 인터페이스의 핵심이라고 할 수 있다.

• 한국방사선학회논문지
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• 제12권1호
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• pp.71-78
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• 2018

본 연구에서는 인체 모사 조형물을 3차원 프린팅으로 출력한 사례를 보고하고자 하였다. 재료는 용융적층방식의 개인용 3차원 프린터 장비와 폴리락트산을 소재로 사용하였다. 3차원 인체 모사 조형물 출력은 모델링하는 단계, 평면화 작업과 G-code 변환 단계,출력변수 설정 단계, 3D 출력단계, 마지막으로 후처리 단계 순으로 진행하였으며, 학생들의 학습만족도(해부학인지도, 수업흥미도)를 리커트 5 점 척도로 조사하였다. 그 결과, 총 20가지의 3차원 인체 모사 조형물을 성공적으로 출력하였다. 총 출력소요시간은 11,691분(194시간 85분)이었으며 평균 출력소요시간은 584.55분(9시간 7분)이었다. 이에 소요된 필라멘트량은 총 2,390.2 g 이었으며 평균 119.51 g 이 소요되었다. 학습만족도의 해부학인지도는 평균 4.6 점, 수업흥미도는 평균 4.5 점으로 높은 것으로 나타났다. 앞으로 3차원 프린팅 기술은 영상해부학 교육의 학습효과를 높여줄 수 있으리라 기대한다.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.68.1-68
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• 2003

When plants are infected by plant pathogens, typical disease symptom termed lesion, appears in compatible interaction. Whereas, in incompatible interactions, only small speck of lesions are visible on the leaf surfaces. Hypersensitive response (HR) of plant which is the result of infection by incompatible pathogens, is a well known defense response inducing rapid cell death resulting in complete resistance. However, some rice mutants show spontaneous disease symptoms during the growth stages without interaction with pathogens. We investigated the spontaneous cell death mutant called Blast Lesion Mimic(BLM) generated by EMS mutation, on the relationship with the hypersensitive response as well as resistant characteristics. Accumulation of phenolic compounds were detected around the lesions as lesions develop on leaf surface. Activation of PR gene was detected before the lesion appeared, and that result indicates the defense-related response are started earlier than lesion formation. The BLM mutant showed resistant response to inoculation of Magnaporthe grisea KJ201 with which the wild type Hwacheong is totally susceptible. Informations on the formation of spontaneous lesions and detail analysis of lesion mimic mutants and related genes are very limited to date. It is really important to understand the phenomenon of the defense-related lesion formation for developing resistant cultivar for rice blast pathogens

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2004년도 The 2004 KSPP Annual Meeting & International Symposium
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• pp.48-52
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• 2004

We have found the role of rice mitogen-activated protein kinase kinase kinase (MAPKKK), OsEDR1, as controling hypersensitive response (HR) and increased disease resistance to rice blast fungus Magnaporthe grisea. Generation of transgenic rice plants through introduction of the over-expression construct of OsEDR1 using Agrobacterium-mediated transformation results in lesion mimic phenotype. Up-regulation of defense mechanism was detected through detection of increased transcription level of rice PBZ1 and PR1a. Inoculation of rice blast fungus on the lesion mimic transgenic lines displayed significantly increased resistance. The disease symptoms were arrested like HR responses which are commonly detected in the incompatible interactions. High accumulation of phenolic compounds around developing lesions was detected under UV light. There was variation among transgenic lines on the timing of lesion progression as well as the lesion numbers on the rice leaves. Transgenic lines with few lesions also show increased resistance as well as equal amount of grain yields compared to that of wild type rice cultivar Nipponbare. This is the first report of the MAPKKK as a positive regulator molecule on defense mechanism through inducing HR-like cell death lesion mimic phenotype. The application of OsEDR1 is highly expected for the development of resistant cultivars against rice pathogens.

• 한국정보통신학회논문지
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• 제15권8호
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• pp.1756-1763
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• 2011

본 연구에서는 생물학적 모방에 따른 물고기 로봇의 직진유영에 관한 연구로써, Liu 등이 제안한 꼬리 모션 함수를 푸우리에 급수 전개의 7차 항까지 고려한 제안된 방법과 일반적인 사인함수만으로 근사한 방법과 비교하여 모의실험 하였다. 일반적으로 로봇 물고기의 꼬리 링크의 길이가 길어지고 링크가 많을 경우, 로봇 물고기의 꼬리 모션 함수의 말단 회전 관절 궤적은 사인 함수의 모양과 매우 다르다. 그러므로 로봇 물고기의 꼬리 궤적을 단순한 푸우리에 급수 전개의 기본파 성분만으로 근사하기에는 문제가 있다. 제안된 방법과 일반적인 사인함수만으로 근사한 방법의 모의실험 결과 제안된 방법이 로봇 물고기의 추력과 속도에서 10%정도 뛰어남을 보였다.

