• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7871-7874
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• 2015

Background: There is no consensus regarding the selection of treatment options for hepatocellular carcinoma (HCC) after initial transarterial chemoembolization (TACE). This meta-analysis aimed to explore the survival benefit of hepatic resection after initial TACE for the treatment of HCC. Materials and Methods: We searched three major databases to identify all relevant papers comparing the outcomes of hepatic resection after initial TACE versus TACE alone for the treatment of HCC. Hazard ratios (HRs) with 95% confidence intervals (95%CIs) were calculated to evaluate the survival benefit of hepatic resection after initial TACE over TACE alone. Results: Three of 2037 initially identified papers were included. All of them were cohort studies from Asia. There was a significantly better overall survival (OS) in patients undergoing hepatic resection after initial TACE than in those undergoing TACE alone (HR=0.63, 95%CI=0.52-0.76, P<0.00001). The heterogeneity among studies was not statistically significant (P=0.96; I2=0%). Conclusions: Hepatic resection could improve the OS of HCC patients treated with initial TACE. Further randomized controlled trials should be necessary to identify the target population for the sequential use of hepatic resection after initial TACE and to compare the outcomes between patients undergoing hepatic resection after initial TACE session versus those undergoing TACE alone.

• 벤처창업연구
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• 제17권2호
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• pp.115-128
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• 2022

본 연구는 전역(예정)장병을 대상으로 하는 육군 창업지원 프로그램이 군 복무만족도에 미치는 영향 분석에 관하여 연구하고자 한다. 또한 육군이 지원하고 추진하는 프로그램인 창업경진대회, 창업동아리 멘토링, 찾아가는 창업캠프, 창업사관학교 등 장병들이 프로그램 참여로 기대되는 군 복무만족도 대해 연구하고자 하였다. 본 프로그램의 취지는 전역(예정)장병들이 육군 창업지원 프로그램 참여를 통해 개인의 군 복무기간을 경력단절이 아닌 '꿈과 희망을 열어주는 기회의 시간'으로 활용 할 수 있도록 하였으며, 군 복무만족도 향상이 될 수 있도록 추진되었다. 이를 통해 전역(예정)장병 대상 정부기관 및 지자체의 창업지원 프로그램 확산과 청년들의 개인역량 강화를 확대하기 위한 방안을 제시하고자 한다. 연구를 위해 독립변수로는 육군 창업지원 프로그램인 창업경진대회, 창업동아리 멘토링(찾아가는 창업캠프), 창업사관학교로 하였고, 통제변수로는 참여자의 신분, 전역 후 진로 등 인구통계학적 요소를 설정하였다. 실증분석 결과 창업지원 프로그램이 군 복무만족도에 직접적인 영향을 미치는 것으로 위계적 회귀분석의 통계적 결과가 유의미하게 나타났다. 하지만 통제변수인 참여자의 신분, 전역 후 진로에 따라 창업지원 프로그램의 군 복무만족은 차이가 발생하는 것으로 나타났다. 본 연구의 시사점은 육군이 국가·사회와의 인재육성 연결자로서 장병들에게 군 복무기간 동안 개인역량을 강화할 수 있는 기회로 실질적으로 도움이 되는 프로그램임을 입증한다고 볼 수 있다. 또한 정부 및 지자체의 전역(예정)장병 대상 창업지원 사업의 확대 필요성에 대해 실증적 결과를 제시함으로써 청년 고용률 및 지원사업 개선에 도움을 주고자 한다.

• 한국산림과학회지
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• 제94권2호통권159호
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• pp.117-120
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• 2005

This study was conducted to estimate population size and investigate habitat characteristics for the conservation and management of Amur goral Nemorhaedus caudatus raddeanus in DMZ (Demilitarized Zone) of Gangwon Province in South Korea from November 2003 to May 2004. The Amur gorals counting were carried out by assistance of military soldiers who guards the southern boundary of DMZ. Four hundred sixty individuals were estimated as total population size in DMZ of Gangwon Province. Deciduous forest, rocky area and coniferous forest were dominant land cover types in habitat of Amur goral. DMZ and its vicinity of Gangwon Province are very important areas for the conservation of this species. It is needed to establish management plan for the conservation of Amur goral and their habitats in DMZ.

• 한국국방경영분석학회지
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• 제29권2호
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• pp.26-44
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• 2003

This study Is to forecast the damage of smallpox as a biological weapon and to measure the effect of potential responses (quarantine, vaccination and cure) to the spread of smallpox infection when a smallpox bioterrorism attack occurs. We designed the smallpox spreading simulation model through the literature study on a basis of some existing infectious disease models such as SIR, SEIR model by using Vensim program. In order to evaluate the performance of responses to smallpox, we measure the total infection population, infection sustaining duration, average infection rate and the infection spreading behavior of the smallpox. This study can help those who are related to the bioterrorism forecast the present and possible demage, and take more effective actions for minimizing the damage by smallpox bioterrorism.

• The Korean Journal of Pain
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• 제27권1호
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• pp.3-15
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• 2014

As our population ages and the rate of spine surgery continues to rise, the use epidural lysis of adhesions (LOA) has emerged as a popular treatment to treat spinal stenosis and failed back surgery syndrome. There is moderate evidence that percutaneous LOA is more effective than conventional ESI for both failed back surgery syndrome, spinal stenosis, and lumbar radiculopathy. For cervical HNP, cervical stenosis and mechanical pain not associated with nerve root involvement, the evidence is anecdotal. The benefits of LOA stem from a combination of factors to include the high volumes administered and the use of hypertonic saline. Hyaluronidase has been shown in most, but not all studies to improve treatment outcomes. Although infrequent, complications are more likely to occur after epidural LOA than after conventional epidural steroid injections.

