• Title/Summary/Keyword: Mild Condition

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Treatment of Lymphocytic Gastritis with Cyclosporine in a Cat (고양이 림프구성 위염에서 싸이클로스포린을 이용한 치료 증례)

  • Lee, Hwajoon;Park, So-Young;Ahn, Byeongwoo;Yang, Mhan-Pyo;Kang, Ji-Houn
    • Journal of Veterinary Clinics
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    • v.31 no.2
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    • pp.108-111
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    • 2014
  • A 7-year-old spayed female domestic shorthair cat was referred for chronic intermittent vomiting. The frequency of vomiting increased recently, and the cat showed anorexia at presentation. There were no remarkable abnormalities on the blood analyses and diagnostic imaging. However, the endoscopic examination revealed focal erosions of the gastric body mucosa, and subsequent multiple biopsies were obtained. Histopathologic examination indicated mild to moderate lymphocytic gastritis. The vomiting was completely disappeared 7 days after the administration with prednisolone (PDS). However, because of side effects caused by the long-term PDS administration, cyclosporine was added on the prescription with tapered dose of PDS. The dog's condition improved with continued cyclosporine treatment, and no further vomiting and anorexia episodes have been noted. This case describes the successful management with administration of cyclosporine in feline lymphocytic gastritis.

Changes of BCTMP Fibers and Handsheets Properties by the Treatment of LB DES at Different Molar Ratios (상이한 몰 비율의 LB 공융용매 처리에 따른 BCTMP 섬유 및 수초지 특성의 변화)

  • Choi, Kyoung-Hwa;Nam, Yun-Seok;Lee, Myoung-Ku;Ryu, Jeong-Yong
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.48 no.1
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    • pp.75-81
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    • 2016
  • This study was conducted to investigate the effects of deep eutectic solvent (DES) treatment on BCTMP fibers and handsheets properties. DES was prepared using lactic acid and betaine (LB), and the molar ratio of these two components mixtures was controlled to 2:1 (LB 2:1) and 5:1 (LB 5:1). As results, 2% of BCTMP pulp (o.d. weight) was extracted when it was treated by LB 5:1 at $50^{\circ}C$ for 12 hours, stirring constantly at 120 rpm. In contrast, lignin was not extracted when BCTMP was mildly treated by the LB DES mixed with 50% of distilled water at the reacting condition of temperature $60^{\circ}C$ for 2 hours using water bath. These results indicate that conditioned water content and adequate reaction time are needed to achieve effective extraction of lignin. It was also found that stiffening of cellulose fiber due to the mild treatment of LB DES to BCTMP fiber leads to the increase of paper bulk without the loss of strength.

Two Cases of Surgical and Medical Treatment of Infectious Intracranial Aneurysms - Case Report - (감염성 두개강내 동맥류의 수술 및 내과적 치험 2례 - 증 례 보 고 -)

  • Ban, Sung Soo;Ahn, Chi Sung;Jung, Myung Hun;Choe, Il Seung;Choi, Sun Wook;Song, Kwan Young;Kang, Dong Soo
    • Journal of Korean Neurosurgical Society
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    • v.30 no.1
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    • pp.73-77
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    • 2001
  • Object : To determine whether to use surgical or medical therapy in treatment of infectious intracranial aneurysms, we reviewed two recent cases of infectious intracranial aneurysms and others known previous reports of aforementioned cases. Hence, we attempted to compare the validity and effectiveness of surgical and medical treatment. Method : Recently, we treated two cases of ruptured infectious intracranial aneurysms. In former case, the aneurysm was located distal to the middle cerebral artery in a patient with mild mitral regurgitation of the heart. In latter case, the aneurysm was multiple with varying hemorrhage. The hemorrhage was located bilaterally and a moderate mitral regurgitation and infective endocarditis were accompanied in this patient. Result : Due to the large size of the intracranial hematoma, stable medical condition, and easy resectability, we treated the former patient surgically. And, because of successive hemorrhage by multiple aneurysmal rupture, and the risk of heart failure, we treated the latter patient medically with serial follow-up angiography. Both patients are at present in good health. Conclusion : Because of the variability in associated factors, such as the patient's health, the number of lesions, location, anatomy of the aneurysms and the causative organism, each patient's care must be individualized and tailored to the patient's particular clinical situation.