• KIEE International Transactions on Power Engineering
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• 제5A권2호
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• pp.138-143
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• 2005

During faults, the voltage and current signals available to the relay are affected by the decaying dc component and harmonics. In order to make appropriate and accurate decisions, most of the relaying algorithms require the fundamental frequency phasor information that is immune to decaying dc effect and harmonics. The conventional Fourier ph as or estimation algorithm is affected by the presence of decaying-exponential transients in the fault signal. This paper presents a modified Fourier algorithm, which effectively eliminates the decaying dc component and the harmonics present in the fault signal. The decaying dc parameters are estimated by means of an out-of-band filtering technique. The decaying dc offset and harmonics are removed by means of a simple computational procedure that involves the design of two sets of Orthogonal digital OFT filters tuned at different frequencies and by creating three off-line look-up tables. The technique was tested for different decay rates of the decaying dc component. It was also compared with the conventional mimic plus the full cycle OFT algorithm. The results indicate that the proposed technique has a faster convergence to the desired value compared to the conventional mimic plus OFT algorithms over a wide range of decay rates. In all cases, the convergence to the desired value was achieved within one cycle of the power system frequency.

• Archives of Plastic Surgery
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• 제48권3호
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• pp.278-281
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• 2021

Facial palsy (FP) is a functional disorder of the facial nerve involving paralysis of the mimic muscles. According to the principle "time is muscle," early surgical treatment is tremendously important for preserving the mimic musculature if there are no signs of nerve function recovery. In a 49-year-old female patient, even 19 months after onset of FP, successful neurotization was still possible by a V-to-VII nerve transfer and cross-face nerve grafting. Our patient suffered from complete FP after vestibular schwannoma surgery. With continuous application of electrostimulation (ES) therapy, the patient was able to bridge the period between the first onset of FP and neurotization surgery. The significance of ES for mimic musculature preservation in FP patients has not yet been fully clarified. More attention should be paid to this form of therapy in order to preserve the facial musculature, and its benefits should be evaluated in further prospective clinical studies.

• BMB Reports
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• 제55권2호
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• pp.104-109
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• 2022

Skeletal myogenesis is essential to keep muscle mass and integrity, and impaired myogenesis is closely related to the etiology of muscle wasting. Recently, miR-141-3p has been shown to be induced under various conditions associated with muscle wasting, such as aging, oxidative stress, and mitochondrial dysfunction. However, the functional significance and mechanism of miR-141-3p in myogenic differentiation have not been explored to date. In this study, we investigated the roles of miR-141-3p on CFL2 expression, proliferation, and myogenic differentiation in C2C12 myoblasts. MiR-141-3p appeared to target the 3'UTR of CFL2 directly and suppressed the expression of CFL2, an essential factor for actin filament (F-actin) dynamics. Transfection of miR-141-3p mimic in myoblasts increased F-actin formation and augmented nuclear Yes-associated protein (YAP), a key component of mechanotransduction. Furthermore, miR-141-3p mimic increased myoblast proliferation and promoted cell cycle progression throughout the S and G2/M phases. Consequently, miR-141-3p mimic led to significant suppressions of myogenic factors expression, such as MyoD, MyoG, and MyHC, and hindered the myogenic differentiation of myoblasts. Thus, this study reveals the crucial role of miR-141-3p in myogenic differentiation via CFL2-YAP-mediated mechanotransduction and provides implications of miRNA-mediated myogenic regulation in skeletal muscle homeostasis.

• 대한전자공학회논문지TC
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• 제42권5호
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• pp.55-60
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• 2005

본 논문에서는 cascode 하모닉 발생기를 이용하여 V-band MIMIC (Millimeter-wave Monolithic Integrated Circuit) quadruple subharmonic 믹서를 설계 및 제작하였다. 고변환 이득 특성을 위하여 cascode 하모닉 발생기를 제안하였다. 제안된 cascode 하모닉 발생기는 기존의 multiplier 구조의 비해 평균 2.9 dB 및 최대 4 dB의 높은 4차 하모닉 출력 특성을 나타내었다. 제작된 V-band subharmonic 믹서의 측정결과 14.5 GHz LO 신호를 13 dBm의 크기로 입력하였을 때 3_4 dB의 높은 변환이득 특성을 얻었다. 또한 -53.6 dB의 LO-to-IF, -46.2 dB의 우수한 LO-to-RF 격리 특성을 나타내었다. 제작된 밀리미터파 subharmonic 믹서는 기존에 발표된 밀리미터파 대역의 subharmonic 믹서에 비해 우수한 변환이득 특성을 나타내었다.

• 대한전자공학회논문지TC
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• 제44권7호통권361호
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• pp.105-111
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• 2007

본 논문에서는 W-band($75{\sim}110\;GHz$) 주파수 영역에서 동작하는 CPW(Coplanar Waveguide) 구조의 3-dB 방향성 커플러를 MIMIC(Millimeter-wane Monolithic Integrated Circuit) 공정기술로 설계 및 제작하였다. 강한 결합계수 특성을 갖는 edge-coupled CPW 라인은 서로 다른 우 기 모드 위상속도에 의해 좋지 않은 방향성을 갖는다. 이를 극복하기 위하여 같은 우 기 위상속도를 갖는 edge-coupled CPW 라인을 2단으로 평행하게 연결하여 3-dB의 강한 커플링을 유도할 수 있는 Tandem 구조를 W-band에서 제안하였다. 제안된 Tandem 커플러는 기존의 다층기판 구조나 와이어 본딩 구조가 아닌 에어브리지 MIMIC 공정기술을 통해서 단일평면상에 제작되었다. 제작된 커플러는 $75{\sim}100\;GHz$의 넓은 주파수 영역에서 $2.9{\sim}3.6\;dB$의 결합계수와 $91.2{\pm}2.9^{\circ}$의 우수한 위상차 특성을 나타내었다.