• 한국국방경영분석학회지
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• 제22권2호
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• pp.126-138
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• 1996

The statistical control chart has been proven to be the effective tool most widely used in the manufacturing industry for monitoring and controlling the manufacturing processes. However, the Shewhart chart sometimes gives us false information when the distribution of quality characteristics is skewed. Therefore, it cannot serve as the universal quality control chart if there exist odd events in the manufacturing process. The objective of this study is thus to develop the new technique for constructing the limits of quality control chart based on a sample median and range when the distribution of the underlying population is skewed. This new control chart can effectively solve and manage the processes which have the non-normally distributed quality characteristics frequently occurring in the practical situation.

• 한국군사과학기술학회지
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• 제15권4호
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• pp.442-449
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• 2012

Cognitive Radio(CR) is the technology that allocates the frequency by using dynamic spectrum access. We proposed a model to calculate the optimal level of the cognitive radiotelegraph, where secondary users opportunistically share the spectrum with primary users through the spectrum sensing. When secondary user with cognitive radio detects the arrival of a primary user in its current channel, the secondary user moves to the idle channel or be placed in the virtual queue. We assume that the primary users have finite buffers and the population of secondary users is finite. Using a two-dimensional Makov model with preemptive priority queueing, we could derive the blocking and waiting probability as well as the optimal level of cognitive radiotelegraph under a various range of parameter circumstances.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5145-5151
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• 2013

Background: Numerous carcinogens and reactive oxygen species (ROS) may cause DNA damage including oxidative base lesions that lead to risk of nasopharyngeal carcinoma. Genetic susceptibility has been reported to play a key role in the development of this disease. The base excision repair (BER) pathway can effectively remove oxidative lesions, maintaining genomic stability and normal expression, with X-ray repair crosscomplementing1 (XRCC1), 8-oxoguanine glycosylase-1 (OGG1) and apurinic/apyimidinic endonuclease 1 (APE1) playing important roles. Aims: To analyze polymorphisms of DNA BER genes (OOG1, XRCC1 and APE1) and explore their associations, and the combined effects of these variants, with risk of nasopharyngeal carcinoma. Materials and Methods: We detected SNPs of XRCC1 (Arg399Gln), OGG1 (Ser326Cys), APE1 (Asp148Glu and -141T/G) using the polymerase chain reaction (PCR) with peripheral blood samples from 231 patients with NPC and 300 healthy people, furtherly analyzing their relations with the risk of NPC in multivariate logistic regression models. Results: After adjustment for sex and age, individuals with the XRCC1 399Gln/Gln (OR=1.96; 95%CI:1.02-3.78; p=0.04) and Arg/Gln (OR=1.87; 95%CI:1.29-2.71; p=0.001) genotype variants demonstrated a significantly increased risk of nasopharyngeal carcinoma compared with those having the wild-type Arg/Arg genotype. APE1-141G/G was associated with a significantly reduced risk of NPC (OR=0.40;95%CI:0.18-0.89) in the smoking group. The OR calculated for the combination of XRCC1 399Gln and APE1 148Gln, two homozygous variants, was significantly additive for all cases (OR=2.09; 95% CI: 1.27-3.47; p=0.004). Conclusion: This is the first study to focus on the association between DNA base-excision repair genes (XRCC1, OGG1 and APE1) polymorphism and NPC risk. The XRCC1 Arg399Gln variant genotype is associated with an increased risk of NPC. APE1-141G/G may decrease risk of NPC in current smokers. The combined effects of polymorphisms within BER genes of XRCC1 399Gln and APE1 148Gln may contribute to a high risk of nasopharyngeal carcinoma.

• 문화기술의 융합
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• 제8권2호
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• pp.203-208
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• 2022

영국은 테러와의 전쟁 시기 출산율 저하로 병역 가능자원이 감소하고 모병율이 저하되었으나, IS와 러시아로부터 발생하는 복합적인 안보위협이 점차 가중되는 상황에 직면하였다. 영국군은 이와 같은 도전을 극복하기 위한 방책의 하나로 기존의 사회적 보수성을 타파하고 여성인력을 근접전투 직위에 보직하는 정책을 추진하였다. 이를 위해, 영국군은 여군 활용 사례 발굴, 종단연구, 전투실험 등을 통해 군내 공감대를 형성하였고, 이후 사회적 공감대를 형성하기 위해 국민 의견을 수렴하기 위해 전략적 소통을 진행하였다. 이와 더불어, 근접전투를 수행하는 전투원이라면 누구나 통과해야 할 전투체력 평가체계를 구축하여 정책의 신뢰성을 증진시켰다. 우리나라도 미중 패권경쟁이 가속화되는 가운데 인구절벽으로 인한 병역 가능자원의 감소로 안보위협이 가중되고 있다. 따라서 영국군 사례는 우리에게 적지 않은 시사점과 향후 여성인력 정책 수립에 필요한 방향성을 제공할 것으로 보인다.

• Journal of the Korean Statistical Society
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• 제5권2호
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• pp.143-158
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• 1976

The purpose of this article is, first, to argue that the fertility cannot be reduced rapidly through widerspread diffusion of contraceptive practices which has been the main drive of the national policy in population control, because there involves the inescapable externalites in procreation, second, family sizes tend to be larger because of the financial externalities arising from government subsidies to families with children, and finally, the decreasing relative risk aversion of households with wealth may induce the poor to have large family sizes.