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Wave Attenuation due to Water-Front Vegetation (수변식생에 의한 파랑감쇠 특성)

  • Lee, Seong-Dae
    • Journal of Navigation and Port Research
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    • v.32 no.5
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    • pp.341-347
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    • 2008
  • Recently, it has been widely recognized that water-front and coastal vegetations may have great value in supporting fisheries, protecting from wave attack, stabilizing the sea bed and maintaining good scenery. Hydrodynamic factors playa major role in the functions of water quality and ecosystems. However, the studies on numerical and analytical process of wave propagation are few and far behind compared to those on the hydrodynamic roles of water-front vegetations. In this study, in order to express wave attenuation into water-front vegetation, a numerical model based on the unsteady mild slope equation is developed. This result is compared with an analytical model for describing the wave attenuation by assumed simple long wave condition. Based on both the analytical and numerical results, the physical properties of the wave attenuation are examined under various wave, geometric and vegetation conditions. Through comparisons between the analytical and numerical results, the effects of the vegetation properties, wave properties and model parameters such as the momentum exchange coefficient have been clarified.

DEVELOPMENT AND COMPARISION OF RESIDUE ANALYSIS FOR BENOMYL IN BEAN AND BEAN SPROUTS (두류와 콩나물에서의 BENOMYL의 검색과 그 분리에 관한 연구)

  • Han, Ilkeun;Chai, Jeungyoung;Lee, Jayoung;Yeo, Ikhyun
    • Analytical Science and Technology
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    • v.7 no.3
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    • pp.395-402
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    • 1994
  • Benomyl(Methyl-1-(Butyl Carbamoyl)-Benzimidazole-2-yl-Carbamate) is widely used as pre- and post-harvest pesticide. It converts into MBC(Carbendarzime:Benzimidazole-2-yl-carbamate) and butyl-isocyanate in mild condition. In this study, three analytical methods for MBC were compared in view of detectability, correctness, and sensitivity. The first and second are HPLC analytical method employing the UV detection of MBC. Our new third method was modification of PFBB(pentafluoro-benzylbromide) derivatization method with GC-ECD & MSD. The average recoveries and detection limit of MBC in the newly modified method are 95% and $0.001{\mu}g/g$ in whole bean and bean sprouts respectively. This new method prevent pesticide analysis from misdetecting in bean and bean sprouts.

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Pharmacologic Management of Chronic Pain

  • Park, Hue-Jung;Moon, Dong-Eon
    • The Korean Journal of Pain
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    • v.23 no.2
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    • pp.99-108
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    • 2010
  • Chronic pain is a multifactorial condition with both physical and psychological symptoms, and it affects around 20% of the population in the developed world. In spite of outstanding advances in pain management over the past decades, chronic pain remains a significant problem. This article provides a mechanism- and evidence-based approach to improve the outcome for pharmacologic management of chronic pain. The usual approach to treat mild to moderate pain is to start with a nonopioid analgesic. If this is inadequate, and if there is an element of sleep deprivation, then it is reasonable to add an antidepressant with analgesic qualities. If there is a component of neuropathic pain or fibromyalgia, then a trial with one of the gabapentinoids is appropriate. If these steps are inadequate, then an opioid analgesic may be added. For moderate to severe pain, one would initiate an earlier trial of a long term opioid. Skeletal muscle relaxants and topicals may also be appropriate as single agents or in combination. Meanwhile, the steps of pharmacologic treatments for neuropathic pain include (1) certain antidepressants (tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitors), calcium channel ${\alpha}2-{\delta}$ ligands (gabapentin and pregabalin) and topical lidocaine, (2) opioid analgesics and tramadol (for first-line use in selected clinical circumstances) and (3) certain other antidepressant and antiepileptic medications (topical capsaicin, mexiletine, and N-methyl-d-aspartate receptor antagonists). It is essential to have a thorough understanding about the different pain mechanisms of chronic pain and evidence-based multi-mechanistic treatment. It is also essential to increase the individualization of treatment.

MEASUREMENT OF SURFACE TENSION OF MOLTEN METALS IN ARC WELDING

  • Shinobu Satonaka;Shigeo Akiyoshi;Inoue, Rin-taro;Kim, Kwang-Ryul
    • Proceedings of the KWS Conference
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    • 2002.10a
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    • pp.757-762
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    • 2002
  • Many reports have been shown that the buoyancy, electromagnetic force, surface tension, and gas shear stress are the driving forces of weld pool circulation in arc welding. Among them, the surface tension of molten metal plays an important role in the flow in weld pool, which are clarified by the specially designed experiments with small particles as well as the numerical simulations. The surface tension is also related to the penetration in arc welding. Therefore, a quantitative evaluation of surface tension is demanded for the development of materials and arc process control. However, there are few available data published on the surface tension of molten metals, since it depends on the temperature and the composition of materials. In this study, a new method was proposed for the evaluation of surface tension and its temperature dependence, in which it is evaluated by the equilibrium condition of acting forces under a given surface geometry, especially back surface. When this method was applied to the water pool and to the back surface of molten pool in the stationary gas tungsten arc welding of thin plate, following results were obtained. In the evaluation of surface tension of water, it was shown that the back surface geometry was very sensitive to the evaluation of surface tension and the evaluated value coincided with the surface tension of water. In the measurement of molten pool in the stationary gas tungsten arc welding, it was also shown that the comparison between the surface tension and temperature distribution across the back surface gave the temperature dependent surface tension. Applying this method to the mild steel and stainless steel plates, the surface tension with negative gradient for temperature is obtained. The evaluated values are well matched with ones in the published papers.

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Pathogenesis and Host Interaction of Foot-and-mouth Disease (구제역의 병인론과 숙주와의 상호작용)

  • Park, Jong-Hyeon;Lee, Kwang-Nyeong;Kim, Su-Mi;Ko, Young-Joon;Lee, Hyang-Sim;Cho, In-Soo
    • Journal of Veterinary Clinics
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    • v.28 no.1
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    • pp.113-121
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    • 2011
  • Foot-and-mouth disease (FMD) is a severe vesicular disease of cloven-hoofed animals including domesticated ruminants and pigs. Acute clinical signs may be mild in sheep and goats but are associated with lameness in pigs and mouth lesions with vesicles in cattle. The required condition for a successful pathogen appears to be the ability to counteract both the host innate and adaptive immune response. FMD virus (FMDV) inhibits the induction of antiviral molecules and interferes with the secretory pathway in the infected cell. The surface expression of Major Histocompatibility Complex (MHC) class I molecules is reduced in infected cells. Thus, the ability of the host to recognize and eliminate virus infected cells is decreased. Furthermore, FMDV infection results in a rapid, but transient lymphopenia, reducing the number of T and B cells, and affecting T cell function. The virus appears to premature apoptosis-mediated cell death because it has a very short replication cycle and is able to rapidly produce large amounts of virus. FMDV engages the host protective response at multiple steps to ensure its effective replication and pathogenesis. This review describes the recent pathological and immunological studies to overcome the powerful abilities of FMDV to counteract defense mechanism of host.

Transcatheter Intravascular Stent Placement in a Shih Tzu Dog with Refractory Pulmonic Stenosis (카테터를 통한 혈관스텐트 장착을 통한 심한 폐동맥협착증 치료 1례)

  • Kim, Hyun-Wook;Kim, Sung-Soo;Lee, Joon-Soek;Nam, So-Jeong;Choi, Ran;Hyun, Chang-Baig
    • Journal of Veterinary Clinics
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    • v.26 no.1
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    • pp.48-53
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    • 2009
  • A 4-year-old intact male Shih Tzu dog (5.4 kg of body weight) was referred with primary complaints of heart murmur and exercise intolerance. Diagnostic studies found severe valvular pulmonic stenosis (peak velocity of 6.4 m/s, pressure gradient 165 mmHg). The dog was treated with 3 cm (length) ${\times}$ 1.5 cm (diameter) of Palmaz biliary stent. The outcome of stent placement was favorable and remarkably reduced the severity of PS (6.4 m/s to 3.0 m/s of peak velocity). Clinical condition was remarkably improved with the absence of cardiac murmur, although mild pulmonic regurgitation existed from the day of stent placement. To our best knowledge, this case is the first clinical trial for treating PS with intravascular stent in Korea.

Analysis for the Effect of Channel Contraction for Sedimentation Reduction on the Flood Level and Bed Changes in the Lower Nakdong River (낙동강 하류의 퇴사저감을 위한 하폭축소방법이 홍수위변화 및 하상변동에 미치는 영향 분석)

  • Jang, Eun-Kyung;Ji, Un
    • Journal of Environmental Science International
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    • v.22 no.3
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    • pp.291-301
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    • 2013
  • Sediment from the upstream channel has been deposited near the Nakdong River Estuary Barrage (NREB) due to the mild slope and decreased velocity. The annual mechanical dredging to ensure the flood capacity has been performed to remove the deposited sediment. However, the dredging method is not considered as an effective countermeasure due to high cost and long time to operate. Therefore, many methods for sedimentation reduction have been proposed for NREB. Especially, the channel contraction method to mitigate sedimentation problem by changing the channel geometry from 2 km to 3 km upstream of NREB has been recently suggested as an effective countermeasure. However, there is the possibility that the channel contraction method induces flood level increase compared to original condition. Therefore, it is necessary to investigate quantitatively the flood level changes in the upstream and downstream section due to the channel contraction method for NREB. In this study, water level changes by 10% channel contraction of whole width has been evaluated using the HEC-RAS model and simulated with and without channel contraction for various flood discharge. As a result, water level in the section where the channel was contracted was decreased by 0.02 m and flood level at the upstream of channel contracted was increased up to 0.015 m for the 500-year flood.